NL1013258C2 - Combinations of active substances with insecticidal and acaricidal properties. - Google Patents

Description

Combinations of active substances with insecticidal and acaricidal properties

The present invention relates to new active compound combinations consisting of a known dihydrofuranone derivative on the one hand and other known pesticidal active substances on the other and which have very good insecticidal and acaricidal properties.

It is already known that the dihydrofuranone derivative of the formula O CH, II 1 10 o-c-c-c 2 h 5 O Cl 15 can be used for pest control, such as insects and undesired acaricides (see EP-A-0528156 ). The effectiveness of this medicine is good, but in some cases it leaves much to be desired at low amounts.

Furthermore, it is already known that numerous heterocyclic compounds, organotin compounds, benzoylureas and pyrethroids have insecticidal and acaricidal properties (see WO 93-22297, WO 93-10083, DE-A-2641343, EP-A-0347488, EP-A- 0210487, US-A-3264177 and EP-A-0234045). However, the effect of these substances is not always satisfactory at low applied amounts.

It has now been found that the new active compound combinations of the dihydrofuranone derivative of the formula 1 01 3258 2 O CH, OU-Crt - O Cl 10 and (1) the phenylhydrazine derivative of the formula 15 NH-NH-CO —CH (CH, L 0Ό

II

O

20 (Biphenazate) and / or (2) the macrolide with the common name

Abamectin (III) 25 and / or (3) the naphthalenedione derivative of the formula 1 013258 3 5 ^ 10-CO-CH, (ΟΙ /: ,,, (Acechinocyl) 10 and / or (4) the pyrrole derivative with the formula

Br CN

(V) CH-O-C 2 H 5 (Chlorphenapyr) 20 and / or (5) the thiourea derivative of the formula CH (CH 3) 2 <99 ° - <(9 / -NH "-if-NH-C ( CHA <V1> CH (CH3) 2 (Diafenthiuron) 30 and / or (6) the oxazoline derivative of the formula 1 013258/4 ^ vv / C (CH3) 3 \ = ζ V ° ° Λ F (VII) ( Etoxazole) 10 and / or (7) an organotin derivative of the formula 9 15 <^> - ίϊη- (VIII)

R

20 where N = 1 represents R -n

25 \ N

(Villa = azocyclotin), or R -OH 30 (Vlllb = cyhexatin), and / or (8) the pyrazole derivative of the formula 1 013258 5 H, C_ ΌΙ 5 ΝνΛ — νη-οη2- ^ Λ-0 « οη3,3 (, Χ) ch3 ο χ = / (Tebufenpyrad) 10 and / or (9) the pyrazole derivative of the formula 15 H3C _ CH = NO CHj- ^ COC (CH3) 3 ch3 20 (Fenpyroximate) and / or (10) the pyridazinone derivative of the formula 25 O Cl (CH3) 3C-N ^ j> - S-CH2 - {^ yC (CH3) 3 (XI) (Pyridaben) 30 and / or (11) the benzoylurea with the formula 1 013258 6 FF Cl \ <Qhco-nh — co-nh- ^ J ^ om0 ^ -cf3 (XII)

F

(Flufenoxuron) 10 and / or (12) the pyrethroid of the formula 15 H, C CH 3

V

A _> / ^ c-o-ch5 f 7 / ° -CH H 2 \ _ / (XIII) F.C ° / \ CH3 V ^ l

20 U ^ J

(Bifenthrine) and / or (13) the tetrazine derivative of the formula 25

Cl Cl fil yh IXIV> \ = / N ~ ~ N \ = / 30 (Clofentezine) and / or (14) the organotin derivative of the formula 1 013258 7 5 Ha? Ha Ί Γ? Ha y) —C — CH2 Sn — Ο — Sn CH2 — C— ^ ^ ch3 hh3 3 3 (XV) 10 (Fenbutatin oxide) and / or (15) the sulfenoic acid amide of the formula 15 f / / s ° 2 / ^ CH3 H> c-ijy -IVCH <xvi> - 'S-CCI2F CH3 (Tolylfluanide) and / or

