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MX9706107A - Methods and uses for apoptin. - Google Patents

Methods and uses for apoptin.

Info

Publication number
MX9706107A
MX9706107A MX9706107A MX9706107A MX9706107A MX 9706107 A MX9706107 A MX 9706107A MX 9706107 A MX9706107 A MX 9706107A MX 9706107 A MX9706107 A MX 9706107A MX 9706107 A MX9706107 A MX 9706107A
Authority
MX
Mexico
Prior art keywords
apoptin
apoptosis
normal cells
tumor
cells
Prior art date
Application number
MX9706107A
Other languages
Spanish (es)
Inventor
Vicente Solana Gomez
Original Assignee
Vicente Solana Gomez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8292378&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9706107(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vicente Solana Gomez filed Critical Vicente Solana Gomez
Publication of MX9706107A publication Critical patent/MX9706107A/en

Links

Classifications

    • E—FIXED CONSTRUCTIONS
    • E04—BUILDING
    • E04B—GENERAL BUILDING CONSTRUCTIONS; WALLS, e.g. PARTITIONS; ROOFS; FLOORS; CEILINGS; INSULATION OR OTHER PROTECTION OF BUILDINGS
    • E04B5/00—Floors; Floor construction with regard to insulation; Connections specially adapted therefor
    • E04B5/16—Load-carrying floor structures wholly or partly cast or similarly formed in situ
    • E04B5/17—Floor structures partly formed in situ
    • E04B5/23—Floor structures partly formed in situ with stiffening ribs or other beam-like formations wholly or partly prefabricated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B28—WORKING CEMENT, CLAY, OR STONE
    • B28B—SHAPING CLAY OR OTHER CERAMIC COMPOSITIONS; SHAPING SLAG; SHAPING MIXTURES CONTAINING CEMENTITIOUS MATERIAL, e.g. PLASTER
    • B28B7/00—Moulds; Cores; Mandrels
    • B28B7/0064—Moulds characterised by special surfaces for producing a desired surface of a moulded article, e.g. profiled or polished moulding surfaces
    • B28B7/0085—Moulds characterised by special surfaces for producing a desired surface of a moulded article, e.g. profiled or polished moulding surfaces with surfaces for moulding chamfers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B28—WORKING CEMENT, CLAY, OR STONE
    • B28B—SHAPING CLAY OR OTHER CERAMIC COMPOSITIONS; SHAPING SLAG; SHAPING MIXTURES CONTAINING CEMENTITIOUS MATERIAL, e.g. PLASTER
    • B28B7/00—Moulds; Cores; Mandrels
    • B28B7/10—Moulds with means incorporated therein, or carried thereby, for ejecting or detaching the moulded article
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B28—WORKING CEMENT, CLAY, OR STONE
    • B28B—SHAPING CLAY OR OTHER CERAMIC COMPOSITIONS; SHAPING SLAG; SHAPING MIXTURES CONTAINING CEMENTITIOUS MATERIAL, e.g. PLASTER
    • B28B7/00—Moulds; Cores; Mandrels
    • B28B7/36—Linings or coatings, e.g. removable, absorbent linings, permanent anti-stick coatings; Linings becoming a non-permanent layer of the moulded article
    • E—FIXED CONSTRUCTIONS
    • E04—BUILDING
    • E04B—GENERAL BUILDING CONSTRUCTIONS; WALLS, e.g. PARTITIONS; ROOFS; FLOORS; CEILINGS; INSULATION OR OTHER PROTECTION OF BUILDINGS
    • E04B5/00—Floors; Floor construction with regard to insulation; Connections specially adapted therefor
    • E04B5/02—Load-carrying floor structures formed substantially of prefabricated units
    • E04B5/04—Load-carrying floor structures formed substantially of prefabricated units with beams or slabs of concrete or other stone-like material, e.g. asbestos cement

Landscapes

  • Engineering & Computer Science (AREA)
  • Architecture (AREA)
  • Manufacturing & Machinery (AREA)
  • Chemical & Material Sciences (AREA)
  • Ceramic Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Civil Engineering (AREA)
  • Electromagnetism (AREA)
  • Physics & Mathematics (AREA)
  • Structural Engineering (AREA)
  • Manufacturing Of Tubular Articles Or Embedded Moulded Articles (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Moulds, Cores, Or Mandrels (AREA)
  • Rod-Shaped Construction Members (AREA)
  • Forms Removed On Construction Sites Or Auxiliary Members Thereof (AREA)
  • Building Environments (AREA)

