MXPA02005101A - Derivados de indol canabimimeticos. - Google Patents

Derivados de indol canabimimeticos.

Info

Publication number: MXPA02005101A
Authority: MX; Mexico
Prior art keywords: indole derivatives; cannabimimetic; cannabimimetic indole; derivatives; indole
Prior art date: 1999-10-18

Application number

MXPA02005101A

Other languages

English (en)

Inventor

Alexandros Makriyannis

Original Assignee

Alexipharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-18

Filing date

2000-10-18

Publication date

2003-09-25

2000-10-18 Application filed by Alexipharma Inc filed Critical Alexipharma Inc

2003-09-25 Publication of MXPA02005101A publication Critical patent/MXPA02005101A/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Virology (AREA)
Ophthalmology & Optometry (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Oncology (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Hematology (AREA)
Obesity (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

MXPA02005101A 1999-10-18 2000-10-18 Derivados de indol canabimimeticos. MXPA02005101A (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US15999799P	1999-10-18	1999-10-18
PCT/US2000/028832 WO2001028557A1 (en)	1999-10-18	2000-10-18	Cannabimimetic indole derivatives

Publications (1)

Publication Number	Publication Date
MXPA02005101A true MXPA02005101A (es)	2003-09-25

Family

ID=22575037

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MXPA02005101A MXPA02005101A (es)	1999-10-18	2000-10-18	Derivados de indol canabimimeticos.

Country Status (8)

