MX9405111A - Nuevos derivados de (1-fenil-1-heterociclil)metanol y(1-fenil-1-heterociclil-metilamina). - Google Patents
Nuevos derivados de (1-fenil-1-heterociclil)metanol y(1-fenil-1-heterociclil-metilamina).Info
- Publication number
- MX9405111A MX9405111A MX9405111A MX9405111A MX9405111A MX 9405111 A MX9405111 A MX 9405111A MX 9405111 A MX9405111 A MX 9405111A MX 9405111 A MX9405111 A MX 9405111A MX 9405111 A MX9405111 A MX 9405111A
- Authority
- MX
- Mexico
- Prior art keywords
- lower alkyl
- phenyl
- heterociclil
- compounds
- acyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
La presente invención se relaciona con compuestos heterocíclicos novedososque tienen la fórmula general (1) en la que: X es O, S o Se; R1 es H,alquilo inferior, alcoxi inferior-alquilo inferior, arilalquilo inferior oCF3; R2 es H, alquilo inferior, alcoxi inferior-alquilo inferior,arilalquilo inferior o CF3; W es O, S, NH o N-alquilo inferior; R3 es H,alquilo inferior o acilo inferior; Ar es fenilo, furilo, tienilo, naftilo,piridilo o pirrolilo opcionalmente sustituido por R6; R6 son uno o másgrupos seleccionados de alquilo inferior, acilo inferior, halógeno, alcoxiinferior, CF3, OH, NO2 o NR4R5, en el que R4 y R5 son independientementeH, alquilo inferior o acilo inferior; los isómeros geométricos y ópticos yracematos de los mismos, cuando existan tales isómeros, así como las salesde adición de ácido farmacéuticamente aceptables de los mismos y lossolvatos de los mismos que tengan actividad terapéutica, con procesosintermediarios para su preparación, con formulaciones farmacéuticas quecontienen tales compuestos y con el uso médico de tales compuestos.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9302334A SE9302334D0 (sv) | 1993-07-06 | 1993-07-06 | New compounds |
| US08/379,469 US5712299A (en) | 1993-07-03 | 1994-07-05 | (1-phenyl-1-heterocyclyl)methanol and (1-phenyl-1-heterocyclyl methylamine derivatives |
| US45663795A | 1995-06-02 | 1995-06-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9405111A true MX9405111A (es) | 1995-01-31 |
Family
ID=27355726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9405111A MX9405111A (es) | 1993-07-06 | 1994-07-05 | Nuevos derivados de (1-fenil-1-heterociclil)metanol y(1-fenil-1-heterociclil-metilamina). |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5712299A (es) |
| EP (1) | EP0707574A1 (es) |
| JP (1) | JPH08512314A (es) |
| CN (1) | CN1047169C (es) |
| AU (1) | AU691821B2 (es) |
| BR (1) | BR9406925A (es) |
| CA (1) | CA2164960A1 (es) |
| CZ (1) | CZ4296A3 (es) |
| FI (1) | FI960078A0 (es) |
| HU (1) | HUT74671A (es) |
| IL (1) | IL110158A (es) |
| MX (1) | MX9405111A (es) |
| NO (1) | NO305953B1 (es) |
| NZ (1) | NZ268691A (es) |
| PL (1) | PL179015B1 (es) |
| SG (1) | SG48081A1 (es) |
| SK (1) | SK160095A3 (es) |
| WO (1) | WO1995001968A1 (es) |
| ZA (1) | ZA944647B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995029898A1 (en) * | 1994-05-02 | 1995-11-09 | Zeneca Limited | Herbicidal hydroxybenzyl-substituted heteroaryl compounds and derivatives thereof |
| CA2328973A1 (en) | 1998-04-23 | 1999-10-28 | Akio Ojida | Naphthalene derivatives, their production and use |
