NO144925C - ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BIS (2-METHYL-3-HYDROXY-4-HYDROXYMETHYL-5-MERCAPTOMETHYL-PYRIDINIUM) -ETHANE-1,2-DISULPHONATE - Google Patents

ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BIS (2-METHYL-3-HYDROXY-4-HYDROXYMETHYL-5-MERCAPTOMETHYL-PYRIDINIUM) -ETHANE-1,2-DISULPHONATE

Info

Publication number: NO144925C
Authority: NO; Norway
Prior art keywords: disulphonate; mercaptomethyl; pyridinium; ethane; hydroxymethyl
Prior art date: 1975-05-09

Application number

NO761367A

Other languages

Norwegian (no)

Other versions

NO761367L (en

NO144925B (en

Inventor

Conrad Peter Dorn

Howard Jones

David Penman Jacobus

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-05-09

Filing date

1976-04-22

Publication date

1981-12-09

1976-04-22 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1976-11-10 Publication of NO761367L publication Critical patent/NO761367L/no

1981-08-31 Publication of NO144925B publication Critical patent/NO144925B/en

1981-12-09 Publication of NO144925C publication Critical patent/NO144925C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
- C07D213/67—2-Methyl-3-hydroxy-4,5-bis(hydroxy-methyl)pyridine, i.e. pyridoxine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO761367A 1975-05-09 1976-04-22 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BIS (2-METHYL-3-HYDROXY-4-HYDROXYMETHYL-5-MERCAPTOMETHYL-PYRIDINIUM) -ETHANE-1,2-DISULPHONATE NO144925C (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US57605575A	1975-05-09	1975-05-09

Publications (3)

Publication Number	Publication Date
NO761367L NO761367L (en)	1976-11-10
NO144925B NO144925B (en)	1981-08-31
NO144925C true NO144925C (en)	1981-12-09

Family

ID=24302783

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO761367A NO144925C (en)	1975-05-09	1976-04-22	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BIS (2-METHYL-3-HYDROXY-4-HYDROXYMETHYL-5-MERCAPTOMETHYL-PYRIDINIUM) -ETHANE-1,2-DISULPHONATE

Country Status (29)

Country	Link
JP (1)	JPS51138684A (en)
AR (1)	AR210883A1 (en)
AT (1)	AT348691B (en)
AU (1)	AU1342876A (en)
BE (1)	BE841593A (en)
BG (1)	BG25218A3 (en)
CA (1)	CA1088542A (en)
CH (1)	CH625222A5 (en)
CS (1)	CS189003B2 (en)
DD (1)	DD125482A5 (en)
DE (1)	DE2620325C3 (en)
DK (1)	DK143335C (en)
ES (1)	ES447717A1 (en)
FI (1)	FI61881C (en)
FR (1)	FR2310130A1 (en)
GB (1)	GB1490688A (en)
GR (1)	GR59817B (en)
HU (1)	HU172048B (en)
IE (1)	IE43030B1 (en)
IL (1)	IL49466A (en)
LU (1)	LU74892A1 (en)
NL (1)	NL7604285A (en)
NO (1)	NO144925C (en)
NZ (1)	NZ180691A (en)
PL (1)	PL100306B1 (en)
PT (1)	PT65061B (en)
RO (1)	RO68526A (en)
SE (1)	SE427033B (en)
ZA (1)	ZA762750B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1695428C3 (en) *	1967-06-08	1978-10-05	Merck Patent Gmbh, 6100 Darmstadt	Derivatives of 5-mercaptopyridoxine and process for their preparation
US3852454A (en) *	1973-06-15	1974-12-03	Merck & Co Inc	Treatment of rheumatoid arthritis

1976
- 1976-04-21 SE SE7604580A patent/SE427033B/en not_active IP Right Cessation
- 1976-04-21 DK DK179376A patent/DK143335C/en not_active IP Right Cessation
- 1976-04-21 FI FI761084A patent/FI61881C/en not_active IP Right Cessation
- 1976-04-22 NO NO761367A patent/NO144925C/en unknown
- 1976-04-22 NL NL7604285A patent/NL7604285A/en not_active Application Discontinuation
- 1976-04-24 RO RO7685792A patent/RO68526A/en unknown
- 1976-04-26 CH CH521976A patent/CH625222A5/en not_active IP Right Cessation
- 1976-04-26 NZ NZ180691A patent/NZ180691A/en unknown
- 1976-04-26 IL IL49466A patent/IL49466A/en unknown
- 1976-04-27 AR AR263046A patent/AR210883A1/en active
- 1976-04-28 AU AU13428/76A patent/AU1342876A/en not_active Expired
- 1976-04-29 GR GR50620A patent/GR59817B/en unknown
- 1976-04-30 PT PT65061A patent/PT65061B/en unknown
- 1976-05-04 BG BG033100A patent/BG25218A3/en unknown
- 1976-05-04 GB GB18196/76A patent/GB1490688A/en not_active Expired
- 1976-05-04 CA CA251,741A patent/CA1088542A/en not_active Expired
- 1976-05-05 FR FR7613351A patent/FR2310130A1/en active Granted
- 1976-05-06 PL PL1976189342A patent/PL100306B1/en unknown
- 1976-05-06 LU LU74892A patent/LU74892A1/xx unknown
- 1976-05-06 DD DD192709A patent/DD125482A5/xx unknown
- 1976-05-07 IE IE990/76A patent/IE43030B1/en unknown
- 1976-05-07 ES ES447717A patent/ES447717A1/en not_active Expired
- 1976-05-07 AT AT335676A patent/AT348691B/en not_active IP Right Cessation
- 1976-05-07 DE DE2620325A patent/DE2620325C3/en not_active Expired
- 1976-05-07 ZA ZA762750A patent/ZA762750B/en unknown
- 1976-05-07 HU HU76ME00001974A patent/HU172048B/en unknown
- 1976-05-07 BE BE166849A patent/BE841593A/en unknown
- 1976-05-07 CS CS763063A patent/CS189003B2/en unknown
- 1976-05-08 JP JP51051720A patent/JPS51138684A/en active Pending

Also Published As

Publication number	Publication date
DE2620325B2 (en)	1978-11-16
NO761367L (en)	1976-11-10
PT65061B (en)	1977-04-03
CA1088542A (en)	1980-10-28
DK143335B (en)	1981-08-10
ZA762750B (en)	1977-12-28
DD125482A5 (en)	1977-04-20
NZ180691A (en)	1978-07-28
DK143335C (en)	1981-12-14
JPS51138684A (en)	1976-11-30
IL49466A0 (en)	1976-06-30
NL7604285A (en)	1976-11-11
HU172048B (en)	1978-05-28
ES447717A1 (en)	1978-04-01
BE841593A (en)	1976-11-08
FI61881C (en)	1982-10-11
IL49466A (en)	1979-05-31
CS189003B2 (en)	1979-03-30
AT348691B (en)	1979-02-26
DE2620325A1 (en)	1976-11-18
DE2620325C3 (en)	1979-08-02
FI61881B (en)	1982-06-30
DK179376A (en)	1976-11-10
SE7604580L (en)	1976-11-10
SE427033B (en)	1983-02-28
RO68526A (en)	1981-08-30
AU1342876A (en)	1977-11-03
AR210883A1 (en)	1977-09-30
BG25218A3 (en)	1978-08-10
CH625222A5 (en)	1981-09-15
NO144925B (en)	1981-08-31
ATA335676A (en)	1978-07-15
GR59817B (en)	1978-03-02
LU74892A1 (en)	1977-02-11
IE43030L (en)	1976-11-09
FI761084A (en)	1976-11-10
PT65061A (en)	1976-05-01
PL100306B1 (en)	1978-09-30
FR2310130B1 (en)	1979-09-28
FR2310130A1 (en)	1976-12-03
IE43030B1 (en)	1980-12-03
GB1490688A (en)	1977-11-02

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