(16) the pyrimidylphenol ethers of the formula (XVII) and (XVIII), known from WO

94/02470 and EP 0883991

25 F ^ ^ R

R = Cl (XVII); (4 - [(4-chloro-a, a, a-trifluoro-3-tolyl) oxy] -6 - [(a, α, α-4-tetrafluoro-3-tolyl) oxy] pyrimidine) R = NO2 (XVIII); 4 - [(4-chloro-a, a, a-trifluoro-3-tolyl) oxy] -6 - [(a, a, a-trifluoro-4-nitro-3-tolyl) oxy] pyrimidine R = Br ( XIX); 4 - [(4-chloro-a, a, a-trifluoro-3-tolyl) oxy] -6 - [(a, a, a-trifluoro-4- 1 01 3258 8 bromo-3-toyl) oxy] pyrimidine and / or (17) the macrolide with the formula CHa JL XHj ° cH2 y ° <s> = n 0y ^ F 9 yn t1 aJQv ^ och3 10 h ο ^^ γγΛ Γ ^ och3 Π502 V'I g \ «MlO 3 R & κ (XX) 15 (Spinosad) a mixture of preferably 85% Spinosyn AR = H 15% Spinosyn BR = CH3 have very good insecticidal and acaricidal properties.

Surprisingly, the insecticidal and acaricidal activity of the active compound combinations of the invention is significantly greater than the sum of the actions of the individual active compounds. So there is an unpredictable, real synergistic effect and not just a supplement of the effect.

The dihydrofuranone derivative of the formula (I) is known (see EP-A-0528156).

The formula (VIII) includes the organotin derivatives of the formulas 1 013258 9 9 s

1 Q

G ----- O

N

(\ 10 N- ^ (Villa) (Azocyclotin) and 15

Q

0—0 20 µl OH (Vlllb) (Cyhexatin).

In addition to the dihydrofuranone derivative of the formula (I), the insecticidal and acaricidal active ingredients present in the active compound combinations according to the invention are also known. In particular, the active substances are described in the following publications: (1) Phenylhydrazine derivative of the formula (II) WO 93-10083 (2) Macrolide with the common name abamectin (III) 30 DE-A-2717040 (3) Naphthalenedione derivative of the formula (IV) DE-A-2641343 (4) Pyrrole derivative of the formula (V) 1013258 10 EP-A-0347488 (5) Thiourea derivative of the formula (VI) EP-A-0210487 (6) Oxazoline derivative of the formula (VII) 5 WO 93-22297 (7) Organotin derivatives of the formulas (Villa)

The Pesticide Manual, ninth edition, page 48 and (VUIb) US-A-3264177 10 (8) Pyrazole derivative of the formula (IX)

Farm Chemicals Handbook 1998, C 328 (9) Pyrazole derivative of the formula (X) EP-A-0234045 (10) Pyridazinone derivative of the formula (XI) 15 EP-A-0134439 (11) Benzoylurea of the formula ( XII) EP-A-0161019 (12) Pyrethroid of the formula (XIII) EP-A-0049977 20 (13) Tetrazine derivative of the formula (XIV) EP-A-0005912 (14) Organotin derivative of the formula ( XV) DE-A-2115666 (15) Sulfenic acid amide of formula (XVI) 25 The Pesticide Manual, eleventh edition, 1997, page 1208 (16) Pyrimidylphenol ethers of formulas (XVII) to (XIX)

WO 94/02470 and EP-A-88399I

and (17) Spinosad of the formula (XX) EP-A-0375316

The active compound combinations according to the invention contain, in addition to the active compound of the formula (1), at least one active compound of the compounds 1013258 in groups (1) to (17). In addition, they can also contain further insecticidal and / or acaricidal active, mixed components.

