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NL8000869A - Cyanoguanidine-derivaten en werkwijze voor de bereiding daarvan. - Google Patents

Cyanoguanidine-derivaten en werkwijze voor de bereiding daarvan. Download PDF

Info

Publication number
NL8000869A
NL8000869A NL8000869A NL8000869A NL8000869A NL 8000869 A NL8000869 A NL 8000869A NL 8000869 A NL8000869 A NL 8000869A NL 8000869 A NL8000869 A NL 8000869A NL 8000869 A NL8000869 A NL 8000869A
Authority
NL
Netherlands
Prior art keywords
group
formula
carbon atoms
addition salt
acid addition
Prior art date
Application number
NL8000869A
Other languages
English (en)
Dutch (nl)
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1598979A external-priority patent/JPS568357A/ja
Priority claimed from JP54015990A external-priority patent/JPS6016940B2/ja
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of NL8000869A publication Critical patent/NL8000869A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
NL8000869A 1979-02-16 1980-02-12 Cyanoguanidine-derivaten en werkwijze voor de bereiding daarvan. NL8000869A (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP1598979 1979-02-16
JP1599079 1979-02-16
JP1598979A JPS568357A (en) 1979-02-16 1979-02-16 Cyanoguanidine derivative and its production
JP54015990A JPS6016940B2 (ja) 1979-02-16 1979-02-16 シアノグアニジン誘導体およびその製造法

Publications (1)

Publication Number Publication Date
NL8000869A true NL8000869A (nl) 1980-08-19

Family

ID=26352224

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8000869A NL8000869A (nl) 1979-02-16 1980-02-12 Cyanoguanidine-derivaten en werkwijze voor de bereiding daarvan.

Country Status (9)

Country Link
US (5) US4287346A (sv)
CA (1) CA1145751A (sv)
CH (1) CH641772A5 (sv)
DE (1) DE3005786A1 (sv)
FR (1) FR2453155A1 (sv)
GB (2) GB2107306B (sv)
IT (1) IT1141214B (sv)
NL (1) NL8000869A (sv)
SE (2) SE8001216L (sv)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8000869A (nl) 1979-02-16 1980-08-19 Eisai Co Ltd Cyanoguanidine-derivaten en werkwijze voor de bereiding daarvan.
EP0072926B1 (de) * 1981-08-19 1986-09-24 MERCK PATENT GmbH 2-Aryl-imidazopyridine
IE54196B1 (en) * 1981-09-10 1989-07-19 Leo Pharm Prod Ltd Chemical compounds
IT1190793B (it) * 1982-04-27 1988-02-24 Magis Farmaceutici Composti attivi nel trattamento dell'ulcera e sintomi allergici della pelle
US4496573A (en) * 1982-08-24 1985-01-29 William H. Rorer, Inc. 1-Pyridylmethyl-3-acyl guanidines
US4529723A (en) * 1983-04-29 1985-07-16 William H. Rorer, Inc. Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use
US4689348A (en) * 1984-08-17 1987-08-25 Dow Chemical Company Cyanoguanidines useful as animal growth promoting agents
US4661520A (en) * 1984-08-17 1987-04-28 The Dow Chemical Company Cyanoguanidine useful as an animal growth promoting agent
US4921939A (en) * 1985-03-19 1990-05-01 Universite Claude Bernard -Lyon 1 Sweetening agents
FR2579201B1 (fr) * 1985-03-19 1987-05-07 Bernard Lyon I Universite Clau Composes chimiques perfectionnes, utilisation comme agents edulcorants et compositions contenant de tels agents
FR2579202B1 (fr) * 1985-03-19 1988-04-29 Univ Claude Bernard Lyon Nouveaux composes chimiques, utilisation comme agents edulcorants et compositions contenant de tels agents
US4963573A (en) * 1985-11-04 1990-10-16 Janssen Pharmaceutica N.V. [[[(3-pyridinyl)methylen]amino]oxy]alkanoic acids and esters
US4746671A (en) * 1985-11-04 1988-05-24 Janssen Pharmaceutica N.V. Pharmaceutical use of [[[(3-pyridinyl)methylen]amino]oxy]alkanoic acids and esters
US4895840A (en) * 1987-06-10 1990-01-23 A. H. Robins Company, Incorporated N-(aryl-,aryloxy-,arylthio-arylsulfinyl-and arylsulfonyl-)alkyl-N,N'-(or n'n')alkylaminoalkyl ureas and cyanoguanidines
GB8722776D0 (en) * 1987-09-28 1987-11-04 Smith Kline French Lab Chemical compounds
US4900740A (en) * 1987-10-02 1990-02-13 The Nutrasweet Company N,N'-disubstituted guanidines containing a carboxyl or a tetrazolyl moiety
FR2624699B1 (fr) * 1987-12-18 1990-04-13 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-glycine ou beta-alanine utiles comme agents edulcorants
US5272164A (en) * 1988-12-27 1993-12-21 Kirin Beer Kabushiki Kaisha Carboximidamide derivatives
JPH0662567B2 (ja) * 1988-12-27 1994-08-17 麒麟麦酒株式会社 ピリジンカルボキシイミダミド誘導体、その製造中間体、製造法および用途
FI95244C (sv) * 1988-12-27 1996-01-10 Kirin Brewery Analogiförfarande för framställning av som läkemedel användbara nya karboxi-imidamidderivat eller dess farmaceutiskt lämpliga syra-additionssalter
IE911168A1 (en) * 1990-04-13 1991-10-23 Takeda Chemical Industries Ltd Novel intermediates for preparing guanidine derivatives,¹their preparation and use
AU4530693A (en) * 1992-08-13 1994-03-15 Upjohn Company, The Cyanoguanidines as potassium channel blockers
WO1994029280A1 (en) * 1993-06-11 1994-12-22 The Upjohn Company Pyrimidine cyanoguanidines as k-channel blockers
US7700561B2 (en) * 2002-02-22 2010-04-20 Shire Llc Abuse-resistant amphetamine prodrugs

