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NO176758C - Analogous Process for Preparing Therapeutically Useful Tetrazolyl-Biphenylyl Methyl-Pyrimidines - Google Patents

Analogous Process for Preparing Therapeutically Useful Tetrazolyl-Biphenylyl Methyl-Pyrimidines

Info

Publication number
NO176758C
NO176758C NO904511A NO904511A NO176758C NO 176758 C NO176758 C NO 176758C NO 904511 A NO904511 A NO 904511A NO 904511 A NO904511 A NO 904511A NO 176758 C NO176758 C NO 176758C
Authority
NO
Norway
Prior art keywords
pyrimidines
tetrazolyl
therapeutically useful
analogous process
preparing therapeutically
Prior art date
Application number
NO904511A
Other languages
Norwegian (no)
Other versions
NO904511L (en
NO176758B (en
NO904511D0 (en
Inventor
Peter Herold
Peter Buhlmayer
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO904511D0 publication Critical patent/NO904511D0/en
Publication of NO904511L publication Critical patent/NO904511L/en
Publication of NO176758B publication Critical patent/NO176758B/en
Publication of NO176758C publication Critical patent/NO176758C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO904511A 1989-10-19 1990-10-18 Analogous Process for Preparing Therapeutically Useful Tetrazolyl-Biphenylyl Methyl-Pyrimidines NO176758C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH379989 1989-10-19

Publications (4)

Publication Number Publication Date
NO904511D0 NO904511D0 (en) 1990-10-18
NO904511L NO904511L (en) 1991-04-22
NO176758B NO176758B (en) 1995-02-13
NO176758C true NO176758C (en) 1995-05-24

Family

ID=4263704

Family Applications (1)

Application Number Title Priority Date Filing Date
NO904511A NO176758C (en) 1989-10-19 1990-10-18 Analogous Process for Preparing Therapeutically Useful Tetrazolyl-Biphenylyl Methyl-Pyrimidines

Country Status (14)

Country Link
EP (1) EP0424317A3 (en)
JP (1) JPH03133964A (en)
KR (1) KR910007889A (en)
AU (1) AU638496B2 (en)
CA (1) CA2027839A1 (en)
FI (1) FI93957C (en)
HU (1) HUT55383A (en)
IE (1) IE903749A1 (en)
IL (1) IL96009A0 (en)
MX (1) MX22877A (en)
NO (1) NO176758C (en)
NZ (1) NZ235726A (en)
PT (1) PT95626A (en)
ZA (1) ZA908344B (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0522038A4 (en) * 1990-03-30 1993-05-26 Merck & Co. Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
US5324729A (en) * 1990-03-30 1994-06-28 Merck & Co., Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
NZ238624A (en) * 1990-06-19 1994-08-26 Meiji Seika Co Pyridine derivatives, compositions, preparations and use thereof
US5250548A (en) * 1990-09-10 1993-10-05 Abbott Laboratories Angiotensin II receptor antagonists
IL99246A0 (en) * 1990-09-10 1992-07-15 Abbott Lab Angiotensin ii receptor antagonists and pharmaceutical compositions containing them
CA2053148A1 (en) * 1990-10-16 1992-04-17 Karnail Atwal Dihydropyrimidine derivatives
US5472967A (en) * 1991-02-20 1995-12-05 Synthelabo 4-pyrimidinone derivatives their preparation and their application in therapy
FR2672892B1 (en) * 1991-02-20 1994-01-14 Synthelabo DERIVATIVES OF 4-PYRIMIDINONES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
DE4110019C2 (en) * 1991-03-27 2000-04-13 Merck Patent Gmbh Imidazopyridines, processes for their production and pharmaceutical preparations containing them
IL101860A0 (en) * 1991-05-31 1992-12-30 Ici Plc Heterocyclic derivatives
IT1250749B (en) * 1991-08-02 1995-04-21 Luso Farmaco Inst HETEROCYCLIC COMPOUNDS ACTIVATED IN II ANTAGONIST
US5234936A (en) * 1991-10-24 1993-08-10 American Home Products Corporation Pyrimidocycloalkanes as a ii antagonists
US5236925A (en) * 1991-10-24 1993-08-17 American Home Products Corporation Fused pyrimidines as angiotensin II antagonists
US5256781A (en) * 1991-10-24 1993-10-26 American Home Products Corporation Substituted quinazolines as angiotensin II antagonists
DE4221583A1 (en) 1991-11-12 1993-05-13 Bayer Ag SUBSTITUTED BIPHENYLPYRIDONE
GB9125842D0 (en) * 1991-12-04 1992-02-05 Ici Plc Heterocyclic derivatives
US5225408A (en) * 1991-12-20 1993-07-06 E. R. Squibb & Sons, Inc. Biphenyl oxadiazinone angiotensin II inhibitors
ZA931062B (en) * 1992-02-17 1993-08-17 Ciba Geigy Compositions for the treatment of glaucoma.
US5378704A (en) * 1992-04-15 1995-01-03 E. R. Squibb & Sons, Inc. Non-peptidic angiotensin-II-receptor-antagonists
US5236916A (en) * 1992-05-26 1993-08-17 E. R. Squibb & Sons, Inc. Oxadiazinone substituted indole and benzimidazole derivatives
TW348175B (en) * 1993-01-06 1998-12-21 Hoechst Ag Process for the preparation of biphenyl derivatives
WO2000027824A1 (en) * 1998-11-12 2000-05-18 Elan Pharmaceuticals Substituted pyrimidine compositions and methods of use
SE9903028D0 (en) 1999-08-27 1999-08-27 Astra Ab New use
EP1813620A4 (en) * 2004-10-08 2009-12-30 Kotobuki Pharmaceutical Co Ltd Phosphonic acid derivative and therapeutic agent for disease in which high phosphate level in blood participates
US8080571B2 (en) * 2005-04-12 2011-12-20 Vicore Pharma Ab Tricyclic angiotensin II agonists
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2624828T3 (en) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and others
US20120322819A1 (en) * 2010-02-25 2012-12-20 Kowa Company, Ltd. Compound containing a novel 4-alkoxypyrimidine structure and medicine containing same
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
EP3004138B1 (en) 2013-06-05 2024-03-13 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase c, method of making and using same
CN116134025A (en) * 2020-09-17 2023-05-16 浙江海正药业股份有限公司 Amide phosphine oxide derivative and preparation method and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles

Also Published As

Publication number Publication date
HUT55383A (en) 1991-05-28
AU638496B2 (en) 1993-07-01
IL96009A0 (en) 1991-07-18
FI93957C (en) 1995-06-26
EP0424317A2 (en) 1991-04-24
FI905124A0 (en) 1990-10-17
NO904511L (en) 1991-04-22
NZ235726A (en) 1993-09-27
JPH03133964A (en) 1991-06-07
KR910007889A (en) 1991-05-30
ZA908344B (en) 1991-06-26
NO176758B (en) 1995-02-13
AU6468090A (en) 1991-04-26
CA2027839A1 (en) 1991-04-20
MX22877A (en) 1993-12-01
NO904511D0 (en) 1990-10-18
HU906501D0 (en) 1991-04-29
IE903749A1 (en) 1991-04-24
PT95626A (en) 1991-09-13
FI93957B (en) 1995-03-15
EP0424317A3 (en) 1991-09-25

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