When the active substances are present in certain weight ratios in the active compound combinations according to the invention, the synergistic effect is particularly evident. However, the weight ratios of the active compounds in the active compound combinations can be varied in a relatively wide range. In general, 1 part by weight of active compound of the formula (I) contains 0.1 to 5 parts by weight, preferably 0.2 to 3 parts by weight of group 10 active ingredient (1), 0.01 to 2 parts by weight, preferably 0 .05 to 1 part by weight of active substance from group (2), 0.1 to 5 parts by weight, preferably 0.2 to 3 parts by weight of active substance from group (3), 0.1 to 10 parts by weight, preferably 0.5 to 5 parts by weight of active substance from group (4), 1 to 10 parts by weight, preferably 2 to 5 parts by weight of active substance from group (5), 0.1 to 5 parts by weight, preferably 0.2 to 3 parts by weight of active substance from group (6 ), 0.5 to 10 parts by weight, preferably 1 to 5 parts by weight of active substance from group (7), 0.1 to 5 parts by weight, preferably 0.2 to 3 parts by weight of active substance from group (8), 0.1 up to 5 parts by weight, preferably 0.2 to 3 parts by weight of the active compound from group 25 (9), 0.1 to 5 parts by weight, preferably 0.2 to 3 parts by weight of the active ingredient from group (10), 0.05 to 5 parts by weight, preferably 0.1 to 3 parts by weight of active substance from group (11), 0.01 to 2 parts by weight, preferably 0.05 to 1 part by weight of active substance from group (12), 0.5 up to 10 parts by weight, preferably 2 to 5 parts by weight of active ingredient from group (13), 1 01 3258 12 0.5 to 10 parts by weight, preferably 1 to 5 parts by weight of active substance from group (14), 0.5 to 10 parts by weight, preferably 1 to 5 parts by weight of active substance from group (15), 5 0.05 to 5 parts by weight, preferably 0.2 to 3 parts by weight of active substance from group (16) and / or 0.05 to 5 parts by weight, preferably 0 , 2 to 3 parts by weight of active substance from group (17).

The active compound combinations according to the invention are suitable for controlling pests, preferably arthropods and nematodes, in particular insects and spiders, which are used in agriculture, forests, stock and material protection as well as in the hygiene sector appearance. They are active against normally sensitive and resistant species as well as against all or separate development stages. The pests mentioned above include: From the order of the Isopoda e.g. Oniscus asellus, Armadillidium vulgare, Porcellio scaber.

From the order of the Diplopoda e.g. Blaniulus guttulatus.

From the order of the Chilopoda, e.g. Geophilus carpophagus, Scutigera spec.

From the order of the Symphyla, e.g. Scutigerella immaculata.

From the order of the Thysanura, e.g. Lepisma saccharina.

From the order of the Collembola, e.g. Onychiurus armatus.

From the order of the Blattaria e.g. Blatta orientalis, Periplaneta americana, Leuco-phaea maderae, Blatella germanica.

From the order of the Orthoptera, e.g. Acheta domesticus, Gryllotalpa spp., Locusta 25 migratoria migratorioides, Melanoplus differentialialis, Schistocerca gregaria.

From the order of the Dermaptera, e.g. Forficula auricularia.

From the order of the Isoptera, e.g. Reticuliter knife spp.

From the order of the Anoplura e.g. Phylloxera vastatrix, Pemphigus spp., Pediculus humanus corporis, Haematopinus spp., Linognathus spp.

From the order of the Mallophaga e.g. Trichodectes spp., Damalinea spp.

From the order of the Thysanoptera, e.g. Frankliniella occidentalis, Hercinothrips femoralis, Thrips palmi, Thrips tabaci.

1013258 ƒ 13

From the order of the Heteroptera, e.g. Eurygaster spp., Dysdercus intermedius, Piesma quadrata, Cimex lectularius, Rhodnius prolixus, Triatoma spp.

