MXPA03011987A - Method for treating presbyopia by inducing changes in the corneal power and physiology. - Google Patents

Abstract

The present invention relates to a novel method for correcting presbyopia or tired eyes. The method is based on a mechanism for inducing a mathematical formula in the anterior surface radio of the cornea, which is different from that inherited by people and useful for providing them with the required vision at all distances without constantly using spectacles. The aforementioned process consists in producing a compound myopic astigmatism having a vertical axis. The following methods are useful for changing the curve of the cornea: 1) using a moulding lens after a refractive surgical technique, either Lasik, Lasek, PRK or any process in which the anterior layers of the cornea or sclera have undertaken a surgery, or any process that alters the refraction of the eyeball; 2) using a moulding contact lens and a boosting substance in drops, gel or the like when the inherited defect of refraction is moderated -6.00 gradations or less, or when the defect is reduced -3.00 gradations or less; 3 ) when the inherited refraction defect does not require optical correction for looking from far, but having indicia that the physiological process of presbyopia is occurring; 4) using the Dynamic and Interactive technique (DI) which alters the normal physiology of the cornea as well as the visual memory. Dynamical changes of the corneal and body physiology are induced according to the working needs and/or age variations presented during the natural process of the presbyopia. The method of the invention dynamically allows the corneal physiology to be altered without generating irreversible changes or anatomo-hystological complications in the eye. The corneal power is based on the fine and accurate perception of the images produced by the motor-brain-optical system MBOS. Said method includes a computer program which uses the following complete formula: CA (cerebral adaptation) + VM (visual memory) + OAS (Optical-anterior system) + MBOS (Motor-brain-optical system) so as to individualize the corneal power for both eyes. The technique of the method includes special designs of the moulding lens as well as boosting substances in drops, gel or the like, which promote changes in the collagen fibers, the hyaluronic acid, the percentage of corneal hydration and the normal parameters in the anatomy-histology and physiology of the cornea.

Description

METHOD FOR THE TREATMENT OF PRESBICIA INDUCING CHANGES IN POWER AND CORNEAL PHYSIOLOGY Field of the invention The present invention refers to an innovative method for the correction of presbyopia or tired eyesight. The method is based on a mechanism for the induction of a mathematical formula in the radius of the anterior surface of the cornea, different from the one inherited by the people and that allows them the near and far vision they require, without the constant dependence on glasses .

BACKGROUND OF THE INVENTION Surgical techniques for altering the curvature in a healthy cornea include Keratotomy, Keratomileusis by freezing, ALK (Automated Lamellar Keratomileusis), PRK (Photo Refractive Keratomileusis), LASIK (Lasers Assisted in situ Keratomileusis or Laser intra stromal Keratomileusis) or LASEK (Keratomiléusis epithelial laser) and currently scleral resections. All these surgical techniques are already well known in the field of ophthalmology. The aforementioned techniques use different methods to change the corneal curvature, however, all have limitations for the total correction of the refractive defect. Some techniques use diamond scalpel cuts that depend entirely on the manual dexterity and surgical experience of the surgeon or the laser beam or ablations with YAG Laser. Other more modern techniques can not resect the corneal or scleral tissue with the precision that is desired since there is always a residual mathematical refractive that does not allow to reach the desired vision by patients from near or far in the same surgical time. When the visual demands that the human brain requires, which in this application will be called visual memory® (MV®) and cerebral accommodation® (AC®), can not be met, physicians need to use one of the three alternatives that exist to improve the correction of the defect that could not be corrected, which are: 1) use glasses; 2) use contact lenses; 3) Make a retouch with another surgery. The limitations for the correction of myopia, hyperopia and astigmatism are innumerable. In addition, attempts to correct presbyopia have had even more limited results such as, for example, a) The one-eye myopiovision technique (mono-visual technique); b) techniques to provoke positive areas in the central area of the cornea by making changes in the peripheral curvature; c) scleral resection techniques to alter the rigidity of the sclera, ciliary tissue, zonula; and increase the accommodation power of the lens. Which have had limited results due to the lack of comprehensive understanding of the physiological behavior of the eye as the corneal stroma and the exact measurement of the mathematical power of the cornea, in addition to the total lack of control of surgical techniques. The limitations for the correction of presbyopia are the result of only treating a single region of the eye, trying to demonstrate that techniques without any control can produce positive areas in the area of the optic zone of the cornea or changing the position of the lens or its curvature, it can replace the near vision, without taking into account that the distance vision diminishes. These techniques also consider the mathematical calculations of the eye as if it were the schematic eye of Gullstrand, without correlating the vision requirements that each patient requires, which have been developed throughout his life. It is important to note that presbyopia, to this day, is known by experts in the field as the lack of accommodation of the lens. The accommodation is the consequence of a series of events that occur when having an object as a stimulus to see up close, producing: a) that the two eyes converge at the point that needs to be seen up close; b) that the pupil contracts; c) that the lens (lens) increases its diopter power increasing its curvature to be able to focus the images on the retina. The previous definition of accommodation does not completely correlate the brain functions that are necessarily going to make the required adjustments so that in an organized way all the reflex arcs can be made and thus the optical systems, cerebral and muscular of the eye and body, complement each other to make the accommodation, depending on the visual memory® and the cerebral accommodation® that correlate in this patent application. As the crystalline lens is the most important (in traditional concepts and known up to now) for accommodation due to its high dioptric power and thus being able to see it up close, most experts in the field have considered it as paramount and have focused on restore the loss of its power of accommodation and improve its function, when presbyopia begins after approximately forty years, by means of medications or surgical techniques. However, attempts to correct presbyopia in the cornea to date have been limited because the correlation between visual memory® and cerebral accommodation® has not been considered, as well as the limitation in the measurement of corneal power ® more accurately, which is one of the objects of the present invention. Refractive surgery has begun to use more sophisticated measuring devices to know the different parameters of the elements that contribute to the correction of presbyopia, such as the company Bausch & amp;; Lomb Surgical. However, these measurements are only approximations because it has been shown that the cornea has a similarity to fingerprints, and therefore with the measurements made can not specify the behavior of the response of the cornea and each anatomical region of the eye, so that it allows to predict the final post-surgical mathematical result, and consequently the success for the vision that is required near and far, without the help of glasses or optical support. The change of corneal curvature can also be done with other devices, such as the one used in Thermo coagulation (Holmium YAG Laser.), Proposed by Sand in US Pat. No. 5, 484, 442. Strictly speaking, this prior technique does not correct presbyopia. since it can only correct farsightedness and produce better vision from afar, but in trying to produce a corneal curvature that corrects presbyopia, this corneal curvature is altered in an unequal proportion that could cause corneal irregularities, causing astigmatism that could be more severe than hyperopia itself. In U.S. Patent Application No. US2003 / 0139737, filed January 24, 2002, by JTLin, it is suggested that prior art known up to that date does not really solve the intrinsic problems of the presbyopic patient caused by aging. , where the lens or lens loses its accommodation as a result of the loss of elasticity ad due to age. However, the real problem is to solve the natural defect of presbyopia, caused by lack of accommodation of the lens and not of the cornea as suggested by J.T.Lin, by the natural loss of elasticity after approximately 40 years of age. All the prior art that is mentioned in the application No. US 2003/139737 of J.T.Lin, suggests that the known methods to change the corneal curvature are not the alternative for the correction of presbyopia. However, J.T. Lin proposes a method for the correction of presbyopia by increasing accommodation in presbyopic patients by changing the intrinsic properties of the sclera and ciliary tissue to increase the accommodation of the lens without changing the curvature of the cornea. This method does not solve the problem of presbyopia since it does not consider that each of the structures are different in each patient and that in the future the patient would begin to feel a regression of the corrected defect and therefore it is only a good attempt or mathematical approach, but unable to achieve the mathematical changes so fine and precise that are needed for the correction of eyestrain or presbyopia, without taking vision away from patients and causing complications. The alternative for the correction of presbyopia (tired eyesight) is the change of the power and physiology of the cornea in a dynamic, continuous and gradual (dynamic and interactive) way, and not only considering the calculations of the formulas of optical physics and well-described and traditional to find the calculation of corneal power®, which is an object of the present invention, or of the total power of the eye, as are for example the optical physics formulas of the schematic eye of Gullstrand, mentioned later, or the Littman formulas or the formulas pronounced in the application of the US patent No. US2003 / 0139737, JTLin, where the aim is to describe how each of the structures of the eyeball is calculated with its refractive indices and differentials. The formula proposed by J.T. Lin considers an eye of plastic and constant factors of optical surfaces like that of crystals, and therefore the supposed image at the level of the retina can be thought, that it will be sharp. However, in reality no eye surface has the same thickness, curvature or distance (see Bausch &Lomb Surgical presentation documents, ORBSCAN®PRESENTAT ONS, October2000 Edition). The existing prior art does not take into account that the mathematical calculations in the theory are "exact", but that nevertheless they can not calculate the exact formula of the human eye or correct presbyopia, due to the simple fact that the eye is an organ living. Under this last consideration, it is to be understood that the most sophisticated mathematical formulas can not calculate the displacement of the lens (lens) or the change in its curvature because in each patient the elements described are different and the lack of control in scleral resection . In the US application No. 02003/0139737, it is also suggested that the ablations are in all cases equal and regular in depth and length and width of the resection of the scleral tissue. It also suggests that in all patients' eyes the sclera has the same rigidity as the internal structures of the eyes, such as the ciliary body, ciliary, zonula and crystalline muscles, and they must respond as in the theoretical scheme, which it is not possible since in a single individual all these parameters are completely different, so the technique depends totally on the manual skill of the surgeon and his experience, in addition to the variables of. each eye on the same individual, so this is only an approximation since in the short term patients will again use glasses to see up close. The proposals and recent investigations, including the previous related art, only contemplate the lens and its power of accommodation, as an isolated mathematical system, therefore do not correlate all the systems that are interconnected and that even in the application US 2003/0139737 in paragraph

[0047] they are cited. Therefore, the present invention proposes a method for altering the corneal physiology by means of a dynamic and interactive technique® (DI®) in which the patient is responsible for guiding his doctor with full awareness and in an intelligent way regarding your needs related to the distance of vision you need depending on the age and the work you do or could do in the future. To achieve such fine changes in the corneal curvature, it is necessary to have instruments that can measure with greater precision the mathematical power of the cornea and the eyeball, since the formulas proposed by all researchers as Barraquer, Littmann, Shaschar, Throton and JT Lin, propose only theoretically calculations that are mathematically accurate, without taking into account the important differences that each eye has separately in each of its structures. As an example we can take a globe where we are only trying to demonstrate the limits of the countries and some differences in the seas, mountains, lakes etc., but in no way can you prove the immense irregularities in the dimensions of each one of these structures. Correlating this concept and although the eye measures only approximately 23 millimeters approximately in its antero-posterior diameter, also its differences in the dimensions of its different structures are very important, this is why the optical devices used to this day, which they are only calibrated to measure optical surfaces with steps of 0.25 diopters, it is impossible to measure the refractive defect of the cornea with the precision that the brain demands, and instead of the specialist measuring a myopia of 1.00 diopter, it should be able to measure 0.938 diopters and the axis of astigmatism instead of measuring it at 100 degrees should be measured at 99.38 degrees. Only in this way could the defect be measured prior to the techniques that are the subject of this patent, and achieve the exact change and that demands the visual memory®, both for near and far vision.

One of the objects of the present invention is to provide novel methods and techniques for overcoming the aforementioned disadvantages, without using any type of surgery by inducing a change in corneal power, for the correction of presbyopia, with or without combinations of defects. of inherited refraction. The invention also aims to demonstrate that the dynamic and interactive technique® (DI®) is one of the best alternatives for the correction of presbyopia with the advantage over other surgical techniques that can be repeated as many times as necessary according to the development of age as well as change in the work activities of patients. Yet another objective of the present invention is to demonstrate the correlation of mathematical corneal power with visual memory® (MV®) and cerebral accommodation® (AC ©) which are what demand the necessary and precise formula so that the mathematical power of the cornea supla replaces the deficiency of the accommodation power of the lens called crystalline lens, which is the one that focuses the images closely before the 40 years approximately. It is also another object of the present invention to provide the parameters for mathematical calculations to achieve individualized corneal power. In the techniques that are provided in the present application, specially designed contact lenses are used so that their different base curves in the radii of posterior curvature, anterior, as well as in their diameters of optical zone and peripheral zone, change or induce the corneal power ® necessary by dynamically altering the corneal physiology and molding it gradually, uniformly and constantly. The use of "hard or soft" contact lenses that commercially exist is not excluded. Still another objective of this application, is to use a contact lens (s) moldeador® (es) (LCM®) so that instead of performing another surgery that doctors "call retouching", you can correct the residual mathematical defect without surgery. This residual post-operative defect is due to the lack of an accurate measurement of the refractive defect presented by the patient before surgery, so the only way to correct the remaining remnant is to gradually change the curvature of the cornea until the The same patient finds his corneal power according to his needs and visual memory®. In this respect, US Pat. No. 6,582,076, by Jeffrey H. Roffman et al, describes a contact lens for permanent use to correct near and far vision and even irregularities of the cornea (astigmatism), but does not induce any change in the radius. of anterior surface of the cornea that produces the lens of the present invention together with the use of potentializing substances® in the form of drops, semi-solid gel or similar. It is another object of the present invention to provide potentiating substances® in the form of drops, semi-solid gel or the like, and a method for applying the same which help the change in corneal power, to stabilize or improve or increase the change of the corneal curvature, in the cases of: 1) after any refractive surgery; 2) without surgery in patients with moderate or low refractive errors; 3) patients who, after 40 years of age, wish to improve their vision closely by presenting symptoms of presbyopia or eyestrain. Still another object of the invention is to provide a portable ergonomic kit or case containing a lens reservoir, shaping lens, potentiating substance® in the form of drops or semi-solid gel, or the like, cleaning substances for the contact lens, lubricating substances, table to identify the appropriate and instructive lens for its use. With the techniques described here, the results of any refractive surgery can be refined or improved even in corneas that are going to be operated for the first time or in corneas that previously have already been operated taking into account or based on the stromal slip described later. It is important to note that with the techniques described in this, the post-surgical mathematical result of the patient is no longer of vital importance, unless the vital organs of the vision have been damaged, since when shaping the cornea it is possible to reach the vision needs of each patient. An important aspect of the invention is to start with the treatment to improve the corneal curvature with LCM® in the immediate post-operative of any type of refractive surgery, based on the scientific stromal slide® proposed in the present application by the inventors. . It should be understood that the following full description of the invention can be illustrated in other forms and variations without departing from the spirit or essential characteristics thereof. Accordingly, the embodiments described herein should be considered only as illustrative and not as restrictive of the invention.

