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NO20062591L - Difenylazetidinonderivater med kolesterolabsorpsjonsinhiberende aktivitet - Google Patents

Difenylazetidinonderivater med kolesterolabsorpsjonsinhiberende aktivitet

Info

Publication number
NO20062591L
NO20062591L NO20062591A NO20062591A NO20062591L NO 20062591 L NO20062591 L NO 20062591L NO 20062591 A NO20062591 A NO 20062591A NO 20062591 A NO20062591 A NO 20062591A NO 20062591 L NO20062591 L NO 20062591L
Authority
NO
Norway
Prior art keywords
cholesterol absorption
diphenyllazetidinone
derivatives
inhibitory activity
absorption inhibitory
Prior art date
Application number
NO20062591A
Other languages
English (en)
Inventor
Mikael Dahlstrom
Ann-Margret Lindqvist
Suzanne Alenfalk
Tore Skjaret
Malin Lemurell
Ingemar Starke
Fana Hunegnaw
Staffan Karlsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34714057&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20062591(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0329780A external-priority patent/GB0329780D0/en
Priority claimed from SE0401907A external-priority patent/SE0401907D0/xx
Priority claimed from SE0402785A external-priority patent/SE0402785D0/sv
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20062591L publication Critical patent/NO20062591L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Forbindelser med formel (I):. (hvor variable grupper er som definert i beskrivelsen), farmasøytisk akseptable salter, solvater, solvater av slike salter og promedikamenter derav, og anvendelse av dem som kolesterolabsorpsjonshemmere for behandling av hyperlipidemi, er beskrevet. Fremgangsmåter for fremstilling av dem, og farmasøytiske preparater inneholdende dem, er også beskrevet.
NO20062591A 2003-12-23 2006-06-06 Difenylazetidinonderivater med kolesterolabsorpsjonsinhiberende aktivitet NO20062591L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0329780A GB0329780D0 (en) 2003-12-23 2003-12-23 Chemical compounds
SE0401907A SE0401907D0 (sv) 2004-07-21 2004-07-21 Chemical compounds
SE0402785A SE0402785D0 (sv) 2004-11-15 2004-11-15 Chemical compunds
PCT/SE2004/001960 WO2005061452A1 (en) 2003-12-23 2004-12-21 Diphenylazetidinone derivates possessing cholesterol absorption inhibitory activity

Publications (1)

Publication Number Publication Date
NO20062591L true NO20062591L (no) 2006-09-20

Family

ID=34714057

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062591A NO20062591L (no) 2003-12-23 2006-06-06 Difenylazetidinonderivater med kolesterolabsorpsjonsinhiberende aktivitet

Country Status (15)

Country Link
US (1) US7871998B2 (no)
EP (1) EP1699759B1 (no)
JP (1) JP4688819B2 (no)
AR (1) AR047070A1 (no)
AT (1) ATE485267T1 (no)
AU (1) AU2004303742B2 (no)
BR (1) BRPI0418004A (no)
CA (1) CA2550215A1 (no)
DE (1) DE602004029715D1 (no)
IL (1) IL176158A0 (no)
NO (1) NO20062591L (no)
SA (1) SA04250427A (no)
TW (1) TW200526572A (no)
UY (1) UY28695A1 (no)
WO (1) WO2005061452A1 (no)

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GB0215579D0 (en) 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds
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JP2008546784A (ja) 2005-06-20 2008-12-25 シェーリング コーポレイション ヒスタミンｈ３アンタゴニストとして有用なピペリジン誘導体
UY29607A1 (es) * 2005-06-20 2007-01-31 Astrazeneca Ab Compuestos quimicos
AR057383A1 (es) * 2005-06-22 2007-12-05 Astrazeneca Ab Compuestos quimicos derivados de 2-azetidinona, formulacion farmaceutica y un proceso de preparacion del compuesto
MY148538A (en) 2005-06-22 2013-04-30 Astrazeneca Ab Novel 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions
AR054482A1 (es) * 2005-06-22 2007-06-27 Astrazeneca Ab Derivados de azetidinona para el tratamiento de hiperlipidemias
AR057380A1 (es) * 2005-06-22 2007-11-28 Astrazeneca Ab Compuestos quimicos derivados de 2-azetidinona y uso terapeutico de los mismos
SA06270191B1 (ar) * 2005-06-22 2010-03-29 استرازينيكا ايه بي مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
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US7871998B2 (en) 2011-01-18
DE602004029715D1 (de) 2010-12-02
ATE485267T1 (de) 2010-11-15
BRPI0418004A (pt) 2007-04-17
US20100099657A2 (en) 2010-04-22
US20080064676A1 (en) 2008-03-13
JP2007516280A (ja) 2007-06-21
WO2005061452A8 (en) 2006-04-06
SA04250427A (ar) 2005-12-03
UY28695A1 (es) 2005-07-29
AU2004303742A1 (en) 2005-07-07
EP1699759B1 (en) 2010-10-20
IL176158A0 (en) 2006-10-05
AR047070A1 (es) 2006-01-04
TW200526572A (en) 2005-08-16
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