NO20054598D0 - Beta-karboliner anvendbare for behandling av betennelsessykdommer - Google Patents

Beta-karboliner anvendbare for behandling av betennelsessykdommer

Info

Publication number: NO20054598D0
Authority: NO; Norway
Prior art keywords: beta; inflammatory diseases; treating inflammatory; carbolines; useful
Prior art date: 2003-04-09

Application number

NO20054598A

Other languages

English (en)

Other versions

NO20054598L (no

Inventor

Hormoz Mazdiyasni

Alfredo Castro

Michael E Hepperle

Julie Fields Liu

Francois Soucy

Yingchun Ye

Robert S Murray

Raman Prakash

Jeremy D Little

Paul E Fleming

Dominic Reynolds

Original Assignee

Millennium Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-04-09

Filing date

2005-10-06

Publication date

2005-10-06

2005-10-06 Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc

2005-10-06 Publication of NO20054598D0 publication Critical patent/NO20054598D0/no

2005-10-27 Publication of NO20054598L publication Critical patent/NO20054598L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Immunology (AREA)
Neurology (AREA)
Oncology (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO20054598A 2003-04-09 2005-10-06 Beta-karboliner anvendbare for behandling av betennelsessykdommer NO20054598L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US46146803P	2003-04-09	2003-04-09
PCT/US2004/011080 WO2004092167A1 (en)	2003-04-09	2004-04-09	Beta-carbolines useful for treating inflammatory disease

Publications (2)

Publication Number	Publication Date
NO20054598D0 true NO20054598D0 (no)	2005-10-06
NO20054598L NO20054598L (no)	2005-10-27

Family

ID=33299818

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20054598A NO20054598L (no)	2003-04-09	2005-10-06	Beta-karboliner anvendbare for behandling av betennelsessykdommer

Country Status (22)

