NL2000336A1 - Spirocyclische derivaten. - Google Patents

Spirocyclische derivaten.

Info

Publication number: NL2000336A1
Authority: NL; Netherlands
Prior art keywords: spirocyclic derivatives; spirocyclic; derivatives
Prior art date: 2005-12-02

Application number

NL2000336A

Other languages

English (en)

Other versions

NL2000336C2 (nl

Inventor

David James Rawson

Nigel Alan Swain

Original Assignee

Pfizer Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-12-02

Filing date

2006-11-27

Publication date

2007-06-05

2006-11-27 Application filed by Pfizer Ltd filed Critical Pfizer Ltd

2007-06-05 Publication of NL2000336A1 publication Critical patent/NL2000336A1/nl

2007-08-07 Application granted granted Critical

2007-08-07 Publication of NL2000336C2 publication Critical patent/NL2000336C2/nl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/80—Oxygen atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Neurology (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Virology (AREA)
Orthopedic Medicine & Surgery (AREA)
AIDS & HIV (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NL2000336A 2005-12-02 2006-11-27 Spirocyclische derivaten. NL2000336C2 (nl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US74185405P	2005-12-02	2005-12-02
US74185405		2005-12-02
US79118606P	2006-04-10	2006-04-10
US79118606		2006-04-10

Publications (2)

Publication Number	Publication Date
NL2000336A1 true NL2000336A1 (nl)	2007-06-05
NL2000336C2 NL2000336C2 (nl)	2007-08-07

Family

ID=37882213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL2000336A NL2000336C2 (nl)	2005-12-02	2006-11-27	Spirocyclische derivaten.

Country Status (22)

Country	Link
US (1)	US7507742B2 (nl)
EP (1)	EP1957467A2 (nl)
JP (1)	JP2009517453A (nl)
KR (1)	KR101009554B1 (nl)
AP (1)	AP2008004470A0 (nl)
AR (1)	AR058266A1 (nl)
AU (1)	AU2006321349A1 (nl)
BR (1)	BRPI0619126A2 (nl)
CA (1)	CA2631535C (nl)
CR (1)	CR10039A (nl)
EA (1)	EA200801145A1 (nl)
EC (1)	ECSP088484A (nl)
GT (1)	GT200600494A (nl)
MA (1)	MA30014B1 (nl)
ME (1)	MEP0408A (nl)
NL (1)	NL2000336C2 (nl)
NO (1)	NO20082077L (nl)
PE (1)	PE20071087A1 (nl)
RS (1)	RS20080233A (nl)
TW (1)	TW200732307A (nl)
UY (1)	UY29979A1 (nl)
WO (1)	WO2007063391A2 (nl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR9710536A (pt)	1996-07-24	1999-08-17	Warner Lambert Co	Isobutilgaba e seus derivados para o tratamento da dor
CA2606353C (en) *	2005-04-28	2011-11-22	Pfizer Limited	Alpha-methyl amino acid derivatives
ES2533206T3 (es) *	2007-03-27	2015-04-08	Omeros Corporation	Inhibidores de PDE7 para uso en el tratamiento de trastornos del movimiento
US8637528B2 (en)	2007-03-27	2014-01-28	Omeros Corporation	Use of PDE7 inhibitors for the treatment of movement disorders
CA2687944A1 (en) *	2007-05-24	2008-11-27	Pfizer Limited	Spirocyclic quinazoline derivatives and their use as pde7 inhibitors
SG157299A1 (en) *	2008-05-09	2009-12-29	Agency Science Tech & Res	Diagnosis and treatment of kawasaki disease
DK2433124T3 (en) *	2009-05-19	2017-06-19	Vivia Biotech Sl	PROCEDURES FOR PROVIDING PERSONALIZED MEDICAL EX VIVO TESTS FOR HEMATOLOGICAL NEOPLASMS
KR20130124333A (ko)	2010-11-08	2013-11-13	오메로스 코포레이션	Pde7 억제제를 사용한 중독 및 충동-조절 장애의 치료
US9220715B2 (en)	2010-11-08	2015-12-29	Omeros Corporation	Treatment of addiction and impulse-control disorders using PDE7 inhibitors
CU24152B1 (es)	2010-12-20	2016-02-29	Irm Llc	1,2 oxazol-8-azabiciclo[3,2,1]octano 8 il como moduladores de fxr
KR102640696B1 (ko) *	2017-07-12	2024-02-27	다트 뉴로사이언스, 엘엘씨	Pde7 억제제로서 치환된 벤즈옥사졸 및 벤조푸란 화합물
IL318817A (en)	2022-08-18	2025-04-01	Mitodicure Gmbh	Use of a therapeutic agent with PHOSPHODIESTERASE-7 inhibitory activity for the treatment and prevention of diseases associated with chronic fatigue, exhaustion and/or exercise intolerance

