NL190488B - Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2r-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat. - Google Patents

Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2r-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat.

Info

Publication number: NL190488B
Authority: NL; Netherlands
Prior art keywords: preparation; methyloxiranyl; phosphonate; hydroxymethyl; cis
Prior art date: 1978-07-19

Application number

NLAANVRAGE7905635,A

Other languages

English (en)

Other versions

NL7905635A (nl

NL190488C (nl

Original Assignee

Zambon Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-07-19

Filing date

1979-07-19

Publication date

1993-10-18

1979-07-19 Application filed by Zambon Spa filed Critical Zambon Spa

1980-01-22 Publication of NL7905635A publication Critical patent/NL7905635A/nl

1993-10-18 Publication of NL190488B publication Critical patent/NL190488B/nl

1994-03-16 Application granted granted Critical

1994-03-16 Publication of NL190488C publication Critical patent/NL190488C/nl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/62—Quaternary ammonium compounds
- C07C211/63—Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
- C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NLAANVRAGE7905635,A 1978-07-19 1979-07-19 Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2R-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat. NL190488C (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT25853/78A IT1112282B (it)	1978-07-19	1978-07-19	Bis-(2-ammonio-2-idrossimetil-1,3-propandiolo)(2r-cis)-(3-metilossiranil)fosfonato
IT2585378		1978-07-19

Publications (3)

Publication Number	Publication Date
NL7905635A NL7905635A (nl)	1980-01-22
NL190488B true NL190488B (nl)	1993-10-18
NL190488C NL190488C (nl)	1994-03-16

Family

ID=11217928

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NLAANVRAGE7905635,A NL190488C (nl)	1978-07-19	1979-07-19	Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2R-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat.

Country Status (21)

Country	Link
US (1)	US4727065A (nl)
JP (1)	JPS5517381A (nl)
AT (1)	AT371823B (nl)
AU (1)	AU526464B2 (nl)
BE (1)	BE877286A (nl)
CA (1)	CA1108631A (nl)
CH (1)	CH640823A5 (nl)
DE (1)	DE2926847A1 (nl)
DK (1)	DK148023C (nl)
ES (1)	ES482268A1 (nl)
FR (1)	FR2431506A1 (nl)
GB (1)	GB2025975B (nl)
GR (1)	GR75071B (nl)
IE (1)	IE48781B1 (nl)
IL (1)	IL57680A (nl)
IT (1)	IT1112282B (nl)
LU (1)	LU81500A1 (nl)
NL (1)	NL190488C (nl)
SE (1)	SE440360B (nl)
YU (1)	YU41411B (nl)
ZA (1)	ZA793354B (nl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1124610B (it) *	1979-10-18	1986-05-07	Zambo Spa	Mono(2-ammonio-2-idrossimetil-1,3-propandiolo) (2r-cis)-(o-metilossiranil)fosfonato
IT1136652B (it) *	1981-06-04	1986-09-03	Crinos Industria Farmaco	Compesizione farmaceutica di fosfomicina in compresse da succhiare
DE3203937C2 (de) *	1982-02-05	1985-10-03	Luc Dr. 4150 Krefeld Barrut	Verfahren und Vorrichtung zum maschinellen Sanieren oder Korrigieren mindestens eines Zahnes oder zum maschinellen Vorbereiten mindestens eines Zahnes für eine festsitzende prothetische Restaurierung und zum maschinellen Herstellen der festsitzenden prothetischen Restaurierung
CH660306A5 (de) *	1984-10-05	1987-04-15	Schering Spa	Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.
CH660305A5 (de) *	1984-10-05	1987-04-15	Schering Spa	Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.
US5191094A (en) *	1989-07-27	1993-03-02	Zambon Group S.P.A.	Mono (2-ammonium-2-hydroxymethyl-1,3-propanediol) (2R,cis)-1,2-epoxypropyl-phosphonate with improved characteristics of stability and processing
IT1231013B (it) *	1989-07-27	1991-11-08	Zambon Spa	Mono (2 ammonio 2 idrossimetil 1,3 propandiolo)(2r,cis) 1,2 epossipropil fosfonato avente migliorate caratteristiche di stabilita' e lavorabilita'.
ITMI20021725A1 (it) *	2002-08-01	2002-10-31	Zambon Spa	Composizioni farmaceutiche ad attivita' antibiotica.
EP1762573A1 (en)	2005-09-08	2007-03-14	Interquim, S.A. De C.V.	A process for the preparation of fosfomycin salts
ES2385158B1 (es) *	2010-12-24	2013-05-28	Arafarma Group, S.A.	Composición farmacéutica de fosfomicina
CN102807586B (zh)	2012-08-31	2015-05-13	东北制药集团股份有限公司	磷霉素氨盐的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3639590A (en) *	1967-07-25	1972-02-01	Merck & Co Inc	Antibacterial composition containing (-) (cis-1 2-epoxypropyl) phosphoric acid
US3641063A (en) *	1968-01-22	1972-02-08	Merck & Co Inc	Antibiotic purification process

