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MY104920A - Peptide boronic acid inhibitors of trypsin-like proteases. - Google Patents

Peptide boronic acid inhibitors of trypsin-like proteases.

Info

Publication number
MY104920A
MY104920A MYPI88000593A MYPI19880593A MY104920A MY 104920 A MY104920 A MY 104920A MY PI88000593 A MYPI88000593 A MY PI88000593A MY PI19880593 A MYPI19880593 A MY PI19880593A MY 104920 A MY104920 A MY 104920A
Authority
MY
Malaysia
Prior art keywords
trypsin
boronic acid
proteases
acid inhibitors
peptide boronic
Prior art date
Application number
MYPI88000593A
Inventor
Bhikkappa Shenve Ashokkumar
Adrian Kettner Charles
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/178,368 external-priority patent/US5187157A/en
Application filed by Du Pont filed Critical Du Pont
Publication of MY104920A publication Critical patent/MY104920A/en

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PEPTIDES COMPRISING C-TERMINAL BORONIC ACID DERIVATIVES OF LYSINE, ORNITHINE, AND ARGININE, HOMOARGININE AND CORRESPONDING ISOTHIOURONIUM ANALOGS THEREOF, ARE REVERSIBLE INHIBITORS OF TRYPSIN-LIKE SERINE PROTEASES SUCH AS THROMBIN, PLASMA KALLIKREIN AND PLASMIN.
MYPI88000593A 1987-06-05 1988-06-04 Peptide boronic acid inhibitors of trypsin-like proteases. MY104920A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5957087A 1987-06-05 1987-06-05
US07/178,368 US5187157A (en) 1987-06-05 1988-04-06 Peptide boronic acid inhibitors of trypsin-like proteases

Publications (1)

Publication Number Publication Date
MY104920A true MY104920A (en) 1994-07-30

Family

ID=79961358

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI88000593A MY104920A (en) 1987-06-05 1988-06-04 Peptide boronic acid inhibitors of trypsin-like proteases.

Country Status (1)

Country Link
MY (1) MY104920A (en)

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