BRIEF DESCRIPTION OF THE INVENTION The mechanism for carrying out the invention is based on the induction of a mathematical formula in the radius of the anterior surface of the cornea, different from that inherited by people and that allows them to see near and far. that they require without the constant dependence on glasses to see up close. The mechanism comprises producing a compound myopic astigmatism with vertical axis (horizontal or oblique), according to the needs and experiences developed by visual memory® during the patient's life. The methods used here are to change the curvature of the cornea by means of: 1) molded contact lenses® (LCM®) after some refractive surgical technique either Lasik, Lasek, PRK, or any process in which the anterior layers of the cornea or sclera are involved, or any alteration or change that is provoked or induced in the refraction of the eyeball; 2) contact lens and potentialized-ras® substances in the form of drops, semisolid gel or similar, when the inherited refractive error is low to moderate, and in the case of operated patients, the healing process is already completed or in patients who are not undergoing surgery but who are already starting due to their age to present the symptoms of tired or presbyopic sight. The dynamic and interactive method or technique © (DI ©) consists of altering the normal physiology of the cornea together with the visual memory® and the cerebral accommodation®, in order to obtain the necessary corneal power® and achieve the near vision that is needed. requires The method in dynamic form can alter, uniformly, gradually and controlled the physiology of the cornea, without producing irreversible changes or anatomo-histological complications in the eye. The corneal power® is based on the fine and precise perception of the images that are received by the optical-cerebral-motor® system (SOCM®), during the development of the activities of each individual and throughout his life, so that This is the one that will be required after any refractive surgery. The use of contact lenses with substances that potentiate the mechanical pressure factor exerted by the LCM® on the surface of the cornea makes it possible to obtain the appropriate mathematical formula.

Brief Description of the Drawings The embodiments of the invention will be better understood by means of the figures, which should be interpreted only as illustrative and not as limiting thereof. FIG. 1 illustrates the schematic eye of Gullstrand which belongs to the previous technique but which nevertheless must be taken into account by including the main elements in the formulas for the calculation of corneal power and the power of the eyeball used to carry out the techniques proposed here. FIG. 2 illustrates the conoid of Sturm used to demonstrate the formation of images by a sphero-cylindrical lens (a right-handed one in the technique interprets the sphere as myopia and astigmatism the cylinder), which also belongs to the previous technique. However, the principles described there will also be used as a basis to explain the novelty of the invention. FIG. 3 is a photograph showing the differences that exist in the thickness and radius of curvature of the different regions of the eye FIG 4 is a schematic figure showing the stromal slip.

Detailed Description of the Invention The following terms will be used throughout the description, so its definition is included. Understand as: 1. Corneal power®: To the mathematical value expressed in diopters of the refractive power of the cornea or in millimeters of the radius of curvature. To measure it, the anterior surface radius, the corneal thickness, and the posterior surface radius are quantified. Induction in the change of corneal power: The mathematical change expressed in diopters or in millimeters of radius of curvature, of the value of the anterior surface radius of the cornea, which must be induced, to reach the dioptric value necessary to change the refractive power of the cornea and thus produce the near and far vision required by each patient, in both eyes separately. Visual memory®: The accumulation of images in the brain, which are perceived through the optical-cerebral-motor® system (SOCM®) throughout life, and which by natural selection are necessary and important for the daily routine of each individual, accepting therefore, as natural and normal, the point of dispersion in the retina [PSF, for its acronym in English], when this image is within the physiological limits to be tolerated by visual memory®. Cerebral accommodation: All the functions that control the movements of the muscles through chemical-electrical impulses, so that with the interconnections of the cerebral-motor-optics systems (SOCM®), the necessary and precise changes of the whole body are made, especially of the eye, to be able to focus the images and see well up close and far, decreasing the point of dispersion in the retina [PSF]). Dynamic and interactive technique®: The method that allows to induce or alter the normal physiology of the cornea based on visual memory® and cerebral accommodation® to obtain the necessary corneal power and achieve the near and far vision that is required, decreasing or neutralizing the point of dispersion in the retina [PSF]. Contact lens molding® (LCM®): To the contact lens specially designed to induce the change in corneal power®. Potentializing substances®: Substances either in droplets or semisolid gel or similar that by their chemical action, alter the physiology of the cornea, changing the forces of the corneal lamellae, allowing the change in its curvature, to be able to mold the corneal stroma . Including any hypotonic or hypertonic substance. Stromal sliding®. To the displacement of the corneal stroma after any refractive surgery on the cornea, due to the separation of the lamellae during the cutting or ablation of the tissue, allowing during the healing process of the corneal wounds to slide to flatten or curl still in higher proportion corneal curvature. Transient permanent technique®: means that changes in the corneal curvature for the correction of presbyopia can not be permanent because the lens changes its dioptric power continuously according to the age of the patient and changes can be made according to the distance of work developed by the patient. For a better understanding of the definition it is necessary to keep in mind the concept of fuzzy mathematics. This concept is already well studied and accepted, and proposes that there is an immense infinitesimal difference between zero and one, and therefore numbers are very diffuse, so for this it is very individualized for each patient or brain or visual memory or cerebral accommodation, since the concept of 0.723 D, a patient conceives it very well and for another needs corneal power of perhaps 0.723332211 D). 10. Anterior-optical system®: The set of anatomical structures of the eye, corresponding to the anterior segment. 11. Optical-cerebral-motor® system (SOCM®); To the set of anatomical structures of the body that through interconnections interact to make the muscular adjustments of the whole body to achieve the appropriate positions and to activate the reflex arcs to achieve a good view of near and far, besides interconnecting all the muscular actions to effect the necessary changes of the body that are related to the vision and that are triggered to make and carry out the activities of each individual (for example, walking, driving, etc.) 12. Dispersal point: The image of an object or visual stimulus that characterizes an optical system. The four groups of patients that can be treated with the proposed technique, without being limiting, are: 1. Patients who have good distance vision and who never find glasses or contact lenses required to see from afar, and who arrive at the age of presbyopia, with the consequent decrease in near vision. 2. Patients who have an inherited refractive error, with the need to use glasses or contact lenses and who wish to correct the defect in any of the different distances of vision: far, intermediate or close. 3. Patients who are undergoing refractive surgery to correct inherited defects, and who are left with a mathematical residual that does not satisfy their needs for far, intermediate or near vision. 4. Patients under 18 years of age in whom the inherited refractive errors should be corrected, so that when they reach the age of presbyopia, the changes in the corneal power can be minimal and therefore be accepted by the visual memory® and the cerebral accommodation® without any discomfort. To aid in the understanding of the invention, it is necessary to describe the schematic eye of Gullstrand and the conoid of Sturm. Figure 1 shows the schematic eye of Gullstrand that includes the elements for calculating corneal power®. This calculation is based on the anterior surface radius, corneal thickness and posterior surface radius. The initial power of the anterior surface radius of the cornea is obtained by measurement with the keratometer. The reading can be made directly in diopters only if the refractive index used by the keratometer used is the same as we will use in the calculations. If this is not the case, you should read the initial radius (Ri) in millimeters, and convert this value to diopters, with the appropriate refractive index, using the formula: (? -? '). 1,000 1,332-1,000 332 D = =. 1,000 = = Di R R Ri where D = Diopters; n = Refractive index of the air; n '= Refractive index of the cornea; R = Anterior surface radius; Ri = Initial radius; Di = Initial Diopter; 1,000 = Index of air refraction QUANTIA OF THE REFRACTION DEFECT The amount of the mathematical defect is measured in the corneal vertex with the following formula: From Dv = x. From 1 1,000 where Dv = Diopters to vertex; De = Diopters correction; Then the final diopters are calculated using the following formula: 332 Df = Di + Dv = + Dv Ri where Df = Final Diopter; Di = Initial Diopter; Ri = Initial radius; and Dv = Diopters to vertex.

FINAL RADIUS The final radius is calculated in millimeters instead of diopters to facilitate the calculation in some measuring equipment, by means of the formula: 332 Rf = 332 + Dv Ri where Rf = Final radius; Ri = Initial radius; Dv = Diopter to vertex.

CORNEAL THICKNESS Corneal thickness is calculated based on the difference between the anterior surface radius and the radius of the interface, that is, the ablation obtained in the anterior stroma.

POSTERIOR SURFACE RADIO The posterior surface radius is equal to the final radius minus the post-surgical stromal thickness (Rsp = Rf-Ed). The calibration of the optical devices is carried out for example with the calculations of the schematic eye of Gullstrand, and when there is a change in the constants, it is no longer possible to measure the corneal power correctly, in most of the optical and automated devices as per example the auto-kerato-refractometer. Therefore, in order to perform the exact mathematical calculations it is necessary to use devices that measure the anterior surface radius, the corneal thickness and the posterior surface radius, such as ORBSCAN II, commercially available from Bausch & Lomb Surgical. In addition to these optical devices in general, measure the corneal power in very thick steps of 0.25 D, which causes errors for the correct measurement of the patient's vision and therefore obtain the mathematical formula for the calculation of corneal power® that is requires to achieve near and far vision. In the present invention, the induced corneal power is considered with a sphere (myopia) and a myopic cylinder (astigmatism) of 0.100 diopter up to 0.999 diopter, which is the recommended interval to be able to correct the near vision without significantly diminishing the vision from far. The quality and visual capacity will be related to the pupillary diameter. The complex: crystalline, zonula, ciliary muscle, ciliary body and sclera is considered in the dynamic and interactive technique since they induce changes in the ocular globe at different ages, combining their dioptric power. Once the aforementioned intervals have been verified, we proceed to interact with the patient regarding his vision needs for far and near. This stage is based on the fact that the patient is the one who really measures their corneal power to decrease or neutralize the point of scatter in the retina (Point Spread Function (PSF)), to which the ophthalmologist or person experienced in the field of the vision could be approximated by using a mathematical formula that is described later, and complementing it with the cerebral accommodation and visual memory, which allow the patient to guide the specialist to flatten or flatten the cornea depending on whether the patient needs to have good vision from afar or up close In order to carry out the bulging or flattening of the cornea, the dynamic and interactive technique makes use of shaping lenses together with potentializing substances® (e.g., drops or semi-solid gel or the like). Cerebral accommodation® could be understood as a natural process, however, as explained above to achieve this cerebral accommodation © external light stimuli are needed and consider the concept of diffuse mathematics, that is to say, all the images perceived of the environment both near and far and that are considered by the cerebral accommodation® as important and necessary, in order to be able to activate or force to the maximum the functioning of said brain accommodation®. Once the images are captured they are sent to a memory bank, ie the visual memory®, which stores such images. The visual stimuli during the normal development of each individual vary, reason why the cerebral accommodation® will take vital importance for the development of activities or functions that the individual apparently performs without being aware of them but which, nevertheless, are already known images. and recorded in the visual memory® and that can perform the necessary visual and corporal accommodation mechanisms. As mentioned earlier, the dynamic and interactive technique uses brain accommodation®. Brain accommodation® is based on the functioning of the brain, specifically that function that allows the formation of images through the visual organs and the execution of muscular actions to initiate and complete the reflex arcs that interconnect the optical and cerebral systems. Therefore, the explanation of the functioning of the brain, in detail, will not be described in the present invention since it is well studied in the field of neuro-physiology. At the moment when the balance (beginning of presbyopia) is disturbed between the ocular globe (crystalline) and the nervous system (cerebral accommodation®), the clear transmission of an image to focus becomes very difficult to associate and interpret by memory visual®, and as a result the patient will need help with glasses to see up close. In the dynamic and interactive technique®, the procedure to achieve a corneal power required by the patient based on the visual needs of the patient is also contemplated. The technique includes the modification of the corneal power® because this will now be the main element and director to achieve the vision of near and far that the patient requires and thus achieve the requirements of visual memory® and continue with the help of brain accommodation®. Therefore, adding all the above-mentioned factors, only a small change in tenths of a millimeter of the anterior curvature radius of the cornea will be needed, which is also part of the dynamic and interactive technique®. The induction of corneal power is carried out in the corneal stroma by changing the anterior surface radius of the cornea. The stages considered in the dynamic and interactive technique® to perform said induction in the corneal power are the following: a) The age and work needs of each individual must be taken into account; b) Induce the change of the PC (corneal power®) in the anterior surface radius in the eyes through the LCM® and, if necessary, use potentializing substances®; c) Induce the change of the PC with the LCM® and if it is the case, use potentializing substances® in the form of drops, semisolid gel or similar, in a single eye as long as the contralateral eye has the mathematical formula that by inheritance produces it the vision of far and near that the individual requires for his work needs and according to his age. d) Induce the change of the PC with the LCM® and if it is the case, use potentializing substances® in the form of drops, semi-solid gel or similar, in the above surface radius according to the formula proposed in the present description, which it is composed of a myopic astigmatism with vertical axis (or if it is the horizontal or oblique case). The formula comprises: i) Induce the change of the PC in the anterior surface radius with a value in a myopic interval (sphere) from 0.25 D to 0.75 D, and myopic astigmatism (cylinder) from 0.25 D to 0.75 D, according to to the age and needs or working distance of the individual to be treated. By inducing the change in the PC in the anterior surface radius, greater than 1.00 D in myopia (sphere) and more than 1000 D in astigmatism (cylinder), near vision increases; but it significantly diminishes vision from afar. ii) Induce the change in the PC in the anterior surface radius, with an axis of vertical myopic astigmatism, (on special occasions the patient can request for their visual needs horizontal and / or oblique axes). For example in the case of vertical astigmatism with less than 45 ° with respect to verticality (90 °). As previously mentioned, the devices that currently exist that are used to measure the value of myopia and astigmatism, do not measure the value of the anterior curvature radius, corneal thickness and radius of curvature of the cornea with precision, this being the reason why quarter (0.25) diopter measurements are considered in the proposed formula of the present invention. e) Carry out the calculation of the PC with a sphere (myopia) and a myopic cylinder (astigmatism) of 0.100 diopter up to 0.999 diopter, which is the recommended interval to be able to correct near vision without significantly diminishing distance vision f) Consider the best axis of astigmatism required by each patient for close vision, individually, considering each eye separately. g) The change in the PC with everything and its axis will be the one that visual memory® demands of each individual. h) As the visual memory® is unique for each individual, the patient is the one who should guide the expert in the matter to be able to make the necessary change in the PC in order to have a good vision up close. i) Use contact lens molding (LCM®), which will exert mechanical force on the anterior surface of the cornea, inducing the change in the PC required. j) Use LCM® manufactured with the known procedures but taking into account the required specifications according to the dynamic and interactive technique®, especially when it is necessary to use hard LCM®. k) Once the LCM® is placed, add potentiating substances® to increase the mechanical strength of the LCM® and together produce the permanent transient effect® for the change of the PC in the anterior surface radius of the cornea. Potentializing substances® in