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NO20030298L - Nye heteroarylderivater og deres anvendelse som farmasöytiske midler - Google Patents

Nye heteroarylderivater og deres anvendelse som farmasöytiske midler

Info

Publication number
NO20030298L
NO20030298L NO20030298A NO20030298A NO20030298L NO 20030298 L NO20030298 L NO 20030298L NO 20030298 A NO20030298 A NO 20030298A NO 20030298 A NO20030298 A NO 20030298A NO 20030298 L NO20030298 L NO 20030298L
Authority
NO
Norway
Prior art keywords
pharmaceutical agents
heteroaryl derivatives
novel heteroaryl
novel
derivatives
Prior art date
Application number
NO20030298A
Other languages
English (en)
Other versions
NO20030298D0 (no
Inventor
Peter Emig
Eckard Guenter
Juergen Schmidt
Bernd Nickel
Bernhard Kutscher
Original Assignee
Zentaris Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Ag filed Critical Zentaris Ag
Publication of NO20030298L publication Critical patent/NO20030298L/no
Publication of NO20030298D0 publication Critical patent/NO20030298D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20030298A 2000-07-21 2003-01-20 Nye heteroarylderivater og deres anvendelse som farmasöytiske midler NO20030298D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10035928A DE10035928A1 (de) 2000-07-21 2000-07-21 Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
PCT/EP2001/008261 WO2002008192A1 (de) 2000-07-21 2001-07-18 Neue heteroaryl-derivate und deren verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
NO20030298L true NO20030298L (no) 2003-01-20
NO20030298D0 NO20030298D0 (no) 2003-01-20

Family

ID=7649980

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030298A NO20030298D0 (no) 2000-07-21 2003-01-20 Nye heteroarylderivater og deres anvendelse som farmasöytiske midler

Country Status (23)

Country Link
US (5) US6890926B2 (no)
EP (1) EP1305290A1 (no)
JP (1) JP2004504381A (no)
KR (1) KR20030022287A (no)
CN (1) CN1443171A (no)
AR (1) AR033678A1 (no)
AU (2) AU7975701A (no)
BG (1) BG107508A (no)
BR (1) BR0112589A (no)
CA (1) CA2353369A1 (no)
CZ (1) CZ2003415A3 (no)
DE (1) DE10035928A1 (no)
HU (1) HUP0300838A2 (no)
IL (1) IL153361A0 (no)
MX (1) MXPA02012565A (no)
NO (1) NO20030298D0 (no)
NZ (1) NZ524154A (no)
PL (1) PL358788A1 (no)
RU (1) RU2265602C2 (no)
SK (1) SK1842003A3 (no)
TW (1) TWI228505B (no)
WO (1) WO2002008192A1 (no)
ZA (1) ZA200210180B (no)

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CN1668604A (zh) * 2002-07-17 2005-09-14 赞塔里斯有限公司 新颖的蒽衍生物及其作为药物的用途
JP2006516656A (ja) * 2003-01-28 2006-07-06 アヴェンティス ファーマ エス．エー． Ｎ−アリールヘテロ芳香族物質、それを含む組成物およびその用途
FR2855825B1 (fr) * 2003-06-04 2008-08-22 Aventis Pharma Sa Produits aryl-heteroaromatiques, compositions les contenant et utilisation
PE20050226A1 (es) * 2003-06-04 2005-05-18 Aventis Pharma Sa Productos aril-heteroaromaticos y composiciones que los contienen
JP2007519639A (ja) * 2004-01-08 2007-07-19 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト 複素環アリル誘導体
DE102004003428A1 (de) * 2004-01-23 2005-08-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Beta-2-Agonisten, und deren Verwendung als Arzneimittel
FR2871157A1 (fr) * 2004-06-04 2005-12-09 Aventis Pharma Sa Produits biaryl aromatiques, compositions les contenant et utilisation
CN1830964B (zh) * 2005-03-11 2011-06-15 中国科学院上海药物研究所 4-取代苯氨基-3-硝基喹啉类化合物及其制备方法和用途
US8835426B2 (en) * 2007-02-26 2014-09-16 Vitae Pharmaceuticals, Inc. Cyclic urea and carbamate inhibitors of 11β-hydroxysteroid dehydrogenase 1
JP5451611B2 (ja) * 2007-07-26 2014-03-26 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックインヒビター
AR069207A1 (es) * 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
JP5490014B2 (ja) 2007-12-11 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤
TW200934490A (en) * 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) * 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
CA2714532A1 (en) * 2008-02-11 2009-08-20 Vitae Pharmaceuticals, Inc. 1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
EP2254872A2 (en) * 2008-02-15 2010-12-01 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
EP2274287B1 (en) * 2008-03-18 2016-03-09 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
CA2723039A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8242111B2 (en) * 2008-05-01 2012-08-14 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
EP2291370B1 (en) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
DK2300461T3 (da) * 2008-05-01 2013-06-03 Vitae Pharmaceuticals Inc Cycliske inhibitorer af 11beta-hydroxysteroid-dehydrogenase 1
TW201016691A (en) 2008-07-25 2010-05-01 Boehringer Ingelheim Int Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
DK2324018T3 (da) 2008-07-25 2013-10-14 Boehringer Ingelheim Int Cykliske inhibitorer af 11 beta-hydroxysteroid dehydrogenase 1
US8637505B2 (en) 2009-02-04 2014-01-28 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW201039034A (en) * 2009-04-27 2010-11-01 Chunghwa Picture Tubes Ltd Pixel structure and the method of forming the same
UA109255C2 (ru) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
GEP20156309B (en) * 2009-04-30 2015-07-10 Vitae Pharmaceuticals Inc Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
US8883778B2 (en) 2009-07-01 2014-11-11 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
WO2011159760A1 (en) 2010-06-16 2011-12-22 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
EP2585444B1 (en) 2010-06-25 2014-10-22 Boehringer Ingelheim International GmbH Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders
AU2011325286B2 (en) 2010-11-02 2015-04-16 Boehringer Ingelheim International Gmbh Pharmaceutical combinations for the treatment of metabolic disorders
CN109641884B (zh) * 2016-08-18 2024-01-02 维达克制药有限公司 哌嗪衍生物、其药物组合物及其使用方法

