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Application filed by Biogen IncfiledCriticalBiogen Inc
Publication of MY102686ApublicationCriticalpatent/MY102686A/en
Preparation Of Compounds By Using Micro-Organisms
(AREA)
Abstract
RECOMBINANT DNA MOLECULES AND HOSTS TRANSFORMED WITH THEM WHICH PRODUCE POLYPEPTIDES DISPLAYING HBV ANTIGENICITY AND GENES CODING THEREOF AND METHODS OF MAKING AND USING THESE MOLECULES, HOSTS, GENES AND POLYPEPTIDES. THE RECOMBINANT DNA MOLECULES OF THIS INVENTION ARE CHARACTERISED BY STRUCTURAL GENES THAT CODE FOR AT LEAST ONE POLYPEPTIDE DISPLAYING HBV ANTIGENICITY. IN APPOPRIATE HOSTS THESE RECOMBINANT DNA MOLECULES PERMIT THE PRODUCTION AND IDENTIFICATION OF GENES AND POLYPEPTIDES CHARACTERISTIC OF HBV ANTIGENICITY AND THEIR USE IN COMPOSITIONS AND METHODS FOR DETECTING HBV VIRUS INFECTIONS IN HUMANS AND STIMULATING THE PRODUCTION OF ANTIBODIES AGAINST THIS INFLECTION.@@@(FIG. 12)
MYPI87001323A1978-12-221987-08-13Recombinant dna molecules and their method of production.
MY102686A
(en)
Bacillus cloning vectors, recombinant DNA molecules, bacillus hosts transformed with them and methods for expressing foreign DNA sequences and producing polypeptides coded thereby.
PROTEIN, DNA SEQUENCE, REPLICABLE EXPRESSION VEHICLE, MICROORGANISM OR CELL CULTURE, PLASMIDE, COMPOSITION, CELL CULTURE, USE OF SUCH PROTEIN, EXPRESSION PROCESS, PROCESS FOR THE PRODUCTION OF AN EXPRESSION VEHICLE AND PROCESSING VEHICLE PROCESS
GENE FRAGMENTS ENCODING THE VARIABLE REGION OF AN ANTI-HIV ANTIBODY, CHIMERA ANTI-HIV ANTIBODIES EXPRESSED BY THESE, AND METHOD FOR THE PRODUCTION THEREOF.