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MXPA04004291A - Polimorfismos de un unico nucleotido en la gh-1. - Google Patents

Polimorfismos de un unico nucleotido en la gh-1.

Info

Publication number
MXPA04004291A
MXPA04004291A MXPA04004291A MXPA04004291A MXPA04004291A MX PA04004291 A MXPA04004291 A MX PA04004291A MX PA04004291 A MXPA04004291 A MX PA04004291A MX PA04004291 A MXPA04004291 A MX PA04004291A MX PA04004291 A MXPA04004291 A MX PA04004291A
Authority
MX
Mexico
Prior art keywords
single nucleotide
nucleotide polymorphisms
sites
dysfunction
diagnosing
Prior art date
Application number
MXPA04004291A
Other languages
English (en)
Inventor
Susan Wood Linda
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of MXPA04004291A publication Critical patent/MXPA04004291A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La invencion proporciona segmentos de acidos nucleicos del gen de la GH-1 que incluye lo sitios polimorficos. Tambien se proporcionan los cebadores y sondas especificos de alelos que se hibridizan a las regiones que flanquean estos sitios. La invencion tambien proporciona procedimientos para diagnosticar la disfuncion de la GH-1.
MXPA04004291A 2001-11-09 2002-11-07 Polimorfismos de un unico nucleotido en la gh-1. MXPA04004291A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34744801P 2001-11-09 2001-11-09
PCT/US2002/035719 WO2003042226A2 (en) 2001-11-09 2002-11-07 Single nucleotide polymorphisms in gh-1

Publications (1)

Publication Number Publication Date
MXPA04004291A true MXPA04004291A (es) 2004-08-11

Family

ID=23363738

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04004291A MXPA04004291A (es) 2001-11-09 2002-11-07 Polimorfismos de un unico nucleotido en la gh-1.

Country Status (8)

Country Link
US (1) US20030170679A1 (es)
EP (1) EP1451368A4 (es)
JP (1) JP2005508650A (es)
AU (1) AU2002360349A1 (es)
BR (1) BR0214017A (es)
CA (1) CA2466346A1 (es)
MX (1) MXPA04004291A (es)
WO (1) WO2003042226A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2498319A1 (en) * 2002-09-09 2004-03-18 Nautilus Biotech Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
US7998930B2 (en) 2004-11-04 2011-08-16 Hanall Biopharma Co., Ltd. Modified growth hormones
GB0600114D0 (en) * 2006-01-05 2006-02-15 Univ Cardiff Growth hormone variations

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1268404A (en) * 1985-03-15 1990-05-01 Antivirals Inc. Polynucleotide assay reagent and method
US5034506A (en) * 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5185444A (en) * 1985-03-15 1993-02-09 Anti-Gene Deveopment Group Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5075217A (en) * 1989-04-21 1991-12-24 Marshfield Clinic Length polymorphisms in (dC-dA)n ·(dG-dT)n sequences
US5424186A (en) * 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
DE122006000003I2 (de) * 1995-09-21 2011-01-13 Genentech Inc Varianten des menschlichen wachstumshormons
EP0790305B1 (en) * 1996-02-13 2002-04-24 JCR PHARMACEUTICALS Co., LTD. Mutant human growth hormones and their uses
US5856104A (en) * 1996-10-28 1999-01-05 Affymetrix, Inc. Polymorphisms in the glucose-6 phosphate dehydrogenase locus
US6946265B1 (en) * 1999-05-12 2005-09-20 Xencor, Inc. Nucleic acids and proteins with growth hormone activity

Also Published As

Publication number Publication date
US20030170679A1 (en) 2003-09-11
WO2003042226A2 (en) 2003-05-22
EP1451368A2 (en) 2004-09-01
JP2005508650A (ja) 2005-04-07
BR0214017A (pt) 2005-01-04
WO2003042226A3 (en) 2004-03-18
AU2002360349A1 (en) 2003-05-26
CA2466346A1 (en) 2003-05-22
EP1451368A4 (en) 2006-02-22

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