Abstract

This invention describes that apoptin fails to induce apoptosis in human normal cells. Besides, the invention describes that when normal cells are transformed, they become susceptible to the apoptin-induced apoptosis. The invention describes that apoptin induces in various human tumor cells a p53-distinct type of apoptosis, and cannot be blocked by a variety of apoptosis-inhibiting agents. The invention comprises an anti-tumor agent, which specifically kill tumor and not normal cells. It further provides the induction of cell death by means of gene therapy. Apoptin can induce apoptosis in non-human animal tumor cells. The invention also provides that in normal cells apoptin was found predominantly in the cytoplasm, while in tumor cells it was located in the nucleus. Besides, the invention comprises a diagnostic test for the determination of cell-transforming activity.
MX9706107A 1995-12-01 1996-11-27 Methods and uses for apoptin. MX9706107A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES9502383 1995-12-01
PCT/ES1996/000229 WO1997020666A1 (en) 1995-12-01 1996-11-27 Mold for prefabricated concrete panels

Publications (1)

Publication Number Publication Date
MX9706107A true MX9706107A (en) 1997-11-29

Family

ID=8292378

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9706107A MX9706107A (en) 1995-12-01 1996-11-27 Methods and uses for apoptin.

Country Status (5)

Country Link
EP (1) EP0818287B1 (en)
DE (1) DE69624226T2 (en)
ES (1) ES2179955T3 (en)
MX (1) MX9706107A (en)
WO (1) WO1997020666A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000077317A1 (en) * 1999-06-09 2000-12-21 Brentmuir Developments (1993) Limited Concrete panel construction system
US6698150B1 (en) 1998-06-09 2004-03-02 Brentmuir Developments (1993) Limited Concrete panel construction system
US7828544B2 (en) 2004-11-26 2010-11-09 Brentmuir Developments (1993) Limited Concrete panel construction system and method of making panels
US9399867B2 (en) 2009-04-07 2016-07-26 Millwick Acquisition Corp. Concrete panel corner connection
NL2004864C2 (en) * 2010-06-09 2011-12-13 Infra & B V Moulds and methods for forming prefab concrete floor elements and prefab elements.
WO2016183639A1 (en) 2015-05-21 2016-11-24 Lifting Point Pre-Form Pty Limited A module for a structure
CN108772944A (en) * 2018-05-07 2018-11-09 安徽砼宇特构科技有限公司 Convenient fixed mounting formula precast concrete case
CN109176862B (en) * 2018-11-09 2023-09-29 新疆博壹市政工程有限责任公司 Manufacturing equipment structure and manufacturing method of ribbed prestressed prefabricated bottom plate
CN114482375B (en) * 2022-02-22 2023-07-28 杭州江润科技有限公司 Construction method of integral joint type reinforced concrete superimposed sheet

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR886179A (en) * 1942-08-29 1943-10-07 Demoulding method and device
BE756509A (en) * 1969-09-23 1971-03-01 Haller Hans FLOOR CONSISTING OF PREFABRICATED ELEMENTS JUXTAPOSED AND MOLDED, AND PROCESS FOR THEIR MANUFACTURING
NL148528B (en) * 1973-02-27 1976-02-16 Kalkman Maschf En Handelsonder DEVICE FOR THE MANUFACTURE OF A TILE WITH A CIRCULAR FACETED EDGE.
DE3109108A1 (en) * 1981-03-11 1982-09-23 Karl Lösch KG, 6722 Lingenfeld Moulded concrete slab with chamfer
JPH02301404A (en) * 1989-05-16 1990-12-13 Okagaki Kogyo Kk Descaling cleaning of steel concrete frame
ES2076856B1 (en) * 1993-03-03 1998-11-01 Ruiz Miguel Camarero CONSTRUCTION SYSTEM OF PREFABRICATED SEAT PLATES.
DE4333080A1 (en) * 1993-09-29 1995-03-30 Ebawe Maschinenbau Gmbh Mould for producing panel-like or slab-like precast concrete units

Also Published As

Publication number Publication date
EP0818287B1 (en) 2002-10-09
DE69624226D1 (en) 2002-11-14
DE69624226T2 (en) 2003-10-30
EP0818287A1 (en) 1998-01-14
ES2179955T3 (en) 2003-02-01
WO1997020666A1 (en) 1997-06-12

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