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NL193542B - Process for preparing a salt of the methyl ester of Ó-L-aspartyl-L-phenylalanine. - Google Patents

Process for preparing a salt of the methyl ester of Ó-L-aspartyl-L-phenylalanine.

Info

Publication number
NL193542B
NL193542B NL8500325A NL8500325A NL193542B NL 193542 B NL193542 B NL 193542B NL 8500325 A NL8500325 A NL 8500325A NL 8500325 A NL8500325 A NL 8500325A NL 193542 B NL193542 B NL 193542B
Authority
NL
Netherlands
Prior art keywords
aspartyl
phenylalanine
salt
preparing
methyl ester
Prior art date
Application number
NL8500325A
Other languages
Dutch (nl)
Other versions
NL193542C (en
NL8500325A (en
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of NL8500325A publication Critical patent/NL8500325A/en
Publication of NL193542B publication Critical patent/NL193542B/en
Application granted granted Critical
Publication of NL193542C publication Critical patent/NL193542C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
NL8500325A 1984-02-21 1985-02-06 Process for preparing a salt of the methyl ester of Ó-L-aspartyl-L-phenylalanine. NL193542C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3098784 1984-02-21
JP59030987A JPS60174799A (en) 1984-02-21 1984-02-21 Preparation of alpha-l-aspartyl-l-phenylalaninemethyl ester

Publications (3)

Publication Number Publication Date
NL8500325A NL8500325A (en) 1985-09-16
NL193542B true NL193542B (en) 1999-09-01
NL193542C NL193542C (en) 2000-01-04

Family

ID=12318969

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8500325A NL193542C (en) 1984-02-21 1985-02-06 Process for preparing a salt of the methyl ester of Ó-L-aspartyl-L-phenylalanine.

Country Status (5)

Country Link
US (1) US4634790A (en)
JP (1) JPS60174799A (en)
FR (1) FR2559773B1 (en)
IT (1) IT1183336B (en)
NL (1) NL193542C (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8703487A1 (en) * 1984-12-27 1987-03-01 Mitsui Toatsu Chemicals Process for the preparation of alpha-L-aspartyl-L-phenylalanine methyl ester.
AU561384B2 (en) * 1985-03-26 1987-05-07 Mitsui Toatsu Chemicals Inc. Preparation of -l-aspartyl-l-phenylalanine methyl ester or hydrochloride thereof
AU586669B2 (en) * 1985-03-29 1989-07-20 Mitsui Toatsu Chemicals Inc. Preparation process of ```-L-aspartyl-L-phenylalanine methyl ester or hydrochloride thereof
JPH0751596B2 (en) * 1985-04-01 1995-06-05 三井東圧化学株式会社 Process for producing α-L-aspartyl-L-phenylalanine methyl ester or its hydrochloride
EP0220028B1 (en) * 1985-10-11 1990-02-07 Ajinomoto Co., Inc. Process for producing l-aspartyl-l-phenylalanine and its diketopiperazine
DE3780585T2 (en) * 1986-12-05 1993-03-18 Mitsui Toatsu Chemicals PRODUCTION OF ALPHA-L-ASPARTYL-L-PHENYLALANINE METHYL ESTERS OR THEIR HYDROHALIDES.
JPH0832719B2 (en) * 1986-12-19 1996-03-29 三井東圧化学株式会社 Method for producing α-L-aspartyl-L-phenylalanine methyl ester having low hygroscopicity
US4892820A (en) * 1987-06-10 1990-01-09 The Nutrasweet Company Solvent system for enzymatic coupling process
US4897507A (en) * 1987-07-22 1990-01-30 Ajinomoto Co., Inc. Method for producing α-L-aspartyl-L-phenylalanine derivatives
JP2508803B2 (en) * 1987-07-22 1996-06-19 味の素株式会社 Process for producing α-L-aspartyl-L-phenylalanine derivative
US5144073A (en) * 1988-08-31 1992-09-01 Hubbs John C Process for preparation of dipeptides
US4992552A (en) * 1988-08-31 1991-02-12 Eastman Kodak Company Process for preparation of amino acids
US5214145A (en) * 1988-08-31 1993-05-25 Eastman Kodak Company Trisubstituted piperazin-2,5-diones
ATE141613T1 (en) * 1990-03-15 1996-09-15 Nutrasweet Co PROCESS FOR PREPARING ASPARTAME FROM A DIKETOPIPERAZINE AND NEW INTERMEDIATE PRODUCTS AND DERIVATIVES THEREFOR
JPH05117246A (en) * 1991-10-23 1993-05-14 Ajinomoto Co Inc New 2,5-dioxopiperazine compound, its production and production of alpha-l-aspartyl-l-phenylalanine methyl ester derivative
JPH05194587A (en) * 1992-01-14 1993-08-03 Ajinomoto Co Inc Method for purifying alpha-l-aspartyl-l-phenylalanine methyl ester
JP3208874B2 (en) * 1992-12-07 2001-09-17 味の素株式会社 Method for producing α-L-aspartyl-L-phenylalanine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2261926C3 (en) * 1972-12-18 1978-11-30 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Process for the production of DL-methionyl-DL-methionine
JPS5113737A (en) * 1974-07-23 1976-02-03 Ajinomoto Kk Arufua ll asuparuchiru ll fueniruaraninteikyuarukiruesuteruno seizoho
US4173562A (en) * 1976-12-27 1979-11-06 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester
JPS58185545A (en) * 1982-04-22 1983-10-29 Ajinomoto Co Inc Preparation of alpha-l-aspartyl-l-phenylalanine methyl ester or its hydrochloride
JPS59219258A (en) * 1983-05-28 1984-12-10 Ajinomoto Co Inc Preparation of alpha-l-aspartyl-l-phenylalanine methyl ester or its hydrochloride
US4618695A (en) * 1983-06-02 1986-10-21 Ajinomoto Co., Inc. Method of preparing methyl ester and its hydrochloride
JPS59227849A (en) * 1983-06-08 1984-12-21 Ajinomoto Co Inc Crystallization and separation of l-alpha-aspartyl-l- phenylalaninemethyl ester

Also Published As

Publication number Publication date
JPH0564159B2 (en) 1993-09-14
US4634790A (en) 1987-01-06
IT1183336B (en) 1987-10-22
IT8519484A0 (en) 1985-02-13
NL193542C (en) 2000-01-04
FR2559773B1 (en) 1994-01-14
JPS60174799A (en) 1985-09-09
NL8500325A (en) 1985-09-16
FR2559773A1 (en) 1985-08-23

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V4 Discontinued because of reaching the maximum lifetime of a patent

Effective date: 20050206