[go: up one dir, main page]

NO20022948L - Partially saturated calcium channel blocking compounds - Google Patents

Partially saturated calcium channel blocking compounds

Info

Publication number
NO20022948L
NO20022948L NO20022948A NO20022948A NO20022948L NO 20022948 L NO20022948 L NO 20022948L NO 20022948 A NO20022948 A NO 20022948A NO 20022948 A NO20022948 A NO 20022948A NO 20022948 L NO20022948 L NO 20022948L
Authority
NO
Norway
Prior art keywords
calcium channel
partially saturated
channel blocking
saturated calcium
blocking compounds
Prior art date
Application number
NO20022948A
Other languages
Norwegian (no)
Other versions
NO20022948D0 (en
NO326939B1 (en
Inventor
Terrance P Snutch
Original Assignee
Neuromed Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuromed Tech Inc filed Critical Neuromed Tech Inc
Publication of NO20022948D0 publication Critical patent/NO20022948D0/en
Publication of NO20022948L publication Critical patent/NO20022948L/en
Publication of NO326939B1 publication Critical patent/NO326939B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20022948A 1999-12-20 2002-06-19 Calcium channel blocking compounds and pharmaceutical composition NO326939B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17276599P 1999-12-20 1999-12-20
US47692999A 1999-12-30 1999-12-30
PCT/CA2000/001558 WO2001046166A2 (en) 1999-12-20 2000-12-20 Partially saturated calcium channel blockers

Publications (3)

Publication Number Publication Date
NO20022948D0 NO20022948D0 (en) 2002-06-19
NO20022948L true NO20022948L (en) 2002-08-19
NO326939B1 NO326939B1 (en) 2009-03-16

Family

ID=26868438

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20022948A NO326939B1 (en) 1999-12-20 2002-06-19 Calcium channel blocking compounds and pharmaceutical composition

Country Status (7)

Country Link
EP (1) EP1242398A2 (en)
JP (1) JP2003518107A (en)
AU (1) AU784848B2 (en)
CA (1) CA2397681C (en)
MX (1) MXPA02006137A (en)
NO (1) NO326939B1 (en)
WO (1) WO2001046166A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2563304T3 (en) 2003-04-24 2016-03-14 Incyte Holdings Corporation Azaespiro alkane derivatives as metalloprotease inhibitors
ATE313532T1 (en) 2003-07-22 2006-01-15 Arena Pharm Inc DIARYL AND ARYLHETEROARYL UREA DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONINE RECEPTOR, SUITABLE FOR THE PROPHYLAXIS AND TREATMENT OF RELATED DISEASES
US7737163B2 (en) 2004-06-15 2010-06-15 Pfizer Inc. Benzimidazolone carboxylic acid derivatives
MXPA06014486A (en) 2004-06-15 2007-03-01 Pfizer Benzimidazolone carboxylic acid derivatives.
JP2008511552A (en) 2004-08-30 2008-04-17 ニューロメッド ファーマシューティカルズ リミテッド Urea derivatives as calcium channel blockers
US7511077B2 (en) 2005-02-09 2009-03-31 Neuromed Pharmaceuticals Ltd. Diamine calcium channel blockers
EP1856110B1 (en) 2005-02-22 2011-06-22 Pfizer Inc. Oxyindole derivatives as 5ht4 receptor agonists
WO2008031227A1 (en) * 2006-09-14 2008-03-20 Neuromed Pharmaceuticals Ltd. Diaryl piperidine compounds as calcium channel blockers
TWI415845B (en) 2006-10-03 2013-11-21 Arena Pharm Inc Pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
MY148880A (en) 2006-10-20 2013-06-14 Astrazeneca Ab N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression
WO2009023253A2 (en) 2007-08-15 2009-02-19 Arena Pharmaceuticals Inc. IMIDAZO[L,2-α]PYRIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
WO2010062321A1 (en) 2008-10-28 2010-06-03 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
HUE036506T2 (en) 2008-10-28 2018-07-30 Arena Pharm Inc Compositions comprising a 5-HT2A serotonin receptor modulator for the treatment of disorders associated with such receptor modulators
WO2011148888A1 (en) 2010-05-27 2011-12-01 あすか製薬株式会社 Heterocyclic ring compound and h1 receptor antagonist
EP3288527B1 (en) 2015-04-28 2020-02-19 Unilever PLC, a company registered in England and Wales under company no. 41424 of N-aralkylcarbonyldiamine compounds and personal care compositions comprising the same
EP3288926B1 (en) 2015-04-28 2021-01-20 Unilever PLC N-aralkylcarbonyl-piperazine and -homopiperazine compounds and personal care compositions comprising the same
CA2989343A1 (en) 2015-06-12 2016-12-15 Yandong Wen Diaryl and arylheteroaryl urea derivatives useful for the prophylaxis and treatment of rem sleep behavior disorder
JP2018520187A (en) 2015-07-15 2018-07-26 アクソヴァント サイエンシーズ ゲゼルシャフト ミット ベシュレンクテル ハフツングAxovant Sciences GmbH Diaryl and arylheteroaryl urea derivatives as modulators of 5-HT2A serotonin receptors useful for the prevention and treatment of hallucinations associated with neurodegenerative diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703071A (en) * 1990-08-29 1997-12-30 Pharmacia & Upjohn Company Tropolone derivatives and pharmaceutical composition thereof for preventing and treating ischemic diseases
DE4111861A1 (en) * 1991-04-11 1992-10-15 Schwabe Willmar Gmbh & Co BENZOPYRANONE, PROCESS FOR THEIR PREPARATION AND USE
US5292726A (en) * 1991-05-22 1994-03-08 Merck & Co., Inc. N,N-diacylpiperazines
BR9406080A (en) * 1993-12-08 1996-02-06 Alcon Lab Inc Compounds that have both potent anaonist antivity and antioxidant activity and their use as cytoprotective agents
KR20010013387A (en) * 1997-06-16 2001-02-26 디르크 반테 Use of draflazine-analogues for treating pain
US6251919B1 (en) * 1998-02-27 2001-06-26 Warner-Lambert Heterocyclic substituted aniline calcium channel blockers
US6011035A (en) * 1998-06-30 2000-01-04 Neuromed Technologies Inc. Calcium channel blockers

