NL1026716A1 - Verbindingen. - Google Patents

Verbindingen.

Info

Publication number: NL1026716A1
Authority: NL; Netherlands
Prior art keywords: connections
Prior art date: 2003-07-25

Application number

NL1026716A

Other languages

English (en)

Other versions

NL1026716C2 (nl

Inventor

Christopher Gordon Barber

Mark Edward Bunnage

John Wilson Harvey

John Paul Mathias

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-07-25

Filing date

2004-07-23

Publication date

2005-01-26

2004-07-23 Application filed by Pfizer filed Critical Pfizer

2005-01-26 Publication of NL1026716A1 publication Critical patent/NL1026716A1/nl

2005-10-05 Application granted granted Critical

2005-10-05 Publication of NL1026716C2 publication Critical patent/NL1026716C2/nl

Classifications

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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
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- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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US (4)	US20090035313A1 (nl)
EP (2)	EP1651640B1 (nl)
JP (2)	JP4012935B2 (nl)
KR (2)	KR20060034300A (nl)
CN (2)	CN1860113A (nl)
AP (2)	AP2006003484A0 (nl)
AR (2)	AR045090A1 (nl)
AT (2)	ATE353893T1 (nl)
AU (2)	AU2004259133A1 (nl)
BR (2)	BRPI0412834A (nl)
CA (2)	CA2533624A1 (nl)
CR (1)	CR8205A (nl)
CY (1)	CY1106343T1 (nl)
DE (2)	DE602004006627T2 (nl)
DK (2)	DK1651640T3 (nl)
EA (2)	EA200600018A1 (nl)
EC (2)	ECSP066304A (nl)
ES (2)	ES2280980T3 (nl)
GB (1)	GB0317498D0 (nl)
GT (2)	GT200400143A (nl)
HR (2)	HRP20051021A2 (nl)
IL (2)	IL172793A0 (nl)
IS (2)	IS8201A (nl)
MA (2)	MA27930A1 (nl)
MX (2)	MXPA06000986A (nl)
NL (2)	NL1026717C2 (nl)
NO (2)	NO20060314L (nl)
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PA (2)	PA8607701A1 (nl)
PE (2)	PE20050329A1 (nl)
PL (2)	PL1651641T3 (nl)
PT (2)	PT1651640E (nl)
RS (1)	RS20060051A (nl)
SI (2)	SI1651641T1 (nl)
TN (2)	TNSN06026A1 (nl)
TW (2)	TW200524916A (nl)
UY (2)	UY28433A1 (nl)
WO (2)	WO2005009995A1 (nl)
ZA (2)	ZA200510421B (nl)

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PE20060272A1 (es)	2004-05-24	2006-05-22	Glaxo Group Ltd	(2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
WO2006077497A1 (en) *	2005-01-21	2006-07-27	Pfizer Limited	Crystalline forms cis-5-fluoro-n-[4-(2-hydroxy-4-methylbenzamido) cyclohexyl]-2-(tetrahydrothiopyran-a-yloxy) nicotinamide
EP1683795A1 (en) *	2005-01-21	2006-07-26	Pfizer Limited	Crystalline forms of cis-5-fluoro-N-¬4-(2-hydroxy-4-methylbenzamido)cyclohexyl\|-2-(tetrahydrothiopyran-4-yloxy)nicotinamide
SI2366393T1 (sl) *	2005-04-19	2013-12-31	Takeda Gmbh	Roflumilast za zdravljenje pljučne hipertenzije
GB0514809D0 (en)	2005-07-19	2005-08-24	Glaxo Group Ltd	Compounds
US7926591B2 (en) *	2006-02-10	2011-04-19	Halliburton Energy Services, Inc.	Aqueous-based emulsified consolidating agents suitable for use in drill-in applications
US20090305993A1 (en) *	2006-02-24	2009-12-10	Ironwood Pharmaceuticals, Inc.	Methods and composition for the treatment of gastrointestinal disorders
EP2857015B1 (en) *	2008-03-18	2021-05-05	Arena Pharmaceuticals, Inc.	Modulators of the prostacyclin (PG12) receptor useful for the treatment of disorders related thereto
CN103880757B (zh) *	2014-04-15	2016-02-24	上海毕得医药科技有限公司	一种5-羟基嘧啶-2-羧酸的合成方法
AU2018227842B2 (en)	2017-03-01	2024-05-02	Arena Pharmaceuticals, Inc.	Compositions comprising PGI2-receptor agonists and processes for the preparation thereof
CA3162047A1 (en) *	2019-12-23	2021-07-01	Anthony Pinkerton	Ectonucleotide pyrophosphatase/phosphodiesterase 1 (enpp1) modulators and uses thereof
US20230088684A1 (en) *	2020-01-31	2023-03-23	The Lubrizol Corporation	Processes for Producing Alkyl Salicylic Acids and Overbased Detergents Derived Therefrom
CN111302945B (zh) *	2020-02-21	2023-06-13	上海再启生物技术有限公司	3-羟基-4-甲氧基-2-硝基苯甲酸的制备方法
DE102020107795A1 (de)	2020-03-20	2021-09-23	Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein	Elektronen emittierende Keramik
IL314717A (en)	2022-02-15	2024-10-01	United Therapeutics Corp	Crystalline prostacyclin (IP) receptor agonist and uses thereof

