NO178399C - Analogifremgangsmåte for fremstilling av terapeutisk aktive 3-piperidino-4-hydroksykromanderivater og analoger derav - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive 3-piperidino-4-hydroksykromanderivater og analoger derav

Info

Publication number: NO178399C
Authority: NO; Norway
Prior art keywords: piperidino; analogs; preparation; therapeutically active; analogous process
Prior art date: 1990-02-06

Application number

NO923081A

Other languages

English (en)

Other versions

NO923081L (no

NO923081D0 (no

NO178399B (no

Inventor

Todd W Butler

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-06

Filing date

1992-08-05

Publication date

1996-03-20

1992-08-05 Application filed by Pfizer filed Critical Pfizer

1992-08-05 Publication of NO923081L publication Critical patent/NO923081L/no

1992-08-05 Publication of NO923081D0 publication Critical patent/NO923081D0/no

1995-12-11 Publication of NO178399B publication Critical patent/NO178399B/no

1996-03-20 Publication of NO178399C publication Critical patent/NO178399C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO923081A 1990-02-06 1992-08-05 Analogifremgangsmåte for fremstilling av terapeutisk aktive 3-piperidino-4-hydroksykromanderivater og analoger derav NO178399C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US1990/000674 WO1991012005A1 (en)	1990-02-06	1990-02-06	Neuroprotective 3-piperidino-4-hydroxychroman derivatives and analogs

Publications (4)

Publication Number	Publication Date
NO923081L NO923081L (no)	1992-08-05
NO923081D0 NO923081D0 (no)	1992-08-05
NO178399B NO178399B (no)	1995-12-11
NO178399C true NO178399C (no)	1996-03-20

Family

ID=22220666

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO923081A NO178399C (no)	1990-02-06	1992-08-05	Analogifremgangsmåte for fremstilling av terapeutisk aktive 3-piperidino-4-hydroksykromanderivater og analoger derav

Country Status (29)

Country	Link
US (1)	US5356905A (no)
EP (1)	EP0441506B1 (no)
JP (1)	JPH0768214B2 (no)
KR (1)	KR930011041B1 (no)
CN (1)	CN1029960C (no)
AT (1)	ATE108787T1 (no)
AU (1)	AU626490B2 (no)
BR (1)	BR9100490A (no)
CA (1)	CA2035653C (no)
CZ (1)	CZ286218B6 (no)
DE (2)	DE69102893T4 (no)
DK (1)	DK0441506T3 (no)
EG (1)	EG19643A (no)
ES (1)	ES2056571T3 (no)
FI (1)	FI94957C (no)
HU (1)	HU222726B1 (no)
IE (1)	IE63836B1 (no)
IL (1)	IL97100A (no)
MX (1)	MX24433A (no)
MY (1)	MY105293A (no)
NO (1)	NO178399C (no)
NZ (1)	NZ237025A (no)
PH (1)	PH31061A (no)
PL (1)	PL164866B1 (no)
PT (1)	PT96664B (no)
RU (1)	RU2099339C1 (no)
SK (1)	SK281729B6 (no)
WO (1)	WO1991012005A1 (no)
ZA (1)	ZA91830B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5594007A (en) *	1991-04-18	1997-01-14	Pfizer Inc.	Method for treating spinal cord trauma with phenolic 2-piperidino-1-alkanols
CA2108557A1 (en) *	1991-04-18	1992-10-19	Bertrand L. Chenard	Prodrug esters of phenolic 2-piperidino-1-alkanols
US5436255A (en) *	1992-07-23	1995-07-25	Pfizer Inc.	Method of treating diseases susceptable to treatment by blocking NMDA-receptors
US5498610A (en) *	1992-11-06	1996-03-12	Pfizer Inc.	Neuroprotective indolone and related derivatives
ATE183184T1 (de) *	1994-01-31	1999-08-15	Pfizer	Neuroprotektive chroman verbindungen
NZ284852A (en) *	1994-08-18	1998-06-26	Pfizer	3-(piperidin-1-yl)-chroman-4,7-diol and 1-(4-hydrophenyl)-2-(piperidin-1-yl) alkanol derivatives; medicaments; used as a neuroprotective agent
ATE258067T1 (de)	1995-05-26	2004-02-15	Pfizer	Kombinationspräparat zur behandlung der parkinsonschen krankheit, das selektive nmda- antagonisten enthält
TW498067B (en) *	1996-07-19	2002-08-11	Hoffmann La Roche	4-hydroxy-piperidine derivatives
US6489477B1 (en)	1999-10-29	2002-12-03	Merck & Co., Inc.	2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
US6291499B1 (en)	1999-10-29	2001-09-18	Merck & Co., Inc.	2-cyclohexyl benzimidazole NMDA/NR2B antagonists
US6316474B1 (en)	1999-10-29	2001-11-13	Merck & Co., Inc.	2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
US6432976B1 (en)	1999-10-29	2002-08-13	Merck & Co., Inc.	8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6380205B1 (en)	1999-10-29	2002-04-30	Merck & Co., Inc.	2-cyclohexyl quinazoline NMDA/NR2B antagonists
CA2386441A1 (en)	1999-10-29	2001-05-03	Merck Sharp & Dohme Limited	Method to treat pain utilizing benzimidazole nmda/nr2b antagonists
US6369076B1 (en)	1999-10-29	2002-04-09	Merck & Co. Inc.	5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6495561B2 (en)	1999-10-29	2002-12-17	Merck & Co., Inc.	2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
US6476041B1 (en)	1999-10-29	2002-11-05	Merck & Co., Inc.	1,4 substituted piperidinyl NMDA/NR2B antagonists
IL145209A0 (en)	2000-09-06	2002-06-30	Pfizer Prod Inc	Pharmaceutical combinations for the treatment of stroke and traumatic brain injury
EP1674087A1 (en)	2000-10-02	2006-06-28	Pfizer Products Inc.	Prophylactic use of n-methyl-d-aspartate (NMDA) antagonists
US7217716B2 (en)	2001-02-23	2007-05-15	Merck & Co., Inc.	N-substituted nonaryl-heterocyclic NMDA/NR2B antagonists
US7259157B2 (en)	2001-04-03	2007-08-21	Merck & Co., Inc.	N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists
CA2542077A1 (en) *	2003-10-08	2005-04-21	President And Fellows Of Harvard College	Pyrovalerone analogs and therapeutic uses thereof
JP4864719B2 (ja) *	2003-11-26	2012-02-01	ファイザー・プロダクツ・インク	Ｇｓｋ−３インヒビターとしてのアミノピラゾール誘導体

