NO20035399L - Pyrrolidinoksadiazol- og tiadiazolderivater - Google Patents

Pyrrolidinoksadiazol- og tiadiazolderivater

Info

Publication number: NO20035399L
Authority: NO; Norway
Prior art keywords: thiadiazole derivatives; pyrrolidine oxadiazole; oxadiazole; pyrrolidine; thiadiazole
Prior art date: 2001-06-18

Application number

NO20035399A

Other languages

English (en)

Other versions

NO20035399D0 (no

Inventor

Matthias Schwarz

Russel J Thomas

Anna Quattorpani

Patrick Page

Vincent Pomel

Original Assignee

Applied Research Systems

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-18

Filing date

2003-12-04

Publication date

2004-02-17

2003-12-04 Application filed by Applied Research Systems filed Critical Applied Research Systems

2003-12-04 Publication of NO20035399D0 publication Critical patent/NO20035399D0/no

2004-02-17 Publication of NO20035399L publication Critical patent/NO20035399L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

NO20035399A 2001-06-18 2003-12-04 Pyrrolidinoksadiazol- og tiadiazolderivater NO20035399L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01113632		2001-06-18
PCT/EP2002/006629 WO2002102799A2 (en)	2001-06-18	2002-06-14	Pyrrolidine oxadiazole- and thiadiazole oxime derivatives being oxytocin receptor antagonists

Publications (2)

Publication Number	Publication Date
NO20035399D0 NO20035399D0 (no)	2003-12-04
NO20035399L true NO20035399L (no)	2004-02-17

Family

ID=8177641

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20035399A NO20035399L (no)	2001-06-18	2003-12-04	Pyrrolidinoksadiazol- og tiadiazolderivater

Country Status (27)

Country	Link
US (2)	US7115639B2 (no)
EP (1)	EP1444225B1 (no)
JP (1)	JP4426284B2 (no)
KR (1)	KR20040030678A (no)
CN (1)	CN100564378C (no)
AR (1)	AR036108A1 (no)
AU (1)	AU2002319237B2 (no)
BG (1)	BG108424A (no)
BR (1)	BR0211030A (no)
CA (1)	CA2449578C (no)
CZ (1)	CZ20033475A3 (no)
EA (1)	EA006212B1 (no)
EE (1)	EE200400022A (no)
ES (1)	ES2397305T3 (no)
HK (1)	HK1074204A1 (no)
HR (1)	HRP20031017A2 (no)
HU (1)	HUP0400238A2 (no)
IL (1)	IL159219A0 (no)
MX (1)	MXPA03011441A (no)
MY (1)	MY128890A (no)
NO (1)	NO20035399L (no)
PL (1)	PL367275A1 (no)
RS (1)	RS99503A (no)
SK (1)	SK15552003A3 (no)
UA (1)	UA75145C2 (no)
WO (1)	WO2002102799A2 (no)
ZA (1)	ZA200309402B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2002319237B2 (en)	2001-06-18	2008-01-03	Merck Serono Sa	Pyrrolidine oxadiazole- and thiadiazole oxime derivatives being oxytocin receptor antagonists
CA2515546C (en)	2003-02-27	2011-11-22	Applied Research Systems Ars Holding N.V.	Pyrrolidine derivatives as oxytocin antagonists
DK1725526T3 (da) *	2004-02-26	2008-03-03	Serono Lab	Fremgangsmåde til fremstilling af pyrrolidinoximer
BR122020016659B8 (pt)	2005-05-10	2021-07-27	Incyte Holdings Corp	moduladores de 2,3-dioxigenase de indolamina e métodos de modulação de atividade de inibição e de imunossupressão
JP5294874B2 (ja)	2005-12-20	2013-09-18	インサイト・コーポレイション	インドールアミン２，３−ジオキシゲナーゼのモジュレーターとしてのｎ−ヒドロキシアミジノヘテロ環
ES2444574T3 (es)	2006-09-19	2014-02-25	Incyte Corporation	N-hidroxiamidinoheterociclos como moduladores de la indolamina 2,3-dioxigenasa
CL2007002650A1 (es)	2006-09-19	2008-02-08	Incyte Corp	Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
LT2824100T (lt)	2008-07-08	2018-05-10	Incyte Holdings Corporation	1,2,5-oksadiazolai, kaip indolamino 2,3-dioksigenazės inhibitoriai
EP2845850A1 (en)	2013-09-10	2015-03-11	ObsEva S.A.	Pyrrolidine derivatives as oxytocin/vasopressin V1a receptors antagonists
LT3066085T (lt)	2013-11-08	2020-06-25	Incyte Holdings Corporation	Indolamino 2,3-dioksigenazės inhibitoriaus sintezės būdas
EP2886107A1 (en)	2013-12-17	2015-06-24	ObsEva S.A.	Oral formulations of pyrrolydine derivatives
CN106795110A (zh)	2014-07-02	2017-05-31	奥布赛瓦股份公司	治疗ot‑r活性相关的病症的方法中可用的晶体(3z，5s)‑5‑(羟甲基)‑1‑[(2’‑甲基‑1，1’‑联苯‑4‑基)羰基]吡咯烷‑3‑酮o‑甲基肟

