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MXPA05012249A - Derivados de arilcarbaldehido oxima y su uso como agentes estrogenicos. - Google Patents

Derivados de arilcarbaldehido oxima y su uso como agentes estrogenicos.

Info

Publication number
MXPA05012249A
MXPA05012249A MXPA05012249A MXPA05012249A MXPA05012249A MX PA05012249 A MXPA05012249 A MX PA05012249A MX PA05012249 A MXPA05012249 A MX PA05012249A MX PA05012249 A MXPA05012249 A MX PA05012249A MX PA05012249 A MXPA05012249 A MX PA05012249A
Authority
MX
Mexico
Prior art keywords
aryl
oxime derivatives
carbaldehyde oxime
estrogenic agents
estrogenic
Prior art date
Application number
MXPA05012249A
Other languages
English (en)
Inventor
Stephen Todd Cohn
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of MXPA05012249A publication Critical patent/MXPA05012249A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/48—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)

Abstract

Esta invencion proporciona moduladores de receptor de estrogeno que tiene la estructura (I) en donde R1-R5 son como se definen en la especificacion: o una sal farmaceuticamente aceptable del mismo.
MXPA05012249A 2003-05-16 2004-05-13 Derivados de arilcarbaldehido oxima y su uso como agentes estrogenicos. MXPA05012249A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47123803P 2003-05-16 2003-05-16
PCT/US2004/015195 WO2004103941A2 (en) 2003-05-16 2004-05-13 Aryl-carbaldehyde oxime derivatives and their use as estrogenic agents

Publications (1)

Publication Number Publication Date
MXPA05012249A true MXPA05012249A (es) 2006-02-10

Family

ID=33476817

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05012249A MXPA05012249A (es) 2003-05-16 2004-05-13 Derivados de arilcarbaldehido oxima y su uso como agentes estrogenicos.

Country Status (14)

Country Link
US (2) US7157491B2 (es)
EP (1) EP1633699B1 (es)
JP (1) JP2007503466A (es)
CN (1) CN100344610C (es)
AT (1) ATE350366T1 (es)
AU (1) AU2004241246A1 (es)
BR (1) BRPI0410645A (es)
CA (1) CA2525310A1 (es)
DE (1) DE602004004124T2 (es)
DK (1) DK1633699T3 (es)
ES (1) ES2277273T3 (es)
MX (1) MXPA05012249A (es)
PL (1) PL1633699T3 (es)
WO (1) WO2004103941A2 (es)

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DE602004004124D1 (de) 2007-02-15
DE602004004124T2 (de) 2007-04-26
WO2004103941A2 (en) 2004-12-02
AU2004241246A1 (en) 2004-12-02
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US7157491B2 (en) 2007-01-02
US20050009907A1 (en) 2005-01-13
ATE350366T1 (de) 2007-01-15
WO2004103941A3 (en) 2005-01-20
CN1791570A (zh) 2006-06-21
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