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NO20020308L - Process for the preparation of epothilone B and its derivatives and intermediates for the process - Google Patents

Process for the preparation of epothilone B and its derivatives and intermediates for the process

Info

Publication number
NO20020308L
NO20020308L NO20020308A NO20020308A NO20020308L NO 20020308 L NO20020308 L NO 20020308L NO 20020308 A NO20020308 A NO 20020308A NO 20020308 A NO20020308 A NO 20020308A NO 20020308 L NO20020308 L NO 20020308L
Authority
NO
Norway
Prior art keywords
epothilone
intermediates
derivatives
preparation
Prior art date
Application number
NO20020308A
Other languages
Norwegian (no)
Other versions
NO20020308D0 (en
Inventor
Johann Mulzer
Harry Martin
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20020308D0 publication Critical patent/NO20020308D0/en
Publication of NO20020308L publication Critical patent/NO20020308L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • C07F7/1872Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20020308A 1999-07-22 2002-01-21 Process for the preparation of epothilone B and its derivatives and intermediates for the process NO20020308L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14500599P 1999-07-22 1999-07-22
PCT/US2000/020064 WO2001007439A2 (en) 1999-07-22 2000-07-24 Process for the production of epothiolone b and derivatives as well as intermediate products for this process

Publications (2)

Publication Number Publication Date
NO20020308D0 NO20020308D0 (en) 2002-01-21
NO20020308L true NO20020308L (en) 2002-03-21

Family

ID=22511165

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20020308A NO20020308L (en) 1999-07-22 2002-01-21 Process for the preparation of epothilone B and its derivatives and intermediates for the process

Country Status (5)

Country Link
EP (1) EP1226142A2 (en)
JP (1) JP2003505459A (en)
AU (1) AU6233600A (en)
NO (1) NO20020308L (en)
WO (1) WO2001007439A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204388B1 (en) 1996-12-03 2001-03-20 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
AU756699B2 (en) 1996-12-03 2003-01-23 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
DK1483251T3 (en) 2002-03-12 2010-04-12 Bristol Myers Squibb Co C3-cyano-epothilone derivatives
GB0221312D0 (en) * 2002-09-13 2002-10-23 Novartis Ag Organic compounds
DK2173756T3 (en) * 2007-07-04 2011-07-18 Sanofi Aventis Macrolactone derivatives
MX2012013100A (en) 2010-05-18 2013-01-22 Cerulean Pharma Inc Compositions and methods for treatment of autoimmune and other diseases.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1186606T4 (en) * 1995-11-17 2011-12-05 Biotechnolog Forschung Gmbh Epothilone derivatives, their preparation and use

Also Published As

Publication number Publication date
NO20020308D0 (en) 2002-01-21
EP1226142A2 (en) 2002-07-31
WO2001007439A2 (en) 2001-02-01
WO2001007439A3 (en) 2001-05-03
AU6233600A (en) 2001-02-13
JP2003505459A (en) 2003-02-12

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