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MXPA03000510A - Sales estables de acido o-acetilsalicilico con aminoacidos basicos. - Google Patents

Sales estables de acido o-acetilsalicilico con aminoacidos basicos.

Info

Publication number
MXPA03000510A
MXPA03000510A MXPA03000510A MXPA03000510A MXPA03000510A MX PA03000510 A MXPA03000510 A MX PA03000510A MX PA03000510 A MXPA03000510 A MX PA03000510A MX PA03000510 A MXPA03000510 A MX PA03000510A MX PA03000510 A MXPA03000510 A MX PA03000510A
Authority
MX
Mexico
Prior art keywords
amino acids
acetylsalicyclic
basic amino
stable salts
salts
Prior art date
Application number
MXPA03000510A
Other languages
English (en)
Inventor
Gerhard Franckowiak
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of MXPA03000510A publication Critical patent/MXPA03000510A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

La presente invencion se refiere a sales estables de acido a un procedimiento o-acetilsalicilico con aminoacidos basicos, para su preparacion asi como a su uso como medicamento.
MXPA03000510A 2000-07-18 2001-07-05 Sales estables de acido o-acetilsalicilico con aminoacidos basicos. MXPA03000510A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10034802A DE10034802A1 (de) 2000-07-18 2000-07-18 Stabile Salze von O-Acetylsalicylsäure mit basischen Aminosäuren
PCT/EP2001/007669 WO2002005782A2 (de) 2000-07-18 2001-07-05 Stabile salze von o-acetylsalicylsäure mit basischen aminosäuren

Publications (1)

Publication Number Publication Date
MXPA03000510A true MXPA03000510A (es) 2004-04-20

Family

ID=7649258

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03000510A MXPA03000510A (es) 2000-07-18 2001-07-05 Sales estables de acido o-acetilsalicilico con aminoacidos basicos.

Country Status (34)

Country Link
US (2) US6773724B2 (es)
EP (1) EP1365737B1 (es)
JP (2) JP2004507463A (es)
KR (1) KR100773658B1 (es)
CN (1) CN1205176C (es)
AR (1) AR030305A1 (es)
AT (1) ATE293589T1 (es)
AU (2) AU7847101A (es)
BR (1) BR0112538A (es)
CA (1) CA2416288C (es)
CR (1) CR6888A (es)
CZ (1) CZ300337B6 (es)
DE (2) DE10034802A1 (es)
DK (1) DK1365737T3 (es)
EC (1) ECSP034437A (es)
ES (1) ES2241849T3 (es)
GT (1) GT200100134A (es)
HK (1) HK1061811A1 (es)
HR (1) HRP20030108B1 (es)
HU (1) HUP0302053A3 (es)
IL (2) IL153873A0 (es)
MX (1) MXPA03000510A (es)
MY (1) MY134521A (es)
NO (1) NO20030222L (es)
PE (1) PE20020267A1 (es)
PL (1) PL204593B1 (es)
PT (1) PT1365737E (es)
RS (1) RS50329B (es)
SK (1) SK286162B6 (es)
SV (1) SV2002000557A (es)
TW (1) TWI299729B (es)
UY (1) UY26841A1 (es)
WO (1) WO2002005782A2 (es)
ZA (1) ZA200300469B (es)