the form of drops, semisolid gel or similar can be applied frequently and depending on the frequency of their application, the corneal lamellas will present a transient permanent molding faster. However, the application of the drops at 3 hour intervals is recommended. The potentiating substances can be hypotonic or hypertonic, depending on the patient's requirements, that is during the work day, hours of rest or sleeping. Considering the previous elements, the dynamic and interactive technique® will allow us to obtain a customized formula for the PC to produce the vision requirements that the patient needs. The mechanism of action of the contact lens molding: a) After any refractive surgical technique that causes spaces between the stromal lamellae either by cuts, resections or by ablations, there will be a stromal sliding that causes the stroma to slide towards the periphery to correct more myopia defect or slide towards the corneal center to correct more hyperopia or presbyopia (see figure 4). b) When the LC ® is used plus the potentializing substances® in the form of drops, semisolid gel or similar, the corneal stroma is altered, together with all its anatomical and histological structures, inducing changes in the mechanical forces of the lamellas as well as inducing changes in the cells and their collagen proteins and in the hyaluronic acid found in the corneal stroma, so that by exerting external mechanical forces, the corneal lamellae can be molded in the way the LCM® is designed. c) When shaping the corneal stroma, the surface of the cornea also becomes more uniform. As is already well known, even normal corneas have irregularities in their surface as shown by ultrasound (isometric tomography), so that by making the surface of the cornea more uniform, visual acuity improves in quantity but above all in the quality or sharpness of the images. For the calculation of the LCM® the most flat eratometry is taken, although some right-handed in the matter could use for the calculations the more curved keratometry or an average of the two, so that based on this corneal curvature the necessary calculations are made to flatten or encurvar, the anterior surface radius and thus correct the refractive defect that is required, as well as induce the necessary corneal power for the correction of presbyopia. The base curve of the LCM® is calculated to induce the change in corneal power that is required for each eye separately. The base curve of the LCM® is calculated starting with a more flat or more curved diopter depending on the refractive error that is required to correct. The peripheral base curve is calculated, depending on the adaptation of the LCM® calculating 0.5 of a millimeter of radius greater than that of the central zone. The diameter in the specially designed LCM® is approximately 9.5 mm to 10.6 mra. The power of LCM® is calculated being as close as possible to the refraction required by the patient to make their activities as comfortable as possible. During the adaptation of the LCM® if the vision is not the best to continue with your activities, it will be complemented with some glasses for the satisfaction of the patient while the objective of improving the sight is reached. Once the LCM® has been adapted, all the optometric measurements are carried out in detail to confirm that the LCM is adequate, for example visual acuity with the LCM® for near and far, the exact distance to see with satisfaction readings printed as the size of a newspaper at a distance of 40 to 45 cm, orthotypes, measurements of eratometry, objective and subjective retinoscopy, adaptation diagram of the LCM®, movement of the LCM®, comfort to the LCM®. Subsequently, the changes that should be induced in the corneal power in the following weeks are calculated. If the patient has not recently undergone refractive surgery, then potentializing substances® should be used in the form of drops, semi-solid gel or similar. The LCM® used in the present invention can be soft or hard. If a soft LCM® is used, a more positive or negative curvature is induced in the cornea, in addition to lessening the discomfort in the eye in patients who first use contact lenses. If a hard LCM® (permeable gas) is used, mechanical pressure will be exerted. In order to know the results of the dynamic and interactive technique®, periodic reviews are suggested every week for 8 weeks after having placed the LCM® and using the potentializing substances®, if necessary, so that the patient can be evaluated again and confirm the expert. if you are satisfied with the results obtained. If the patient is satisfied then the use of the LCM® and the potentizing substances® in the form of drops, semi-solid gel or similar is suspended until for some reason the patient changes his work habits or that by age the eye has undergone the modifications disorders by altering brain accommodation® and visual memory®. As previously mentioned, one of the most important stages of the dynamic and interactive technique® is that the patient is the one who guides the specialist or expert to achieve the quantity and quality of vision that he or she perceives and that visual memory® accepts . Therefore, according to the information provided by the patient and the results obtained from the measurements of corneal power induced, as long as the patient wishes, if his distance vision is better than close up, the radius must be routed of anterior surface of the cornea (both in the sphere and in the cylinder); if the patient has better near vision than from far away, the anterior surface radius of the cornea should be made flatter (both in the sphere and in the cylinder); if the image is distorted, it should induce a change in the axis of astigmatism (cylinder), so as to improve vision, if the patient wishes. With the assessment of both the patient and the one made by the specialist regarding corneal power, the decision is made whether to continue or not with the same characteristics of the LCM® originally used or if it is substituted by another, which is calculated taking into account the changes that were induced in the corneal power® considering again the measures of the curvature with the Keratometro so that with the flatter Keratometry, although it could use "for the calculations the keratometry more curve or an average of the two, the LCM is calculated ® that is required Another important characteristic of the dynamic and interactive technique® is that you can change the corneal power® to improve the mathematical result after any refractive surgery, so in recently operated patients the change in power can be induced corneal® and refine or improve even more the result of the surgery, which was intended to correct the inherited refractive error, for example myopia a, hyperopia with or without astigmatism. As already mentioned in this patent application, after any refractive surgery there is always a mathematical residual, which with the dynamic and interactive technique® can be corrected or improved to achieve the vision that the patient requires due to the demands of the patient. visual memory® for correct far and near vision. During the first four weeks, which is the time it takes to complete the healing process of corneal wounds, changes in corneal power can be induced by external pressure on the cornea with the help of the LCM®, which changes the anterior curvature radius of the cornea by means of the stromal slip®, so that the errors of exact measurement and the complications caused by the lack of experience of the specialist who performed the surgery, can be corrected. Another important characteristic of the dynamic and interactive technique® is the total change in the surgical approach of the specialist towards the patient, since with this technique post-surgical defects of any refractive surgery can be improved or corrected. As a result, surgery becomes even safer and more effective, becoming a necessary and obligatory complement for any refractive surgery. The corneal® power required by visual® memory can be changed or refine the techniques described herein by the contact lens moldeador® (LCM®) after the first 24 hours postoperative. The technique includes the special design of contact lenses, potentializing substances® in the form of drops, gel or similar that help the changes in corneal lamellae, collagen fibers, hyaluronic acid, the percentage of corneal hydration and as a consequence of the normal parameters in the anatomy, histology and physiology of the cornea. It should be noted that the potentializing substances can be hypotonic or hypertonic depending on the specialist, since the substances can obtain similar results. Therefore, based on all the elements previously considered, the mathematical formulas for correcting presbyopia with the method of the present invention are: 332 Rf = † ^ sphere and visual memory cylinder 332 + Dv Ri 332 Df = Di + Dv = + Dv + Desfera and visual memory cylinder Ri It should be noted that the calculations for the manufacture of the LCM® can be made through a computer program, which should be as simple as possible and based on all the aforementioned and described elements to obtain the results in the fast way . Therefore, although said program is not described in the present invention, it is to be understood