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Priority claimed from GB929210577Aexternal-prioritypatent/GB9210577D0/en
Priority claimed from GB939301438Aexternal-prioritypatent/GB9301438D0/en
Priority claimed from GB939309719Aexternal-prioritypatent/GB9309719D0/en
Application filed by Zeneca LtdfiledCriticalZeneca Ltd
Publication of MX9302859ApublicationCriticalpatent/MX9302859A/en
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
La presente invención se refiere a alcoholes terapéuticos de la fórmula I: en donde X, A, B, R1 y R2 tienen los significados dados en 1 la descripción, y las sales farmaceuticamente aceptables y los ésteres hidrolizables in vivo farmaceuticamente aceptables a los procedimientos para la preparación de los compuestos y a las composiciones farmacéuticas que comprenden a los mismos. Los compuestos son útiles como abridores del canal de potasio, y a los agentes terapéuticos en el tratamiento de la incontinencia urinaria.The present invention relates to therapeutic alcohols of the formula I: wherein X, A, B, R1 and R2 have the meanings given in the description, and the pharmaceutically acceptable salts and the pharmaceutically acceptable in vivo hydrolyzable esters of the processes for the preparation of the compounds and the pharmaceutical compositions comprising them. The compounds are useful as potassium channel openers, and therapeutic agents in the treatment of urinary incontinence.
PEPTIDES RELATED TO DOLASTATIN, PROCEDURE FOR PREPARING THEM, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE USE OF THE SAME FOR THE PREPARATION OF SUCH PHARMACEUTICAL COMPOSITIONS.
PHARMACEUTICAL COMPOSITIONS, A PROCEDURE FOR PREPARING SUCH COMPOSITIONS AND USE OF SUCH COMPOSITIONS IN THE TREATMENT OF OPHTHALMIC DISEASES AND METHODS FOR TREATING SUCH DISEASES
BENCILOXICARBONYLGUANIDINES REPLACED AS INHIBITORS OF THE SODIUM PROTECTOR EXCHANGER, PROCEDURE FOR ITS PREPARATION, ITS USE AS A MEDICINAL PRODUCT OR DIAGNOSTIC AGENT, AS WELL AS A MEDICINAL PRODUCT CONTAINING THEM.
3-CHLORINE-6-HYDROXY-5-METHYL-BENZOACID DERIVATIVES THE RELEVANT PHARMACEUTICAL COMPOSITIONS, COMPOSITIONS TO GROW CERTAIN ANIMALS AND THEIR PRODUCTION.