1978
- 1978-07-19 IT IT25853/78A patent/IT1112282B/it active
1979
- 1979-06-25 GB GB7922098A patent/GB2025975B/en not_active Expired
- 1979-06-26 BE BE0/195974A patent/BE877286A/xx not_active IP Right Cessation
- 1979-06-27 CH CH601579A patent/CH640823A5/it not_active IP Right Cessation
- 1979-06-27 IL IL57680A patent/IL57680A/xx unknown
- 1979-06-29 AU AU48552/79A patent/AU526464B2/en not_active Expired
- 1979-07-02 GR GR59481A patent/GR75071B/el unknown
- 1979-07-03 DE DE19792926847 patent/DE2926847A1/de active Granted
- 1979-07-05 ZA ZA793354A patent/ZA793354B/xx unknown
- 1979-07-05 FR FR7917455A patent/FR2431506A1/fr active Granted
- 1979-07-05 YU YU1632/79A patent/YU41411B/xx unknown
- 1979-07-06 ES ES482268A patent/ES482268A1/es not_active Expired
- 1979-07-11 AT AT0484079A patent/AT371823B/de not_active IP Right Cessation
- 1979-07-13 LU LU81500A patent/LU81500A1/xx unknown
- 1979-07-18 DK DK302379A patent/DK148023C/da not_active IP Right Cessation
- 1979-07-18 JP JP9046879A patent/JPS5517381A/ja active Granted
- 1979-07-18 SE SE7906172A patent/SE440360B/sv unknown
- 1979-07-19 NL NLAANVRAGE7905635,A patent/NL190488C/nl not_active IP Right Cessation
- 1979-07-19 CA CA332,193A patent/CA1108631A/en not_active Expired
- 1979-08-08 IE IE1366/79A patent/IE48781B1/en not_active IP Right Cessation
1986
- 1986-01-23 US US06/824,922 patent/US4727065A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NL7905635A (nl)	1980-01-22
LU81500A1 (fr)	1979-10-31
JPS5517381A (en)	1980-02-06
US4727065A (en)	1988-02-23
AT371823B (de)	1983-08-10
SE7906172L (nl)	1980-01-20
IL57680A (en)	1986-01-31
SE440360B (sv)	1985-07-29
ZA793354B (en)	1980-07-30
IE48781B1 (en)	1985-05-15
GB2025975A (en)	1980-01-30
CA1108631A (en)	1981-09-08
JPS6248678B2 (nl)	1987-10-15
AU526464B2 (en)	1983-01-13
CH640823A5 (it)	1984-01-31
IT1112282B (it)	1986-01-13
ES482268A1 (es)	1980-04-16
BE877286A (fr)	1979-12-27
IT7825853A0 (it)	1978-07-19
IE791366L (en)	1980-01-19
GB2025975B (en)	1983-02-02
IL57680A0 (en)	1979-10-31
DE2926847A1 (de)	1980-02-07
YU163279A (en)	1983-02-28
NL190488C (nl)	1994-03-16
DK302379A (da)	1980-01-20
DE2926847C2 (nl)	1988-11-10
ATA484079A (de)	1982-12-15
DK148023C (da)	1985-07-08
GR75071B (nl)	1984-07-13
DK148023B (da)	1985-02-04
YU41411B (en)	1987-04-30
AU4855279A (en)	1980-01-24
FR2431506B1 (nl)	1984-11-23
FR2431506A1 (fr)	1980-02-15

