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NO20070148L - Nye oksabispidinforbindelser og deres anvendelse ved behandling av forstyrrelser i hjerterytmen - Google Patents

Nye oksabispidinforbindelser og deres anvendelse ved behandling av forstyrrelser i hjerterytmen

Info

Publication number
NO20070148L
NO20070148L NO20070148A NO20070148A NO20070148L NO 20070148 L NO20070148 L NO 20070148L NO 20070148 A NO20070148 A NO 20070148A NO 20070148 A NO20070148 A NO 20070148A NO 20070148 L NO20070148 L NO 20070148L
Authority
NO
Norway
Prior art keywords
compounds
treatment
oxabispidin
new
cardiac arrhythmias
Prior art date
Application number
NO20070148A
Other languages
English (en)
Inventor
Annika Bjore
Fritiof Ponten
Christina Olsson
Ulrik Gran
Peter Bonn
Johan Kajanus
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32710059&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20070148(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20070148L publication Critical patent/NO20070148L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Det tilveiebringes forbindelser med formel I, hvor R1, R2, R3, R4, R41 til R46, A, B og G har betydninger som angitt i beskrivelsen, som er anvendelige ved forebygging og ved behandling av arytmi, spesielt atriell og ventrikulær arytmi.
NO20070148A 2004-06-15 2007-01-09 Nye oksabispidinforbindelser og deres anvendelse ved behandling av forstyrrelser i hjerterytmen NO20070148L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0401539A SE0401539D0 (sv) 2004-06-15 2004-06-15 New compounds
PCT/SE2005/000891 WO2005123748A1 (en) 2004-06-15 2005-06-13 Novel oxabispidine compounds and their use in the treatment of cardiac arrhythmias

Publications (1)

Publication Number Publication Date
NO20070148L true NO20070148L (no) 2007-01-09

Family

ID=32710059

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070148A NO20070148L (no) 2004-06-15 2007-01-09 Nye oksabispidinforbindelser og deres anvendelse ved behandling av forstyrrelser i hjerterytmen

Country Status (22)

