NO20080419L - Isokinolinderivater som inhibitorer av Rho-kinase - Google Patents
Isokinolinderivater som inhibitorer av Rho-kinaseInfo
- Publication number
- NO20080419L NO20080419L NO20080419A NO20080419A NO20080419L NO 20080419 L NO20080419 L NO 20080419L NO 20080419 A NO20080419 A NO 20080419A NO 20080419 A NO20080419 A NO 20080419A NO 20080419 L NO20080419 L NO 20080419L
- Authority
- NO
- Norway
- Prior art keywords
- rho kinase
- inhibitors
- isoquinoline derivatives
- derivatives
- piperidinyl
- Prior art date
Links
- 102000000568 rho-Associated Kinases Human genes 0.000 title abstract 3
- 108010041788 rho-Associated Kinases Proteins 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title 1
- 125000002183 isoquinolinyl group Chemical class C1(=NC=CC2=CC=CC=C12)* 0.000 title 1
- -1 6-piperidinyl-substituted isoquinoline Chemical class 0.000 abstract 1
- 102000011131 Myosin-Light-Chain Phosphatase Human genes 0.000 abstract 1
- 108010037801 Myosin-Light-Chain Phosphatase Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Oppfinnelsen angår 6-piperidinyl-substituerte isokinolinderivater med formel (I); anvendelige for behandling og/eller hindring av sykdommer assosiert med Rho-kinase og/eller Rho-kinase mediert fosforylering av myosinlettkjedefosfatase og sammensetninger som inneholder slike forbindelser.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1386805A | 2005-06-28 | 2005-06-28 | |
| PCT/EP2006/005648 WO2007000240A1 (en) | 2005-06-28 | 2006-06-13 | Isoquinoline derivatives as inhibitors of rho-kinase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20080419L true NO20080419L (no) | 2008-01-22 |
Family
ID=39226563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20080419A NO20080419L (no) | 2005-06-28 | 2008-01-22 | Isokinolinderivater som inhibitorer av Rho-kinase |
Country Status (1)
| Country | Link |
|---|---|
| NO (1) | NO20080419L (no) |
-
2008
- 2008-01-22 NO NO20080419A patent/NO20080419L/no unknown
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