[go: up one dir, main page]

NO20052136L - Vaksine mot Hepatitt C-virus (HCV). - Google Patents

Vaksine mot Hepatitt C-virus (HCV).

Info

Publication number
NO20052136L
NO20052136L NO20052136A NO20052136A NO20052136L NO 20052136 L NO20052136 L NO 20052136L NO 20052136 A NO20052136 A NO 20052136A NO 20052136 A NO20052136 A NO 20052136A NO 20052136 L NO20052136 L NO 20052136L
Authority
NO
Norway
Prior art keywords
hcv
hepatitis
virus
present
vaccine
Prior art date
Application number
NO20052136A
Other languages
English (en)
Other versions
NO20052136D0 (no
Inventor
Paul A Hamblin
Sara Brett
Louise Ogilvie
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO20052136D0 publication Critical patent/NO20052136D0/no
Publication of NO20052136L publication Critical patent/NO20052136L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/18—Togaviridae; Flaviviridae
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/89—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection
    • C12N15/895—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection using biolistic methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Sammendrag Foreliggende oppfinnelse angår metoder og preparater anvendelige i behandling og forebygging av hepatitt C-virus (HCV) infeksjoner og symptomer og sykdommer assosiert dermed. Spesielt angår foreliggende oppfinnelse DNA-vaksiner omfattende polynukleotidsekvenser som koder for HCV-proteiner og metoder for behandling av individer infisert med HCV omfattende administrering av vaksinene ifølge foreliggende oppfinnelse.
NO20052136A 2002-11-15 2005-05-02 Vaksine mot Hepatitt C-virus (HCV). NO20052136L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0226722.7A GB0226722D0 (en) 2002-11-15 2002-11-15 Vaccine
PCT/EP2003/012830 WO2004046176A1 (en) 2002-11-15 2003-11-13 Vaccine against hcv

Publications (2)

Publication Number Publication Date
NO20052136D0 NO20052136D0 (no) 2005-05-02
NO20052136L true NO20052136L (no) 2005-07-11

Family

ID=9947928

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20052136A NO20052136L (no) 2002-11-15 2005-05-02 Vaksine mot Hepatitt C-virus (HCV).
NO20052149A NO20052149L (no) 2002-11-15 2005-05-02 Polynukleotidvaksine omfattende sekvens som koder for hepatitt C-virus protein.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20052149A NO20052149L (no) 2002-11-15 2005-05-02 Polynukleotidvaksine omfattende sekvens som koder for hepatitt C-virus protein.

Country Status (21)