Family Cites Families (8)

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Publication number	Priority date	Publication date	Assignee	Title
US3294804A (en) *	1961-01-27	1966-12-27	Sterling Drug Inc	1-(3-hydroxy-3-phenylpropyl)-4-phenyl-4-propionoxy-piperidine
FR5733M (no) *	1966-09-27	1968-01-22
GB1495526A (en) *	1974-05-31	1977-12-21	Beecham Group Ltd	Chroman derivatives
DE2507782A1 (de) *	1975-02-22	1976-09-02	Merck Patent Gmbh	Tetralon- und indanon-derivate sowie verfahren zu ihrer herstellung
US4016281A (en) *	1975-02-22	1977-04-05	Merck Patent Gesellschaft Mit Beschrankter Haftung	Tetralone and indanone compounds
ATE23718T1 (de) *	1981-09-25	1986-12-15	Beecham Group Plc	Benzopyran-verbindungen mit pharmazeutischer wirkung.
EP0093534A1 (en) *	1982-04-28	1983-11-09	Beecham Group Plc	Novel chromanols
GB8308064D0 (en) *	1983-03-24	1983-05-05	Beecham Group Plc	Active compounds

1990
- 1990-02-06 HU HU9202568A patent/HU222726B1/hu active IP Right Grant
- 1990-02-06 US US07/916,130 patent/US5356905A/en not_active Expired - Lifetime
- 1990-02-06 MX MX2443391A patent/MX24433A/es unknown
- 1990-02-06 RU SU5053040/04A patent/RU2099339C1/ru not_active IP Right Cessation
- 1990-02-06 WO PCT/US1990/000674 patent/WO1991012005A1/en active IP Right Grant
1991
- 1991-01-21 PH PH41875A patent/PH31061A/en unknown
- 1991-01-24 EP EP91300549A patent/EP0441506B1/en not_active Expired - Lifetime
- 1991-01-24 DK DK91300549.2T patent/DK0441506T3/da active
- 1991-01-24 ES ES91300549T patent/ES2056571T3/es not_active Expired - Lifetime
- 1991-01-24 AT AT91300549T patent/ATE108787T1/de not_active IP Right Cessation
- 1991-01-24 DE DE69102893A patent/DE69102893T4/de not_active Expired - Fee Related
- 1991-01-30 IL IL9710091A patent/IL97100A/en not_active IP Right Cessation
- 1991-02-01 SK SK250-91A patent/SK281729B6/sk unknown
- 1991-02-01 CZ CS1991250A patent/CZ286218B6/cs not_active IP Right Cessation
- 1991-02-04 CA CA002035653A patent/CA2035653C/en not_active Expired - Fee Related
- 1991-02-04 PT PT96664A patent/PT96664B/pt not_active IP Right Cessation
- 1991-02-04 PL PL91288949A patent/PL164866B1/pl not_active IP Right Cessation
- 1991-02-05 NZ NZ237025A patent/NZ237025A/en unknown
- 1991-02-05 CN CN91100705A patent/CN1029960C/zh not_active Expired - Fee Related
- 1991-02-05 ZA ZA91830A patent/ZA91830B/xx unknown
- 1991-02-05 MY MYPI91000171A patent/MY105293A/en unknown
- 1991-02-05 JP JP3014569A patent/JPH0768214B2/ja not_active Expired - Fee Related
- 1991-02-05 AU AU70293/91A patent/AU626490B2/en not_active Ceased
- 1991-02-05 IE IE37291A patent/IE63836B1/en not_active IP Right Cessation
- 1991-02-06 KR KR1019910002022A patent/KR930011041B1/ko not_active IP Right Cessation
- 1991-02-06 DE DE9101346U patent/DE9101346U1/de not_active Expired - Lifetime
- 1991-02-06 EG EG7291A patent/EG19643A/xx active
- 1991-02-06 BR BR919100490A patent/BR9100490A/pt not_active Application Discontinuation
1992
- 1992-08-05 FI FI923527A patent/FI94957C/fi active
- 1992-08-05 NO NO923081A patent/NO178399C/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
MY105293A (en)	1994-09-30
NO923081L (no)	1992-08-05
EP0441506A2 (en)	1991-08-14
FI94957B (fi)	1995-08-15