Country	Link
EP (1)	EP1223929B1 (es)
JP (1)	JP2003512326A (es)
AU (1)	AU1095101A (es)
CA (1)	CA2387138A1 (es)
DE (1)	DE60030303T2 (es)
MX (1)	MXPA02005101A (es)
WO (1)	WO2001028557A1 (es)
ZA (1)	ZA200203911B (es)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1075470B1 (en)	1998-05-04	2003-08-13	The University Of Connecticut	Novel analgesic and immunomodulatory cannabinoids
US7589220B2 (en)	1998-06-09	2009-09-15	University Of Connecticut	Inhibitors of the anandamide transporter
US7276613B1 (en)	1998-11-24	2007-10-02	University Of Connecticut	Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en)	1998-11-24	2007-01-09	University Of Connecticut	Cannabimimetic lipid amides as useful medications
US7119108B1 (en)	1999-10-18	2006-10-10	University Of Connecticut	Pyrazole derivatives as cannabinoid receptor antagonists
US7393842B2 (en)	2001-08-31	2008-07-01	University Of Connecticut	Pyrazole analogs acting on cannabinoid receptors
WO2001028329A1 (en)	1999-10-18	2001-04-26	University Of Connecticut	Peripheral cannabinoid receptor (cb2) selective ligands
US6943266B1 (en)	1999-10-18	2005-09-13	University Of Connecticut	Bicyclic cannabinoid agonists for the cannabinoid receptor
US6900236B1 (en)	1999-10-18	2005-05-31	University Of Connecticut	Cannabimimetic indole derivatives
FR2816938B1 (fr)	2000-11-22	2003-01-03	Sanofi Synthelabo	Derives de 3-aroylindole, leur procede de preparation et les compositions pharmaceutiques en contenant
US7329651B2 (en)	2001-01-26	2008-02-12	University Of Connecticut	Cannabimimetic ligands
DE60237431D1 (de)	2001-01-29	2010-10-07	Univ Connecticut	Rezeptor-selektive cannabimimetische aminoalkylindole
US7067539B2 (en) *	2001-02-08	2006-06-27	Schering Corporation	Cannabinoid receptor ligands
US7507767B2 (en)	2001-02-08	2009-03-24	Schering Corporation	Cannabinoid receptor ligands
JP4312594B2 (ja)	2001-07-13	2009-08-12	ユニバーシティオブコネチカット	新規な二環式及び三環式カンナビノイド
WO2003007887A2 (en)	2001-07-20	2003-01-30	Merck & Co., Inc.	Substituted imidazoles as cannabinoid receptor modulators
TWI317634B (en)	2001-12-13	2009-12-01	Nat Health Research Institutes	Aroyl indoles compounds
US7632955B2 (en)	2001-12-13	2009-12-15	National Health Research Institutes	Indole compounds
US7528165B2 (en)	2001-12-13	2009-05-05	National Health Research Institutes	Indole compounds
WO2003061699A1 (fr) *	2001-12-27	2003-07-31	Japan Tobacco, Inc.	Remedes pour affections allergiques
EP1487436A4 (en)	2002-03-08	2009-06-03	Signal Pharm Inc	POLYTHERAPY FOR TREATING, PREVENTING OR MANAGING PROLIFERATIVE DISORDERS AND CANCERS
FR2839718B1 (fr)	2002-05-17	2004-06-25	Sanofi Synthelabo	Derives d'indole, leur procede de preparation et les compositions pharmaceutiques en contenant
BR0313041A (pt)	2002-07-29	2005-06-21	Hoffmann La Roche	Compostos; composições farmacêuticas; método para o tratamento e/ou profilaxia de doenças que estão associadas à modulação dos receptores de cb1; e uso de compostos
US7091216B2 (en)	2002-08-02	2006-08-15	Merck & Co., Inc.	Substituted furo[2,3-b]pyridine derivatives
US7183313B2 (en)	2002-08-23	2007-02-27	University Of Connecticut	Keto cannabinoids with therapeutic indications
US7129239B2 (en)	2002-10-28	2006-10-31	Pfizer Inc.	Purine compounds and uses thereof
US7247628B2 (en)	2002-12-12	2007-07-24	Pfizer, Inc.	Cannabinoid receptor ligands and uses thereof
US7329658B2 (en)	2003-02-06	2008-02-12	Pfizer Inc	Cannabinoid receptor ligands and uses thereof
US7176210B2 (en)	2003-02-10	2007-02-13	Pfizer Inc.	Cannabinoid receptor ligands and uses thereof
TW200505902A (en) *	2003-03-20	2005-02-16	Schering Corp	Cannabinoid receptor ligands
US7141669B2 (en)	2003-04-23	2006-11-28	Pfizer Inc.	Cannabiniod receptor ligands and uses thereof
US7268133B2 (en)	2003-04-23	2007-09-11	Pfizer, Inc. Patent Department	Cannabinoid receptor ligands and uses thereof
US7145012B2 (en)	2003-04-23	2006-12-05	Pfizer Inc.	Cannabinoid receptor ligands and uses thereof
US7232823B2 (en)	2003-06-09	2007-06-19	Pfizer, Inc.	Cannabinoid receptor ligands and uses thereof
CA2592378A1 (en)	2004-12-21	2006-06-29	Abbott Laboratories	3-cycloalkylcarbonyl indoles as cannabinoid receptor ligands
US7456289B2 (en)	2004-12-31	2008-11-25	National Health Research Institutes	Anti-tumor compounds
WO2008051197A2 (en) *	2005-09-20	2008-05-02	Mayo Foundation For Medical Education And Research	Small-molecule botulinum toxin inhibitors
NZ570014A (en)	2006-02-03	2011-04-29	Bionomics Ltd	Substituted benzofurans, benzothiophenes, benzoselenophenes and indoles and their use as tubulin polymerisation inhibitors
MX2008015214A (es)	2006-05-31	2008-12-12	Abbott Lab	Compuestos como ligandos de receptor canabinoide y sus usos.
US8841334B2 (en)	2006-05-31	2014-09-23	Abbvie Inc.	Compounds as cannabinoid receptor ligands and uses thereof
EP2142522A1 (en)	2007-03-28	2010-01-13	Abbott Laboratories	1, 3-thiazol-2 (3h) -ylidene compounds as cannabinoid receptor ligands
US7872033B2 (en)	2007-04-17	2011-01-18	Abbott Laboratories	Compounds as cannabinoid receptor ligands
JP2010527929A (ja)	2007-05-18	2010-08-19	アボット・ラボラトリーズ	カンナビノイド受容体リガンドとしての新規な化合物
US7943653B2 (en) *	2007-08-13	2011-05-17	Janssen Pharmaceutica N.V.	Substituted 5-vinylphenyl-1-phenyl-pyrazole cannabinoid modulators
US9193713B2 (en)	2007-10-12	2015-11-24	Abbvie Inc.	Compounds as cannabinoid receptor ligands
IE20070928A1 (en) *	2007-12-21	2009-09-30	Giuliani Int Ltd	Multi target ligands
US8846730B2 (en)	2008-09-08	2014-09-30	Abbvie Inc.	Compounds as cannabinoid receptor ligands
UY32125A (es)	2008-09-16	2010-04-30	Abbott Lab	Compuestos novedosos como ligandos de receptores de canabinoides
PA8854001A1 (es)	2008-12-16	2010-07-27	Abbott Lab	Compuestos novedosos como ligandos de receptores de canabinoides
EP4108665A1 (en) *	2016-06-23	2022-12-28	F. Hoffmann-La Roche AG	[1,2,3]triazolo[4,5-d]pyrimidine derivatives with affinity for the type-2 cannabinoid receptor
WO2025007055A1 (en) *	2023-06-29	2025-01-02	Volastra Therapeutics, Inc.	Aryl indol-3-yl ketone and aryl indazol-3-yl ketone inhibitors of kif18a