Country Link
US (4) US20060135451A1 (no)
EP (2) EP1560844A1 (no)
JP (2) JP2006518331A (no)
KR (2) KR20050085010A (no)
CN (2) CN1738834A (no)
AR (1) AR041964A1 (no)
AU (2) AU2003288072A1 (no)
BR (2) BR0316291A (no)
CA (2) CA2504654A1 (no)
CO (1) CO5700833A2 (no)
GB (1) GB0226722D0 (no)
IS (2) IS7830A (no)
MA (2) MA27700A1 (no)
MX (2) MXPA05005202A (no)
NO (2) NO20052136L (no)
NZ (2) NZ539999A (no)
PL (2) PL376882A1 (no)
RU (2) RU2323744C2 (no)
TW (1) TW200502246A (no)
WO (2) WO2004046176A1 (no)
ZA (2) ZA200503803B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7022830B2 (en) * 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
GB0226722D0 (en) * 2002-11-15 2002-12-24 Glaxo Group Ltd Vaccine
US7439042B2 (en) 2002-12-16 2008-10-21 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis C infection
WO2006044923A2 (en) 2004-10-18 2006-04-27 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis c infection
ES2551113T3 (es) * 2006-01-04 2015-11-16 Glaxosmithkline Biologicals S.A. Proteína E1E2 del VHC adyuvantada con MF59 más vector de alfavirus que codifica E1E2 del VHC para provocar linfocitos T específicos del VHC
US8211444B2 (en) * 2006-03-09 2012-07-03 Transgene S.A. Hepatitis C virus non structural fusion protein
WO2008094197A2 (en) * 2006-07-27 2008-08-07 Ligocyte Pharmaceuticals, Inc. Chimeric influenza virus-like particles
AU2007345682B2 (en) * 2006-07-27 2013-07-18 Ligocyte Pharmaceuticals, Inc. Chimeric virus-like particles
KR100759106B1 (ko) * 2007-02-14 2007-09-19 이화여자대학교 산학협력단 초미세 전기기계 시스템 미러에서 미러 판을 정전 구동부와 결합하는 방법
WO2009022236A2 (en) 2007-08-16 2009-02-19 Tripep Ab Immunogen platform
CA2722423A1 (en) * 2008-04-22 2009-10-29 Rutgers, The State University Hcv e2 construct compositions and methods
US9758794B2 (en) 2008-04-22 2017-09-12 Rutgers, The State University Of New Jersey HCV E2 construct compositions and methods
CA2731842A1 (en) * 2008-07-24 2010-01-28 Aduro Biotech Compositions and methods for the treatment of hepatitis c
EP2331125A4 (en) 2008-09-19 2013-03-27 Globeimmune Inc IMMUNOTHERAPY FOR CHRONIC HEPATITIS C-VIRUS INFECTIONS
CN101748151B (zh) * 2008-12-19 2012-10-17 深圳市源兴生物医药科技有限公司 一种重组人丙肝病毒抗原腺病毒载体及其应用
JP2010168288A (ja) * 2009-01-20 2010-08-05 Yokohama City Univ 最適化した抗原遺伝子の使用によるウイルスワクチンの免疫原性の増強
EP2496609A4 (en) 2009-11-03 2013-05-08 Ligocyte Pharmaceuticals Inc CHIMERIC RSV-F POLYPEPTIDE AND VLPS ON LENTIVIREN OR ALPHA RETROVIRUS GAG BASE
CN102233137B (zh) * 2010-04-30 2013-02-20 北京凯因科技股份有限公司 一种用于治疗乙型肝炎的重组质粒dna疫苗组合物
CN105658790A (zh) 2013-02-21 2016-06-08 东安大略研究所儿童医院有限公司 疫苗组合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6297048B1 (en) * 1992-02-04 2001-10-02 Chiron Corporation Hepatitis therapeutics
CA2202088A1 (en) * 1994-10-05 1996-04-18 Catherine J. Pachuk Hepatitis virus vaccines
IL118364A0 (en) * 1995-05-22 1996-09-12 Bionova Corp A hepatitis C virus-derived composition methods for the preparation thereof and assays for the detection of hepatitis C virus
EP1009763A4 (en) * 1996-06-11 2002-08-07 Merck & Co Inc SYNTHETIC GENES OF HEPATITIS C
US7052696B2 (en) * 1998-07-10 2006-05-30 The United States Of America As Represented By The Department Of Health And Human Services Antigenic epitopes and mosaic polypeptides of hepatitis C virus proteins
AU774887B2 (en) * 1999-07-09 2004-07-08 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Antigenic epitopes and mosaic polypeptides of hepatitis C virus proteins
US6562346B1 (en) * 1999-10-27 2003-05-13 Chiron Corporation Activation of HCV-specific T cells
ATE376558T1 (de) * 1999-11-24 2007-11-15 Novartis Vaccines & Diagnostic Neues nichtstrukturelles hcv polypeptid
FI116851B (fi) * 2001-05-03 2006-03-15 Fit Biotech Oyj Plc Ilmentämisvektori, sen käyttöjä ja menetelmä sen valmistamiseksi sekä sitä sisältäviä tuotteita
GB0226722D0 (en) * 2002-11-15 2002-12-24 Glaxo Group Ltd Vaccine