that it can be considered as being described and claimed. In patients who are already presbyopic and require refractive surgery, the proposed mathematical formula of a composite myopic astigmatism with a vertical (or horizontal or oblique) axis must be induced so that their visual memory® begins to accept the new images and together with the accommodation cerebral © train and educate the patient to changes in their near vision habits. The potentializing substances® in the form of drops, gel or similar are used to change the lifting forces of the lamellas and thus shape the stroma with a new curvature, modifying the anterior surface radius of the cornea. Different chemical substances have been used for the correction of inherited mathematical defects, anatomical, age-related degenerations or diseases of the cornea, which are widely known in the prior art by experts in the field, or also in techniques Ophthalmological routine surgery. Hyaluronidase (or similar) is an enzyme known for decades, in addition that in ophthalmology are already well known their effects in combination with hyaluronic acid, which works as the cement between the corneal lamellae. ? In this regard, the inventors have used the combination of drops based on hyaluronidase (or similar) and hypotonic or hypertonic in different concentrations to avoid corneal damage finding that only using a hypotonic or hypertonic agent at concentrations known in the field of ophthalmology, get the necessary changes to mold the corneal lamellae and make the changes in the corneal power that are required permanently transient®. However, the potentializing substances® in the form of drops, gel or similar can be combined with anesthetics to avoid the common discomfort of LCM®, especially in patients who had never used any type of contact lens, enzymes, lubricating drops with different concentrations to lubricate the surface between the cornea and the LCM® and improve the comfort for its use during the time necessary to achieve the molding of the corneal stroma. It should be understood that for one skilled in the art also use in the form of drops, semi-solid gel or the like, will be obvious. Another combination of the potentiating substances® in the form of drops, gel or similar is with enzymes that act at the level of the bonds of the lamellas and in their own structure, besides altering the stromal hydration and the corneal thickness altering therefore the forces of Support of corneal lamellae. Another important characteristic of this patent application is that the LCM® can be manufactured including the potentializing substances® in the form of drops, gel or similar integrated in it, so that the potentializing substance® is constantly released in the form of drops , gel or similar, achieving the necessary molding of the stroma resulting in the change in the corneal curvature, to achieve the corneal power required. It should be noted that the main components, i.e., molding contact lens®, lubricating substance, cleaning substance and potentiator® in the form of drops or semi-solid gel or the like, can be included in an ergonomic case with instructions for use. FIG. 2 is the conoid of Strum which mathematically shows that the circle of least confusion produced by a sphero-cylindrical lens (cornea in the human eye) is the point at which all the light beams that cross through it are concentrated. However, the conoid of Strum considered the sphero-cylindrical lens as a smooth and uniform surface as if it were a glass or plastic. In addition to the above, ophthalmologists continue to refer to compound myopic astigmatism as a bad solution for the correction of presbyopia, since they are limited to thinking that two images will be produced at the level of the retina and therefore and obligatory Patient can not see well with the myopia and astigmatism that is going to induce him. Ophthalmologists or optometrists also perform measurements based on the two planes of the Sturm conoid and in the circle of least confusion. However, as it should be interpreted, it is in a different way, which involves one of the points of the inventive step of the invention. The light rays that form any image at the level of the retina can be interpreted by: a) para-axial optics, which consists in considering the measurement of a small central area of the cornea and in the apex or axial axis, including only to the rays near a central ray called the power axis, and can not predict aberrations in the images except astigmatism and refractive errors such as myopia. The calculations of the para-axial optics are relatively easy and can be done by hand or with a calculator. b) They also perform calculations based on geometric optics, which has the limitation that it does not consider light as wavelength, and which uses the propagation of light as a ray (a straight line in a uniform medium or with indexes). of constant and equal refraction). The method for the calculation of the geometric optics consists in the tracing of the rays and needs a computer. c) The most important and fundamental theory is that which incorporates optical physics, which treats light as "waves", this being the theory currently known that predicts wave interference and diffraction (that is, when surfaces that pass through the waves have different radii, thicknesses and / or refractive indexes, such as the cornea, crystalline and all the elements of the eye). Physics-optics calculations are very difficult. However, this physical optics does not consider the irregularities of the retina and the differences in radii and thickness of each intervening element and its differences in the refractive indexes in each eye separately, and therefore this calculation also has inaccuracies. With the dynamic and interactive technique®, the aforementioned disadvantages can be corrected, since this technique considers, with visual memory and cerebral accommodation, the point of dispersion in the retina (PSF), since as shown in the maps of isometric topography (see figure 3 taken from COLOR ATLAS OF CORNEAL TOPOGRAPHY, INTERPRETING VIDEOKERATOGRAPHY by Yaron S. Rabinowitz, et al, IGAKU-SHOIN Medical Publishers, Inc., page 65) both the anterior surface of the cornea and the posterior surface have a completely irregular shape so that it is only possible to achieve the circle of least confusion (or dispersion point (PSF)) that approaches the sharpest possible, by uniformly returning the anterior surface of the cornea, which is achieved through of the LCM®. By uniformly returning the anterior surface of the cornea and induce the change of corneal power that the patient requires, his visual memory® is the one that will guide him to obtain the desired vision from near or far As mentioned in the previous lines, all the corneal surfaces are different at all points in both the radius of curvature and corneal thickness, so the circle of least confusion and the point of scatter in the retina (PSF) is more blurred than calculated. In patients who have not needed glasses for most of their lives or contact lenses, it is because the inherited defect is very small for example, myopia of 0.690 diopters and astigmatism of 0.712 diopters (in current measures of myopia of 0.50 D and astigmatism of 0.75 diopter), so the brain with visual memory® and with cerebral accommodation® including the optical-cerebral-motor® system, can compensate the refractive error with the muscles and areas of the eye that allow the approach or accommodation of the change that takes place in the anterior surface radius. According to what is described throughout the present invention, the circle of least confusion that in the human eye is found in the retina, does not correspond to a completely uniform and neatly circular circle in its circumference, even in an eye inside. normal limits (mathematically), because all the anatomical irregularities of the cornea, which produce an infinite number of very small but different impossible foci calculate, which is further complicated when all these tiny or slight irregularities of add each of the anatomical regions of the eye. It should be noted that during a Lasik surgery the corneal disc is lifted and the laser beam is applied to produce the ablation. In other surgical techniques that perform striations or ablations of the stroma, as in the Lasik technique, it is allowed with the space of the resected tissue that the corneal disc, in Lasik or the stroma in the other surgical techniques, can be slid. The dynamic and interactive technique® makes use of this stromal slip property® caused by the ablation so that with the LCM®, and if it is the case, the potentializing substance® in the form of drops, gel or similar, is carried out as in the present invention is known as stromal slip®, which allows the cornea to bulge or flatten according to the LCM® used. When using only the technique contact lens after a refractive surgery can notice the estromal® slippage that the entire surface of keratectomy where only tenths of a millimeter or thousandths needed to correct the mathematical residual defect surgery and achieve low to moderate the dynamic technical and interactiva® MV® refraction that requires both eyes, for example in the myopic sphere D 0567 and in the myopic astigmatism 0.682 D, with an axis 122.5.