Country Link
US (2) US7648985B2 (no)
EP (1) EP1765832B8 (no)
JP (1) JP2008502678A (no)
KR (1) KR20070039045A (no)
CN (2) CN101525339A (no)
AR (1) AR049823A1 (no)
AU (2) AU2005254924B2 (no)
BR (1) BRPI0512012A (no)
CA (1) CA2568895A1 (no)
DK (1) DK1765832T3 (no)
ES (1) ES2434043T3 (no)
IL (1) IL179560A0 (no)
MX (1) MXPA06014692A (no)
NO (1) NO20070148L (no)
RU (1) RU2379311C9 (no)
SE (1) SE0401539D0 (no)
SG (1) SG153822A1 (no)
TW (1) TW200612907A (no)
UA (1) UA85877C2 (no)
UY (1) UY28959A1 (no)
WO (1) WO2005123748A1 (no)
ZA (2) ZA200610418B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0401539D0 (sv) 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
KR20080021114A (ko) * 2005-06-13 2008-03-06 아스트라제네카 아베 심부정맥의 치료를 위한 신규한 옥사비스피딘 화합물
TW200734342A (en) * 2005-12-15 2007-09-16 Astrazeneca Ab New compounds for the treatment of cardiac arrhythmias
MX2010013192A (es) 2008-06-16 2010-12-17 Hoffmann La Roche Monoamidas heteroaromaticas como antagonistas de receptor orexinina.
TW201004963A (en) * 2008-07-03 2010-02-01 Targacept Inc Derivatives of oxabispidine as neuronal nicotinic acetylcholine receptor ligands
WO2010059119A1 (en) * 2008-11-21 2010-05-27 Astrazeneca Ab A combination of tert -butyl (2-{7- [2- (4-cyano-2- f luorophenoxy) ethyl] -9-oxa-3, 7-diazabicyclo [3.3.1] non-3- yl } ethyl) carbamate and certain antiarrhythmic benzofurans
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CN117384037B (zh) * 2023-12-13 2024-03-08 山东国邦药业有限公司 一种二氟乙酸乙酯的制备方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3196154A (en) * 1962-05-17 1965-07-20 Sterling Drug Inc 3-substituted-9-methyl-3, 9-diazabicyclo [3.3.1] nonanes
US3503939A (en) * 1967-03-29 1970-03-31 Du Pont Polyamides from heterocyclic diamines
CH488048A (de) 1969-06-12 1970-03-31 Inventa Ag Verfahren zur Herstellung von Polyesterfasern mit verbesserter Gummihaftung
DE2428792A1 (de) 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
JPS5772977A (en) 1980-10-23 1982-05-07 Dainippon Ink & Chem Inc Fluorine-containing diepoxy compound and its preparation
DE3112055A1 (de) 1981-03-27 1982-10-07 Basf Ag, 6700 Ludwigshafen Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel
DE3234697A1 (de) 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
US4533713A (en) * 1983-05-06 1985-08-06 Minnesota Mining And Manufacturing Company Fluoroaliphaticsulfonamides containing oxirane groups and/or N-β-hydroxyalkylene groups
PT88381B (pt) 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
DE3732094A1 (de) 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US5140033A (en) * 1989-04-03 1992-08-18 Bayer Aktiengesellschaft Antibacterial 5-alkylquinolonecarboxylic acids
US5110933A (en) 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them
FI100151B (fi) 1992-09-04 1997-09-30 Nokia Mobile Phones Ltd Tehonsäästö matkaviestimessä
US5294621A (en) * 1992-10-07 1994-03-15 Ortho Pharmaceutical Corporation Thieno tetrahydropyridines useful as class III antiarrhythmic agents
JPH06284071A (ja) 1993-01-27 1994-10-07 Casio Comput Co Ltd 無線受信機
US5468858A (en) 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
FR2713081B1 (fr) 1993-11-29 1996-01-12 Celsa Lg Filtre sanguin perfectionné à deux séries de pattes en pétales.
US5831099A (en) * 1995-03-10 1998-11-03 The United States Of America As Represented By The Secretary Of The Army Compounds of 1,5-disubstituted-3,7 diaza bicyclo 3.3.0! octanes and products containing the same
SE9704709D0 (sv) 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
BR0009651A (pt) 1999-04-09 2002-01-08 Astrazeneca Ab Composto, processo para a preparação de um composto, composição farmacêutica, uso de um composto, e, método para tratar artrite reumatóide e uma doença obstrutiva das vias aéreas
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
AR030756A1 (es) * 2000-10-02 2003-09-03 Astrazeneca Ab Compuesto de oxabispidina util en el tratamiento de arritmias cardiacas
SE0101323D0 (sv) * 2001-04-12 2001-04-12 Astrazeneca Ab New process
SE0101327D0 (sv) 2001-04-12 2001-04-12 Astrazeneca Ab New crystalline forms
SE0101324D0 (sv) * 2001-04-12 2001-04-12 Astrazeneca Ab New process
SE0201662D0 (sv) 2002-05-31 2002-05-31 Astrazeneca Ab Pharmaceutical combination
GB0223712D0 (en) 2002-10-14 2002-11-20 Astrazeneca Ab Chemical intermediate
SE0401540D0 (sv) * 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
SE0401539D0 (sv) 2004-06-15 2004-06-15 Astrazeneca Ab New compounds

Also Published As

Publication number Publication date
DK1765832T3 (da) 2013-10-21
UY28959A1 (es) 2006-01-31
CA2568895A1 (en) 2005-12-29
EP1765832A1 (en) 2007-03-28
US20090005558A1 (en) 2009-01-01
US20090270383A1 (en) 2009-10-29
CN1968956A (zh) 2007-05-23
AR049823A1 (es) 2006-09-06
IL179560A0 (en) 2007-05-15
SE0401539D0 (sv) 2004-06-15
SG153822A1 (en) 2009-07-29
AU2005254924B2 (en) 2009-08-27
US7648985B2 (en) 2010-01-19
EP1765832B8 (en) 2013-09-25
AU2005254924A1 (en) 2005-12-29
ZA200610418B (en) 2008-07-30
RU2006145202A (ru) 2008-07-20
CN101525339A (zh) 2009-09-09
RU2379311C9 (ru) 2010-05-27
ZA200710111B (en) 2009-08-26
BRPI0512012A (pt) 2008-02-06
MXPA06014692A (es) 2007-02-12
WO2005123748A1 (en) 2005-12-29
EP1765832B1 (en) 2013-08-14
KR20070039045A (ko) 2007-04-11
RU2379311C2 (ru) 2010-01-20
AU2009222548A1 (en) 2009-10-22
JP2008502678A (ja) 2008-01-31
UA85877C2 (uk) 2009-03-10
ES2434043T3 (es) 2013-12-13
TW200612907A (en) 2006-05-01

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