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MXPA05011064A - Combinaciones de paroxetina y [1-(r)-(3, 5-bis-trifluorometi l-fenil)-etil] -metilamida del acido 4-(s)- (4-acetil-piperazin -1-il)-2- (r)-(4-fluoro -2-metil- fenil)-piperidin -1-carboxilico para tratamiento de depresion y/o ansiedad. - Google Patents

Combinaciones de paroxetina y [1-(r)-(3, 5-bis-trifluorometi l-fenil)-etil] -metilamida del acido 4-(s)- (4-acetil-piperazin -1-il)-2- (r)-(4-fluoro -2-metil- fenil)-piperidin -1-carboxilico para tratamiento de depresion y/o ansiedad.

Info

Publication number
MXPA05011064A
MXPA05011064A MXPA05011064A MXPA05011064A MXPA05011064A MX PA05011064 A MXPA05011064 A MX PA05011064A MX PA05011064 A MXPA05011064 A MX PA05011064A MX PA05011064 A MXPA05011064 A MX PA05011064A MX PA05011064 A MXPA05011064 A MX PA05011064A
Authority
MX
Mexico
Prior art keywords
phenyl
combinations
methylamide
paroxetine
piperazin
Prior art date
Application number
MXPA05011064A
Other languages
English (en)
Inventor
Renzo Carletti
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of MXPA05011064A publication Critical patent/MXPA05011064A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invencion se refiere a combinaciones terapeuticas que comprenden paroxetina o sus sales o solvatos fisiologicamente aceptables y [1-(R) -(3, 5-bis-trifluorometil- fenil)-etil] -metilamida del acido 4-(S)- (4-acetil- piperazin-1-il) -2-(R)-(4- fluoro-2-metil -fenil)-piperidin -1-carboxilico o sus sales o solvatos farmaceuticamente aceptables, a composiciones farmaceuticas que contiene dichas combinaciones y a su uso en el tratamiento de depresion y/o ansiedad.
MXPA05011064A 2003-04-17 2004-04-16 Combinaciones de paroxetina y [1-(r)-(3, 5-bis-trifluorometi l-fenil)-etil] -metilamida del acido 4-(s)- (4-acetil-piperazin -1-il)-2- (r)-(4-fluoro -2-metil- fenil)-piperidin -1-carboxilico para tratamiento de depresion y/o ansiedad. MXPA05011064A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0308968.7A GB0308968D0 (en) 2003-04-17 2003-04-17 Medicaments
PCT/EP2004/004122 WO2004091616A1 (en) 2003-04-17 2004-04-16 Combinations of paroxetine and 4- (s) - (4-acetyl-piperazin-1-yl) -2- (r)- (4-fluoro-2-methyl-phenyl -piperidine-1-carboxylic acid [1- (r) -(3,5-bis-trifluoromethyl-phenyl) -ethyl] methylamide for treatment of depression and / or anxiety

Publications (1)

Publication Number Publication Date
MXPA05011064A true MXPA05011064A (es) 2006-04-18

Family

ID=9956996

Family Applications (2)

Application Number Title Priority Date Filing Date
MXPA05011063A MXPA05011063A (es) 2003-04-17 2004-04-16 Combinaciones que comprenden paroxetina y [1-(r)-(3,5-bis-trifluoro-2-metil-fenil)-etil]-metil amida del acido 2-(s)-(4-fluoro-2-metil-fenil)-piperazin-1-carboxilico para tratamiento de depresion y/o ansiedad.
MXPA05011064A MXPA05011064A (es) 2003-04-17 2004-04-16 Combinaciones de paroxetina y [1-(r)-(3, 5-bis-trifluorometi l-fenil)-etil] -metilamida del acido 4-(s)- (4-acetil-piperazin -1-il)-2- (r)-(4-fluoro -2-metil- fenil)-piperidin -1-carboxilico para tratamiento de depresion y/o ansiedad.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MXPA05011063A MXPA05011063A (es) 2003-04-17 2004-04-16 Combinaciones que comprenden paroxetina y [1-(r)-(3,5-bis-trifluoro-2-metil-fenil)-etil]-metil amida del acido 2-(s)-(4-fluoro-2-metil-fenil)-piperazin-1-carboxilico para tratamiento de depresion y/o ansiedad.