The corneal disc moves towards the periphery to correct more myopia, flattening more the anterior surface radius or moving towards the corneal center to improve hyperopia or presbyopia by bulging the anterior surface radius (see "REFRACTIVE SURGERY OF THE CORNEA, Instituto Barraquer de América, Bogotá, Colombia 1999, page 171) The stromal slip formula is already developed in "REFRACTIVE SURGERY OF CORNEA, Barraquer Institute of America, Bogotá, Colombia 1S99, page 171).

Although all the features and fundamental features of the present invention have been described here, with reference to particular embodiments thereof, a latitude of different modifications, changes and substitutions are proposed in the foregoing description and it will be apparent that in some instances, some features of the invention will be employed without corresponding use of other features, without departing from the scope of the invention as set forth. It should be understood that such substitutions, modifications and variations may be made by those skilled in the art without departing from the spirit or scope of the invention. Accordingly, all modifications and variations are included within the scope of the invention as defined by the following claims. It is noted that in relation to this date, the best method known to the applicant to carry out the aforementioned invention, is that which is clear from the present invention.

Claims (21)

1. CLAIMS 1. A method for the treatment of presbyopia by inducing changes in the physiology of the cornea and in the corneal power that includes: a) inducing the change of the PC (corneal power) when using the contact lens molding and potentiating substance, if it is the case, in the anterior surface radius of the cornea in both eyes; b) to induce the change of the PC when using the contact lens for shaping and potentiating substance, in a single eye as long as the contralateral eye has the mathematical formula that by inheritance produces the far and near vision that the individual requires for their needs of work and according to his age; d) induce the change of the PC when using the contact lens for shaping and potentiating substance, in the anterior surface radius of the cornea; e) perform the PC calculation considering the myopic sphere (myopia) and cylinder (astigmatism) in a certain interval to be able to correct the near vision without significantly reducing distance vision; f) to consider the best axis of astigmatism required for close vision in an individual way, each patient considering each eye separately, the change in the PC with everything and its axis will be the one that the visual memory demands of each individual; g) as the visual memory is unique for each individual, the patient is the one who should guide the expert in the matter to be able to make the necessary change in the PC to be able to have a good vision up close; h) use a shaping contact lens (LCM) which will exert the mechanical force on the anterior surface of the cornea, inducing the change in the required PC. i) once the LCM is placed, add potentiating substances to increase the mechanical strength of the LCM and together produce the permanent transient effect in the PC change in the anterior surface radius of the cornea. 2. The method according to claim 1, wherein the formula for inducing the change in corneal power comprises: i) inducing the change of the PC in the anterior surface radius of the cornea with a value in a myopic interval (sphere) of 0.25 D up to 0.75 D, and myopic astigmatism (cylinder) from 0.25 D up to 0.75 D, according to the age and needs or working distance of the individual to be treated, by inducing the change in the PC in the anterior surface radius of the cornea, greater than 1.00 D in myopia (sphere) and more than 1.00 D in astigmatism (cylinder), increases near vision; but it significantly diminishes vision from afar. ii) induce the change in the PC in the anterior surface radius of the cornea, with the best axis of myopic astigmatism. 3. The method according to claim 1, wherein the recommended interval to correct presbyopia is from approximately 0.100 diopter to 0.999 diopter in myopia as astigmatism, respectively. 4. The method according to claim 2, wherein the best astigmatism axis required for near vision is selected from one of vertical, horizontal or oblique considering each eye separately. The method according to claim 1, wherein the contact lens is one specially designed so that its different base curves in the radii of posterior and anterior curvature, as well as in its diameters of optical zone and peripheral zone, change or they induce the necessary corneal power by dynamically altering the corneal physiology and molding it gradually, uniformly and constantly. The method according to claim 1, wherein the contact lens to be used is one selected from a contact lens molding (LCM), which is a soft or hard lens that will exert mechanical force on the anterior surface of the lens. Cornea to induce the change in the PC required. The method according to claim 6, wherein the selected LCM is the one specially designed to be applied in the dynamic and interactive technique, which its peripheral curvature (CPP) is more curved helping to induce greater encurvamiento. The method according to claim 1, wherein the potentiating substance is a selected one of drops or gel, semi-solid or the like. The method according to claim 8, wherein the drops or gel are applied at intervals of 3 hours or frequently if a more rapid transient permanent molding is desired. The method according to claim 8, wherein the potentiating substances can be combined with anesthetics to avoid the common discomfort of the LCM, enzymes, lubricating drops with different concentrations to lubricate the surface between the cornea and the LCM and improve the comfort for use for as long as necessary to achieve the required corneal stroma molding. The method according to claim 8, wherein the potentiating substances are applied to stabilize or improve or increase the change of the corneal curvature, in the cases of i) after any refractive surgery; ii) without surgery in patients with moderate or low refractive errors; iii) patients who, after 40 years of age, wish to improve their vision closely by presenting symptoms of presbyopia or eyestrain; and iv) in patients under 18 who wish to correct the inherited defect. The method according to claim 1, wherein the treatment is started in the immediate postoperative period after refractive surgery, once the process of epithelial healing is completed, so that the corneal disc is as resistant as possible. and tolerate the contact lens, based on the stromal slip. 13. Kit or ergonomic case containing