MXPA06001974A - Nuevos oxidos de sulfenamida. - Google Patents
Nuevos oxidos de sulfenamida.Info
- Publication number
- MXPA06001974A MXPA06001974A MXPA06001974A MXPA06001974A MXPA06001974A MX PA06001974 A MXPA06001974 A MX PA06001974A MX PA06001974 A MXPA06001974 A MX PA06001974A MX PA06001974 A MXPA06001974 A MX PA06001974A MX PA06001974 A MXPA06001974 A MX PA06001974A
- Authority
- MX
- Mexico
- Prior art keywords
- sulfenamide
- disclosed
- compounds
- oxides
- general formula
- Prior art date
Links
- QAZLUNIWYYOJPC-UHFFFAOYSA-M sulfenamide Chemical compound [Cl-].COC1=C(C)C=[N+]2C3=NC4=CC=C(OC)C=C4N3SCC2=C1C QAZLUNIWYYOJPC-UHFFFAOYSA-M 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
La presente invencion se refiere a compuestos de oxido de sulfenamida de formula general (I), en donde A, R1, R2, X1, X1??, X2, X2??, X3, X3??, X4, X4??, X5, X5??, definen una variedad de variables y en donde q es 0 o 1 y p es 1 o 2. Los compuestos descritos en los ejemplos son compuestos de oxido de sulfenamida de galactofuranosilo y glucofuranosilo, en donde la variable A es oxigeno. Tambien se describen metodos de sintesis de compuestos de formula general (I), composiciones farmaceuticas que los contienen y metodos para usarlos para tratar pacientes que sufren de una infeccion microbiana.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2003904501A AU2003904501A0 (en) | 2003-08-21 | Novel compounds III | |
| AU2003904500A AU2003904500A0 (en) | 2003-08-21 | Novel compounds II | |
| PCT/AU2004/001110 WO2005019236A1 (en) | 2003-08-21 | 2004-08-20 | Novel sulfenamide oxides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA06001974A true MXPA06001974A (es) | 2006-05-31 |
Family
ID=34218927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA06001974A MXPA06001974A (es) | 2003-08-21 | 2004-08-20 | Nuevos oxidos de sulfenamida. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1664071A1 (es) |
| JP (1) | JP2007502778A (es) |
| BR (1) | BRPI0413682A (es) |
| CA (1) | CA2535800A1 (es) |
| MX (1) | MXPA06001974A (es) |
| RU (1) | RU2006108577A (es) |
| WO (1) | WO2005019236A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7601716B2 (en) | 2006-05-01 | 2009-10-13 | Cephalon, Inc. | Pyridopyrazines and derivatives thereof as ALK and c-Met inhibitors |
| US9394333B2 (en) | 2008-12-02 | 2016-07-19 | Wave Life Sciences Japan | Method for the synthesis of phosphorus atom modified nucleic acids |
| BR112012000828A8 (pt) | 2009-07-06 | 2017-10-10 | Ontorii Inc | Novas pró-drogas de ácido nucleico e métodos de uso das mesmas |
| JP5868324B2 (ja) | 2010-09-24 | 2016-02-24 | 株式会社Wave Life Sciences Japan | 不斉補助基 |
| CA2842358C (en) | 2011-07-19 | 2020-07-14 | Wave Life Sciences Pte. Ltd. | Methods for the synthesis of functionalized nucleic acids |
| ES2862073T3 (es) | 2012-07-13 | 2021-10-06 | Wave Life Sciences Ltd | Grupo auxiliar asimétrico |
| SG10201912897UA (en) | 2014-01-16 | 2020-02-27 | Wave Life Sciences Ltd | Chiral design |
| EP3500581A4 (en) | 2016-08-17 | 2021-10-06 | Solstice Biologics, Ltd. | POLYNUCLEOTID CONSTRUCTIONS |
| WO2019006455A1 (en) | 2017-06-30 | 2019-01-03 | Solstice Biologics, Ltd. | AUXILIARIES OF CHIRAL PHOSPHORAMIDITIS AND METHODS OF USE THEREOF |
| RS66307B1 (sr) | 2019-12-06 | 2025-01-31 | Vertex Pharma | Supstituisani tetrahidrofurani kao modulatori natrijumskih kanala |
| KR20230017796A (ko) | 2020-05-27 | 2023-02-06 | 엑시얼 테라퓨틱스, 인크. | Tlr2 조절제 화합물, 약제학적 조성물 및 이들의 용도 |
| AR126073A1 (es) | 2021-06-04 | 2023-09-06 | Vertex Pharma | N-(hidroxialquil(hetero)aril)tetrahidrofuran carboxamidas como moduladores de canales de sodio |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050124559A1 (en) * | 2002-02-22 | 2005-06-09 | Von Itzstein Laurence M. | Antimicrobial agent |
-
2004
- 2004-08-20 WO PCT/AU2004/001110 patent/WO2005019236A1/en not_active Application Discontinuation
- 2004-08-20 RU RU2006108577/04A patent/RU2006108577A/ru not_active Application Discontinuation
- 2004-08-20 CA CA002535800A patent/CA2535800A1/en not_active Abandoned
- 2004-08-20 JP JP2006523486A patent/JP2007502778A/ja active Pending
- 2004-08-20 BR BRPI0413682-9A patent/BRPI0413682A/pt not_active Application Discontinuation
- 2004-08-20 EP EP04761147A patent/EP1664071A1/en not_active Withdrawn
- 2004-08-20 MX MXPA06001974A patent/MXPA06001974A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2535800A1 (en) | 2005-03-03 |
| JP2007502778A (ja) | 2007-02-15 |
| WO2005019236A1 (en) | 2005-03-03 |
| EP1664071A1 (en) | 2006-06-07 |
| BRPI0413682A (pt) | 2006-10-24 |
| RU2006108577A (ru) | 2007-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |