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MX9700820A - Nuevos derivados del imidazol, su procedimiento de preparacion, los novedosos intermediarios obtenidos, su aplicacion como medicamentos y las composiciones farmaceuticas que los incluyen. - Google Patents

Nuevos derivados del imidazol, su procedimiento de preparacion, los novedosos intermediarios obtenidos, su aplicacion como medicamentos y las composiciones farmaceuticas que los incluyen.

Info

Publication number
MX9700820A
MX9700820A MX9700820A MX9700820A MX9700820A MX 9700820 A MX9700820 A MX 9700820A MX 9700820 A MX9700820 A MX 9700820A MX 9700820 A MX9700820 A MX 9700820A MX 9700820 A MX9700820 A MX 9700820A
Authority
MX
Mexico
Prior art keywords
same
novel
pharmaceutical compositions
compositions containing
imidazole derivatives
Prior art date
Application number
MX9700820A
Other languages
English (en)
Inventor
Bertrand Heckmann
Jean-Paul Vevert
Jidong Zhang
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of MX9700820A publication Critical patent/MX9700820A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se describen los nuevos productos de la formula (I), en donde R1 es hidrogeno o, hidroxilo, alcoxi, formilo, dioxol, arilo, arilcarbonilo, ariltio, alquilcarbonilo, R1 y R3 son halogeno, mercapto, acilo, carboxilo, nitro, ciano, amino, carbamoilo, R4 -OR4 y R4 son hidrogeno, alquilo, alquenilo, alquinilo, acilo, amino, -(CH2)m1 S(0)m2-X-R10; en donde ml = 0-4, m2 = 0-2, X es un enlace sencillo o -NH-, -NH-CO, -NH-CO-NH- y R10 es alquilo, alquenilo o arilo e Y es arilo opcionalmente substituido, dichos productos son obtenidos en todas las formas isoméricas, sus sales y su nueva utilizacion como medicamentos.
MX9700820A 1994-08-02 1995-08-01 Nuevos derivados del imidazol, su procedimiento de preparacion, los novedosos intermediarios obtenidos, su aplicacion como medicamentos y las composiciones farmaceuticas que los incluyen. MX9700820A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9409565A FR2723369B1 (fr) 1994-08-02 1994-08-02 Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
PCT/FR1995/001033 WO1996004275A1 (fr) 1994-08-02 1995-08-01 Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
MX9700820A true MX9700820A (es) 1997-05-31

Family

ID=9465985

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9700820A MX9700820A (es) 1994-08-02 1995-08-01 Nuevos derivados del imidazol, su procedimiento de preparacion, los novedosos intermediarios obtenidos, su aplicacion como medicamentos y las composiciones farmaceuticas que los incluyen.

Country Status (18)

Country Link
US (1) US5856509A (es)
EP (1) EP0804435B1 (es)
JP (1) JP3950475B2 (es)
CN (1) CN1083838C (es)
AT (1) ATE261442T1 (es)
AU (1) AU703078B2 (es)
BR (1) BR9508482A (es)
CA (1) CA2196219A1 (es)
DE (1) DE69532684T2 (es)
ES (1) ES2214504T3 (es)
FI (1) FI970423A (es)
FR (1) FR2723369B1 (es)
HU (1) HU221463B (es)
IL (1) IL114663A0 (es)
MX (1) MX9700820A (es)
RU (1) RU2171257C2 (es)
WO (1) WO1996004275A1 (es)
ZA (1) ZA956450B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2740774B1 (fr) * 1995-11-08 1997-12-19 Roussel Uclaf Nouveaux derives d'imidazole n-benzyldioxole, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
EP0990439A4 (en) * 1997-05-22 2004-01-28 Kyowa Hakko Kogyo Kk BISARYL COMPOUNDS AND ANTICIPATING MEDICAMENTS CONTAINING THEM
EP2095819A1 (en) * 2008-02-28 2009-09-02 Maastricht University N-benzyl imidazole derivatives and their use as aldosterone synthase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2862340D1 (en) * 1978-02-01 1983-11-24 Wellcome Found Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof
JPH07509465A (ja) * 1992-07-17 1995-10-19 スミスクライン・ビーチャム・コーポレイション エンドセリン受容体アンタゴニスト

Also Published As

Publication number Publication date
DE69532684D1 (de) 2004-04-22
FR2723369A1 (fr) 1996-02-09
DE69532684T2 (de) 2004-07-29
IL114663A0 (en) 1995-11-27
BR9508482A (pt) 1999-06-01
ATE261442T1 (de) 2004-03-15
CA2196219A1 (fr) 1996-02-15
FI970423A (fi) 1997-04-01
WO1996004275A1 (fr) 1996-02-15
HUT76838A (en) 1997-11-28
FI970423A0 (fi) 1997-01-31
EP0804435A1 (fr) 1997-11-05
AU703078B2 (en) 1999-03-11
ZA956450B (en) 1996-08-05
CN1159805A (zh) 1997-09-17
JP3950475B2 (ja) 2007-08-01
RU2171257C2 (ru) 2001-07-27
CN1083838C (zh) 2002-05-01
EP0804435B1 (fr) 2004-03-10
FR2723369B1 (fr) 1996-09-13
AU3117895A (en) 1996-03-04
JPH10503512A (ja) 1998-03-31
HU221463B (en) 2002-10-28
US5856509A (en) 1999-01-05
ES2214504T3 (es) 2004-09-16

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