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NO20013900L - Epotilonderivater, fremgangsmåter for fremstilling av disse og farmasöytisk anvendelse av dem - Google Patents

Epotilonderivater, fremgangsmåter for fremstilling av disse og farmasöytisk anvendelse av dem

Info

Publication number
NO20013900L
NO20013900L NO20013900A NO20013900A NO20013900L NO 20013900 L NO20013900 L NO 20013900L NO 20013900 A NO20013900 A NO 20013900A NO 20013900 A NO20013900 A NO 20013900A NO 20013900 L NO20013900 L NO 20013900L
Authority
NO
Norway
Prior art keywords
processes
preparation
pharmaceutical use
epothilone derivatives
epothilone
Prior art date
Application number
NO20013900A
Other languages
English (en)
Other versions
NO20013900D0 (no
Inventor
Ulrich Klar
Werner Skuballa
Bernd Buchmann
Wolfgang Schwede
Michael Schirner
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1999107480 external-priority patent/DE19907480A1/de
Priority claimed from DE19954229A external-priority patent/DE19954229A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20013900D0 publication Critical patent/NO20013900D0/no
Publication of NO20013900L publication Critical patent/NO20013900L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20013900A 1999-02-11 2001-08-10 Epotilonderivater, fremgangsmåter for fremstilling av disse og farmasöytisk anvendelse av dem NO20013900L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1999107480 DE19907480A1 (de) 1999-02-11 1999-02-11 Epothilon-Derivate, Verfahren zu deren Herstellung und ihre pharmazeutische Verwendung
DE19954229A DE19954229A1 (de) 1999-11-04 1999-11-04 Epothilon-Derivate, Verfahren zu deren Herstellung und ihre pharmazeutische Verwendung
PCT/EP2000/001104 WO2000047584A2 (de) 1999-02-11 2000-02-11 Epothilon-derivate, verfahren zu deren herstellung und ihre pharmazeutische verwendung

Publications (2)

Publication Number Publication Date
NO20013900D0 NO20013900D0 (no) 2001-08-10
NO20013900L true NO20013900L (no) 2001-10-11

Family

ID=26051977

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013900A NO20013900L (no) 1999-02-11 2001-08-10 Epotilonderivater, fremgangsmåter for fremstilling av disse og farmasöytisk anvendelse av dem

Country Status (21)

Country Link
US (2) US7001916B1 (no)
EP (1) EP1161430A2 (no)
JP (1) JP2002536450A (no)
KR (1) KR20010094763A (no)
CN (1) CN1340053A (no)
AU (1) AU4101800A (no)
BG (1) BG105803A (no)
BR (1) BR0008206A (no)
CA (1) CA2360952A1 (no)
CZ (1) CZ20012886A3 (no)
EA (1) EA200100833A1 (no)
EE (1) EE200100422A (no)
HK (1) HK1044946A1 (no)
HU (1) HUP0105330A2 (no)
IL (1) IL144370A0 (no)
MX (1) MXPA01008148A (no)
NO (1) NO20013900L (no)
PL (1) PL350190A1 (no)
SK (1) SK11452001A3 (no)
WO (1) WO2000047584A2 (no)
YU (1) YU57601A (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU756699B2 (en) 1996-12-03 2003-01-23 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US6204388B1 (en) 1996-12-03 2001-03-20 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
US6660758B1 (en) * 1996-12-13 2003-12-09 The Scripps Research Institute Epothilone analogs
AU772750C (en) * 1999-04-30 2005-02-24 Schering Aktiengesellschaft 6-alkenyl-, 6-alkinyl- and 6-epoxy-epothilone derivatives, process for their production, and their use in pharmaceutical preparations
ATE434438T1 (de) * 2001-02-27 2009-07-15 Novartis Pharma Gmbh Kombination enthaltend einen inhibitor der signaltransduktion und ein epothilonderivat
WO2003018002A2 (en) 2001-08-23 2003-03-06 Novartis Ag Cyclopropyl and cyclobutyl epothilone analogs
DK1483251T3 (da) 2002-03-12 2010-04-12 Bristol Myers Squibb Co C3-cyano-epothilon-derivater
ATE476995T1 (de) * 2002-06-10 2010-08-15 Novartis Pharma Gmbh Epothilone enthaltende kombinationen und deren pharmazeutische verwendungen
MXPA05001104A (es) * 2002-07-31 2005-09-08 Eisai Co Ltd Nuevas sustancias fisiologicamente activas.
US20050215604A1 (en) * 2004-03-26 2005-09-29 Kosan Biosciences, Inc. Combination therapies with epothilones and carboplatin
EP1589011A1 (en) * 2004-04-22 2005-10-26 Schering Aktiengesellschaft Novel chiral heptyne derivates for the preparation of epothilones and processes for their preparation
WO2007086879A2 (en) 2005-02-11 2007-08-02 University Of Southern California Method of expressing proteins with disulfide bridges
EP2029156A4 (en) * 2006-05-01 2010-07-21 Univ Southern California COMBINATION THERAPY FOR CANCER TREATMENT
US20100113128A1 (en) * 2008-11-05 2010-05-06 Snow Richard N Methods and apparatus for determining a reel strip position
WO2010056901A2 (en) 2008-11-13 2010-05-20 University Of Southern California Method of expressing proteins with disulfide bridges with enhanced yields and activity
US20100125146A1 (en) * 2008-11-19 2010-05-20 Johnson Matthey Public Limited Company Method for making pharmaceutical compounds
MX2012013100A (es) 2010-05-18 2013-01-22 Cerulean Pharma Inc Composiciones y metodos para el tratamiento de enfermedades autoinmunes y otras enfermedades.
MA43178A (fr) 2015-10-16 2018-09-12 Univ Rice William M Analogues d'épothilone, procédés de synthèse, procédés de traitement, et conjugués médicamenteux de ceux-ci
WO2017096559A1 (en) 2015-12-09 2017-06-15 Rhodia Operations Production of xylene derivatives