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2722190B1 (fr) *	1994-07-05	1996-10-04	Sanofi Sa	Derives de 1-benzyl-1,3-dihydro-2h-benzimidazol-2-one, leur preparation, les compositions pharmaceutique en contenant
CA2210138A1 (en)	1995-01-24	1996-08-01	Peter D. Williams	Tocolytic oxytocin receptor antagonists
US5756497A (en)	1996-03-01	1998-05-26	Merck & Co., Inc.	Tocolytic oxytocin receptor antagonists
FR2757157B1 (fr) *	1996-12-13	1999-12-31	Sanofi Sa	Derives d'indolin-2-one, procede pour leur preparation et compositions pharmaceutiques les contenant
DE60026514T2 (de)	1999-05-05	2006-11-09	Merck & Co., Inc.	Neue prolinverbindungen als mikrobizide mittel
ES2262640T3 (es)	2000-03-27	2006-12-01	Applied Research Systems Ars Holding N.V.	Derivados de pirrolidina farmaceuticamente activos como inhibidores de bax.
DK1268419T3 (da) *	2000-03-27	2006-10-02	Applied Research Systems	Farmaceutisk aktive pyrrolidinderivater som BAX-inhibitorer
WO2002032864A1 (en) *	2000-10-17	2002-04-25	Applied Research Systems Ars Holding N.V.	Pharmaceutically active sulfanilide derivatives
JP4350948B2 (ja) *	2001-03-20	2009-10-28	ラボラトワールセローノソシエテアノニム	オキシトシン調節活性を有するピロリジンエステル誘導体
AU2002319237B2 (en)	2001-06-18	2008-01-03	Merck Serono Sa	Pyrrolidine oxadiazole- and thiadiazole oxime derivatives being oxytocin receptor antagonists
DE60207755T2 (de) *	2001-12-20	2006-07-27	Applied Research Systems Ars Holding N.V.	Triazole als oxytocin-antagonisten
UA78058C2 (en) *	2002-07-05	2007-02-15	Applied Research Systems	Pyrrolidine derivative as oxitocin antagonists

2002
- 2002-06-14 AU AU2002319237A patent/AU2002319237B2/en not_active Ceased
- 2002-06-14 EP EP02748785A patent/EP1444225B1/en not_active Expired - Lifetime
- 2002-06-14 US US10/480,992 patent/US7115639B2/en not_active Expired - Fee Related
- 2002-06-14 RS YU99503A patent/RS99503A/sr unknown
- 2002-06-14 CN CNB028159446A patent/CN100564378C/zh not_active Expired - Fee Related
- 2002-06-14 SK SK1555-2003A patent/SK15552003A3/sk not_active Application Discontinuation
- 2002-06-14 UA UA20031211897A patent/UA75145C2/uk unknown
- 2002-06-14 ES ES02748785T patent/ES2397305T3/es not_active Expired - Lifetime
- 2002-06-14 EE EEP200400022A patent/EE200400022A/xx unknown
- 2002-06-14 PL PL02367275A patent/PL367275A1/xx not_active Application Discontinuation
- 2002-06-14 CA CA2449578A patent/CA2449578C/en not_active Expired - Fee Related
- 2002-06-14 MX MXPA03011441A patent/MXPA03011441A/es active IP Right Grant
- 2002-06-14 JP JP2003506272A patent/JP4426284B2/ja not_active Expired - Fee Related
- 2002-06-14 WO PCT/EP2002/006629 patent/WO2002102799A2/en not_active Application Discontinuation
- 2002-06-14 KR KR10-2003-7016485A patent/KR20040030678A/ko not_active Application Discontinuation
- 2002-06-14 HU HU0400238A patent/HUP0400238A2/hu unknown
- 2002-06-14 EA EA200400049A patent/EA006212B1/ru not_active IP Right Cessation
- 2002-06-14 IL IL15921902A patent/IL159219A0/xx unknown
- 2002-06-14 BR BR0211030-0A patent/BR0211030A/pt not_active IP Right Cessation
- 2002-06-14 CZ CZ20033475A patent/CZ20033475A3/cs unknown
- 2002-06-18 MY MYPI20022260A patent/MY128890A/en unknown
- 2002-06-21 AR ARP020102353A patent/AR036108A1/es unknown
2003
- 2003-12-03 ZA ZA200309402A patent/ZA200309402B/en unknown
- 2003-12-04 NO NO20035399A patent/NO20035399L/no unknown
- 2003-12-08 BG BG108424A patent/BG108424A/xx unknown
- 2003-12-08 HR HR20031017A patent/HRP20031017A2/xx not_active Application Discontinuation
2005
- 2005-09-16 HK HK05108106.9A patent/HK1074204A1/xx not_active IP Right Cessation
2006
- 2006-06-09 US US11/449,802 patent/US20060229343A1/en not_active Abandoned

