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MX9400072A - Agentes antiinflamatorios derivados de difluoropentapeptido. - Google Patents

Agentes antiinflamatorios derivados de difluoropentapeptido.

Info

Publication number
MX9400072A
MX9400072A MX9400072A MX9400072A MX9400072A MX 9400072 A MX9400072 A MX 9400072A MX 9400072 A MX9400072 A MX 9400072A MX 9400072 A MX9400072 A MX 9400072A MX 9400072 A MX9400072 A MX 9400072A
Authority
MX
Mexico
Prior art keywords
inflammatory agents
difluoropentapeptido
agents derived
compounds
compositions
Prior art date
Application number
MX9400072A
Other languages
English (en)
Inventor
John Mcmillan Mciver
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of MX9400072A publication Critical patent/MX9400072A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

El objeto de la invención se refiere a derivados péptidos que son útiles como agentes antiinflamatorios. La presente invención implica también composiciones farmacéutica que comprenden los compuestos anteriores y métodos para tratar inflamación o dolor, utilizando tales compuestos y composiciones.
MX9400072A 1992-12-22 1994-01-03 Agentes antiinflamatorios derivados de difluoropentapeptido. MX9400072A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US99521792A 1992-12-22 1992-12-22

Publications (1)

Publication Number Publication Date
MX9400072A true MX9400072A (es) 1994-08-31

Family

ID=25541529

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9400072A MX9400072A (es) 1992-12-22 1994-01-03 Agentes antiinflamatorios derivados de difluoropentapeptido.

Country Status (22)