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US4656174A (en) * 1982-07-24 1987-04-07 Pfizer Inc. Quinoline therapeutic agents
FR2538388B1 (fr) 1982-12-24 1985-06-21 Pharmuka Lab Nouveaux derives de naphtalene- ou azanaphtalenecarboxamide, leurs procedes de preparation et leur utilisation comme medicaments
EP0318235A3 (en) * 1987-11-25 1991-05-02 Takeda Chemical Industries, Ltd. Paf antagonist, 1,4-disubstituted piperazine compounds and production thereof
CZ280532B6 (cs) 1990-10-10 1996-02-14 Schering Corporation Pyridinové a pyridin-N-oxidové deriváty diaryl-methyl-piperidinů nebo piperazinů, jejich použití a způsob jejich přípravy, farmaceutický prostředek je obsahující
US5736539A (en) * 1993-06-18 1998-04-07 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
BR9709015A (pt) * 1996-05-20 1999-08-03 Darwin Discovery Ltd Quinolina carboxamidas como inbidores de tnf e como inbidores de pde-iv
WO1997044329A1 (en) 1996-05-20 1997-11-27 Teijin Limited Diarylalkyl cyclic diamine derivatives as chemokine receptor antagonists
AU713171B2 (en) * 1996-06-29 1999-11-25 Samjin Pharmaceutical Co., Ltd. Piperazine derivatives and process for the preparation thereof
US5861395A (en) 1996-09-13 1999-01-19 Schering Corporation Compounds useful for inhibition of farnesyl proteins transferase
FR2753706B1 (fr) 1996-09-20 1998-10-30 Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant
PT957100E (pt) * 1997-07-07 2005-02-28 Kowa Co Derivados de diamina e farmaceuticos que os contem
DE19743435A1 (de) 1997-10-01 1999-04-08 Merck Patent Gmbh Benzamidinderivate
BR9913654A (pt) * 1998-08-28 2001-11-27 Scios Inc Inibidores de p-38alfa quinase
CA2362495A1 (en) 1999-03-03 2000-09-08 Theresa M. Williams Inhibitors of prenyl-protein transferases
DE10035927A1 (de) * 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
US6610274B1 (en) * 2000-12-22 2003-08-26 Wallace J. Gardner Anti-inflammatory composition comprising tetracycline

Also Published As

Publication number Publication date
AR033678A1 (es) 2004-01-07
IL153361A0 (en) 2003-07-06
CN1443171A (zh) 2003-09-17
US20050176744A1 (en) 2005-08-11
CA2353369A1 (en) 2002-01-21
JP2004504381A (ja) 2004-02-12
NZ524154A (en) 2005-02-25
RU2265602C2 (ru) 2005-12-10
CZ2003415A3 (cs) 2004-05-12
US20050245523A1 (en) 2005-11-03
HUP0300838A2 (hu) 2003-07-28
TWI228505B (en) 2005-03-01
US20040132747A1 (en) 2004-07-08
PL358788A1 (en) 2004-08-23
EP1305290A1 (de) 2003-05-02
KR20030022287A (ko) 2003-03-15
BG107508A (bg) 2003-09-30
AU7975701A (en) 2002-02-05
US6890926B2 (en) 2005-05-10
US20020103214A1 (en) 2002-08-01
SK1842003A3 (en) 2004-10-05
US7026310B2 (en) 2006-04-11
MXPA02012565A (es) 2003-09-22
NO20030298D0 (no) 2003-01-20
WO2002008192A1 (de) 2002-01-31
US20040097530A1 (en) 2004-05-20
BR0112589A (pt) 2003-05-20
US7056912B2 (en) 2006-06-06
AU2001279757B2 (en) 2005-05-26
US6936615B2 (en) 2005-08-30
ZA200210180B (en) 2003-02-12
DE10035928A1 (de) 2002-03-07

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