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MY117092A - Chemotherapeutic pyrrolocarbazole derivatives - Google Patents

Chemotherapeutic pyrrolocarbazole derivatives

Info

Publication number
MY117092A
MY117092A MYPI95002255A MYPI9502255A MY117092A MY 117092 A MY117092 A MY 117092A MY PI95002255 A MYPI95002255 A MY PI95002255A MY PI9502255 A MYPI9502255 A MY PI9502255A MY 117092 A MY117092 A MY 117092A
Authority
MY
Malaysia
Prior art keywords
chemotherapeutic
pyrrolocarbazole derivatives
pyrrolocarbazole
derivatives
formula
Prior art date
Application number
MYPI95002255A
Inventor
Chris Allen Broka
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MY117092A publication Critical patent/MY117092A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

COMPOUNDS REPRESENTED BY THE FORMULA I: (FORMULA 1)WHEREIN:R1 IS HYDROGEN OR LOWER ALKYL;R2 IS HETEROARYL; AND R3 AND R4 ARE INDEPENDENTLY HYDROGEN OR LOWER ALKYL; AND THE PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, ARE USEFUL AS CHEMOTHERAPEUTIC AGENTS.
MYPI95002255A 1994-08-04 1995-08-02 Chemotherapeutic pyrrolocarbazole derivatives MY117092A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28604394A 1994-08-04 1994-08-04

Publications (1)

Publication Number Publication Date
MY117092A true MY117092A (en) 2004-05-31

Family

ID=23096813

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI95002255A MY117092A (en) 1994-08-04 1995-08-02 Chemotherapeutic pyrrolocarbazole derivatives

Country Status (30)

Country Link
US (1) US5721267A (en)
EP (1) EP0695755B1 (en)
JP (1) JP2672290B2 (en)
KR (1) KR100326790B1 (en)
CN (1) CN1051551C (en)
AT (1) ATE172463T1 (en)
AU (1) AU692563B2 (en)
BR (1) BR9503536A (en)
CA (1) CA2155148A1 (en)
CO (1) CO4410329A1 (en)
CZ (1) CZ288583B6 (en)
DE (1) DE69505470T2 (en)
DK (1) DK0695755T3 (en)
ES (1) ES2123873T3 (en)
FI (1) FI111258B (en)
HK (1) HK1012341A1 (en)
HU (1) HU225567B1 (en)
IL (1) IL114785A (en)
MA (1) MA23639A1 (en)
MY (1) MY117092A (en)
NO (1) NO304833B1 (en)
NZ (1) NZ272687A (en)
PE (1) PE34996A1 (en)
PL (1) PL180801B1 (en)
RU (1) RU2162089C2 (en)
SA (1) SA95160203B1 (en)
TR (1) TR199500954A1 (en)
TW (1) TW403652B (en)
UY (1) UY24010A1 (en)
ZA (1) ZA956327B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283203B1 (en) * 1996-03-07 1998-04-16 Ausimont Spa FIRE EXTINGUISHING COMPOSITIONS
US6020298A (en) * 1997-03-05 2000-02-01 Ausimont S.P.A. Solvent cleaning agents including additives of the formula Rf -CFX-L containing perfluoroalkylenic units
DE19744257B4 (en) * 1997-10-07 2004-04-15 Zentaris Gmbh Beta-carbolines and their use for the treatment of malignant and other diseases based on pathological cell proliferation
US7122679B2 (en) * 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
AU2002354499A1 (en) * 2001-12-18 2003-06-30 Kyowa Hakko Kogyo Co., Ltd. Indole derivative
CA2483496A1 (en) * 2002-04-26 2003-11-06 Warner-Lambert Company Llc Inhibitors of checkpoint kinases (wee1 and chk1)
US7094798B1 (en) 2002-04-26 2006-08-22 Pfizer Inc Inhibitors of checkpoint kinases (Wee1 and Chk1)
JP2012051804A (en) * 2008-12-26 2012-03-15 Kyoto Univ Eg5 inhibitor
EP3613729A1 (en) * 2009-06-10 2020-02-26 Chugai Seiyaku Kabushiki Kaisha Tetracyclic compounds
MY160110A (en) 2010-08-20 2017-02-28 Chugai Pharmaceutical Co Ltd Composition comprising tetracyclic compound
LT2902029T (en) 2012-09-25 2018-10-25 Chugai Seiyaku Kabushiki Kaisha Ret inhibitor
KR101577098B1 (en) 2012-11-20 2015-12-14 주식회사 두산 Organic compound and organic electroluminescent device comprising the same
CA3140565C (en) 2014-04-25 2022-10-11 Chugai Seiyaku Kabushiki Kaisha Preparation containing tetracyclic compound at high dose
RU2016146119A (en) 2014-04-25 2018-05-29 Чугаи Сейяку Кабусики Кайся NEW CRYSTAL OF TETRACYCLIC COMPOUND
TWI718102B (en) 2014-08-08 2021-02-11 日商中外製藥股份有限公司 Amorphous body of tetracyclic compound
KR102584344B1 (en) 2015-01-16 2023-09-27 추가이 세이야쿠 가부시키가이샤 Combination drug
WO2020050241A1 (en) 2018-09-04 2020-03-12 中外製薬株式会社 Method of producing tetracyclic compound
KR102509614B1 (en) * 2022-08-09 2023-03-13 김학수 Method and apparatus of manufacturing nonwoven fabric panel

