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MX9305517A - PROCEDURE FOR PREPARING CERTAIN PIRROLO [3, 4-B] QUINOLINES, CERTAIN 1H-PIRANO [3 ', 4': 6, 7] INDOLIZINO [1, 2B] QUINOLIN-3,14 (4H, 12H) -DIONAS AND CERTAIN 8 -METIL-7- (OXOPROPIL) INDOLIZINO- [1, 2-B] QUINOLIN-9 (11H) -ONAS. - Google Patents

PROCEDURE FOR PREPARING CERTAIN PIRROLO [3, 4-B] QUINOLINES, CERTAIN 1H-PIRANO [3 ', 4': 6, 7] INDOLIZINO [1, 2B] QUINOLIN-3,14 (4H, 12H) -DIONAS AND CERTAIN 8 -METIL-7- (OXOPROPIL) INDOLIZINO- [1, 2-B] QUINOLIN-9 (11H) -ONAS.

Info

Publication number
MX9305517A
MX9305517A MX9305517A MX9305517A MX9305517A MX 9305517 A MX9305517 A MX 9305517A MX 9305517 A MX9305517 A MX 9305517A MX 9305517 A MX9305517 A MX 9305517A MX 9305517 A MX9305517 A MX 9305517A
Authority
MX
Mexico
Prior art keywords
certain
indolizino
quinolin
quinolines
oxopropil
Prior art date
Application number
MX9305517A
Other languages
Spanish (es)
Inventor
Joseph M Fortunak
Zhiping Zhuang
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of MX9305517A publication Critical patent/MX9305517A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/14—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a un procedimiento para preparar ciertas pirrolo[3,4-b] quinolinas, ciertas 1H-pirano[3', 4': 6, 7]indolizino[1, 2-b]quinolin-3,14(4H, 12H)-dionas, específicamente camptotencia y sus análogos, y ciertas 8-metil-7-(oxopropil)-indolizino[1,2-b]quinolin-9( 11H)-onas, específicamente mapicinocetonas y mapicinas.The present invention relates to a process for preparing certain pyrrolo [3,4-b] quinolines, certain 1H-pyran [3 ', 4': 6, 7] indolizino [1, 2-b] quinolin-3.14 ( 4H, 12H) -diones, specifically camptotence and its analogs, and certain 8-methyl-7- (oxopropyl) -indolizino [1,2-b] quinolin-9 (11H) -ones, specifically mapicinoketones and mapicins.

MX9305517A 1992-09-08 1993-09-08 PROCEDURE FOR PREPARING CERTAIN PIRROLO [3, 4-B] QUINOLINES, CERTAIN 1H-PIRANO [3 ', 4': 6, 7] INDOLIZINO [1, 2B] QUINOLIN-3,14 (4H, 12H) -DIONAS AND CERTAIN 8 -METIL-7- (OXOPROPIL) INDOLIZINO- [1, 2-B] QUINOLIN-9 (11H) -ONAS. MX9305517A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94149692A 1992-09-08 1992-09-08

Publications (1)

Publication Number Publication Date
MX9305517A true MX9305517A (en) 1994-05-31

Family

ID=25476581

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9305517A MX9305517A (en) 1992-09-08 1993-09-08 PROCEDURE FOR PREPARING CERTAIN PIRROLO [3, 4-B] QUINOLINES, CERTAIN 1H-PIRANO [3 ', 4': 6, 7] INDOLIZINO [1, 2B] QUINOLIN-3,14 (4H, 12H) -DIONAS AND CERTAIN 8 -METIL-7- (OXOPROPIL) INDOLIZINO- [1, 2-B] QUINOLIN-9 (11H) -ONAS.

Country Status (11)

Country Link
EP (1) EP0660835A4 (en)
JP (1) JPH08501104A (en)
KR (1) KR950702987A (en)
CN (1) CN1096297A (en)
AU (2) AU5102393A (en)
CA (1) CA2144048A1 (en)
MX (1) MX9305517A (en)
NZ (1) NZ255942A (en)
TW (1) TW246674B (en)
WO (1) WO1994005672A1 (en)
ZA (1) ZA936580B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6660861B1 (en) * 2003-03-27 2003-12-09 Council Of Scientific And Industrial Research Process for preparing Topotecan from 10-hydroxy-4-(S) camptothecin
CN2757510Y (en) 2004-12-06 2006-02-08 鸿富锦精密工业（深圳）有限公司 Radiator buckle
US7520313B2 (en) 2006-03-16 2009-04-21 Fu Zhun Precision Industry (Shen Zhen) Co., Ltd. Locking device for heat sink
CN105859716B (en) * 2016-05-06 2018-03-09 华东师范大学 In a kind of synthesis camptothecine compounds 56 and ring structure method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5626677B2 (en) * 1973-03-26 1981-06-19
JPS5217499A (en) * 1975-07-31 1977-02-09 Nippon Chemiphar Co Ltd Preparation of mappicine
DE2534601C2 (en) * 1975-08-02 1987-01-22 Basf Ag, 6700 Ludwigshafen Process for the preparation of camptothecin and camptothecin derivatives
CA1332413C (en) * 1987-06-25 1994-10-11 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
JP2711728B2 (en) * 1989-08-29 1998-02-10 株式会社ヤクルト本社 Novel quinoline derivative and method for producing the same
US5155225A (en) * 1990-09-28 1992-10-13 Smithkline Beecham Corporation Method for making certain pyrano[3',4':6,7]indolizino-[1,2-B]quinolinones

Also Published As

Publication number Publication date
JPH08501104A (en) 1996-02-06
CN1096297A (en) 1994-12-14
AU2859197A (en) 1997-10-23
CA2144048A1 (en) 1994-03-17
EP0660835A4 (en) 1995-08-16
WO1994005672A1 (en) 1994-03-17
ZA936580B (en) 1994-08-01
TW246674B (en) 1995-05-01
AU5102393A (en) 1994-03-29
KR950702987A (en) 1995-08-23
EP0660835A1 (en) 1995-07-05
NZ255942A (en) 1996-11-26

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