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US20020111495A1 (en) *	1997-04-04	2002-08-15	Pfizer Inc.	Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes
IL132033A0 (en) *	1997-04-04	2001-03-19	Pfizer Prod Inc	Nicotinamide derivatives
DZ3406A1 (nl) *	2000-01-31	2001-08-09	Pfizer Prod Inc
AP2002002589A0 (en) *	2000-01-31	2002-09-30	Pfizer Prod Inc	Nicotinamide benzofused-heterocyclyl derivatives useful as selective inhibitors of PDE4 isozymes.
EA200300621A1 (ru) *	2001-01-31	2003-12-25	Пфайзер Продактс Инк.	Биарильные производные никотинамида, полезные в качестве ингибиторов изоферментов pde4
CN1489588A (zh) *	2001-01-31	2004-04-14	�Ʒ�	用作pde4同功酶抑制剂的噻唑基,噁唑基,吡咯基,和咪唑基羧酸酰胺衍生物

2003
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2004
- 2004-07-13 US US10/564,693 patent/US20090035313A1/en not_active Abandoned
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- 2004-07-13 AT AT04744026T patent/ATE353893T1/de not_active IP Right Cessation
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- 2004-07-13 EA EA200600100A patent/EA200600100A1/ru unknown
- 2004-07-13 PL PL04744038T patent/PL1651641T3/pl unknown
- 2004-07-13 EP EP04744038A patent/EP1651641B1/en not_active Expired - Lifetime
- 2004-07-13 OA OA1200600020A patent/OA13193A/en unknown
- 2004-07-13 PL PL04744026T patent/PL1651640T3/pl unknown
- 2004-07-13 US US10/564,694 patent/US20060178408A1/en not_active Abandoned
- 2004-07-13 DK DK04744038T patent/DK1651641T3/da active
- 2004-07-13 DE DE602004004794T patent/DE602004004794T2/de not_active Expired - Fee Related
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- 2004-07-13 ES ES04744038T patent/ES2286650T3/es not_active Expired - Lifetime
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- 2004-07-13 KR KR1020067001639A patent/KR20060039012A/ko not_active Application Discontinuation
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- 2004-07-20 US US10/896,085 patent/US20050020611A1/en not_active Abandoned
- 2004-07-20 US US10/896,068 patent/US20050043326A1/en not_active Abandoned
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2005
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2006
- 2006-01-05 IL IL173001A patent/IL173001A0/en unknown
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- 2006-01-20 NO NO20060314A patent/NO20060314L/no not_active Application Discontinuation
- 2006-01-23 EC EC2006006304A patent/ECSP066304A/es unknown
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2007
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Publication number	Publication date
AR045090A1 (es)	2005-10-12
NL1026716C2 (nl)	2005-10-05
EA200600018A1 (ru)	2006-08-25
PA8607701A1 (es)	2005-02-04
OA13194A (en)	2006-12-13
BRPI0412910A (pt)	2006-09-26
US20060178408A1 (en)	2006-08-10
TW200524916A (en)	2005-08-01
JP4016059B2 (ja)	2007-12-05
EA200600100A1 (ru)	2006-08-25
DK1651640T3 (da)	2007-05-14
US20050020611A1 (en)	2005-01-27
TNSN06026A1 (fr)	2007-10-03
PE20050329A1 (es)	2005-05-16
ECSP066304A (es)	2006-07-28
DE602004004794D1 (de)	2007-03-29
PA8607801A1 (es)	2005-02-04
PT1651641E (pt)	2007-07-13
ECSP066317A (es)	2006-07-28
AU2004259526A1 (en)	2005-02-03
UY28434A1 (es)	2005-02-28
MA27931A1 (fr)	2006-06-01
JP4012935B2 (ja)	2007-11-28
GB0317498D0 (en)	2003-08-27
ES2286650T3 (es)	2007-12-01
DE602004006627T2 (de)	2008-01-24
GT200400142A (es)	2005-03-03
HRP20051021A2 (en)	2006-05-31
JP2006528657A (ja)	2006-12-21
AR045091A1 (es)	2005-10-12
CA2533624A1 (en)	2005-02-03
UY28433A1 (es)	2005-02-28
ZA200600695B (en)	2007-05-30
NL1026717C2 (nl)	2005-11-01
IL173001A0 (en)	2006-06-11
PL1651641T3 (pl)	2007-09-28
EP1651641A1 (en)	2006-05-03
EP1651641B1 (en)	2007-05-23
TNSN06027A1 (fr)	2007-10-03
ATE353893T1 (de)	2007-03-15
WO2005009994A1 (en)	2005-02-03
BRPI0412834A (pt)	2006-09-26
IS8242A (is)	2006-01-19
PL1651640T3 (pl)	2007-06-29
AP2006003484A0 (en)	2006-02-28
ES2280980T3 (es)	2007-09-16
NO20060963L (no)	2006-02-27
CA2532249A1 (en)	2005-02-03
PE20050713A1 (es)	2005-09-14
CR8205A (es)	2006-07-14
US20050043326A1 (en)	2005-02-24
HRP20060017A2 (en)	2006-06-30
KR20060034300A (ko)	2006-04-21
AU2004259133A1 (en)	2005-02-03
IS8201A (is)	2005-12-27
OA13193A (en)	2006-12-13
EP1651640B1 (en)	2007-02-14
US20090035313A1 (en)	2009-02-05
WO2005009995A1 (en)	2005-02-03
GT200400143A (es)	2005-03-03
JP2006528625A (ja)	2006-12-21
NL1026717A1 (nl)	2005-01-26
SI1651640T1 (sl)	2007-06-30
SI1651641T1 (sl)	2007-10-31
AP2006003483A0 (en)	2006-02-28
MXPA06000936A (es)	2006-03-30
CN1829712A (zh)	2006-09-06
ZA200510421B (en)	2007-01-31
MA27930A1 (fr)	2006-06-01
MXPA06000986A (es)	2006-04-11
DE602004004794T2 (de)	2007-12-06
KR20060039012A (ko)	2006-05-04
DK1651641T3 (da)	2007-09-03
TW200521127A (en)	2005-07-01
CY1106343T1 (el)	2011-10-12
ATE362930T1 (de)	2007-06-15
RS20060051A (en)	2008-06-05
NO20060314L (no)	2006-04-06
EP1651640A1 (en)	2006-05-03
PT1651640E (pt)	2007-04-30
DE602004006627D1 (de)	2007-07-05
CN1860113A (zh)	2006-11-08
IL172793A0 (en)	2006-06-11

Publication	Publication Date	Title
NO20041144L (no)	2004-09-22	Gassloftingsventil.
NO20032883L (no)	2004-12-24	Bolgekraftverk.
NO20053993D0 (no)	2005-08-26	Kjemiske forbindelser.
NL1026717A1 (nl)	2005-01-26	Verbindingen.
FR2855029B1 (fr)	2006-04-07	Cache-pot.
NO20040394L (no)	2004-02-02	Fullpumpesentreringsstotte.
ITMI20031078A1 (it)	2004-11-30	Copridivano.
ITGE20030068A1 (it)	2005-03-06	Termoalgometro.
ES1055830Y (es)	2004-10-16	Mosquitera.
ES1055317Y (es)	2004-03-01	Escenario autotransportable.
ES1052590Y (es)	2003-05-01	Quiosco-consigna.
ES1055748Y (es)	2004-04-16	Portalamparas.
ES1054898Y (es)	2003-12-16	Video-postal.
ES1055888Y (es)	2004-05-16	Cuchara-pinza.
ES1054894Y (es)	2003-12-16	Caja-expositor.
ES1055854Y (es)	2004-05-16	Colchon-reposapies.
ES1054091Y (es)	2003-10-01	Muñeco-diana.
ES1053753Y (es)	2003-12-01	Caja-expositor.
ES1053821Y (es)	2003-09-01	Pasapures.
ES1055866Y (es)	2004-05-16	Mopa-fregona.
ES1056384Y (es)	2004-07-01	Capazo-cuna.
ES1056135Y (es)	2004-06-01	Lava-pies.
ES1056074Y (es)	2004-06-01	Portarretratos.
ES1055973Y (es)	2004-06-01	Mechero piezo-electrico.
ITRM20030094V0 (it)	2003-05-26	Salvachiave.

Legal Events

Date	Code	Title	Description
2005-04-01	AD1A	A request for search or an international type search has been filed
2005-08-01	RD2N	Patents in respect of which a decision has been taken or a report has been made (novelty report)	Effective date: 20050610
2005-12-01	PD2B	A search report has been drawn up
2009-04-01	VD1	Lapsed due to non-payment of the annual fee	Effective date: 20090201