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NO20055777L - Et 12-desaturasegen egnet for a endre nivaene av polyumettede fettsyrer i oljesyrerike gjaer - Google Patents

Et 12-desaturasegen egnet for a endre nivaene av polyumettede fettsyrer i oljesyrerike gjaer

Info

Publication number
NO20055777L
NO20055777L NO20055777A NO20055777A NO20055777L NO 20055777 L NO20055777 L NO 20055777L NO 20055777 A NO20055777 A NO 20055777A NO 20055777 A NO20055777 A NO 20055777A NO 20055777 L NO20055777 L NO 20055777L
Authority
NO
Norway
Prior art keywords
desaturase
fatty acids
oleic
levels
altering
Prior art date
Application number
NO20055777A
Other languages
English (en)
Other versions
NO20055777D0 (no
Inventor
Narendra S Yadav
Hongxiang Zhang
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of NO20055777D0 publication Critical patent/NO20055777D0/no
Publication of NO20055777L publication Critical patent/NO20055777L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Den foreliggende oppfinnelsen er relatert til en A12-fettsyredesaturase i stand til å katalysere omdannelsen av oljesyre til linolsyre (LA; 18:2). Nukleinsyresekvenser som koder for desaturasen, nukleinsyresekvenser som hybridiserer til disse, DNA-konstruksjoner som omfatter desaturasegenet, og rekombinante vertsmikroorganismer som uttrykker økte nivåer av desaturasen er beskrevet. Fremgangsmåter for å øke produksjon av spesifikke (d-3 og/eller (d-6 fettsyrer er beskrevet ved overekspresjon av A12-fettsyre- desaturasen eller ved å ødelegge det naturlige genet.
NO20055777A 2003-05-07 2005-12-06 Et 12-desaturasegen egnet for a endre nivaene av polyumettede fettsyrer i oljesyrerike gjaer NO20055777L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46867703P 2003-05-07 2003-05-07
US48420903P 2003-06-30 2003-06-30
PCT/US2004/014542 WO2004104167A2 (en) 2003-05-07 2004-05-07 A δ-12 desaturase gene suitable for altering levels of polyunsaturated fatty acids in oleaginous yeasts

Publications (2)

Publication Number Publication Date
NO20055777D0 NO20055777D0 (no) 2005-12-06
NO20055777L true NO20055777L (no) 2006-02-07

Family

ID=33479252

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055777A NO20055777L (no) 2003-05-07 2005-12-06 Et 12-desaturasegen egnet for a endre nivaene av polyumettede fettsyrer i oljesyrerike gjaer

Country Status (7)

Country Link
US (3) US7214491B2 (no)
EP (1) EP1620561A4 (no)
AU (1) AU2004242095A1 (no)
BR (1) BRPI0410681A (no)
CA (1) CA2523786A1 (no)
NO (1) NO20055777L (no)
WO (1) WO2004104167A2 (no)

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US8691555B2 (en) 2006-09-28 2014-04-08 Dsm Ip Assests B.V. Production of carotenoids in oleaginous yeast and fungi
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US8846374B2 (en) * 2006-12-12 2014-09-30 E I Du Pont De Nemours And Company Carotenoid production in a recombinant oleaginous yeast
MX2009010574A (es) * 2007-04-03 2009-10-22 Du Pont Multienzimas y su uso en la fabricacion de acidos grasos poliinsaturados.
US8957280B2 (en) 2007-05-03 2015-02-17 E. I. Du Pont De Nemours And Company Delta-5 desaturases and their use in making polyunsaturated fatty acids
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CN101970638B (zh) 2007-10-03 2015-02-11 纳幕尔杜邦公司 用于高水平生产二十碳五烯酸的优化解脂耶氏酵母菌株
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US7892792B2 (en) 2008-06-27 2011-02-22 Indian Institute Of Science Cells expressing Pichia cytochrome C
US9394333B2 (en) 2008-12-02 2016-07-19 Wave Life Sciences Japan Method for the synthesis of phosphorus atom modified nucleic acids
WO2010080388A1 (en) 2008-12-18 2010-07-15 E. I. Du Pont De Nemours And Company Reducing byproduction of malonates in a fermentation process
WO2011005761A1 (en) 2009-07-06 2011-01-13 Ontorii, Inc Novel nucleic acid prodrugs and methods use thereof
WO2011109548A2 (en) * 2010-03-02 2011-09-09 Massachusetts Institute Of Technology Microbial engineering for the production of fatty acids and fatty acid derivatives
WO2011133610A1 (en) * 2010-04-22 2011-10-27 E. I. Du Pont De Nemours And Company Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass
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PT2683824T (pt) 2011-03-07 2018-06-07 Dsm Nutritional Products Ag Modificação de microorganismos thraustochytrid
CN107365339A (zh) 2011-07-19 2017-11-21 波涛生命科学有限公司 合成官能化核酸的方法
CN112007045A (zh) 2012-07-13 2020-12-01 波涛生命科学有限公司 手性控制
KR101835401B1 (ko) 2012-07-13 2018-03-08 신 니뽄 바이오메디칼 라보라토리즈, 엘티디. 키랄 핵산 어쥬번트
EP2872485B1 (en) 2012-07-13 2020-12-16 Wave Life Sciences Ltd. Asymmetric auxiliary group
CN102787128A (zh) * 2012-08-28 2012-11-21 江南大学 一种用于多不饱和脂肪酸生物合成的脱饱和酶Δ9 Des
US9005940B2 (en) 2012-12-21 2015-04-14 E I Du Pont De Nemours And Company Down-regulation of a polynucleotide encoding a Sou2 sorbitol utilization protein to modify lipid production in microbial cells
WO2014141098A1 (en) 2013-03-13 2014-09-18 Dsm Nutritional Products Ag Engineering microorganisms
US10322173B2 (en) 2014-01-15 2019-06-18 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent
JPWO2015108047A1 (ja) 2014-01-15 2017-03-23 株式会社新日本科学 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤
EP3095459A4 (en) 2014-01-15 2017-08-23 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having antitumor effect and antitumor agent
BR112016016400A2 (pt) 2014-01-16 2017-10-03 Wave Life Sciences Ltd Composições de oligonucleotídeos quiralmente controlados, seu uso, sua composição farmacêutica, e métodos
CN103834672B (zh) * 2014-03-17 2015-12-09 昆明理工大学 一种δ12-脂肪酸脱氢酶基因及其应用
CN110229832A (zh) * 2019-06-16 2019-09-13 山东理工大学 一种提高耶式解脂酵母生物量和细胞壁产量的菌株和方法
WO2025008447A1 (en) * 2023-07-05 2025-01-09 Bayer Aktiengesellschaft Composition for use in agriculture

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Also Published As

Publication number Publication date
US7749703B2 (en) 2010-07-06
NO20055777D0 (no) 2005-12-06
EP1620561A4 (en) 2006-08-23
US7214491B2 (en) 2007-05-08
WO2004104167A3 (en) 2005-04-28
CA2523786A1 (en) 2004-12-02
WO2004104167A2 (en) 2004-12-02
BRPI0410681A (pt) 2006-06-20
AU2004242095A1 (en) 2004-12-02
EP1620561A2 (en) 2006-02-01
US20060263867A1 (en) 2006-11-23
US20050043527A1 (en) 2005-02-24
US20060263866A1 (en) 2006-11-23

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