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4138042C2 (de) 1991-11-19 1993-10-14 Biotechnolog Forschung Gmbh Epothilone, deren Herstellungsverfahren sowie diese Verbindungen enthaltende Mittel
US5469145A (en) 1992-05-29 1995-11-21 Johnson; Lonnie Wet diaper detector
DK1186606T4 (da) 1995-11-17 2011-12-05 Biotechnolog Forschung Gmbh Epothilonderivater, deres fremstilling og anvendelse
US6441025B2 (en) 1996-03-12 2002-08-27 Pg-Txl Company, L.P. Water soluble paclitaxel derivatives
DE19636343C1 (de) 1996-08-30 1997-10-23 Schering Ag Zwischenprodukte innerhalb der Totalsynthese von Epothilon A und B
US5969145A (en) 1996-08-30 1999-10-19 Novartis Ag Process for the production of epothilones and intermediate products within the process
NZ334821A (en) 1996-08-30 2000-12-22 Novartis Ag Method for producing epothilones
US6867305B2 (en) * 1996-12-03 2005-03-15 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
AU756699B2 (en) * 1996-12-03 2003-01-23 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US6441186B1 (en) * 1996-12-13 2002-08-27 The Scripps Research Institute Epothilone analogs
DE19701758A1 (de) 1997-01-20 1998-07-23 Wessjohann Ludgar A Dr Epothilone-Synthesebausteine
US6605599B1 (en) * 1997-07-08 2003-08-12 Bristol-Myers Squibb Company Epothilone derivatives
PT1005465E (pt) 1997-08-09 2007-10-18 Bayer Schering Pharma Ag Novos derivados da epotilona, processo para a sua preparação e sua utilização farmacêutica
AU4775299A (en) 1998-06-22 2000-01-10 Nicolaou, Kyriacos Costa Desmethyl epothilones
AU6208701A (en) 2000-03-09 2001-09-17 Schering Aktiengesellschaft Radioactively labeled epothilone derivatives, method for the production thereof, and their biochemical and pharmaceutical use
CA2359267A1 (en) 2000-10-19 2002-04-19 Manabu Takami Wavelength selecting module and wavelength selecting apparatus
EP1340498A1 (en) * 2002-03-01 2003-09-03 Schering Aktiengesellschaft Use of epothilones in the treatment of brain diseases associated with proliferative processes
EP1524979A2 (en) * 2002-07-31 2005-04-27 Schering AG New effector conjugates, process for their production and their pharmaceutical use
WO2004015088A2 (en) 2002-08-13 2004-02-19 Kosan Biosciences, Inc. Transposon-based transformation system

Also Published As

Publication number Publication date
HUP0105330A2 (hu) 2002-05-29
YU57601A (sh) 2005-06-10
KR20010094763A (ko) 2001-11-01
CA2360952A1 (en) 2000-08-17
WO2000047584A3 (de) 2000-12-28
CZ20012886A3 (cs) 2001-11-14
EE200100422A (et) 2002-12-16
SK11452001A3 (sk) 2002-04-04
US20060040990A1 (en) 2006-02-23
WO2000047584A2 (de) 2000-08-17
BG105803A (en) 2002-03-29
EA200100833A1 (ru) 2002-02-28
JP2002536450A (ja) 2002-10-29
NO20013900D0 (no) 2001-08-10
BR0008206A (pt) 2002-02-19
IL144370A0 (en) 2002-05-23
PL350190A1 (en) 2002-11-18
HK1044946A1 (zh) 2002-11-08
EP1161430A2 (de) 2001-12-12
CN1340053A (zh) 2002-03-13
MXPA01008148A (es) 2003-07-21
US7001916B1 (en) 2006-02-21
AU4101800A (en) 2000-08-29

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application