From the order of the Homoptera, e.g. Aleurodes brassicae, Bemisia tabaci, Trialeu-rodes vaporariorum, Aphis gossypii, Brevicoryne brassicae, Cryptomyzus ribis, Aphis 5 fabae, Doralis pomi, Eriosoma lanigerum, Hyalopterus arundinis, Macrosiphum avenae, Myzus, spp., Phorodonpoasc. , Euscelis bilobatus, Nephotettix cincticeps, Lecanium comi, Saissetia oleae, Laodelphax stria tellus, Nilaparvata lugens, Aonidiella aurantii, Aspidiotus hederae, Pseudococcus spp., Psylla spp.

From the order of the Lepidoptera, e.g. Pectinophora gossypiella, Bupalus piniarius,

Cheimatobia brumata, Lithocollelis blancardella, Hyponomeuta padella, Plutella macu-lipennis, Malacosoma neustria, Euproctis chrysorrhoea, lymantria spp., Bucculatrix thurberiella, Phyllocnistis citrella, Agrotis spp., Euxoa spp. exigua, mamestra brassicae, Panolis flammea, Prodenia litu-15 ra, Spodoptera spp., Trichoplusia ni, Carpocapsa pomonella, Pieris spp., Chilo spp., Pyrausta nubilalis, Ephestia kuehniella, Galleria mellonella, Tineola bissellielella, Hofmannella Cacoecia podana, Capua reticulana, Cho-ristoneura fumiferana, Clysia ambiguella, Homona magnanima, Tortrix viridana.

From the order of the Coleoptera, e.g. Anobium punctatum, Rhizopertha dominica, 20 Acanthoscelides obtectus, Acanthoscelides obtectus, Hylotrupes bajulus, Agelastfca alni, Leptinotarsa decemlineata, Phaedon cochleariae, Diabrotica spp. ., Otiorrhynchus sulcatus, Cosmopolites sordidus, Ceuthor-rhynchus assimilis, Hypera postica, Dermestes spp., Trogoderma spp., Anthrenus spp., 25 Attagenus spp., Lyctus spp., Meligethes aeneus, Ptinus sppus, Niptus holole. psylloides, Tribolium spp., Tenebrio molitor, Agriotes spp., Cono derus spp., Melolontha melolontha, Amphimallon solsti tialis, Costelytra zealandica.

From the order of the Hymenoptera, e.g. Diprion spp., Hoplocampa spp., Lasius spp., Monomorium pharaonis, Vespa spp.

From the order of the Diptera, e.g. Aedes spp., Anopheles spp., Culex spp., Droso phila melanogasler, Museums spp., Fannia spp., Calliphora erythrocephala, Lucilia spp., Chrysomyia spp., Cuterebra spp., Gastrophilus spp., Hyppobosca spp., Liriomyza , Stomoxys spp., Oestrus spp., Hypoderma spp., Tabanus spp., Tannia spp., Bibio hortu- 1 013258 14 lanus, Oscinella frit, Phorbia spp., Pegomyia hyoscyami, Ceratitis capitata, Dacus oleae, Tipula paludosa.

From the order of the Siphonaptera, e.g. Xenopsylla cheopis, Ceratophyllus spp.

From the order of the Arachnida, e.g. Scorpio maurus, latrodectus mactans.

From the order of the Acarina e.g. Acarus siro, Argas spp., Omithodoros spp., Der manyssus gallinae, Eriophyes ribis, Phyllocoptruta oleivora, Boophilus spp., Rhipice-phalus spp., Amblyomma spp., Hyalomma spp., Ixodes spp., Psoroptes spp. tes spp., Sarcoptes spp., Tarsonemus spp., Bryobia praetiosa, Panonychus spp., Tetra-nychus spp.

The active compound combinations according to the invention can be used particularly successfully in controlling insects and acaricides harmful to plants, such as, for example, against Tetrannychus spp., Panonychu spp., Hemi-tarsonemus spp., Tarsonemus spp., Brevipalpus spp., Phylocoptruta spp., Aculus spp., Bryobia spp. and Eriophyes spp.