Also Published As

Publication number Publication date
NO20052149L (no) 2005-07-11
CA2504654A1 (en) 2004-06-03
WO2004046176A1 (en) 2004-06-03
PL376882A1 (pl) 2006-01-09
WO2004046175A1 (en) 2004-06-03
IS7830A (is) 2005-04-28
JP2006518331A (ja) 2006-08-10
NO20052136D0 (no) 2005-05-02
EP1560845A1 (en) 2005-08-10
US20060246090A1 (en) 2006-11-02
MA27700A1 (fr) 2006-01-02
EP1560844A1 (en) 2005-08-10
KR20050085010A (ko) 2005-08-29
KR20050085009A (ko) 2005-08-29
CO5700833A2 (es) 2006-11-30
RU2005113691A (ru) 2006-01-27
AU2003288084A1 (en) 2004-06-15
NZ539999A (en) 2008-03-28
GB0226722D0 (en) 2002-12-24
ZA200503802B (en) 2006-08-30
US20090232847A1 (en) 2009-09-17
NZ539998A (en) 2008-04-30
CA2504715A1 (en) 2004-06-03
CN1738834A (zh) 2006-02-22
RU2323744C2 (ru) 2008-05-10
CN1738833A (zh) 2006-02-22
ZA200503803B (en) 2006-08-30
TW200502246A (en) 2005-01-16
US20060135451A1 (en) 2006-06-22
PL376967A1 (pl) 2006-01-23
AU2003288072A1 (en) 2004-06-15
NO20052149D0 (no) 2005-05-02
AR041964A1 (es) 2005-06-01
US20090104231A1 (en) 2009-04-23
MXPA05005203A (es) 2006-01-27
MA27699A1 (fr) 2006-01-02
RU2005113692A (ru) 2006-01-27
BR0316291A (pt) 2005-10-11
RU2363492C2 (ru) 2009-08-10
IS7831A (is) 2005-04-28
MXPA05005202A (es) 2006-01-27
JP2006524181A (ja) 2006-10-26
BR0316244A (pt) 2005-10-04

Similar Documents

Publication Publication Date Title
NO20052136L (no) Vaksine mot Hepatitt C-virus (HCV).
ATE475423T1 (de) Immunostimulierende polynukleotide sequenzen zur verwendung bei der verhinderung und behandlung von viralen erkrankungen
ATE473750T1 (de) Immunostimulierende polynukleotide sequenzen zur verwendung bei der unterdrückung von hepatitis virus infektion
EA200700243A1 (ru) Способы лечения гепатита с
ATE476983T1 (de) Immunostimulierende polynukleotide sequenzen zur verwendung bei der verhinderung und behandlung von viralen erkrankungen der atemwege
SG156652A1 (en) Yeast-based therapeutic for chronic hepatitis c infection
CY1106334T1 (el) Βελτιστοποιημενου κωδικονιου αλληλουχιες ιου θηλωματος
IS7533A (is) Lifrarbólgu C-veirutálmar
DE60334205D1 (en) Heterocyclische sulfonamid-hepatitis-c-virus-hemmer
EA200900298A1 (ru) Ингибиторы вируса гепатита с
WO2005118626A3 (en) Peptides for inducing a ctl and/or htl response to hepatitis c virus
DE602006015861D1 (de) Antivirale verbindungen
AR045870A1 (es) Terapia de combinacion para la infeccion de virus de hepatitis c
DK1471936T3 (da) HIV-Vaccine og fremgangsmåde til anvendelse
DK1949913T3 (da) Immunstimulatorisk kombination til profylakserne og behandlingen af hepatitis C
RU2010153688A (ru) Режим дозирования телапревира
WO2005028496A3 (en) Vaccine for treatment and prevention of herpes simplex virus infection
MXPA06013388A (es) Vector lentiviral recombinante para la expresion de una proteina flaviviridae y sus aplicaciones como vacuna.
DE60325838D1 (de) Imidazoquinolinamine als adjuvantien für hiv dna vakzine
TW200509964A (en) VP1 of foot-and-mouth disease virus
NO20051561L (no) Nukleinsyremolekyler som koder for humant papillomavirus og anvendelse av disse i vaksine.
MX2007002659A (es) Composicion vacunal contra el virus de la hepatitis c.
WO2004082596A3 (en) Yersinia species compositions
HUP0200162A2 (hu) Haemophilus somnus transzferrin-kötő fehérjék klónozása és expresszálása
ATE544453T1 (de) Kombinationstherapien mit l-fmau zur behandlung von hepatitis-b-virus-infektionen

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application