NO20025791D0 - Fremgangsmåte for fluormetylering av alkoholer via halogenativ dekarboksylering - Google Patents
Fremgangsmåte for fluormetylering av alkoholer via halogenativ dekarboksyleringInfo
- Publication number
- NO20025791D0 NO20025791D0 NO20025791A NO20025791A NO20025791D0 NO 20025791 D0 NO20025791 D0 NO 20025791D0 NO 20025791 A NO20025791 A NO 20025791A NO 20025791 A NO20025791 A NO 20025791A NO 20025791 D0 NO20025791 D0 NO 20025791D0
- Authority
- NO
- Norway
- Prior art keywords
- formula
- group
- alpha
- fluoromethylation
- hydrogen
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000006114 decarboxylation reaction Methods 0.000 title abstract 2
- 238000005799 fluoromethylation reaction Methods 0.000 title abstract 2
- 150000001298 alcohols Chemical class 0.000 title 1
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 150000001805 chlorine compounds Chemical class 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000012320 chlorinating reagent Substances 0.000 abstract 1
- -1 fluoride compound Chemical class 0.000 abstract 1
- 239000012025 fluorinating agent Substances 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- JEHCHYAKAXDFKV-UHFFFAOYSA-J lead tetraacetate Chemical compound CC(=O)O[Pb](OC(C)=O)(OC(C)=O)OC(C)=O JEHCHYAKAXDFKV-UHFFFAOYSA-J 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/587,417 US6271422B1 (en) | 2000-06-01 | 2000-06-01 | Method for fluoromethylation of alcohols via halogenative decarboxylation |
PCT/US2001/015516 WO2001094286A1 (en) | 2000-06-01 | 2001-05-14 | Method for fluoromethylation of alcohols via halogenative decarboxylation |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20025791L NO20025791L (no) | 2002-12-02 |
NO20025791D0 true NO20025791D0 (no) | 2002-12-02 |
Family
ID=24349720
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20025791A NO20025791D0 (no) | 2000-06-01 | 2002-12-02 | Fremgangsmåte for fluormetylering av alkoholer via halogenativ dekarboksylering |
Country Status (29)
Country | Link |
---|---|
US (1) | US6271422B1 (de) |
EP (1) | EP1286939B1 (de) |
JP (1) | JP2004508293A (de) |
KR (1) | KR100799895B1 (de) |
CN (1) | CN1283606C (de) |
AR (1) | AR028664A1 (de) |
AT (1) | ATE317839T1 (de) |
AU (2) | AU2001261565B2 (de) |
BG (1) | BG107336A (de) |
BR (1) | BR0110776A (de) |
CA (1) | CA2410428A1 (de) |
CZ (1) | CZ20023790A3 (de) |
DE (1) | DE60117258T2 (de) |
DK (1) | DK1286939T3 (de) |
ES (1) | ES2258085T3 (de) |
HK (1) | HK1054371B (de) |
HU (1) | HUP0302239A3 (de) |
IL (2) | IL152857A0 (de) |
MX (1) | MXPA02011851A (de) |
NO (1) | NO20025791D0 (de) |
NZ (1) | NZ522502A (de) |
PE (1) | PE20011339A1 (de) |
PL (1) | PL364001A1 (de) |
PT (1) | PT1286939E (de) |
SK (1) | SK17512002A3 (de) |
TW (1) | TWI222435B (de) |
UY (1) | UY26738A1 (de) |
WO (1) | WO2001094286A1 (de) |
ZA (1) | ZA200208850B (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7083580B2 (en) | 2001-04-06 | 2006-08-01 | Mattioli Engineering Ltd. | Method and apparatus for skin absorption enhancement and transdermal drug delivery |
ES2289524T3 (es) * | 2003-09-10 | 2008-02-01 | Cristalia Produtos Quimicos Farmaceuticos Ltda. | Composicion farmaceutica estable de un compuesto de fluoroeter para uso anestesico, procedimiento para estabilizar un compuesto de fluoroeter, uso de un agente estabilizador para evitar la degradacion de un compuesto de fluoroeter. |
ES2402145T3 (es) * | 2004-11-17 | 2013-04-29 | Piramal Critical Care, Inc. | Procedimiento para la preparación de sevoflurano |
CN103664584B (zh) * | 2013-12-23 | 2015-06-03 | 湖南方盛制药股份有限公司 | a-氟代丙酰乙酸酯的制备方法 |
CN104529721B (zh) * | 2015-01-16 | 2017-04-19 | 河北一品制药有限公司 | 一种七氟烷的工业化制备方法 |
CN107698430B (zh) * | 2017-11-01 | 2021-01-08 | 华东医药(西安)博华制药有限公司 | 一种七氟烷反应液的后处理方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL32586A (en) * | 1968-10-28 | 1973-11-28 | Baxter Laboratories Inc | 1,3-polyhalo-2-propyl methyl and halomethyl ethers and their preparation |
US3683092A (en) | 1970-07-31 | 1972-08-08 | Baxter Laboratories Inc | Method of anesthesia |
US4469898A (en) | 1979-12-26 | 1984-09-04 | Baxter Travenol Laboratories, Inc. | Method of synthesizing fluoromethylhexafluoroisopropyl ether |