Country	Link
US (2)	US7727985B2 (no)
EP (1)	EP1611134A1 (no)
JP (1)	JP2006522824A (no)
KR (1)	KR20060006031A (no)
CN (1)	CN1802375A (no)
AU (1)	AU2004230952A1 (no)
BR (1)	BRPI0409263A (no)
CA (1)	CA2521300A1 (no)
CO (1)	CO5700746A2 (no)
CR (1)	CR8042A (no)
EA (1)	EA009121B1 (no)
EC (1)	ECSP056145A (no)
HR (1)	HRP20050926A2 (no)
MA (1)	MA27837A1 (no)
MX (1)	MXPA05010793A (no)
NI (1)	NI200500174A (no)
NO (1)	NO20054598L (no)
OA (1)	OA13115A (no)
RS (1)	RS20050832A (no)
TN (1)	TNSN05257A1 (no)
WO (1)	WO2004092167A1 (no)
ZA (1)	ZA200508198B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20060006031A (ko)	2003-04-09	2006-01-18	밀레니엄 파머슈티컬스 인코퍼레이티드	염증 질환 치료에 유용한 베타-카르볼린
JP2007532582A (ja) *	2004-04-09	2007-11-15	ミレニアム・ファーマシューティカルズ・インコーポレイテッド	炎症性疾患の処置に有用なβ−カルボリン
US8119655B2 (en) *	2005-10-07	2012-02-21	Takeda Pharmaceutical Company Limited	Kinase inhibitors
US8518964B2 (en)	2005-11-22	2013-08-27	Merck Sharp & Dohme Corp.	Tricyclic compounds useful as inhibitors of kinases
CA2646316C (en) *	2006-03-15	2016-05-24	Theralogics, Inc.	Methods of treating muscular wasting diseases using nf-kb activation inhibitors
WO2008002246A1 (en) *	2006-06-28	2008-01-03	Astrazeneca Ab	A pharmaceutical composition comprising an ikk2 inhibitor and a second active ingrdient.
BRPI0720032A2 (pt) *	2006-12-13	2013-12-17	Gilead Sciences Inc	Composto e sais farmaceuticamente aceitáveis dos mesmos, processo, formulação de aerossol, método para a prevenção e tratamento de inflamação pulmonar ou broncoconstrição, e, uso de um composto.
US20090137579A1 (en) *	2007-10-23	2009-05-28	Millennium Pharmaceuticals, Inc.	Mesylate salt of an IKK inhibitor
WO2009054965A1 (en) *	2007-10-23	2009-04-30	Millennium Pharmaceuticals, Inc.	Salts of n- (6-chloro-9h-pyrido [3,4-b] ind0l-8-yl) -4- [2- (2, 6-dimethyl-4-morpholinyl) -2-0x0e thyl] -6, 6-dimethyl-morpholinecarboxamide
EP2297347B1 (en)	2008-05-14	2017-03-08	Millennium Pharmaceuticals, Inc.	Methods and kits for monitoring the effects of immunomodulators on adaptive immunity
KR101323448B1 (ko)	2008-10-02	2013-11-27	아사히 가세이 파마 가부시키가이샤	８위 치환 이소퀴놀린 유도체 및 이의 용도
WO2011120911A1 (en)	2010-03-30	2011-10-06	Novartis Ag	Pkc inhibitors for the treatment of b-cell lymphoma having chronic active b-cell-receptor signalling
DK2691394T3 (en) *	2011-03-28	2017-08-28	Sjt Molecular Res S L	RELATIONSHIPS FOR TREATMENT OF METABOLIC SYNDROME
CN102416014B (zh) *	2011-09-13	2012-11-21	河南中医学院	一种生物碱类成分组合物在制备抗甲型h1n1流感病毒药物中的应用
CN102391323B (zh) *	2011-10-18	2013-09-25	首都医科大学	四氢-β-咔啉衍生物、其制备方法及其用途
KR101646916B1 (ko)	2015-07-13	2016-08-09	강원대학교산학협력단	베타-카르볼린 알칼로이드 화합물을 함유하는 염증성 질환의 예방 또는 치료용 조성물
WO2017067670A1 (en)	2015-10-23	2017-04-27	Pharmathen S.A.	A novel process for the preparation of tryptamines and derivatives thereof
CN109593089B (zh) *	2019-01-24	2022-01-28	西南大学	二氮杂螺癸烷哌啶甲酰胺类化合物制备和应用
CN112824387B (zh) *	2019-11-21	2023-03-21	济南尚博生物科技有限公司	一种2-甲基烟酸酯及其制备方法和应用
CN117510494B (zh) *	2023-11-07	2024-04-19	桂林医学院附属医院	β-咔啉-沙利度胺偶联物及其在制备逆转ABT-199耐药的药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR9912944A (pt)	1998-08-12	2001-05-08	Pfizer Prod Inc	Inibidores de tace
DE19951360A1 (de) *	1999-10-26	2001-05-03	Aventis Pharma Gmbh	Substituierte Indole
WO2001068648A1 (en) *	2000-03-15	2001-09-20	Aventis Pharma Deutschland Gmbh	Substituted beta-carbolines with ikb-kinase inhibiting activity
EE200200523A (et) *	2000-03-15	2004-04-15	Aventis Pharma Deutschland Gmbh	Asendatud beeta-karboliinide klassi kuuluv ühend,selle valmistamine ja kasutamine laiaspektrilise ravimi valmistamiseks ning seda sisaldav ravim
BR0212617A (pt) *	2001-09-19	2005-02-09	Pharmacia Corp	Compostos de pirazolila substituìdo para o tratamento de inflamação
WO2003039545A2 (en) *	2001-11-07	2003-05-15	Millennium Pharmaceuticals, Inc.	Carboline derivatives as inhibitors of ikb in the treatment of multiple myeloma and others cancers
EP1606275B1 (en) *	2003-03-07	2008-08-27	Eli Lilly And Company	Opioid receptor antagonists
KR20060006031A (ko)	2003-04-09	2006-01-18	밀레니엄 파머슈티컬스 인코퍼레이티드	염증 질환 치료에 유용한 베타-카르볼린

2004
- 2004-04-09 KR KR1020057019268A patent/KR20060006031A/ko not_active Ceased
- 2004-04-09 CN CNA2004800160170A patent/CN1802375A/zh active Pending
- 2004-04-09 RS YUP-2005/0832A patent/RS20050832A/sr unknown
- 2004-04-09 WO PCT/US2004/011080 patent/WO2004092167A1/en active Application Filing
- 2004-04-09 EA EA200501584A patent/EA009121B1/ru not_active IP Right Cessation
- 2004-04-09 BR BRPI0409263-5A patent/BRPI0409263A/pt not_active IP Right Cessation
- 2004-04-09 MX MXPA05010793A patent/MXPA05010793A/es active IP Right Grant
- 2004-04-09 OA OA1200500279A patent/OA13115A/en unknown
- 2004-04-09 JP JP2006509889A patent/JP2006522824A/ja active Pending
- 2004-04-09 AU AU2004230952A patent/AU2004230952A1/en not_active Abandoned
- 2004-04-09 EP EP04759390A patent/EP1611134A1/en not_active Withdrawn
- 2004-04-09 CA CA002521300A patent/CA2521300A1/en not_active Abandoned
- 2004-04-09 US US10/821,545 patent/US7727985B2/en active Active
2005
- 2005-10-06 NO NO20054598A patent/NO20054598L/no not_active Application Discontinuation
- 2005-10-07 NI NI200500174A patent/NI200500174A/es unknown
- 2005-10-07 TN TNP2005000257A patent/TNSN05257A1/en unknown
- 2005-10-11 ZA ZA200508198A patent/ZA200508198B/xx unknown
- 2005-10-12 CR CR8042A patent/CR8042A/es not_active Application Discontinuation
- 2005-10-25 HR HR20050926A patent/HRP20050926A2/hr not_active Application Discontinuation
- 2005-11-04 CO CO05113041A patent/CO5700746A2/es not_active Application Discontinuation
- 2005-11-07 EC EC2005006145A patent/ECSP056145A/es unknown
- 2005-11-09 MA MA28592A patent/MA27837A1/fr unknown
2009
- 2009-12-17 US US12/640,335 patent/US20100093713A1/en not_active Abandoned

Also Published As

Publication number	Publication date
NO20054598L (no)	2005-10-27
JP2006522824A (ja)	2006-10-05
CN1802375A (zh)	2006-07-12
MXPA05010793A (es)	2005-12-05
OA13115A (en)	2006-11-10
AU2004230952A1 (en)	2004-10-28
EA200501584A1 (ru)	2006-06-30
WO2004092167A8 (en)	2006-01-05
TNSN05257A1 (en)	2007-07-10
EP1611134A1 (en)	2006-01-04
HRP20050926A2 (en)	2006-06-30
KR20060006031A (ko)	2006-01-18
US7727985B2 (en)	2010-06-01
CO5700746A2 (es)	2006-11-30
US20100093713A1 (en)	2010-04-15
RS20050832A (en)	2007-12-31
MA27837A1 (fr)	2006-04-03
BRPI0409263A (pt)	2006-03-28
CR8042A (es)	2006-05-30
ECSP056145A (es)	2006-04-19
NI200500174A (es)	2006-04-17
EA009121B1 (ru)	2007-10-26
ZA200508198B (en)	2007-01-31
US20040235839A1 (en)	2004-11-25
WO2004092167A1 (en)	2004-10-28
CA2521300A1 (en)	2004-10-28

Publication	Publication Date	Title
NO20054598D0 (no)	2005-10-06	Beta-karboliner anvendbare for behandling av betennelsessykdommer
DE602005023172D1 (de)	2010-10-07	Hydantoinderivate zur behandlung von entzündlichen erkrankungen
DE602004023168D1 (de)	2009-10-29	Plattenspeichersteuerwerk
DK1531673T3 (da)	2006-03-06	Hidtil ukendt 2-pyridylethylbenzamidderivat
NO20070753L (no)	2007-05-07	Fremgangsmåte for fremstilling av dihydropteridinoner
CY2014018I2 (el)	2015-12-09	Kαρβαμιδο - υποκατεστημενες πυραζολοπυριδινες
NO20054121D0 (no)	2005-09-05	Benzopyranforbindelser anvendelige for behandling av inflammatoriske tilstander
FI7335U1 (fi)	2006-12-27	Laitteisto lämpöilan modifioimiseksi
NO20055459D0 (no)	2005-11-18	Prosesser
IS8497A (is)	2006-06-02	Aðferðir og hvarfefni til að meðhöndla bólgusjúkdóma
ZA200703125B (en)	2008-09-25	Substituted pteridines for treating inflammatory diseases
EP1611120A4 (en)	2008-04-23	NEW M THODES FOR THE TREATMENT OF INFLAMMATORY DISEASES
DK1487828T3 (da)	2009-02-02	Morpholinyl-urea-derivater til anvendelse til behandling af inflammatoriske sygdomme
DK1597171T3 (da)	2013-02-11	Terapeutisk mikroskum
DK1687297T3 (da)	2014-09-22	Triazindimerer til behandling af autoimmunsygdomme
DE60313502D1 (de)	2007-06-06	180-grad-regler
FI20040180L (fi)	2005-08-07	Koostumus psoriasis-taudin hoitamiseksi
FI20030467A0 (fi)	2003-03-28	Menetelmä tulehdustilojen hoitamiseen
DE602004030793D1 (de)	2011-02-10	Asynchrones flimmerreduktionsverfahren
ATE433983T1 (de)	2009-07-15	Thiadibenzoazulenderivate zur behandlung von entzündlichen erkrankungen
DE602004004308D1 (de)	2007-03-08	Rollstuhl
NO20033160D0 (no)	2003-07-10	Anordning for behandling av gravann
IS8496A (is)	2006-06-02	Samsetningar til meðhöndlunar á fjölgunarsjúkdómum
SE0400037D0 (sv)	2004-01-12	Förfarande för uppförande av hus
FI20031313A0 (fi)	2003-09-15	Ultima

Legal Events

Date	Code	Title	Description
2011-11-28	FC2A	Withdrawal, rejection or dismissal of laid open patent application