US5356905A (en)	1994-10-18
CN1053923A (zh)	1991-08-21
CA2035653C (en)	1999-12-21
KR910015568A (ko)	1991-09-30
DE69102893T2 (de)	1994-11-03
PT96664B (pt)	1998-07-31
CN1029960C (zh)	1995-10-11
AU7029391A (en)	1991-09-05
NO923081D0 (no)	1992-08-05
NO178399B (no)	1995-12-11
ES2056571T3 (es)	1994-10-01
MX24433A (es)	1993-05-01
SK281729B6 (sk)	2001-07-10
ZA91830B (en)	1992-09-30
NZ237025A (en)	1992-11-25
DE69102893T4 (de)	1995-08-10
FI923527A0 (fi)	1992-08-05
FI94957C (fi)	1995-11-27
IE910372A1 (en)	1991-08-14
IL97100A0 (en)	1992-03-29
CA2035653A1 (en)	1991-08-07
JPH0768214B2 (ja)	1995-07-26
EG19643A (en)	1995-09-30
KR930011041B1 (ko)	1993-11-20
HU222726B1 (hu)	2003-09-29
IE63836B1 (en)	1995-06-14
RU2099339C1 (ru)	1997-12-20
EP0441506B1 (en)	1994-07-20
FI923527A (fi)	1992-08-05
ATE108787T1 (de)	1994-08-15
PH31061A (en)	1998-02-05
BR9100490A (pt)	1991-10-29
PT96664A (pt)	1991-10-31
PL164866B1 (pl)	1994-10-31
DK0441506T3 (da)	1994-09-05
IL97100A (en)	1996-06-18
DE69102893D1 (de)	1994-08-25
WO1991012005A1 (en)	1991-08-22
AU626490B2 (en)	1992-07-30
EP0441506A3 (en)	1991-11-21
CZ286218B6 (cs)	2000-02-16
JPH04211058A (ja)	1992-08-03
DE9101346U1 (de)	1991-06-06
CS25091A3 (en)	1991-09-15
PL288949A1 (en)	1991-07-29

Publication	Publication Date	Title
NO178399C (no)	1996-03-20	Analogifremgangsmåte for fremstilling av terapeutisk aktive 3-piperidino-4-hydroksykromanderivater og analoger derav
MD1761B2 (ro)	2001-10-31	Eteri de 2,6-dihidroxipiridină, procedeu de preparare a lor, compoziţie erbicidă şi metodă de combatere a creşterii plantelor indezirabile
JPS5210105A (en)	1977-01-26	Moving coild cartidge
HUT62581A (en)	1993-05-28	Process for producing pipeidine derivatives and pharmaceutical compositions comprising such compounds
HRP960369B1 (en)	2009-05-31	Process for the preparation of epoxide
SE7906681L (sv)	1980-02-12	Ftalazonderivat
IT1160387B (it)	1987-03-11	Derivato isossazolico, ad attivita' terapeutica
NZ332245A (en)	2000-03-27	Substituted benzo-oxazolol carboxylic acid derivatives, process for their production and medicaments containing them
JPS51143618A (en)	1976-12-10	A process for preparing novel nitroso compounds
JPS5432480A (en)	1979-03-09	Novel preparation of piperidine derivatives
JPS52105141A (en)	1977-09-03	Preparation of perfluorononenyloxybenzoic acid
JPS54128584A (en)	1979-10-05	Novel 3,4-dihydrocarbostyril derivative
JPS5368790A (en)	1978-06-19	Preparation of 1-(2'-tetrahydrofuryl)-5-fluorouracil
ES8606368A1 (es)	1986-04-01	Un procedimiento para producir un derivado de bencil-fosfi- nato etilico
JPS51133298A (en)	1976-11-18	A process for preparing novel penicillins
JPS51125396A (en)	1976-11-01	A process for preparing diphenylfuro (3.2-c) pyrazol derivatives
JPS5368791A (en)	1978-06-19	Preparation of 1-(2'-tetrahydrofuryl)-5-fluorouracil
JPS51136682A (en)	1976-11-26	Process for preparing 5-alkanoylcarbostyril derivatives.
JPS5422391A (en)	1979-02-20	Preparation of novel 7alpha-methoxycephalosporins
JPS51128493A (en)	1976-11-09	A process for preparing optically active amino acids
ES8205788A1 (es)	1982-08-16	Procedimiento de preparar derivados del acido nicotinico
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