Also Published As

Publication number	Publication date
IL159219A0 (en)	2004-06-01
CA2449578A1 (en)	2002-12-27
ES2397305T3 (es)	2013-03-06
WO2002102799A2 (en)	2002-12-27
MXPA03011441A (es)	2004-07-01
AR036108A1 (es)	2004-08-11
JP4426284B2 (ja)	2010-03-03
EA200400049A1 (ru)	2004-08-26
HK1074204A1 (en)	2005-11-04
HRP20031017A2 (en)	2004-04-30
RS99503A (en)	2006-12-15
US20040220238A1 (en)	2004-11-04
BR0211030A (pt)	2004-06-22
EP1444225A2 (en)	2004-08-11
NO20035399D0 (no)	2003-12-04
KR20040030678A (ko)	2004-04-09
CA2449578C (en)	2011-12-13
BG108424A (en)	2005-03-31
US20060229343A1 (en)	2006-10-12
WO2002102799A3 (en)	2003-04-03
MY128890A (en)	2007-02-28
CN100564378C (zh)	2009-12-02
EA006212B1 (ru)	2005-10-27
JP2004534804A (ja)	2004-11-18
US7115639B2 (en)	2006-10-03
SK15552003A3 (sk)	2004-05-04
EE200400022A (et)	2004-04-15
CZ20033475A3 (en)	2004-05-12
AU2002319237B2 (en)	2008-01-03
UA75145C2 (en)	2006-03-15
PL367275A1 (en)	2005-02-21
EP1444225B1 (en)	2012-10-10
ZA200309402B (en)	2004-12-03
CN1639155A (zh)	2005-07-13
HUP0400238A2 (hu)	2004-07-28

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NO20040469L (no)	2004-04-30	Heterocykliske forbindelser samt fremstilling og anvendelse derav
IS6385A (is)	2002-05-15	Ný notkun og nýjar N-asabísýkló-amíð afleiður
DK1400518T3 (da)	2007-03-26	Heterocycliske forbindelser og lægemidler
CY2016002I1 (el)	2016-10-05	Ν-υποκατεστημενο καρβαμουλοξυαλκυλιο - παραγωγα αζολιου
DE50112013D1 (de)	2007-03-22	Deodorantien und antiperspirantien
DK1292604T3 (da)	2009-06-15	2-Aminocarbonyl-9H-purinderivater
ATE319451T1 (de)	2006-03-15	Tetrahydrochinolin-derivate
ATE312827T1 (de)	2005-12-15	3-substituierte-4-pyrimidonderivate
AR028343A1 (es)	2003-05-07	Derivados de pirrolidina y piperidina
ATE288437T1 (de)	2005-02-15	Tetrahydro-heterocycloazepinyl-pyrimidin-deriva e
IS6759A (is)	2003-03-27	Ný þíadíasól og oxadíasól og notkun þeirra sem fosfórdíesterasa-7 hindra
ATE298332T1 (de)	2005-07-15	Decahydro-isochinolinderivate
DK1280809T3 (da)	2005-11-07	Antitumorecteinascidinderivater
ATE297920T1 (de)	2005-07-15	Linezolid-krystall form ii
DK1226131T3 (da)	2004-04-19	Isoxazolcarboxamidderivater
NO20035399D0 (no)	2003-12-04	Pyrrolidinoksadiazol- og tiadiazolderivater
ZA200309513B (en)	2004-12-08	Novel heterocyclic derivatives and medicinal use thereof.
DE60223031D1 (de)	2007-11-29	Arylpiperazin gebundene tetrahydroindolonderivate
DE60032898D1 (de)	2007-02-22	Arylthiazolidindion- und aryloxazolidinderivate
DK1322593T3 (da)	2004-10-11	O-substituerede-6-methyl-tramadol-derivater
EP1392317A4 (en)	2005-10-19	SUBSTITUTED 1-BENZAZEPINE AND DERIVATIVES THEREOF
DE60117096D1 (de)	2006-04-20	Dihydroindol- und tetrahydrochinolinderivate
DK1246791T3 (da)	2005-02-14	Aminomethyl-phenyl-cyklohexanonderivater
DK1392670T3 (da)	2005-08-08	Substituerede C-furan-2-yl-methylamin- og C-thiophen-2-yl-methylamin-derivater
IS6468A (is)	2002-07-11	Heterósýklískar amíð afleiður