MY170840A - Aqueous composition containing 2-amino-3-(4-bromobenzoyl) phenylacetic acid - Google Patents
Aqueous composition containing 2-amino-3-(4-bromobenzoyl) phenylacetic acidInfo
- Publication number
- MY170840A MY170840A MYPI2014702590A MYPI2014702590A MY170840A MY 170840 A MY170840 A MY 170840A MY PI2014702590 A MYPI2014702590 A MY PI2014702590A MY PI2014702590 A MYPI2014702590 A MY PI2014702590A MY 170840 A MY170840 A MY 170840A
- Authority
- MY
- Malaysia
- Prior art keywords
- bromobenzoyl
- amino
- phenylacetic acid
- aqueous composition
- composition containing
- Prior art date
Links
- ZBPLOVFIXSTCRZ-UHFFFAOYSA-N bromfenac Chemical compound NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1 ZBPLOVFIXSTCRZ-UHFFFAOYSA-N 0.000 title abstract 3
- 229920001214 Polysorbate 60 Polymers 0.000 abstract 2
- 229960000686 benzalkonium chloride Drugs 0.000 abstract 2
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 2
- 229930195729 fatty acid Natural products 0.000 abstract 2
- 239000000194 fatty acid Substances 0.000 abstract 2
- -1 fatty acid ester Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention relates to an aqueous composition comprising 2-amino-3-(4-bromobenzoyl)phenylacetic acid or a salt thereof, and optionally benzalkonium chloride and/or a polyoxyethylene sorbitan fatty acid ester. By means of restricting the contents of benzalkonium chloride and the polyoxyethylene sorbitan fatty acid ester to within specific ranges, a composition can be obtained in which the stability of 2-amino-3-(4-bromobenzoyl)phenylacetic acid or a salt thereof is maintained and there are no changes in appearance.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012073181 | 2012-03-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
MY170840A true MY170840A (en) | 2019-09-10 |
Family
ID=49260248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MYPI2014702590A MY170840A (en) | 2012-03-28 | 2013-03-28 | Aqueous composition containing 2-amino-3-(4-bromobenzoyl) phenylacetic acid |
Country Status (9)
Country | Link |
---|---|
JP (1) | JP5922609B2 (en) |
KR (1) | KR20140139501A (en) |
CN (1) | CN104203224A (en) |
IN (1) | IN2014DN07767A (en) |
MY (1) | MY170840A (en) |
PH (1) | PH12014502171A1 (en) |
SG (1) | SG11201405837YA (en) |
TW (1) | TWI604858B (en) |
WO (1) | WO2013147000A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20180016469A (en) * | 2015-06-10 | 2018-02-14 | 산텐 세이야꾸 가부시키가이샤 | Eye drops, and eye drops preservative efficacy methods |
KR20200099547A (en) * | 2017-12-14 | 2020-08-24 | 산텐 세이야꾸 가부시키가이샤 | Eye drops containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid or salt thereof |
CN114224830A (en) * | 2021-12-24 | 2022-03-25 | 辰欣药业股份有限公司 | Single-dose bacteriostatic-free ophthalmic preparation and preparation method thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002308764A (en) * | 2001-02-09 | 2002-10-23 | Taisho Pharmaceut Co Ltd | Ophthalmic pharmaceutical composition |
WO2005046700A1 (en) * | 2003-11-14 | 2005-05-26 | Senju Pharmaceutical Co., Ltd. | Aqueous solution preparation containing aminoglycoside antibiotic and bromfenac |
CN1823754A (en) * | 2006-03-28 | 2006-08-30 | 卢秀莲 | Sodium bromophenolate eye drops and its preparation method |
CN101313899B (en) * | 2007-06-01 | 2012-02-29 | 北京德众万全药物技术开发有限公司 | Medicament composition for eyes containing sodium bromfenac |
RU2010138799A (en) * | 2008-02-21 | 2012-03-27 | Иста Фармасьютикалз (Us) | OPHTHALMIC NON-STEROID ANTI-INFLAMMATORY AGENTS AS ADJUVENTS |
CN101322683B (en) * | 2008-07-30 | 2013-01-16 | 浙江三叶药业有限公司 | Gel for eye containing bromfenac sodium hydrate and preparation thereof |
CA2824433C (en) * | 2011-01-18 | 2019-11-12 | Senju Pharmaceutical Co., Ltd. | Aqueous liquid bromfenac composition having preservative efficacy |
JP6012231B2 (en) * | 2011-04-08 | 2016-10-25 | ロート製薬株式会社 | Bromfenac-containing composition |
-
2013
- 2013-03-27 TW TW102110918A patent/TWI604858B/en not_active IP Right Cessation
- 2013-03-28 WO PCT/JP2013/059211 patent/WO2013147000A1/en active Application Filing
- 2013-03-28 IN IN7767DEN2014 patent/IN2014DN07767A/en unknown
- 2013-03-28 KR KR1020147025807A patent/KR20140139501A/en not_active Abandoned
- 2013-03-28 MY MYPI2014702590A patent/MY170840A/en unknown
- 2013-03-28 JP JP2013068407A patent/JP5922609B2/en not_active Expired - Fee Related
- 2013-03-28 SG SG11201405837YA patent/SG11201405837YA/en unknown
- 2013-03-28 CN CN201380014630.8A patent/CN104203224A/en active Pending
-
2014
- 2014-09-26 PH PH12014502171A patent/PH12014502171A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
TWI604858B (en) | 2017-11-11 |
JP5922609B2 (en) | 2016-05-24 |
CN104203224A (en) | 2014-12-10 |
IN2014DN07767A (en) | 2015-05-15 |
PH12014502171A1 (en) | 2014-12-10 |
JP2013227300A (en) | 2013-11-07 |
WO2013147000A1 (en) | 2013-10-03 |
TW201343197A (en) | 2013-11-01 |
KR20140139501A (en) | 2014-12-05 |
SG11201405837YA (en) | 2014-11-27 |
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