a reservoir for shaping lens, lens molding, drops or substance in gel potentializers and instructive for its use. 14. Method of dynamic and interactive technique to improve the post-operative mathematical residual based on the change of radius of anterior curvature of the cornea, which consists of altering the normal physiology of the cornea according to claim 1, and together using visual memory and cerebral accommodation to achieve the necessary corneal power and achieve the near vision that is required; where in order to obtain the cerebral accommodation and the required visual memory it is necessary that the cornea is the main organ on which the vision depends and through it be able to make use of the cerebral accommodation and visual memory; which technique is that after the post-operative is measured with the devices currently available, the degree of astigmatism and myopia that a patient has in each eye to determine if. it is in conditions to allow the application of this dynamic and interactive technique; once verified the degree of astigmatism and myopia interact with the patient regarding their near and far vision needs; modifying the corneal curvature with a Contact Lens considering the corneal healing process and the entire cascade of events that occur during the first four weeks; calculate the mathematical formula of your corneal power that includes brain accommodation and visual memory; flattening or flattening the cornea by means of LCM and potentiating substance, depending on whether the patient needs to have good near or far vision; once the LCM has been adapted, proceed to perform all the optometric measurements again in detail to confirm that the LCM is adequate, then the changes that should be induced in the corneal power in the following weeks are calculated. 15. The method according to claim 14, wherein if the patient has not been recently operated on refractive surgery, then a potentiating substance, selected from a drop or semi-solid or solid gel or the like, should be used. 16. The method according to claim 14, wherein the calculations of the changes that should be induced in the corneal power are carried out each week for 8 weeks after having placed the MCL and used the potentiating substance, if the patient is Satisfied with the results obtained, the use of LCM and the potentiating substances is withdrawn until, for some reason, the patient changes his work habits or, due to age, the eye has undergone natural modifications, altering brain accommodation and visual memory. 17. The method according to claim 14, wherein the degree of myopia is in the range of 0.100 D to 0.999 D for astigmatism from 0.100 D to 0.999 D. 18. The method according to claim 14, wherein the The change of anterior curvature in the cornea is of the order of approximately tenths or thousandths of a millimeter. 19. A potentiating substance, comprising a hypotonic or hypertonic agent, together with the MCL during the alteration of the corneal stroma, the curvature of the lamellas can be molded, causing the change of the anterior surface radius. 20. The potentiating substance according to claim 17, which can be combined with anesthetics to avoid the common discomfort of the LCM, lubricating drops with different concentrations to lubricate the surface between the cornea and the LCM and improve the comfort for its use during the time that is necessary to achieve the molding of the corneal stroma. 21. Contact lens molder manufactured from the flatter keratometry or keratometry plus curve or an average of the two, so that based on this corneal curvature the necessary calculations are made to flatten or curl, the anterior surface radius of the cornea and thus correct the refractive defect that is required, besides inducing the necessary corneal power for the correction of presbyopia; the base curve of the LCM is calculated to induce the change in corneal power required for each eye separately, starting with a flatter or more curved diopter depending on the refractive error that is required to correct; the peripheral base curve is calculated, depending on the adaptation of the LCM, calculating approximately 0.5 millimeter radius greater than that of the central zone; the diameter of the central zone in the LCM is approximately 10.0 mm; the power of the LCM is calculated being as close as possible to the refraction required by the patient to perform the most. SUMMARY OF THE INVENTION The present invention refers to an innovative method for the correction of presbyopia or tired eyesight. The method is based on a mechanism for the induction of a mathematical formula in the radius of the anterior surface of the cornea, different from the one inherited by the people and that allows them the near and far vision they require, without the constant dependence on glasses . It consists of producing a compound myopic astigmatism with a vertical axis. The described methods are to change the curvature of the cornea: 1) with contact lens molding® after some refractive surgical technique either Lasik, | Lasek, PRK or any process involving the anterior layers of the cornea or the sclera or any process that alters the refraction of the eyeball; 2) with contact lens molding and potentiating substance® in the form of drops, gel or similar, when the inherited refractive error is moderate -6.00- Diopters or less or when the defect is low -3.00- Diopters or less; 3) when the inherited refractive error does not show dependence on optical correction for far, but with the beginning of the physiological process of presbyopia; 4) with the Dynamic and Interactive® (DI®) technique, by means of which the normal physiology of the cornea is altered and together with the visual memory®, the dynamic changes in the corneal and corporal physiology are induced, according to the needs of work and / or the changes of age that are presented during the natural process of presbyopia. The method allows the physiology of the cornea to be altered in a dynamic way, without producing irreversible changes or anatomo-histological complications in the eye. The corneal power is based on the fine and precise perception of the images produced by the optical-cerebral-motor system (SOCM®). The method uses a computer program, which takes into account the complete formula of AC ® + MV® + SOA® + SOCM®, to individualize corneal power® for both eyes. The technique on which the method is based includes special designs of the contact lens molding and potentiating substances® in the form of drops, gel or similar that help the changes in the collagen fibers, hyaluronic acid, the percentage of corneal hydration and the normal parameters in the anatomy-histology and physiology of the cornea.