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2003531619A (ja)	2000-04-28	2003-10-28	メルクパテントゲゼルシャフトミットベシュレンクテルハフトング	ｃＡＭＰホスホジエステラーゼ７型（ＰＤＥ７ａ３）のスプライス変異体
AP1699A (en)	2001-03-21	2006-12-26	Warner Lambert Co	New spirotricyclic derivatives and their use as phosphodiesterase-7 inhibitors
EP1400244A1 (en)	2002-09-17	2004-03-24	Warner-Lambert Company LLC	New spirocondensed quinazolinones and their use as phosphodiesterase inhibitors
WO2006092692A1 (en) *	2005-03-01	2006-09-08	Pfizer Limited	Use of combinations of pde7 inhibitors and alpha-2-delty ligands for the treatment of neuropathic pain
US20090111837A1 (en) *	2005-03-01	2009-04-30	Peter Cox	Use of pde7 inhibitors for the treatment of neuropathic pain

2006
- 2006-11-23 BR BRPI0619126-6A patent/BRPI0619126A2/pt not_active Application Discontinuation
- 2006-11-23 AP AP2008004470A patent/AP2008004470A0/xx unknown
- 2006-11-23 AU AU2006321349A patent/AU2006321349A1/en not_active Abandoned
- 2006-11-23 ME MEP-04/08A patent/MEP0408A/xx unknown
- 2006-11-23 WO PCT/IB2006/003388 patent/WO2007063391A2/en active Application Filing
- 2006-11-23 CA CA2631535A patent/CA2631535C/en not_active Expired - Fee Related
- 2006-11-23 EA EA200801145A patent/EA200801145A1/xx unknown
- 2006-11-23 EP EP06820991A patent/EP1957467A2/en not_active Withdrawn
- 2006-11-23 RS RSP-2008/0233A patent/RS20080233A/sr unknown
- 2006-11-23 KR KR1020087013205A patent/KR101009554B1/ko not_active Expired - Fee Related
- 2006-11-23 JP JP2008542855A patent/JP2009517453A/ja not_active Withdrawn
- 2006-11-27 NL NL2000336A patent/NL2000336C2/nl not_active IP Right Cessation
- 2006-11-29 GT GT200600494A patent/GT200600494A/es unknown
- 2006-11-29 PE PE2006001519A patent/PE20071087A1/es not_active Application Discontinuation
- 2006-11-30 UY UY29979A patent/UY29979A1/es not_active Application Discontinuation
- 2006-12-01 US US11/565,953 patent/US7507742B2/en not_active Expired - Fee Related
- 2006-12-01 TW TW095144665A patent/TW200732307A/zh unknown
- 2006-12-01 AR ARP060105332A patent/AR058266A1/es unknown
2008
- 2008-05-02 NO NO20082077A patent/NO20082077L/no not_active Application Discontinuation
- 2008-05-29 EC EC2008008484A patent/ECSP088484A/es unknown
- 2008-05-30 CR CR10039A patent/CR10039A/es not_active Application Discontinuation
- 2008-06-02 MA MA30981A patent/MA30014B1/fr unknown

Also Published As

Publication number	Publication date
RS20080233A (en)	2009-07-15
EP1957467A2 (en)	2008-08-20
KR101009554B1 (ko)	2011-01-18
US7507742B2 (en)	2009-03-24
BRPI0619126A2 (pt)	2011-09-13
PE20071087A1 (es)	2007-12-29
AR058266A1 (es)	2008-01-30
TW200732307A (en)	2007-09-01
UY29979A1 (es)	2007-06-29
AU2006321349A1 (en)	2007-06-07
US20070129388A1 (en)	2007-06-07
KR20080059338A (ko)	2008-06-26
ECSP088484A (es)	2008-06-30
MA30014B1 (fr)	2008-12-01
EA200801145A1 (ru)	2008-10-30
NO20082077L (no)	2008-06-04
NL2000336C2 (nl)	2007-08-07
AP2008004470A0 (en)	2008-06-30
MEP0408A (xx)	2010-02-10
JP2009517453A (ja)	2009-04-30
CA2631535A1 (en)	2007-06-07
WO2007063391A2 (en)	2007-06-07
CA2631535C (en)	2010-07-27
WO2007063391A3 (en)	2007-09-13
GT200600494A (es)	2007-07-06
CR10039A (es)	2008-07-10

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DK1971588T3 (da)	2012-10-22	Tiglien-3-onderivater
NL1032046A1 (nl)	2007-01-02	Prostaglandinederivaten.
NL2000937A1 (nl)	2008-01-11	Piperidinederivaten.
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DE602006019209D1 (de)	2011-02-10	Fluoroalkylpyrrolidin-derivate
ES1061250Y (es)	2006-05-16	Conjunto garrafa-tapon.
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ES1059608Y (es)	2005-08-16	Percha-soporte.
ES1059992Y (es)	2005-10-16	Marco-estuche.
ES1059785Y (es)	2005-09-16	Caja-asiento.

Legal Events

Date	Code	Title	Description
2007-08-01	AD1A	A request for search or an international type search has been filed
2007-08-01	RD2N	Patents in respect of which a decision has been taken or a report has been made (novelty report)	Effective date: 20070605
2007-10-01	PD2B	A search report has been drawn up
2010-06-23	V1	Lapsed because of non-payment of the annual fee	Effective date: 20100601