The good plant tolerance of the active compound combinations in the concentrations necessary to control insects and acaricides allows treatment of plant parts above ground, of plant and seed material and of the soil. The active compound combinations according to the invention can be used before application to the foliage or as a mordant. The active compound combinations according to the invention can be converted into the usual formulations, such as solutions, emulsions, suspensions, powders, foams, pastes, granulates, aerosols, very fine encapsulations in polymers and in seed coating materials, as well as ULV formulations.

These formulations are prepared in known manner, such as e.g. by mixing the active substances resp. of the active compound combinations with extenders, i.e. liquid solvents, pressurized, liquid milled gases and / or solid carrier materials, optionally using surfactants, i.e. emulsifiers and / or dispersants and / or foaming agents. In the case of the use of water as a stretching agent, e.g. organic solvents are also used as auxiliary solvents. Suitable liquid solvents are mainly: aromatics, such as xylene, toluene or alkylnaphthalenes, chlorinated aromatics or chlorinated aliphatic hydrocarbons, such as chlorobenzenes, chloroethene or dichloromethane, aliphatic hydrocarbons, such as cyclo-1 013258 hexane or paraffins, e.g. petroleum fractions, alcohols such as butanol or glycol and their ethers and esters, ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, highly polar solvents such as dimethyl formamide and dimethyl sulfoxide, as well as water. By liquefied gaseous extenders and carrier materials is meant those liquids which are gaseous at normal temperature and under normal pressure, such as e.g. aerosol propellants, such as butane, propane, nitrogen and carbon dioxide. Suitable carrier materials include: e.g. natural stone flours, such as kaolin, clays, talc, chalk, quartz, attapulgite, montmorillonite or diatomaceous earth, and synthetic stone flours, such as highly dispersed silicas, aluminum oxide and silicates. Suitable carrier materials for granulates are, for example, crushed and fractionated natural stones such as calcite, marble pumice, sepiolite, dolomite, as well as synthetic granules of inorganic and organic flours, as well as granules of organic material such as sawdust, coconut shells, corncobs and tobacco stalks. Suitable emulsifying agents and / or foam-producing agents are: e.g. nonionic and anionic emulsifiers, such as polyoxyethylene fatty acid esters, polyoxyethylene fatty alcohol ethers, e.g. alkylaryl polyglycol ethers, alkyl sulfonates, alkyl sulfates, aryl sulfonates as well as protein hydrolysates. Suitable dispersants are: e.g. lignin sulphite waste liquors and methyl cellulose.

In the formulations, adhesives such as carboxymethyl cellulose, natural and synthetic, powdery, granular or latex polymers, such as gum arabic, polyvinyl alcohol, polyvinyl acetate, as well as natural phospholipids, such as cephalin and lecithin, and synthetic phospholipids, can be used. Further additives can be inorganic and vegetable oils.

Dyes such as inorganic pigments, e.g. iron oxide, titanium oxide, ferrocyanic blue and organic dyes such as alizarin, azo and metal phthalocyanine dyes and trace nutrients such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc are used.

The formulations generally contain 0.1 to 95% by weight, preferably 0.5 to 90% by weight, of active slippers.

The active compound combinations according to the invention may be present in the formulations in admixture with other known active substances, such as fungicides, insecticides, acaricides and herbicides and pesticides, as well as mixed with fertilizers or plant growth regulators.

The active compound combinations can be used as such, in the form of their formulations or the use forms prepared therefrom, such as ready-to-use solutions, emulsifiable concentrates, emulsions, suspensions, wettable powders, soluble powders and granulates. The application takes place in the usual manner, e.g. by pouring, spraying, spraying, ironing, dry pickling, damp pickling, wet pickling, emulsion pickling or incrustation.

When using the active compound combinations according to the invention, the amounts applied can be varied within a fairly wide range depending on the manner of application. In the treatment of plant parts, the amounts of active compound combinations applied are generally between 0.1 and 10,000 g / ha, preferably between 10 and 1000 g / ha.

The good insecticidal and acaricidal action of the active compound combinations according to the invention is shown in the following examples. While the individual active ingredients exhibit disadvantages in their action, the combinations exhibit an action greater than the sum of the individual activities.