Country Link
US (1) US5760002A (es)
EP (1) EP0675901A1 (es)
JP (1) JPH08505143A (es)
KR (1) KR950704350A (es)
CN (1) CN1056615C (es)
AU (1) AU697299B2 (es)
BR (1) BR9307728A (es)
CA (1) CA2152267C (es)
CZ (1) CZ286126B6 (es)
FI (1) FI953106A (es)
HU (1) HUT72977A (es)
IL (1) IL108031A0 (es)
MX (1) MX9400072A (es)
NO (1) NO952485L (es)
NZ (1) NZ259274A (es)
PE (1) PE5195A1 (es)
PL (1) PL177914B1 (es)
RU (1) RU2141971C1 (es)
SG (1) SG54306A1 (es)
SK (1) SK82795A3 (es)
TW (1) TW402607B (es)
WO (1) WO1994014842A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003002845A (ja) * 2001-04-03 2003-01-08 Univ Nihon 哺乳類の硬組織治療用組成物及びその治療方法
US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
MY163048A (en) 2009-05-06 2017-08-15 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009010B1 (en) * 1978-07-18 1983-03-02 Kabi AB Bradykinin inhibiting tripeptide derivatives, process for their preparation and pharmaceutical preparations containing them
HU177098B (en) * 1979-01-04 1981-07-28 Gyogyszerkutato Intezet Process for producing new peptidyl-n-carboxy-l-arginin-a
JPS5754157A (en) * 1980-09-19 1982-03-31 Nippon Kayaku Co Ltd L-argininal derivative and its preparation
HU184368B (en) * 1981-01-13 1984-08-28 Gyogyszerkutato Intezet Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate
JPS5830300B2 (ja) * 1981-11-02 1983-06-28 三菱化学株式会社 トリペプチドおよびその誘導体の製造法
JPS58164563A (ja) * 1982-03-25 1983-09-29 Dai Ichi Pure Chem Co Ltd 新規ペプチドアルデヒド類及びその製造法
WO1984000365A1 (en) * 1982-07-19 1984-02-02 Nat Res Dev Synthetic peptides and their preparation
CS231228B1 (en) * 1982-10-01 1984-10-15 Evzen Kasafirek Biologically effective tri and tetrapeptide alkylamide derivatives and their processing method
DE3481913D1 (de) * 1983-04-27 1990-05-17 Ici America Inc Prolin-derivate.
CA1267499A (en) * 1983-07-12 1990-04-03 Cedric H. Hassall Peptide amides and aldehydes
US4816449A (en) * 1984-08-09 1989-03-28 Immunetech Pharmaceuticals Immunotherapeutic anti-inflammatory peptide agents
US4845242A (en) * 1987-04-28 1989-07-04 Georgia Tech Research Corporation Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents
HU192646B (en) * 1984-12-21 1987-06-29 Gyogyszerkutato Intezet Process for preparing new n-alkyl-peptide aldehydes
IL77748A (en) * 1985-02-04 1991-11-21 Merrell Dow Pharma Amino acid and peptide derivatives as peptidase inhibitors
US5066643A (en) * 1985-02-19 1991-11-19 Sandoz Ltd. Fluorine and chlorine statine or statone containing peptides and method of use
CH672792A5 (es) * 1985-02-19 1989-12-29 Sandoz Ag
EP0218688B1 (en) * 1985-04-19 1990-09-12 The Upjohn Company Dihalo-statine substituted renin inhibitors
ATE71934T1 (de) * 1985-06-07 1992-02-15 Ici America Inc Selektionierte difluorverbindungen.
HU200473B (en) * 1985-11-01 1990-06-28 Pfizer Process for producing polypeptides containing difluorocyclostatine and pharmaceutical compositions comprising same
GB8613704D0 (en) * 1986-06-05 1986-07-09 Ici America Inc Difluoro keto compounds
GB8613703D0 (en) * 1986-06-05 1986-07-09 Ici America Inc Difluoro peptide compounds
NZ223148A (en) * 1987-01-16 1989-10-27 Merrell Dow Pharma Peptide derivatives having peptidase inhibition activity
US5187157A (en) * 1987-06-05 1993-02-16 Du Pont Merck Pharmaceutical Company Peptide boronic acid inhibitors of trypsin-like proteases
JPH075634B2 (ja) * 1987-10-30 1995-01-25 日東紡績株式会社 トリペプチド類及びこれを含有する抗プラスミン剤
US4902781A (en) * 1987-11-24 1990-02-20 Taisho Pharmaceutical Co., Ltd. Novel tripetide derivatives
US5036054A (en) * 1988-02-11 1991-07-30 Warner-Lambert Company Renin inhibitors containing alpha-heteroatom amino acids
IL90872A0 (en) * 1988-07-08 1990-02-09 Smithkline Beckman Corp Retroviral protease binding peptides
YU30589A (en) * 1989-02-09 1991-10-31 Imunoloski Z Zagreb New adamantyl containing tripeptides and it's hydrochloride and process for preparing and use
GB8910547D0 (en) * 1989-05-08 1989-06-21 Ici America Inc Substituted ketones
US5177060A (en) * 1990-01-09 1993-01-05 Regents Of The University Of California Anti-inflammatory peptides and treatment to inhibit vascular leakage in injured tissues

Also Published As

Publication number Publication date
CA2152267A1 (en) 1994-07-07
US5760002A (en) 1998-06-02
SG54306A1 (en) 1998-11-16
CN1095072A (zh) 1994-11-16
NO952485D0 (no) 1995-06-21
WO1994014842A1 (en) 1994-07-07
NO952485L (no) 1995-08-22
PL177914B1 (pl) 2000-01-31
HUT72977A (en) 1996-06-28
FI953106A (fi) 1995-07-13
KR950704350A (ko) 1995-11-20
SK82795A3 (en) 1995-12-06
BR9307728A (pt) 1999-08-31
CZ164595A3 (en) 1995-12-13
JPH08505143A (ja) 1996-06-04
AU697299B2 (en) 1998-10-01
AU5803994A (en) 1994-07-19
CA2152267C (en) 2001-04-17
CN1056615C (zh) 2000-09-20
IL108031A0 (en) 1994-04-12
HU9501844D0 (en) 1995-08-28
PL309638A1 (en) 1995-10-30
NZ259274A (en) 1997-10-24
FI953106A0 (fi) 1995-06-21
RU95113497A (ru) 1997-06-10
PE5195A1 (es) 1995-03-08
TW402607B (en) 2000-08-21
EP0675901A1 (en) 1995-10-11
RU2141971C1 (ru) 1999-11-27
CZ286126B6 (cs) 2000-01-12

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees