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NO20080860L - Substituert propanamidderivat og farmasoytisk preparat som inneholder dette - Google Patents

Substituert propanamidderivat og farmasoytisk preparat som inneholder dette

Info

Publication number
NO20080860L
NO20080860L NO20080860A NO20080860A NO20080860L NO 20080860 L NO20080860 L NO 20080860L NO 20080860 A NO20080860 A NO 20080860A NO 20080860 A NO20080860 A NO 20080860A NO 20080860 L NO20080860 L NO 20080860L
Authority
NO
Norway
Prior art keywords
pharmaceutical composition
composition containing
substituted
propanamide derivative
substituted propanamide
Prior art date
Application number
NO20080860A
Other languages
English (en)
Inventor
Kazumasa Aoki
Koji Suda
Tomio Kimura
Kentoku Gotanda
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of NO20080860L publication Critical patent/NO20080860L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C07C233/31—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Et formål ved oppfinnelsen er å tilveiebringe et substituert propanamidderivat eller et farmakologisk akseptabelt salt derav, som er anvendbart som et preventivt middel eller et terapeutisk middel mot en sykdom som er relatert til benmetabolisme. Oppfinnelsen er rettet mot et farmasøytisk preparat som inneholder som en aktiv bestanddel en forbindelse med den generelle formel (I): hvor R1 er en C6-C10-arylgruppe som kan være ytterligere substituert; R2 er en C6-C10-arylgruppe som kan være ytterligere substituert, og farmakologisk akseptable salt derav.
NO20080860A 2005-07-19 2008-02-18 Substituert propanamidderivat og farmasoytisk preparat som inneholder dette NO20080860L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005208036 2005-07-19
PCT/JP2006/314144 WO2007010885A1 (ja) 2005-07-19 2006-07-18 置換プロパンアミド誘導体及びそれを含む医薬組成物

Publications (1)

Publication Number Publication Date
NO20080860L true NO20080860L (no) 2008-04-18

Family

ID=37668765

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20080860A NO20080860L (no) 2005-07-19 2008-02-18 Substituert propanamidderivat og farmasoytisk preparat som inneholder dette

Country Status (15)

Country Link
US (1) US8344029B2 (no)
EP (1) EP1908466B1 (no)
JP (1) JP5311822B2 (no)
KR (1) KR20080027850A (no)
CN (1) CN101267813A (no)
AU (1) AU2006270914B2 (no)
BR (1) BRPI0613423A2 (no)
CA (1) CA2615991C (no)
IL (1) IL188839A (no)
MX (1) MX2008000971A (no)
NO (1) NO20080860L (no)
NZ (1) NZ565141A (no)
RU (1) RU2394560C2 (no)
TW (1) TWI371272B (no)
WO (1) WO2007010885A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI396543B (zh) * 2005-05-12 2013-05-21 Sankyo Co 取代丙烯醯胺衍生物及含有它之醫藥組成物
JP2011026201A (ja) * 2007-10-17 2011-02-10 Mitsubishi Tanabe Pharma Corp 光学活性ピロリル−コハク酸イミド誘導体の立体選択的な製造方法
RU2623034C1 (ru) * 2016-07-28 2017-06-21 Федеральное государственное бюджетное учреждение науки Иркутский институт химии им. А.Е. Фаворского Сибирского отделения Российской академии наук Противоопухолевое средство
US10968172B2 (en) 2017-05-15 2021-04-06 Mitobridge, Inc. USP30 inhibitors
CN117050045B (zh) * 2023-10-10 2023-12-22 长沙创新药物工业技术研究院有限公司 一种s构型羟丙基四氢吡喃三醇的合成方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5521737B2 (no) 1972-12-23 1980-06-12
IT1062206B (it) 1974-02-01 1983-09-20 Rotta Research Lab S P A A S Derivati della tirosina attivi sulla muscolatura liscia
US4621092A (en) 1982-07-22 1986-11-04 E. R. Squibb & Sons, Inc. Substituted proline compounds, composition and method of use
CA1297633C (en) * 1985-09-27 1992-03-17 Shosuke Okamoto Phenylalanine derivative and proteinase inhibitor
WO1998025949A1 (en) * 1996-12-09 1998-06-18 Proscript, Inc. Substituted 5-amino-1,3,4-thiadiazole-2-thiones
CA2279977A1 (en) 1997-02-04 1998-08-06 John S. Kiely 4-substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries
HUP0004400A3 (en) * 1997-11-05 2002-10-28 Novartis Ag Dipeptide nitriles, process for their preparation, pharmaceutical compositions comprising thereof and their use
AU4329399A (en) * 1998-07-30 2000-02-21 Warner-Lambert Company Tyrosine-derived compounds as calcium channel antagonists
GB9828442D0 (en) 1998-12-24 1999-02-17 Karobio Ab Novel thyroid receptor ligands and method II
DE10204951A1 (de) 2002-02-06 2003-08-14 Basf Ag Phenylalaninderivate als Herbizide
EP1482924B1 (en) 2002-03-05 2008-05-21 Merck Frosst Canada Ltd. Cathepsin cysteine protease inhibitors
AU2003282804A1 (en) 2002-09-20 2004-04-08 Axys Pharmaceuticals, Inc. 3-(3,5-disubstituted-4-hydroxyphenyl)propionamide derivatives as cathepsin b inhibitors
WO2004052921A1 (en) * 2002-12-05 2004-06-24 Axys Pharmaceuticals, Inc. Cyanomethyl derivatives as cysteine protease inhibitors
US20050154011A1 (en) * 2003-02-20 2005-07-14 The Procter & Gamble Company Tetrahydroisoquinolnyl sulfamic acids
US7109243B2 (en) 2003-03-24 2006-09-19 Irm Llc Inhibitors of cathepsin S
KR20060061300A (ko) 2003-06-13 2006-06-07 라보라토리오스 에스.에이.엘.브이.에이.티., 에스.에이. ＰＰＡＲγ 조절제로서의 벤즈아미드
GB0329584D0 (en) * 2003-12-20 2004-01-28 Tanabe Seiyaku Co Novel compounds
WO2005097103A2 (en) * 2004-04-01 2005-10-20 Axys Pharmaceuticals, Inc. Diabetes and metabolic syndrome therapy utilizing cathepsin b inhibitors
US7618981B2 (en) * 2004-05-06 2009-11-17 Cytokinetics, Inc. Imidazopyridinyl-benzamide anti-cancer agents

Also Published As

Publication number Publication date
IL188839A0 (en) 2008-04-13
TWI371272B (en) 2012-09-01
BRPI0613423A2 (pt) 2012-12-11
IL188839A (en) 2012-10-31
WO2007010885A1 (ja) 2007-01-25
TW200740428A (en) 2007-11-01
CA2615991C (en) 2011-02-08
AU2006270914B2 (en) 2011-01-20
KR20080027850A (ko) 2008-03-28
RU2394560C2 (ru) 2010-07-20
RU2008102132A (ru) 2009-07-27
MX2008000971A (es) 2008-03-27
EP1908466A1 (en) 2008-04-09
US20090292024A1 (en) 2009-11-26
AU2006270914A1 (en) 2007-01-25
EP1908466A4 (en) 2012-05-30
JPWO2007010885A1 (ja) 2009-01-29
US8344029B2 (en) 2013-01-01
NZ565141A (en) 2010-12-24
CN101267813A (zh) 2008-09-17
JP5311822B2 (ja) 2013-10-09
CA2615991A1 (en) 2007-01-25
EP1908466B1 (en) 2014-02-19

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