| SE9904177D0 (sv) * | 1999-11-18 | 1999-11-18 | Astra Ab | Novel compounds |
| BR0115687A (pt) | 2000-11-27 | 2003-09-09 | Pfizer Prod Inc | Agonistas seletivos do receptor ep4 no tratamento de osteoporose |
| GB0711776D0 (en) * | 2007-06-18 | 2007-07-25 | Syngenta Participations Ag | Substituted aromatic heterocyclic compounds as fungicides |
| EP2566856B1 (en) * | 2010-05-05 | 2017-02-01 | The Board of Trustees of the University of Illionis | Compounds and methods of treating brain disorders |
| CA2846117A1 (en) | 2011-08-30 | 2013-03-07 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitor compounds |
| CN103214396B (zh) * | 2013-04-10 | 2015-01-21 | 湖北工业大学 | 3-氰基苯甲酸的生产方法 |
| CN103193658A (zh) * | 2013-04-18 | 2013-07-10 | 苏州永健生物医药有限公司 | 一种（r）-2-对硝基苯乙胺基-1-苯乙醇及其盐的合成方法 |
-
1994
- 1994-06-28 ZA ZA944647A patent/ZA944647B/xx unknown
- 1994-06-29 IL IL11015894A patent/IL110158A/xx not_active IP Right Cessation
- 1994-07-05 HU HU9503743A patent/HUT74671A/hu unknown
- 1994-07-05 MX MX9405111A patent/MX9405111A/es not_active IP Right Cessation
- 1994-07-05 PL PL94312428A patent/PL179015B1/pl unknown
- 1994-07-05 CA CA002164960A patent/CA2164960A1/en not_active Abandoned
- 1994-07-05 SK SK1600-95A patent/SK160095A3/sk unknown
- 1994-07-05 US US08/379,469 patent/US5712299A/en not_active Expired - Fee Related
- 1994-07-05 SG SG1996006908A patent/SG48081A1/en unknown
- 1994-07-05 BR BR9406925A patent/BR9406925A/pt not_active Application Discontinuation
- 1994-07-05 JP JP7504000A patent/JPH08512314A/ja not_active Withdrawn
- 1994-07-05 CZ CZ9642A patent/CZ4296A3/cs unknown
- 1994-07-05 AU AU71979/94A patent/AU691821B2/en not_active Ceased
- 1994-07-05 EP EP94921149A patent/EP0707574A1/en not_active Withdrawn
- 1994-07-05 WO PCT/SE1994/000665 patent/WO1995001968A1/en not_active Application Discontinuation
- 1994-07-05 NZ NZ268691A patent/NZ268691A/en unknown
- 1994-07-05 CN CN94192710A patent/CN1047169C/zh not_active Expired - Fee Related
-
1996
- 1996-01-04 NO NO960030A patent/NO305953B1/no not_active IP Right Cessation
- 1996-01-08 FI FI960078A patent/FI960078A0/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT74671A (en) | 1997-01-28 |
| NO960030L (no) | 1996-01-04 |
| SK160095A3 (en) | 1997-06-04 |
| NZ268691A (en) | 1997-09-22 |
| IL110158A0 (en) | 1994-10-07 |
| AU7197994A (en) | 1995-02-06 |
| PL312428A1 (en) | 1996-04-29 |
| HU9503743D0 (en) | 1996-02-28 |
| SG48081A1 (en) | 1998-04-17 |
| FI960078A (fi) | 1996-01-08 |
| IL110158A (en) | 1999-07-14 |
| EP0707574A1 (en) | 1996-04-24 |
| CN1126991A (zh) | 1996-07-17 |
| AU691821B2 (en) | 1998-05-28 |
| NO305953B1 (no) | 1999-08-23 |
| BR9406925A (pt) | 1996-07-30 |
| WO1995001968A1 (en) | 1995-01-19 |
| CZ4296A3 (en) | 1996-06-12 |
| US5712299A (en) | 1998-01-27 |
| ZA944647B (en) | 1995-01-06 |
| CA2164960A1 (en) | 1995-01-19 |
| CN1047169C (zh) | 1999-12-08 |
| JPH08512314A (ja) | 1996-12-24 |
| FI960078A0 (fi) | 1996-01-08 |
| PL179015B1 (pl) | 2000-07-31 |
| NO960030D0 (no) | 1996-01-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| MM | Annulment or lapse due to non-payment of fees |