Also Published As

Publication number Publication date
WO2001046166A2 (en) 2001-06-28
CA2397681C (en) 2011-03-15
AU2495701A (en) 2001-07-03
NO20022948D0 (en) 2002-06-19
AU784848B2 (en) 2006-07-06
NO326939B1 (en) 2009-03-16
JP2003518107A (en) 2003-06-03
CA2397681A1 (en) 2001-06-28
EP1242398A2 (en) 2002-09-25
WO2001046166A3 (en) 2002-03-07
MXPA02006137A (en) 2002-12-05

Similar Documents

Publication Publication Date Title
NO20022948D0 (en) Partially saturated calcium channel blocking compounds
EP1296699A4 (en) THERAPEUTIC COMPOUNDS
NO20024042L (en) Aryl-fused azapolycyclic compounds
NO20026196L (en) Kinazolinditosylatsalt compounds
LTC1124961I2 (en) THROMBOPOETINE COMPOUNDS
ATE229954T1 (en) BETACARBOLINE COMPOUNDS
ID28266A (en) AMIDIN COMPOUNDS
DE69905038D1 (en) CYCLIC BOROPROLIN COMPOUNDS
EE200100502A (en) Compounds
NO20011745L (en) compounds
NO20015722D0 (en) Antibacterial compounds
ID27004A (en) CALSILITIC COMPOUNDS
ATE362919T1 (en) LACTAM COMPOUNDS
ATE405580T1 (en) ANTITHRBOTIC COMPOUNDS
ATE258921T1 (en) ARYL-ANNELLED AZAPOLYCYCLIC COMPOUNDS
NO20006662L (en) Fluorfenylresin compounds
NO20013769L (en) Calcilitic compounds
ATE372338T1 (en) DESHALOGEN COMPOUNDS
NO20020466L (en) Calcilitic compounds
NO20030303L (en) Calcilitic compounds
NO20031837D0 (en) Calcilitic compounds
NO20023508L (en) Calcilitic compounds
DK1175417T3 (en) Substituted benzolactam compounds
ATE235487T1 (en) S-OXYDE LIPIDE-LOWERING COMPOUNDS
DE50108778D1 (en) Dialkyne compounds

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees