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NO20003694D0 - VLA-4 antagonists - Google Patents

VLA-4 antagonists

Info

Publication number
NO20003694D0
NO20003694D0 NO20003694A NO20003694A NO20003694D0 NO 20003694 D0 NO20003694 D0 NO 20003694D0 NO 20003694 A NO20003694 A NO 20003694A NO 20003694 A NO20003694 A NO 20003694A NO 20003694 D0 NO20003694 D0 NO 20003694D0
Authority
NO
Norway
Prior art keywords
vla
antagonists
Prior art date
Application number
NO20003694A
Other languages
Norwegian (no)
Other versions
NO20003694L (en
Inventor
Sompong Wattanasin
Peter Josef Von Matt
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20003694D0 publication Critical patent/NO20003694D0/en
Publication of NO20003694L publication Critical patent/NO20003694L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20003694A 1998-01-23 2000-07-19 VLA-4 antagonists NO20003694L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1233698A 1998-01-23 1998-01-23
US11072398P 1998-12-03 1998-12-03
PCT/EP1999/000384 WO1999037605A1 (en) 1998-01-23 1999-01-21 Vla-4 antagonists

Publications (2)

Publication Number Publication Date
NO20003694D0 true NO20003694D0 (en) 2000-07-19
NO20003694L NO20003694L (en) 2000-09-20

Family

ID=26683440

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003694A NO20003694L (en) 1998-01-23 2000-07-19 VLA-4 antagonists

Country Status (13)

Country Link
EP (1) EP1049665A1 (en)
JP (1) JP4564654B2 (en)
KR (1) KR20010034317A (en)
CN (1) CN1294576A (en)
AU (1) AU746174B2 (en)
BR (1) BR9907733A (en)
CA (1) CA2318639A1 (en)
EE (1) EE200000428A (en)
HU (1) HUP0100336A3 (en)
ID (1) ID26665A (en)
IL (1) IL137329A0 (en)
NO (1) NO20003694L (en)
WO (1) WO1999037605A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000043372A1 (en) * 1999-01-22 2000-07-27 Elan Pharmaceuticals, Inc. Acyl derivatives which treat vla-4 related disorders
ATE455106T1 (en) 1999-01-22 2010-01-15 Elan Pharm Inc ACYL DERIVATIVES FOR THE TREATMENT OF VLA-4 RELATED DISEASES
US6436904B1 (en) 1999-01-25 2002-08-20 Elan Pharmaceuticals, Inc. Compounds which inhibit leukocyte adhesion mediated by VLA-4
JP2002538135A (en) 1999-03-01 2002-11-12 エラン ファーマシューティカルズ,インコーポレイテッド α-aminoacetic acid derivatives useful as α4β7 receptor antagonists
WO2001042192A2 (en) * 1999-12-07 2001-06-14 Novartis Ag Vla-4 integrin antagonists
HUP0203897A3 (en) 1999-12-28 2005-06-28 Pfizer Prod Inc Non-peptidyl inhibitors of vla-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases
DE10019755A1 (en) * 2000-04-20 2001-11-08 Bayer Ag New cyclic carboxylic acids are integrin antagonists, useful for treating inflammatory diseases, autoimmune and immune disorders, e.g. atherosclerosis, asthma and diabetes
GB2367816A (en) 2000-10-09 2002-04-17 Bayer Ag Urea- and thiourea-containing derivatives of beta-amino acids
GB2369357A (en) * 2000-10-09 2002-05-29 Bayer Ag Aliphatic, cyclic amino carboxylic acids as integrin antagonists
GB2377933A (en) 2001-07-06 2003-01-29 Bayer Ag Succinic acid derivatives useful as integrin antagonists
TW200307671A (en) 2002-05-24 2003-12-16 Elan Pharm Inc Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
TWI281470B (en) 2002-05-24 2007-05-21 Elan Pharm Inc Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins
TW200610754A (en) * 2004-06-14 2006-04-01 Daiichi Seiyaku Co Vla-4 inhibitor
GB0523576D0 (en) * 2005-11-18 2005-12-28 Theradeas Ltd Drug composition and its use in therapy
NZ570679A (en) 2006-02-27 2011-01-28 Elan Pharm Inc Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated By VLA-4
CA2714335A1 (en) 2007-02-20 2008-08-28 Merrimack Pharmaceuticals, Inc. Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist
AU2009234253C1 (en) 2008-04-11 2015-05-07 Merrimack Pharmaceuticals, Inc. Human serum albumin linkers and conjugates thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306840B1 (en) * 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
ATE289991T1 (en) * 1997-12-23 2005-03-15 Aventis Pharma Ltd SUBSTITUTED BETA-ALANINES

Also Published As

Publication number Publication date
HUP0100336A2 (en) 2001-07-30
IL137329A0 (en) 2001-07-24
ID26665A (en) 2001-01-25
CA2318639A1 (en) 1999-07-29
EP1049665A1 (en) 2000-11-08
HUP0100336A3 (en) 2002-11-28
NO20003694L (en) 2000-09-20
WO1999037605A1 (en) 1999-07-29
KR20010034317A (en) 2001-04-25
JP4564654B2 (en) 2010-10-20
EE200000428A (en) 2001-12-17
CN1294576A (en) 2001-05-09
AU746174B2 (en) 2002-04-18
JP2002501039A (en) 2002-01-15
AU2829299A (en) 1999-08-09
BR9907733A (en) 2000-10-17

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application