NO173653C - Analogifremgangsmaate for fresmstilling av terapeutisk aktive 6-benzoksazinyl-og 6-benzotianzinyl-2,3,4,5-tetrahydropyridazin-3-oner - Google Patents
Analogifremgangsmaate for fresmstilling av terapeutisk aktive 6-benzoksazinyl-og 6-benzotianzinyl-2,3,4,5-tetrahydropyridazin-3-onerInfo
- Publication number
- NO173653C NO173653C NO875358A NO875358A NO173653C NO 173653 C NO173653 C NO 173653C NO 875358 A NO875358 A NO 875358A NO 875358 A NO875358 A NO 875358A NO 173653 C NO173653 C NO 173653C
- Authority
- NO
- Norway
- Prior art keywords
- benzothianzinyl
- tetrahydropyridazin
- benzoxazinyl
- preparation
- therapeutically active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO912800A NO912800D0 (no) | 1986-12-22 | 1991-07-17 | Mellomprodukter. |
| NO922610A NO922610D0 (no) | 1986-12-22 | 1992-07-02 | Mellomprodukter |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/944,316 US4721784A (en) | 1986-12-22 | 1986-12-22 | 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones |
| US07/064,638 US4766118A (en) | 1986-12-22 | 1987-06-22 | 6-benzoxazinyl- and 6-benzothiazinyl-2,3,4,5-tetrahydropyridazin-3-ones and pharmaceutical use |
| US12514287A | 1987-12-02 | 1987-12-02 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO875358D0 NO875358D0 (no) | 1987-12-21 |
| NO875358L NO875358L (no) | 1988-06-23 |
| NO173653B NO173653B (no) | 1993-10-04 |
| NO173653C true NO173653C (no) | 1994-01-12 |
Family
ID=27370654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO875358A NO173653C (no) | 1986-12-22 | 1987-12-21 | Analogifremgangsmaate for fresmstilling av terapeutisk aktive 6-benzoksazinyl-og 6-benzotianzinyl-2,3,4,5-tetrahydropyridazin-3-oner |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0272914A3 (no) |
| KR (1) | KR880007527A (no) |
| AU (2) | AU607731B2 (no) |
| DK (1) | DK673087A (no) |
| FI (1) | FI86425C (no) |
| HU (1) | HU207314B (no) |
| IL (1) | IL84832A (no) |
| MY (2) | MY102280A (no) |
| NO (1) | NO173653C (no) |
| NZ (1) | NZ222843A (no) |
| PH (1) | PH24498A (no) |
| PT (1) | PT86453B (no) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3934436A1 (de) * | 1989-06-01 | 1991-04-18 | Thomae Gmbh Dr K | 2-hydroxy-n-propylamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| TW224941B (no) * | 1989-11-08 | 1994-06-11 | Yamanouchi Pharma Co Ltd | |
| US5221742A (en) * | 1990-12-21 | 1993-06-22 | Ortho Pharmaceutical Corporation | Process for the preparation of 6-(3,4-dihydro-3-oxo-1,4(2h)-benzoxazin-7-yl)-2,3,4,5-tetrahydropyridazin-3-ones |
| AU1493092A (en) * | 1991-04-18 | 1992-10-22 | Ortho Pharmaceutical Corporation | (+) and (-) enantiomers of 5-aliphatic-6-(benzoxazinyl- or benzothiazinyl)-2,3,4,5-tetrahydropyridazin-3-ones |
| CN1202159A (zh) * | 1995-09-22 | 1998-12-16 | 住友化学工业株式会社 | 吡嗪－2－酮衍生物,它们的应用及用于制备它们的中间体 |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| WO2005099688A2 (en) | 2004-04-07 | 2005-10-27 | Takeda Pharmaceutical Company Limited | Cyclic compounds |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| KR20080065704A (ko) | 2005-11-09 | 2008-07-14 | 콤비네이토릭스, 인코포레이티드 | 의학적 이상의 치료 방법들, 조성물들, 및 키트들 |