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3128280A (en) * 1959-10-23 1964-04-07 Searle & Co 1-(alkoxylated/halogenated phenyl)-3-pyridylmethylureas
US3028391A (en) * 1960-03-30 1962-04-03 Searle & Co 1-alkyl-3-(alpha-phenyl-4-pyridylmethyl) ureas and thioureas
GB1397436A (en) * 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
GB1421792A (en) * 1973-05-17 1976-01-21 Smith Kline French Lab Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them
US4154838A (en) * 1975-07-31 1979-05-15 Smith Kline & French Laboratories Limited Alkoxy pyridine
GB1564502A (en) * 1975-07-31 1980-04-10 Smith Kline French Lab Guanidines thioureas and 1,1-diamino-2-nitroethylene derivatives
JPS5444660A (en) * 1977-08-29 1979-04-09 Yamanouchi Pharmaceut Co Ltd Heterocyclic compound and its preparation
NL8000869A (nl) 1979-02-16 1980-08-19 Eisai Co Ltd Cyanoguanidine-derivaten en werkwijze voor de bereiding daarvan.

Also Published As

Publication number Publication date
GB2046736A (en) 1980-11-19
US4327217A (en) 1982-04-27
CA1145751A (en) 1983-05-03
US4426521A (en) 1984-01-17
CH641772A5 (de) 1984-03-15
FR2453155A1 (fr) 1980-10-31
IT1141214B (it) 1986-10-01
GB2046736B (en) 1983-05-18
IT8019938A0 (it) 1980-02-15
FR2453155B1 (sv) 1983-07-08
SE8403871L (sv) 1984-07-26
US4363921A (en) 1982-12-14
US4396764A (en) 1983-08-02
SE8403871D0 (sv) 1984-07-26
GB2107306B (en) 1983-09-01
US4287346A (en) 1981-09-01
SE8001216L (sv) 1980-08-17
DE3005786A1 (de) 1980-08-28
GB2107306A (en) 1983-04-27

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BV The patent application has lapsed