Similar Documents

Publication	Publication Date	Title
NL7713152A (nl)	1978-06-27	Zwavel- en fosforbevattende organosiliciumver- bindingen, werkwijze voor de bereiding daarvan en toepassing daarvan.
IT8467264A1 (it)	1985-09-20	Procedimento di preparazione di vescichette lipidiche per evaporazione di solventi.
NO153854C (no)	1986-06-04	Fremgangsmaate for fremstilling av en vandig ionisk polyuretandispersjon.
NL7614584A (nl)	1977-07-07	Werkwijze voor de bereiding van n-fosfonomethyl- glycine.
NL7902850A (nl)	1979-10-29	Contactmassa voor heterogene katalyse.
NL189127C (nl)	1993-01-18	Werkwijze voor de bereiding van 1,1-diesters.
NL7903450A (nl)	1979-11-06	Polymere samenstellingen voor membranen.
NL7900695A (nl)	1979-07-31	Fosfor.
NO154165C (no)	1986-07-30	Fremgangsmaate ved fremstilling av 2,3,5-triklorpyridin.
NO793383L (no)	1980-04-25	Fordampningsapparat.
NL190488B (nl)	1993-10-18	Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2r-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat.
NL7903418A (nl)	1979-11-05	Synchroniseerinrichting voor versnellingsbak.
NL183357C (nl)	1988-10-03	(2.3-dihydro-2.2-dimethyl-benzofuran-7-yloxy-n-methylcarbamoyl)-(n'-alkylcarbamoyl)-sulfiden, werkwijze voor de bereiding daarvan, werkwijze voor de bereiding van een insecticide preparaat alsmede werkwijze voor de bestrijding van insecten.
DK157451C (da)	1990-05-21	Analogifremgangsmaade til fremstilling af 2,4-diamino-6-alkoxybenzyl-5-methylpyridooe2,3-daapyrimidiner eller farmaceutisk acceptable syreadditionssalte deraf
IT7926898A0 (it)	1979-10-30	Procedimento per preparare 1,2,3-tiadiazol-5-il-uree.
NL7901598A (nl)	1979-09-05	Machine voor de fabricage van pallets.
IT7926581A0 (it)	1979-10-18	(2r-cis)-(0-metilossiranil)fosfonatmono(2-ammonio-2-idrossimetil-1,3-p o. ropandiolo)
DK148281C (da)	1985-11-11	Analogifremgangsmaade til fremstilling af 8a-substituerede 8,8a-desoxy-8,8a-dihydrooleandomycin-forbindelser eller farmaceutiskacceptable syreadditionssalte deraf
NL7901215A (nl)	1979-08-20	Dieetisch voedingsmiddel, werkwijze voor de bereiding daarvan.
SE7908629L (sv)	1980-04-28	Ett nytt forfarande for framstellning av 6-piperidino-2,4-diaminopyrimidin-3-oxid
NL7902985A (nl)	1979-10-19	Werkwijze voor de bereiding van zouten van pyrodruiven- zuur.
NL190535C (nl)	1994-04-18	Preparaten, omvattende lactaatdehydrogenase alsmede werkwijze voor de bereiding daarvan.
NL7705444A (nl)	1977-11-24	Werkwijze voor de bereiding van perfluor-4-oxo- -2,5-dimethyl-2-fluorcarbonyl-1,3-dioxolan.
NO830046L (no)	1983-07-12	Fremgangsmaate for fremstilling av 6-aminoalkylpenicillansyre-1,1-dioksyder.
BE878034A (nl)	1980-02-04	Dieticum, werkwijze voor de bereiding daarvan, toepassing daarvan

Legal Events

Date	Code	Title	Description
1985-01-01	A85	Still pending on 85-01-01
1986-09-01	BA	A request for search or an international-type search has been filed
1986-09-01	BB	A search report has been drawn up
1986-11-03	BC	A request for examination has been filed
1996-01-02	SNR	Assignments of patents or rights arising from examined patent applications	Owner name: ZAMBON GROUP S.P.A.
1999-09-01	V4	Discontinued because of reaching the maximum lifetime of a patent	Free format text: 19990719