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611762D0 (en) * 1986-05-14 1986-06-25 Wellcome Found Polycyclic biocidal compounds
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
CZ280738B6 (en) * 1988-02-10 1996-04-17 F. Hoffmann - La Roche And Co., Aktiengesellschaft Substituted pyrroles, their use for preparing medicaments and medicaments based thereon
DE3833008A1 (en) * 1988-09-29 1990-04-05 Goedecke Ag PYRROLOCARBOZOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT
MC2096A1 (en) * 1989-02-23 1991-02-15 Hoffmann La Roche SUBSTITUTED PYRROLES
GB2239013B (en) * 1989-11-01 1993-06-02 Toyama Chemical Co Ltd Novel isoindole derivatives and salts thereof,processes for producing the same and antitumor agent comprising the same
DE4005969A1 (en) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh NEW TRISUBSTITUTED PYRROLE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE4217964A1 (en) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazole imides and their use
AU678435B2 (en) * 1993-05-10 1997-05-29 F. Hoffmann-La Roche Ag Substituted pyrroles
WO1994027982A1 (en) * 1993-05-28 1994-12-08 Cephalon, Inc. Use of indolocarbazole derivatives to treat a pathological condition of the prostate

Also Published As

Publication number Publication date
SA95160203B1 (en) 2005-07-31
DK0695755T3 (en) 1999-06-28
CO4410329A1 (en) 1997-01-09
KR100326790B1 (en) 2002-07-27
ATE172463T1 (en) 1998-11-15
MA23639A1 (en) 1996-04-01
KR960007592A (en) 1996-03-22
IL114785A0 (en) 1995-11-27
CZ288583B6 (en) 2001-07-11
ZA956327B (en) 1996-02-04
ES2123873T3 (en) 1999-01-16
CN1123280A (en) 1996-05-29
JP2672290B2 (en) 1997-11-05
HU225567B1 (en) 2007-03-28
FI953710L (en) 1996-02-05
BR9503536A (en) 1996-06-04
TR199500954A1 (en) 1996-10-21
PL309874A1 (en) 1996-02-05
CN1051551C (en) 2000-04-19
NO953052L (en) 1996-02-05
FI111258B (en) 2003-06-30
NO304833B1 (en) 1999-02-22
NZ272687A (en) 1997-04-24
EP0695755B1 (en) 1998-10-21
EP0695755A1 (en) 1996-02-07
TW403652B (en) 2000-09-01
NO953052D0 (en) 1995-08-03
UY24010A1 (en) 2000-12-29
RU2162089C2 (en) 2001-01-20
DE69505470D1 (en) 1998-11-26
IL114785A (en) 1998-06-15
JPH0859666A (en) 1996-03-05
FI953710A0 (en) 1995-08-03
AU692563B2 (en) 1998-06-11
CA2155148A1 (en) 1996-02-05
PL180801B1 (en) 2001-04-30
HUT73437A (en) 1996-07-29
HK1012341A1 (en) 1999-07-30
AU2722095A (en) 1996-02-15
CZ199795A3 (en) 1996-02-14
HU9502270D0 (en) 1995-09-28
DE69505470T2 (en) 1999-05-12
US5721267A (en) 1998-02-24
PE34996A1 (en) 1996-10-01

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