US4314087A (en) | 1979-12-26 | 1982-02-02 | Baxter Travenol Laboratories, Inc. | Methods of synthesizing hexafluoroisopropanol from impure mixtures and synthesis of a fluoromethyl ether therefrom |
US4250334A (en) | 1979-12-26 | 1981-02-10 | Baxter Travenol Laboratories, Inc. | Method of synthesizing fluoromethylhexafluoroisopropyl ether |
JPS57209235A (en) * | 1981-06-18 | 1982-12-22 | Sumitomo Chem Co Ltd | Tetrahydronaphthalene derivative and its preparation |
US4847427A (en) * | 1988-04-13 | 1989-07-11 | E. I. Du Pont De Nemours And Company | Process for preparing fluorocarbon polyethers |
US4874901A (en) | 1988-05-06 | 1989-10-17 | Boc, Inc. | Process for the production of polyfluorinated ethers |
US4996371A (en) * | 1990-01-16 | 1991-02-26 | Boc, Inc. | Method for fluorodecarboxylation |
EP0822172B2 (de) * | 1996-02-21 | 2004-10-06 | Central Glass Company, Limited | Verfahren zur herstellung von fluoromethyl-(1,1,1,3,3,3)-hexafluoroisopropylether |
US5789630A (en) | 1996-02-27 | 1998-08-04 | University Of Iowa Research Foundation | Process for the synthesis of hexafluoropropanes |
US5705710A (en) | 1997-01-15 | 1998-01-06 | University Of Iowa Research Foundation | Process for the synthesis of hexafluoroisopropyl ethers |
US5969193A (en) * | 1997-08-18 | 1999-10-19 | Medeva Pharmaceuticals Pa, Inc. | Method for the preparation of sevoflurane |
US5886239A (en) * | 1997-11-21 | 1999-03-23 | Baxter International Inc. | Method of preparing monofluoromethyl ethers |
US6100434A (en) * | 1999-03-26 | 2000-08-08 | Abbott Laboratories | Method for synthesizing sevoflurane and an intermediate thereof |
US6245949B1 (en) * | 2000-06-01 | 2001-06-12 | Abbott Laboratories | Synthetic method for the fluoromethylation of alcohols |
US6303831B1 (en) * | 2000-06-01 | 2001-10-16 | Abbott Laboratories | Synthetic method for fluoromethylation of halogenated alcohols |
-
2000
- 2000-06-01 US US09/587,417 patent/US6271422B1/en not_active Expired - Lifetime
-
2001
- 2001-05-14 CN CNB018104053A patent/CN1283606C/zh not_active Expired - Fee Related
- 2001-05-14 DE DE60117258T patent/DE60117258T2/de not_active Expired - Fee Related
- 2001-05-14 JP JP2002501804A patent/JP2004508293A/ja not_active Ceased
- 2001-05-14 AT AT01935471T patent/ATE317839T1/de not_active IP Right Cessation
- 2001-05-14 ES ES01935471T patent/ES2258085T3/es not_active Expired - Lifetime
- 2001-05-14 PT PT01935471T patent/PT1286939E/pt unknown
- 2001-05-14 MX MXPA02011851A patent/MXPA02011851A/es active IP Right Grant
- 2001-05-14 KR KR1020027016188A patent/KR100799895B1/ko not_active Expired - Fee Related
- 2001-05-14 HK HK03105010.2A patent/HK1054371B/en not_active IP Right Cessation
- 2001-05-14 IL IL15285701A patent/IL152857A0/xx unknown
- 2001-05-14 AU AU2001261565A patent/AU2001261565B2/en not_active Ceased
- 2001-05-14 HU HU0302239A patent/HUP0302239A3/hu unknown
- 2001-05-14 DK DK01935471T patent/DK1286939T3/da active
- 2001-05-14 NZ NZ522502A patent/NZ522502A/en unknown
- 2001-05-14 AU AU6156501A patent/AU6156501A/xx active Pending
- 2001-05-14 WO PCT/US2001/015516 patent/WO2001094286A1/en active IP Right Grant
- 2001-05-14 CA CA002410428A patent/CA2410428A1/en not_active Abandoned
- 2001-05-14 BR BR0110776-3A patent/BR0110776A/pt not_active IP Right Cessation
- 2001-05-14 PL PL01364001A patent/PL364001A1/xx not_active IP Right Cessation
- 2001-05-14 EP EP01935471A patent/EP1286939B1/de not_active Expired - Lifetime
- 2001-05-14 CZ CZ20023790A patent/CZ20023790A3/cs unknown
- 2001-05-14 SK SK1751-2002A patent/SK17512002A3/sk unknown
- 2001-05-31 AR ARP010102630A patent/AR028664A1/es unknown
- 2001-05-31 UY UY26738A patent/UY26738A1/es not_active Application Discontinuation
- 2001-06-01 TW TW090113351A patent/TWI222435B/zh not_active IP Right Cessation
- 2001-06-01 PE PE2001000507A patent/PE20011339A1/es not_active Application Discontinuation
-
2002
- 2002-10-31 ZA ZA200208850A patent/ZA200208850B/en unknown
- 2002-11-14 IL IL152857A patent/IL152857A/en not_active IP Right Cessation
- 2002-11-28 BG BG107336A patent/BG107336A/bg unknown
- 2002-12-02 NO NO20025791A patent/NO20025791D0/no not_active Application Discontinuation
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |