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MX9604808A - Bicyclic thiophene derivatives and use as gonadotropin releasing hormone antagonists. - Google Patents

Bicyclic thiophene derivatives and use as gonadotropin releasing hormone antagonists.

Info

Publication number
MX9604808A
MX9604808A MX9604808A MX9604808A MX9604808A MX 9604808 A MX9604808 A MX 9604808A MX 9604808 A MX9604808 A MX 9604808A MX 9604808 A MX9604808 A MX 9604808A MX 9604808 A MX9604808 A MX 9604808A
Authority
MX
Mexico
Prior art keywords
agent
cancer
releasing hormone
homo
hetero
Prior art date
Application number
MX9604808A
Other languages
Spanish (es)
Inventor
Shuichi Furuya
Nobuo Choh
Koichi Kato
Shuji Hinuma
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority claimed from PCT/JP1995/000728 external-priority patent/WO1995028405A1/en
Publication of MX9604808A publication Critical patent/MX9604808A/en

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Abstract

A gonadotropin-releasing hormone antagonistic composition, which comprises an optionally substituted condensed-bicyclic compound consisting of a homo or hetero 5 to 7 membered ring and a homo or hetero 5 to 7 membered ring such as compounds of formulae (I) or (II) is effective as a propylactic or therapeutic agent for the prevention or treatment of several hormone dependent diseases, for example, a sex hormone dependent cancer (e.g. prostatic cancer, cancer of the uterine cervix, breast cancer, pituitary adenoma), benign prostatic hypertrophy, myoma of the uterus, endometriosis, precocious puberty, amenorrhea, premenstrual syndrome, polycystic ovary syndrome and acne vulgaris; is effective as a fertility controlling agent in both sexes (e.g. a pregnancy controlling agent and a menstrual cycle controlling agent); can be used as a contraceptive of male or female, as an ovulation-inducing agent of female; can be used as an infertility treating agent by using a rebound effect owing to a stoppage of administration thereof; is useful as modulating estrous cycles in animals in the field of animal husbandry, as an agent for improving the quality of edible meat or promoting the growth of animals; is useful as an agent of spawning promotion in fish.
MX9604808A 1994-08-19 1995-04-14 Bicyclic thiophene derivatives and use as gonadotropin releasing hormone antagonists. MX9604808A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP19554194 1994-08-19
JP27101094 1994-11-04
JP2071795 1995-02-08
JP4015195 1995-02-28
PCT/JP1995/000728 WO1995028405A1 (en) 1994-04-19 1995-04-14 Bicyclic thiophene derivatives and use as gonadotropin releasing hormone antagonists

Publications (1)

Publication Number Publication Date
MX9604808A true MX9604808A (en) 1998-02-28

Family

ID=39164989

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9604808A MX9604808A (en) 1994-08-19 1995-04-14 Bicyclic thiophene derivatives and use as gonadotropin releasing hormone antagonists.

Country Status (1)

Country Link
MX (1) MX9604808A (en)

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