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2665444B1 (fr) *	1990-08-06	1992-11-27	Sanofi Sa	Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
FR2735774B1 (fr) *	1995-06-21	1997-09-12	Sanofi Sa	Utilisation de composes agonistes du recepteur cb2 humain pour la preparation de medicaments immunomodulateurs, nouveaux composes agonistes du recepteur cb2 et les compositions pharmaceutiques les contenant
DE19706903A1 (de) *	1997-02-21	1998-08-27	Bayer Ag	Verwendung von bekannten Agonisten des zentralen Cannabinoid-Rezeptors CB 1

2000
- 2000-10-18 AU AU10951/01A patent/AU1095101A/en not_active Abandoned
- 2000-10-18 CA CA002387138A patent/CA2387138A1/en not_active Abandoned
- 2000-10-18 WO PCT/US2000/028832 patent/WO2001028557A1/en active IP Right Grant
- 2000-10-18 JP JP2001531387A patent/JP2003512326A/ja active Pending
- 2000-10-18 DE DE60030303T patent/DE60030303T2/de not_active Expired - Fee Related
- 2000-10-18 EP EP00972266A patent/EP1223929B1/en not_active Expired - Lifetime
- 2000-10-18 MX MXPA02005101A patent/MXPA02005101A/es active IP Right Grant
2002
- 2002-05-16 ZA ZA200203911A patent/ZA200203911B/en unknown

Also Published As

Publication number	Publication date
DE60030303T2 (de)	2007-10-11
DE60030303D1 (de)	2006-10-05
EP1223929B1 (en)	2006-08-23
WO2001028557B1 (en)	2001-06-07
EP1223929A1 (en)	2002-07-24
AU1095101A (en)	2001-04-30
ZA200203911B (en)	2003-08-25
CA2387138A1 (en)	2001-04-26
JP2003512326A (ja)	2003-04-02
WO2001028557A1 (en)	2001-04-26
EP1223929A4 (en)	2002-12-04

Publication	Publication Date	Title
MXPA02005101A (es)	2003-09-25	Derivados de indol canabimimeticos.
ZA200000894B (en)	2000-08-24	4-Phenyl-pyridine derivatives.
ZA200201055B (en)	2003-07-30	Amino-triazolopyridine derivatives.
ZA200202544B (en)	2003-09-23	Benzodiazepine derivatives.
MXPA03000939A (es)	2003-06-24	Derivados de imidazol.
ZA200109595B (en)	2003-05-28	13-methyl-erythromycin derivatives.
ZA988078B (en)	2000-03-22	Substituted oxindole derivatives.
MXPA01013362A (es)	2003-09-04	Anticuerpos de humano, anti-alfavbeta3 recombinantes, °cidos nucleicos que codifican a los mismos y metodos de uso.
ZA99254B (en)	1999-07-16	Benzosulfone derivatives.
ZA200200477B (en)	2003-06-25	2-pyrazolin-5-ones.
ZA200203003B (en)	2003-09-23	N-substituted carbamoyloxyalkyl-azolium derivatives.
ZA200202537B (en)	2003-09-23	Pour-on-formulations.
ZA200203762B (en)	2004-01-28	4-pyridinyl-IN-acyl-L-phenylalanines.
MXPA01012041A (es)	2003-09-04	Derivados de indol.
ZA991550B (en)	1999-08-26	Cyclohexanediole derivatives.
ZA200205482B (en)	2003-12-31	Aminosulfonylbiphenyl derivatives.
ZA200206151B (en)	2003-11-03	Substituted amionomethyl-phenyl-cyclohexane derivatives.
MXPA03002737A (es)	2004-01-26	Derivados sustituidos de 1-aminobutan-3-ol.
ZA200108913B (en)	2003-03-26	Imidazodiazepine derivative.
MXPA00011504A (es)	2003-12-12	Derivados heterociclicos sustituidos.
IL150336A0 (en)	2002-12-01	Novel indole derivatives
HUP0202479A3 (en)	2003-12-29	Indole derivatives
ZA200201276B (en)	2003-07-30	3-Amino-2-phenyl-propane derivatives.
ZA200206150B (en)	2003-11-03	Aminomethyl-phenyl-cyclohexanone derivatives.
ZA200205301B (en)	2003-10-02	New imidazole derivatives.

Legal Events

Date	Code	Title	Description
2006-09-14	FG	Grant or registration