Country Status (18)

Country Link
US (4) US20060217395A1 (es)
EP (4) EP1615641A1 (es)
JP (4) JP2006523650A (es)
KR (2) KR20060003875A (es)
CN (2) CN1809355A (es)
AU (2) AU2004229179A1 (es)
BR (2) BRPI0409379A (es)
CA (2) CA2522313A1 (es)
CO (1) CO5700753A2 (es)
GB (1) GB0308968D0 (es)
IS (2) IS8129A (es)
MA (2) MA27730A1 (es)
MX (2) MXPA05011063A (es)
NO (2) NO20055368L (es)
PL (2) PL377857A1 (es)
RU (2) RU2005135647A (es)
WO (4) WO2004091616A1 (es)
ZA (2) ZA200508067B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203020D0 (en) * 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
GB0403149D0 (en) * 2004-02-12 2004-03-17 Glaxo Group Ltd Medicament
GB0409098D0 (en) * 2004-04-23 2004-05-26 Glaxo Group Ltd Medicament
GB0426942D0 (en) * 2004-12-08 2005-01-12 Glaxo Group Ltd Medicament
WO2007012968A2 (en) * 2005-07-29 2007-02-01 Aurobindo Pharma Ltd Stable dosage form of an antidepressant
GB0621229D0 (en) * 2006-10-20 2006-12-06 Glaxo Group Ltd Novel use
US20100105688A1 (en) 2007-01-24 2010-04-29 Glaxo Group Limited Pharmaceutical compositions comprising 3,5-diamino-6-(2,3-dichlophenyl)-1,2,4-triazine or r(-)-2,4-diamino-5-(2,3-dichlorophenyl)-6-fluoromethyl pyrimidine and an nk1
WO2012175434A1 (en) * 2011-06-20 2012-12-27 Glaxo Group Limited Pharmaceutical formulations comprising vestipitant
CN103446066B (zh) * 2013-09-16 2014-12-24 南通丝乡丝绸有限公司 帕罗西汀冻干粉针及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IS4208A (is) * 1993-09-22 1995-03-23 Glaxo Group Limited 3-(tetrazólýl-benzyl)amínó-piperadidín afleiður
US6117855A (en) * 1996-10-07 2000-09-12 Merck Sharp & Dohme Ltd. Use of a NK-1 receptor antagonist and an antidepressant and/or an anti-anxiety agent
WO1998047514A1 (en) * 1997-04-24 1998-10-29 Merck Sharp & Dohme Limited Use of an nk-1 receptor antagonist and an ssri for treating obesity
GB9923748D0 (en) * 1999-10-07 1999-12-08 Glaxo Group Ltd Chemical compounds
US6436928B1 (en) * 1999-12-17 2002-08-20 Schering Corporation Selective neurokinin antagonists
KR20020067548A (ko) * 1999-12-17 2002-08-22 쉐링 코포레이션 선택적인 뉴로키닌 길항제
GT200100147A (es) * 2000-07-31 2002-06-25 Derivados de imidazol
GB0025354D0 (en) * 2000-10-17 2000-11-29 Glaxo Group Ltd Chemical compounds
GB0119797D0 (en) * 2001-08-14 2001-10-03 Glaxo Group Ltd Chemical compounds
ATE374183T1 (de) * 2001-11-13 2007-10-15 Schering Corp Nk1-antagonisten
GB0203020D0 (en) * 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
US20060241143A1 (en) 2006-10-26
CA2522311A1 (en) 2004-10-28
AU2004229181A1 (en) 2004-10-28
EP1613325A1 (en) 2006-01-11
JP2006523652A (ja) 2006-10-19
CN1809359A (zh) 2006-07-26
PL377857A1 (pl) 2006-02-20
BRPI0409377A (pt) 2006-04-25
BRPI0409379A (pt) 2006-04-25
EP1615641A1 (en) 2006-01-18
ZA200508068B (en) 2007-02-28
WO2004091615A1 (en) 2004-10-28
CA2522313A1 (en) 2004-10-28
WO2004091624A1 (en) 2004-10-28
RU2005135649A (ru) 2006-03-20
KR20060003875A (ko) 2006-01-11
MXPA05011063A (es) 2005-12-12
US20060217395A1 (en) 2006-09-28
NO20055367L (no) 2005-11-14
KR20060003876A (ko) 2006-01-11
GB0308968D0 (en) 2003-05-28
US20060287325A1 (en) 2006-12-21
US20060241124A1 (en) 2006-10-26
AU2004229179A1 (en) 2004-10-28
MA27731A1 (fr) 2006-01-02
JP2006523649A (ja) 2006-10-19
JP2006523650A (ja) 2006-10-19
MA27730A1 (fr) 2006-01-02
JP2006523651A (ja) 2006-10-19
CN1809355A (zh) 2006-07-26
NO20055368L (no) 2005-11-14
PL377858A1 (pl) 2006-02-20
WO2004091617A1 (en) 2004-10-28
IS8129A (is) 2005-11-15
EP1615642A1 (en) 2006-01-18
CO5700753A2 (es) 2006-11-30
RU2005135647A (ru) 2006-06-10
WO2004091616A1 (en) 2004-10-28
EP1653956A1 (en) 2006-05-10
ZA200508067B (en) 2007-02-28
IS8128A (is) 2005-11-15

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