A synergistic effect is always present in insecticides and acaricides when the action of the active compound combinations is greater than the sum of the effects of the separately applied active agents.

The expected effect for a given combination of two active substances may, according to S.R. Colby, Weeds 1_5 (1967), 22-22, are calculated as follows:

If X means the efficacy when the active substance A is applied in an applied amount of mg / ha, Y means the efficacy when the active substance B is applied in an applied amount of ng / ha and E means the effectiveness when the application is made of active substances A and B in applied amounts of m_en ng / ha means, 30 is then

X. Y

E = X + Y --- 100 1 01 3258 17

The efficacy is determined in%. 0% is an efficacy equivalent to that of the control, while an efficacy of 100% means no deterioration is observed.

If the actual effect is greater than calculated, then the effect effect combination is above additive, i.e. there is a synergistic effect. In this case, the actual observed efficiency should be greater than the expected efficiency (E) value calculated from the above formula.

The invention is illustrated in the following examples.

Example I

Tetrannychus test (OP resistant / spray treatment)

Solvent: 3 parts by weight of dimethylformamide 15 Emulsifier: 1 part by weight of alkylaryl polyglycol ether

To prepare an effective active ingredient composition, mix 1 part by weight of active ingredient or combination of active ingredients with the amount of solvent shown and the amount of emulsifier shown, and the concentrate is diluted with water to the desired concentration.

Bean plants (Phaseolus vulgaris), which are strongly affected by all stages of the general spider mite (Tetranychus urticae), are sprayed with an active substance composition at the desired concentration.

After the desired time, the kill is determined in%. In addition, 100% means that all spider mites were killed; 0% means that no spider mites were killed.

Active substances, concentrations of the active substances and test results are shown in the following table.

1 01 325S

18

Table A

Mites harmful to plants 5 Tetranychus test (OP resistant / spray treatment)

Active substance Concentration active substance kill rate in% in% after 7d

Known: O CH,

II I

O — C — C — C, Hc I ch3 c, ° 00008 50 o Cl (I) o —CO — CH3 0.00008 o

CyQ, "" o (IV)

According to the invention: 0.00008 found. ber.

(I) + (IV) +} 90 50 (1: 1) 0.00008 found. = found operation ber. = effect calculated according to Colby's formula 1013258

Claims (5)