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US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
DE10202019A1 (de) * 2002-01-18 2003-07-24 Bayer Ag Stabile Salze von o-Acetylsalicylsäure mit basischen Aminosäuren II
US8142810B2 (en) 2002-05-30 2012-03-27 The Procter & Gamble Company Dietary method for modulating glucose metabolism and associated conditions and increasing longevity
ES2330321T3 (es) * 2003-05-16 2009-12-09 Cephalon France Procedimiento de sintesis de modafinilo.
AU2005277203A1 (en) * 2004-08-20 2006-03-02 Entremed, Inc. Compositions and methods comprising proteinase activated receptor antagonists
US20060166901A1 (en) * 2005-01-03 2006-07-27 Yu Ruey J Compositions comprising O-acetylsalicyl derivatives of aminocarbohydrates and amino acids
DE102005025283A1 (de) 2005-06-02 2006-12-07 Bayer Healthcare Ag Stabiler Wirkstoffkomplex von Salzen der o-Acetylsalicylsäure mit basischen Aminosäuren und Glycin
DE102005049293A1 (de) * 2005-10-15 2007-04-26 Bayer Healthcare Ag Kombinationspräparate von Salzen oder o-Acetylsalicylsäure
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
US20090238763A1 (en) * 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
CA2656858C (en) 2006-07-09 2016-01-19 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of acetylsalicylic acid
KR20210103586A (ko) * 2007-06-04 2021-08-23 테크필즈 인크 매우 높은 피부 및 막 침투율을 가지는 비스테로이드성 소염제(ｎｓａｉａ) 약물전구체 및 이들의 새로운 의약적 용도
DE102008004386A1 (de) 2008-01-14 2009-07-23 Activaero Gmbh Verwendung eines Acetylsalicylsäuresalzes zur Behandlung viraler Infektionen
CN101314029B (zh) * 2008-06-18 2010-12-08 四川省农业科学院实验场 乙酰水杨酸肽及其制备方法
US20100120727A1 (en) * 2008-11-12 2010-05-13 Kyphia Pharmaceuticals, Inc. Eflornithine Prodrugs, Conjugates and Salts, and Methods of Use Thereof
CA3213470A1 (en) 2008-12-04 2010-06-10 Chongxi Yu High penetration compositions and their applications
CN102803199B (zh) * 2009-06-25 2015-04-15 泰特拉有限公司 乙酰水杨酸盐
CN101633624B (zh) * 2009-08-04 2013-05-01 蚌埠丰原医药科技发展有限公司 改进的赖氨匹林的制备方法
FR2965261B1 (fr) 2009-09-30 2012-10-26 Holis Technologies Procede de preparation d'un sel d'acide o-acetylsalicylique d'un acide amine basique et composition obtenue par ce procede
FR2950625B1 (fr) * 2009-09-30 2016-12-02 Holis Tech Procede de preparation d'un sel d'acide o-acetylsalicylique d'un acide amine basique et composition obtenue
FR2973370B1 (fr) * 2011-03-29 2013-05-03 Holis Technologies Procede a faible cout pour la preparation d'un acide o-acetylsalicyclique et d'un acide amine basique
CN102503845A (zh) * 2011-09-28 2012-06-20 广州普星药业有限公司 一种dl-赖氨酸阿司匹林盐的制备方法及其应用
CN104540504A (zh) 2012-01-18 2015-04-22 苏州泰飞尔医药有限公司 治疗肺部疾病的高穿透力前药组合物和医药组合物
CN102976962B (zh) * 2012-11-20 2015-02-04 南京工业大学 L-鸟氨酸阿司匹林复盐及其制备方法和应用
FR3021654B1 (fr) * 2014-05-28 2016-06-24 Unither Pharmaceuticals Procede de preparation d'un sel d'acide acetylsalicylique et d'un acide amine basique
US10882811B2 (en) * 2016-12-23 2021-01-05 Aspiair Gmbh Synthesis of lysine acetylsalicylate glycine particles
CA3064012A1 (en) 2017-05-30 2018-12-06 Rhoshan Pharmaceuticals, Inc. In-vial deposition of a stable, sterile and crystalline o-acetyl salicylic acid (aspirin)
JPWO2019026992A1 (ja) * 2017-08-03 2020-06-18 参天製薬株式会社 クロルヘキシジンを含有する医薬組成物
CN113105326A (zh) * 2021-03-24 2021-07-13 海南卓华制药有限公司 赖氨匹林的制备方法及应用
CN114478287A (zh) * 2021-12-31 2022-05-13 蚌埠丰原医药科技发展有限公司 一种赖氨匹林晶型及制备方法和应用
JP2025501974A (ja) 2022-01-05 2025-01-24 アスピエアー ゲーエムベーハー アセチルサリチル酸リジン・グリシン粒子の改良された合成

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FR2115060A1 (en) * 1970-11-26 1972-07-07 Metabio Freeze-dried acetylsalicylates of lysine and arginine - easily prepd derivs of aspirin
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Also Published As

Publication number Publication date
DE50105985D1 (de) 2005-05-25
GT200100134A (es) 2002-03-22
IL153873A0 (en) 2003-07-31
HUP0302053A3 (en) 2010-03-29
DK1365737T3 (da) 2005-07-11
NO20030222D0 (no) 2003-01-16
AU7847101A (en) 2002-01-30
HUP0302053A2 (hu) 2003-09-29
HRP20030108B1 (en) 2006-12-31
IL153873A (en) 2009-05-04
US7449198B2 (en) 2008-11-11
HRP20030108A2 (en) 2005-02-28
CN1468209A (zh) 2004-01-14
CZ300337B6 (cs) 2009-04-22
ECSP034437A (es) 2003-03-31
ZA200300469B (en) 2004-06-21
KR100773658B1 (ko) 2007-11-05
ATE293589T1 (de) 2005-05-15
US20020091108A1 (en) 2002-07-11
KR20030019586A (ko) 2003-03-06
CA2416288A1 (en) 2003-01-15
US20050009791A1 (en) 2005-01-13
SK672003A3 (en) 2003-06-03
JP2004507463A (ja) 2004-03-11
CN1205176C (zh) 2005-06-08
HK1061811A1 (en) 2004-10-08
MY134521A (en) 2007-12-31
PL365648A1 (en) 2005-01-10
WO2002005782A2 (de) 2002-01-24
SK286162B6 (sk) 2008-04-07
ES2241849T3 (es) 2005-11-01
AR030305A1 (es) 2003-08-20
AU2001278471B2 (en) 2004-07-22
PL204593B1 (pl) 2010-01-29
NO20030222L (no) 2003-01-16
US6773724B2 (en) 2004-08-10
TWI299729B (en) 2008-08-11
CR6888A (es) 2004-10-28
EP1365737B1 (de) 2005-04-20
YU2003A (sh) 2006-08-17
SV2002000557A (es) 2002-10-24
CZ2003164A3 (cs) 2003-04-16
RS50329B (sr) 2009-09-08
UY26841A1 (es) 2002-02-28
DE10034802A1 (de) 2002-01-31
PE20020267A1 (es) 2002-06-08
BR0112538A (pt) 2003-09-09
JP2012131824A (ja) 2012-07-12
PT1365737E (pt) 2005-08-31
CA2416288C (en) 2009-12-22
WO2002005782A3 (de) 2003-10-02
EP1365737A2 (de) 2003-12-03

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