| US20100120694A1 (en) | 2008-06-04 | 2010-05-13 | Synergy Pharmaceuticals, Inc. | Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| US7879802B2 (en) | 2007-06-04 | 2011-02-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| MX357121B (es) | 2011-03-01 | 2018-06-27 | Synergy Pharmaceuticals Inc Star | Proceso de preparacion de agonistas c de guanilato ciclasa. |
| WO2013106547A1 (en) | 2012-01-10 | 2013-07-18 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
| US9545446B2 (en) | 2013-02-25 | 2017-01-17 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
| CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| EP3004138B1 (en) | 2013-06-05 | 2024-03-13 | Bausch Health Ireland Limited | Ultra-pure agonists of guanylate cyclase c, method of making and using same |
| JP6694385B2 (ja) | 2013-08-09 | 2020-05-13 | アーデリクス，インコーポレーテッド | リン酸塩輸送阻害のための化合物及び方法 |
| US20200368223A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Methods for inhibiting phosphate transport |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2035749A1 (no) * | 1969-02-06 | 1970-12-24 | Bellon Labor Sa Roger | |
| FR2588868B1 (fr) * | 1985-10-21 | 1988-11-10 | Negma Laboratoires | Acyl-7 benzoxazinones et leurs derives, procede pour les obtenir et compositions pharmaceutiques les contenant |
| TW224941B (no) * | 1989-11-08 | 1994-06-11 | Yamanouchi Pharma Co Ltd |
-
1987
- 1987-12-08 NZ NZ222843A patent/NZ222843A/xx unknown
- 1987-12-15 IL IL84832A patent/IL84832A/xx unknown
- 1987-12-20 KR KR870014668A patent/KR880007527A/ko not_active Application Discontinuation
- 1987-12-21 FI FI875619A patent/FI86425C/fi not_active IP Right Cessation
- 1987-12-21 NO NO875358A patent/NO173653C/no unknown
- 1987-12-21 DK DK673087A patent/DK673087A/da not_active Application Discontinuation
- 1987-12-21 PH PH36276A patent/PH24498A/en unknown
- 1987-12-22 HU HU875959A patent/HU207314B/hu not_active IP Right Cessation
- 1987-12-22 PT PT86453A patent/PT86453B/pt not_active IP Right Cessation
- 1987-12-22 EP EP87311286A patent/EP0272914A3/en not_active Withdrawn
- 1987-12-22 AU AU82932/87A patent/AU607731B2/en not_active Ceased
- 1987-12-23 MY MYPI87003247A patent/MY102280A/en unknown
- 1987-12-23 MY MYPI91001412A patent/MY106781A/en unknown
-
1990
- 1990-12-14 AU AU68086/90A patent/AU633666B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| MY102280A (en) | 1992-05-15 |
| IL84832A (en) | 1993-01-14 |
| KR880007527A (ko) | 1988-08-27 |
| PT86453B (pt) | 1990-11-20 |
| AU8293287A (en) | 1988-06-23 |
| AU633666B2 (en) | 1993-02-04 |
| FI875619A (fi) | 1988-06-23 |
| EP0272914A3 (en) | 1990-04-04 |
| HU207314B (en) | 1993-03-29 |
| FI875619A0 (fi) | 1987-12-21 |
| FI86425C (fi) | 1992-08-25 |
| DK673087A (da) | 1988-06-23 |
| DK673087D0 (da) | 1987-12-21 |
| HUT48624A (en) | 1989-06-28 |
| PT86453A (en) | 1988-01-01 |
| EP0272914A2 (en) | 1988-06-29 |
| AU6808690A (en) | 1991-04-26 |
| PH24498A (en) | 1990-07-18 |
| NO875358D0 (no) | 1987-12-21 |
| NZ222843A (en) | 1989-10-27 |
| AU607731B2 (en) | 1991-03-14 |
| NO875358L (no) | 1988-06-23 |
| FI86425B (fi) | 1992-05-15 |
| NO173653B (no) | 1993-10-04 |
| IL84832A0 (en) | 1988-06-30 |
| MY106781A (en) | 1995-07-31 |
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