Insecticides and acaricides, characterized by a content of a combination of active substances consisting of the dihydrofuranone derivative of the formula 5 O ChL n U 1 Ah3 CK-f> ^ <fl> O Cl and 15 (1) the phenylhydrazine derivative of the formula V-OCH 3 20 NH-NH-CO-CH (CH 3) 2 (H) O (biphenazate) and / or 25 ( 2) the macrolide with the common name Abamectin (III) and / or 30 (3) the naphthalenedione derivative of the formula 1013258 co-ch3 071, (Acechinocyl) 10 and / or (4) the pyrrole derivative with the formula Br CN 15 Cl ^ N \ / u (V) Ih2 — O-C; HS (Chlorphenapyr) 20 and / or (5) the thiourea derivative of the formula CH (CH3) 2 _ / - ° - <\ Γ / ~ J-yy-NH-C (CH3) 3 (VI) X == (S CH (CH3) 2 (Diafenthiuron) 30 and / or (6) the oxazoline derivative of the formula 1 01 3258 f F f ^ YC ( CH 3) 3 φτΧ, F (VII) (Etoxazole) 10 and / or (7) an organotin derivative of the formula Q φφ-Sn- (VIII) R 20 where N— R —N represents 25 \ = N ( Villa = azocyclotin), or R -OH represents 30 (VUIb = cyhexatin), and / or (8) the pyrazole derivative of the formula 1013258 HP Cl, Ή ~ -ΝΗ — CH2 — f VC (CH3) 3 CH3 b (Tebufenpyrad) 10 and / or (9) the pyrazole derivative of the formula HjC CH = N-O-CO-C (CH 3> 3} / {0 '(X) ch 3 20 (Fenpyroximate) and / or (10) the pyridazinone derivative of the formula (CH 3,3C-1H-S_CHr ^ -C (CHJ, 3 (X1> (Pyridaben) 30 and / or (11) the benzoyl urea with the formula 1013258 5 F \ C '\ ^ ^ —CO NH CO NH ^ Ο (XII) V (Flufenoxuron) 10 and / or (12) the pyrethroid of the formula 15 H3C CH3 'V-ph ^^^ C-O-CH, -XC-CH || 2 W (XIII) ° * 10 (Bifenthrine) and / or (13) the tetrazine derivative of the formula 25 Cl Cl% -% ~ Λ (XIV) \ = / n-n \ = / 30 (Clofentezine) and / or (14) the organotin derivative of the formula 1013258 5 Ha? Ha Ί ίΗ3 —C — CH2 Sn-o — Sn CH2 — j— CH3 ch3 3 3 (XV) 10 (Fenbutatin oxide) and / or (15) the sulfenoic acid amide of the formula HiCjy, ^ s% (CHi (xv ,, S-CCI2F CH3 (Tolylfluanide) and / or 20 (16) the pyrimidylphenol ethers of the formula (XVII) and (XVIII), known from EP 0883991 F ^ -0M0 ^ _ XF, R = Cl (XVII); (4 - [(4-chloro-a, a, a-trifluoro-3-tolyl) oxy] -6 - [(a, α, α-4-tetrafluoro-3-tolyl) oxy] pyrimidine) R = NC > 2 (XVIII); 4 - [(4-chloro-a, a, a-trifluoro-3-tolyl) oxy] -6 - [(a, a, a-trifluoro-4-nitro-3-tolyl) oxy] pyrimidine R = Br ( XIX); 4 - [(4-chloro-a, a, a-trifluoro-3-tolyl) oxy] -6 - [(a, a, a-trifluoro-4-1,013258 bromo-3-tolyl) oxy] pyrimidine and / or (17) the macrolide of the formula CH 5 Λ / »1 -OCH 3 10 JL AV = VHi A2 ^ och3 HsC> ° Λΐ ^> “" θ ^ <α: Ηι (XX) R ^ 15 (Spinosad) a mixture of preferably 85% Spinosyn AR = H 15% SpinosynB R = CH3 as well as stretching agents and / or surfactants 20 Agent according to claim 1, characterized in that in the active compound combinations the weight ratio of active compound of the formula (I) to - active compound from group (1) is between 1: 0.1 and 1: 5, - active substance from group (2) is between 1: 0.01 and 1: 2, 25. active substance from group (3) is between 1: 0.1 and 1: 5, - active substance from group (4) is between 1: 0.1 and 1:10, - active ingredient from group (5) is between 1: 1 and 1:10, - active ingredient from group (6) is between 1: 0.1 and 1: 5, - active ingredient from group (7) is between 1: 0.5 and 1:10, 30. active ingredient from group (8) is between 1: 0.1 and 1: 5, - active ingredient from group (9) is between 1 : 0.1 and 1: 5, - active substance from group (10) is between 1: 0.1 and 1: 5, - active substance from group (11) is between 1: 0.05 and 1: 5, 1 013258 / - active substance from group (12) is between 1: 0.01 and 1: 2, - active substance from group (13) is between 1: 0.5 and 1:10, - active substance from group (14 ) is between 1: 0.5 and 1:10, - active ingredient group (15) is between 1: 0.5 and 1:10, 5. active substance from group (16) is between 1: 0.05 and 1: 5 and - active substance from group (17) is between 1: 0, 05 and 1: 5. Method for controlling insects and acaricides, characterized in that combinations of active substances according to claim 1 are applied to the vermin and / or the living space thereof. Use of active compound combinations according to claim 1 for controlling insects and acaricides. Process for the preparation of insecticidal and acaricidal agents, characterized in that active compound combinations according to claim 1 are mixed with extenders and / or surfactants. 1 01 3258