NO20004545L - FremgangsmÕte for fremstilling av (R)-<alfa>-(2,3- dimetoksyfenyl)-1-[2-(4-fluorofenyl)etyl]-4-piperidinmetanol - Google Patents

FremgangsmÕte for fremstilling av (R)-<alfa>-(2,3- dimetoksyfenyl)-1-[2-(4-fluorofenyl)etyl]-4-piperidinmetanol

Info

Publication number: NO20004545L
Authority: NO; Norway
Prior art keywords: piperidinemethanol; dimethoxyphenyl; fluorophenyl; alpha; ethyl
Prior art date: 1998-03-13

Application number

NO20004545A

Other languages

English (en)

Other versions

NO317981B1 (no

NO20004545D0 (no

Inventor

Alan G Bina

Edward D Daugs

Jonathan Charles Evans

Hans-Wolfram Flemming

Gerard Guillamot

Robert A Hawthorne

Thomas H E Hilpert

James E Hitt

Chi-Hsin R King

Johannes N Koek

Frederick M Laskovics

John Robert Lefler

Alexey Leonid Margolin

Sharon Kay Minish

Thomas T Ortyl

Lian G Rajewski

Marvin J Sack

Paul F Skultety

Sandra Kaye Stolz-Dunn

Alonzo L Tigner

Ian A Tomlinson

Original Assignee

Aventis Pharma Inc

Hoechst Marion Roussel De Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-13

Filing date

2000-09-12

Publication date

2000-11-13

2000-09-12 Application filed by Aventis Pharma Inc, Hoechst Marion Roussel De Gmbh filed Critical Aventis Pharma Inc

2000-09-12 Publication of NO20004545D0 publication Critical patent/NO20004545D0/no

2000-11-13 Publication of NO20004545L publication Critical patent/NO20004545L/no

2005-01-17 Publication of NO317981B1 publication Critical patent/NO317981B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pulmonology (AREA)
Psychiatry (AREA)
Hematology (AREA)
Nutrition Science (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Otolaryngology (AREA)
Diabetes (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Medicinal Preparation (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

NO20004545A 1998-03-13 2000-09-12 Fremgangsmate for fremstilling av (R)-<alfa>-(2,3-dimetoksyfenyl)-1-[2-(4-fluorofenyl)etyl]-4-piperidinmetanol, mellomprodukter for bruk ved fremstilling av denne forbindelse og fremgangsmpter for fremstilling av noen av disse mellomprodukter NO317981B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US4225198A	1998-03-13	1998-03-13
US25071899A	1999-02-16	1999-02-16
PCT/US1999/005332 WO1999046245A2 (en)	1998-03-13	1999-03-11	PROCESSES FOR THE PREPARATION OF (R)-α- (2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINEMETHANOL

Publications (3)

Publication Number	Publication Date
NO20004545D0 NO20004545D0 (no)	2000-09-12
NO20004545L true NO20004545L (no)	2000-11-13
NO317981B1 NO317981B1 (no)	2005-01-17

Family

ID=26719032

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20004545A NO317981B1 (no)	1998-03-13	2000-09-12	Fremgangsmate for fremstilling av (R)-<alfa>-(2,3-dimetoksyfenyl)-1-[2-(4-fluorofenyl)etyl]-4-piperidinmetanol, mellomprodukter for bruk ved fremstilling av denne forbindelse og fremgangsmpter for fremstilling av noen av disse mellomprodukter

Country Status (25)

Country	Link
EP (3)	EP1734037A3 (no)
JP (2)	JP4511723B2 (no)
KR (7)	KR100591640B1 (no)
CN (1)	CN100436415C (no)
AR (1)	AR015540A1 (no)
AT (1)	ATE373639T1 (no)
AU (1)	AU755436B2 (no)
BR (1)	BR9909260A (no)
CA (1)	CA2322501C (no)
CY (1)	CY1107104T1 (no)
DE (1)	DE69937162T2 (no)
DK (1)	DK1192134T3 (no)
DZ (1)	DZ2742A1 (no)
EG (1)	EG24052A (no)
ES (1)	ES2294838T3 (no)
HK (1)	HK1042484B (no)
HU (1)	HUP0400889A3 (no)
IL (3)	IL138307A0 (no)
MA (1)	MA25515A1 (no)
NO (1)	NO317981B1 (no)
NZ (1)	NZ506807A (no)
PT (1)	PT1192134E (no)
TN (1)	TNSN99035A1 (no)
TW (1)	TWI249526B (no)
WO (1)	WO1999046245A2 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6713627B2 (en) *	1998-03-13	2004-03-30	Aventis Pharmaceuticals Inc.	Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
DE19934432A1 (de)	1999-07-22	2001-02-01	Merck Patent Gmbh	Indolderivate
WO2002072069A1 (en) *	2001-03-12	2002-09-19	Novo Nordisk A/S	Novel tablets and capsules and a process for its preparation
DE102004010132A1 (de)	2004-02-27	2005-09-15	Merck Patent Gmbh	Piperidinderivate
TWI428151B (zh) *	2006-12-07	2014-03-01	Daiichi Sankyo Co Ltd	含有甘露醇或乳糖之固形製劑
US8964338B2 (en)	2012-01-11	2015-02-24	Emerson Climate Technologies, Inc.	System and method for compressor motor protection
WO2014144446A1 (en)	2013-03-15	2014-09-18	Emerson Electric Co.	Hvac system remote monitoring and diagnosis
CN112358398A (zh) *	2020-11-19	2021-02-12	山东新华制药股份有限公司	D-(+)-二对甲苯甲酰酒石酸的回收制备方法
CN116082705B (zh) *	2022-12-05	2023-09-12	苏州易昇光学材料股份有限公司	一种抗黄变自修复凝胶

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4260623A (en) *	1979-11-26	1981-04-07	Warner-Lambert Company	Hexahydro-1-arylspiro(3H-oxazolo(3,4-A)pyridine-3,4'-piperidene) antidepressants, pharmaceutical compositions thereof and method of use thereof
US5169096A (en) *	1985-07-02	1992-12-08	Merrell Dow Pharmaceuticals Inc.	N-aralkyl-piperidine-methanol derivatives
CA1280421C (en) *	1985-07-02	1991-02-19	Albert A. Carr	1,4-disubstituted piperidinyl derivatives
HU213271B (en) *	1990-06-01	1997-04-28	Merrell Dow Pharma	Process for producing (+)-alpha-(2,3-dimethoxi-phenyl)-1-[2-(4-fluoric-phenyl)-ethyl]-4-piperidine-methanole and pharmaceutical compositions containing the same
ATE144899T1 (de) *	1990-06-07	1996-11-15	Merrell Pharma Inc	Derivate des 1-piperidinyl- alkanoylarylsulfonamids
US5477029A (en) *	1994-01-28	1995-12-19	Skutt Ceramic Products, Inc.	Kiln with hinged control panel
US5618824A (en) *	1994-03-09	1997-04-08	Merrell Pharmaceuticals Inc.	Treatment of obsessive-compulsive disorders with 5-HT2 antagonists
EP0796619A1 (en) *	1996-03-21	1997-09-24	Merrell Pharmaceuticals Inc.	Use of (+)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4-piperidinemethanol in treating depressive disorders and bipolar disorders

1999
- 1999-03-09 TW TW088103619A patent/TWI249526B/zh not_active IP Right Cessation
- 1999-03-10 EG EG23399A patent/EG24052A/xx active
- 1999-03-10 MA MA25491A patent/MA25515A1/fr unknown
- 1999-03-10 DZ DZ990043A patent/DZ2742A1/xx active
- 1999-03-11 KR KR1020057024568A patent/KR100591640B1/ko not_active IP Right Cessation
- 1999-03-11 WO PCT/US1999/005332 patent/WO1999046245A2/en active IP Right Grant
- 1999-03-11 BR BR9909260-3A patent/BR9909260A/pt not_active Application Discontinuation
- 1999-03-11 HU HU0400889A patent/HUP0400889A3/hu unknown
- 1999-03-11 IL IL13830799A patent/IL138307A0/xx active IP Right Grant
- 1999-03-11 AU AU29988/99A patent/AU755436B2/en not_active Ceased
- 1999-03-11 AR ARP990101039A patent/AR015540A1/es unknown
- 1999-03-11 KR KR1020057024570A patent/KR100586328B1/ko not_active IP Right Cessation
- 1999-03-11 DE DE69937162T patent/DE69937162T2/de not_active Expired - Lifetime
- 1999-03-11 KR KR1020057024569A patent/KR100586327B1/ko not_active IP Right Cessation
- 1999-03-11 EP EP06016486A patent/EP1734037A3/en not_active Ceased
- 1999-03-11 EP EP06016487A patent/EP1736469A3/en not_active Withdrawn
- 1999-03-11 KR KR1020057024567A patent/KR100591643B1/ko not_active IP Right Cessation
- 1999-03-11 KR KR1020057024572A patent/KR100591997B1/ko not_active IP Right Cessation
- 1999-03-11 JP JP2000535626A patent/JP4511723B2/ja not_active Expired - Fee Related
- 1999-03-11 AT AT99911318T patent/ATE373639T1/de not_active IP Right Cessation
- 1999-03-11 TN TNTNSN99035A patent/TNSN99035A1/fr unknown
- 1999-03-11 PT PT99911318T patent/PT1192134E/pt unknown
- 1999-03-11 CA CA002322501A patent/CA2322501C/en not_active Expired - Fee Related
- 1999-03-11 DK DK99911318T patent/DK1192134T3/da active
- 1999-03-11 EP EP99911318A patent/EP1192134B1/en not_active Expired - Lifetime
- 1999-03-11 KR KR1020057024573A patent/KR100591641B1/ko not_active IP Right Cessation
- 1999-03-11 KR KR1020007010103A patent/KR100591642B1/ko not_active IP Right Cessation
- 1999-03-11 NZ NZ506807A patent/NZ506807A/xx unknown
- 1999-03-11 CN CNB998060224A patent/CN100436415C/zh not_active Expired - Fee Related
- 1999-03-11 ES ES99911318T patent/ES2294838T3/es not_active Expired - Lifetime
2000
- 2000-09-06 IL IL138307A patent/IL138307A/en not_active IP Right Cessation
- 2000-09-12 NO NO20004545A patent/NO317981B1/no not_active IP Right Cessation
2002
- 2002-05-08 HK HK02103493.4A patent/HK1042484B/zh not_active IP Right Cessation
2006
- 2006-05-29 IL IL175983A patent/IL175983A0/en unknown
2007
- 2007-12-19 CY CY20071101617T patent/CY1107104T1/el unknown
2009
- 2009-12-28 JP JP2009296809A patent/JP2010143925A/ja not_active Abandoned

Also Published As

Publication number	Publication date
KR20060002034A (ko)	2006-01-06
KR100591640B1 (ko)	2006-06-20
IL175983A0 (en)	2006-10-05
DZ2742A1 (fr)	2003-09-08
CN100436415C (zh)	2008-11-26
KR100591642B1 (ko)	2006-06-20
KR100591641B1 (ko)	2006-06-20
CA2322501A1 (en)	1999-09-16
EP1734037A3 (en)	2010-06-16
NO317981B1 (no)	2005-01-17
KR20060002038A (ko)	2006-01-06
CN1300280A (zh)	2001-06-20
HUP0400889A2 (hu)	2004-08-30
DE69937162T2 (de)	2008-06-12
NO20004545D0 (no)	2000-09-12
EP1192134A2 (en)	2002-04-03
KR100586327B1 (ko)	2006-06-08
KR20060002039A (ko)	2006-01-06
KR100591643B1 (ko)	2006-06-20
EP1736469A2 (en)	2006-12-27
JP2010143925A (ja)	2010-07-01
WO1999046245A3 (en)	1999-10-21
PT1192134E (pt)	2007-11-13
HK1042484A1 (en)	2002-08-16
TNSN99035A1 (fr)	2005-11-10
EP1192134B1 (en)	2007-09-19
JP2002506059A (ja)	2002-02-26
KR20010041819A (ko)	2001-05-25
MA25515A1 (fr)	2002-10-01
AR015540A1 (es)	2001-05-02
AU755436B2 (en)	2002-12-12
IL138307A0 (en)	2001-10-31
EP1736469A3 (en)	2010-06-09
HK1042484B (zh)	2008-05-02
DK1192134T3 (da)	2007-11-26
CY1107104T1 (el)	2012-01-25
HUP0400889A3 (en)	2010-08-30
ES2294838T3 (es)	2008-04-01
BR9909260A (pt)	2000-11-21
ATE373639T1 (de)	2007-10-15
WO1999046245A2 (en)	1999-09-16
CA2322501C (en)	2006-05-09
KR100586328B1 (ko)	2006-06-08
NZ506807A (en)	2003-03-28
DE69937162D1 (de)	2007-10-31
EP1734037A2 (en)	2006-12-20
TWI249526B (en)	2006-02-21
KR20060002037A (ko)	2006-01-06
KR100591997B1 (ko)	2006-06-26
AU2998899A (en)	1999-09-27
KR20060002035A (ko)	2006-01-06
EG24052A (en)	2008-04-13
KR20060002036A (ko)	2006-01-06
JP4511723B2 (ja)	2010-07-28
IL138307A (en)	2006-09-05

Publication	Publication Date	Title
EE9900441A (et)	2000-04-17	Farmatseutiline kompositsioon N-piperidino-3-pürasoolkarboksamiidi derivaadi, tema soolade ja nende solvaatide suu kaudu manustamiseks
IL175983A0 (en)	2006-10-05	Processes and intermediates for the preparation of (r) -??-(2,3 - dimethoxyphenyl) - 1 - [2 - (4-fluorophenyl) ethyl] - 4 - piperidine methanol
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