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MX9300136A - Alfa-aril-alfa-hidroxi-beta-imidazolinil-propionamidas, procedimiento para su obtencion y medicamentos que las contienen. - Google Patents

Alfa-aril-alfa-hidroxi-beta-imidazolinil-propionamidas, procedimiento para su obtencion y medicamentos que las contienen.

Info

Publication number
MX9300136A
MX9300136A MX9300136A MX9300136A MX9300136A MX 9300136 A MX9300136 A MX 9300136A MX 9300136 A MX9300136 A MX 9300136A MX 9300136 A MX9300136 A MX 9300136A MX 9300136 A MX9300136 A MX 9300136A
Authority
MX
Mexico
Prior art keywords
alfa
propionamidas
imidazolinil
hidroxi
aril
Prior art date
Application number
MX9300136A
Other languages
English (en)
Inventor
Wilfried Draber
Hilmar Bischoff
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX9300136A publication Critical patent/MX9300136A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/26—Radicals substituted by carbon atoms having three bonds to hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a nuevas Ó-aril-Ó-hidroxi-B-imidazolinil-propionamidas de fórmula general (I) en la cual R1 a R4 y X tienen el significado mencionado en la descripción, un procedimiento para su obtención y su empleo en medicamentos.
MX9300136A 1992-01-23 1993-01-12 Alfa-aril-alfa-hidroxi-beta-imidazolinil-propionamidas, procedimiento para su obtencion y medicamentos que las contienen. MX9300136A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4201709A DE4201709A1 (de) 1992-01-23 1992-01-23 (alpha)-aryl-(alpha)-hydroxy-ss-imidazolinyl-propionsaeureamide

Publications (1)

Publication Number Publication Date
MX9300136A true MX9300136A (es) 1993-07-01

Family

ID=6450062

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9300136A MX9300136A (es) 1992-01-23 1993-01-12 Alfa-aril-alfa-hidroxi-beta-imidazolinil-propionamidas, procedimiento para su obtencion y medicamentos que las contienen.

Country Status (22)

Country Link
US (1) US5334610A (es)
EP (1) EP0552631B1 (es)
JP (1) JPH05286942A (es)
KR (1) KR930016401A (es)
CN (1) CN1075714A (es)
AT (1) ATE158576T1 (es)
AU (1) AU650807B2 (es)
CA (1) CA2087650A1 (es)
CZ (1) CZ282024B6 (es)
DE (2) DE4201709A1 (es)
DK (1) DK0552631T3 (es)
ES (1) ES2107562T3 (es)
GR (1) GR3025179T3 (es)
HU (1) HUT63394A (es)
IL (1) IL104444A (es)
MX (1) MX9300136A (es)
MY (1) MY108826A (es)
NZ (1) NZ245726A (es)
PL (1) PL172005B1 (es)
SK (1) SK278548B6 (es)
TW (1) TW232011B (es)
ZA (1) ZA93477B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403818B1 (en) 2000-02-28 2002-06-11 Eisai Co., Ltd. Process for producing α-hydroxy-carbonyl compound
CA2482035A1 (en) * 2002-04-18 2003-10-30 University Of Virginia Patent Foundation Novel sodium channel blockers
JP2006509015A (ja) * 2002-12-04 2006-03-16 メルク　エンド　カムパニー　インコーポレーテッド スピロ環尿素、そのような化合物を含有する組成物、及び使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7605609A (nl) * 1975-05-30 1976-12-02 Scherico Ltd Werkwijze voor het bereiden van nieuwe 2-imidazolinen.
DE2614240C3 (de) * 1976-04-02 1980-03-06 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Acylcyaniden
JPS5936885B2 (ja) * 1976-06-24 1984-09-06 第一製薬株式会社 糖尿病治療剤
US4136188A (en) * 1976-06-25 1979-01-23 Daiichi Seiyaku Co., Ltd. Treatment of diabetes with 2-substituted-1,3-diazacyclic compounds
US4226876A (en) * 1976-12-20 1980-10-07 Burroughs Wellcome Co. Arthropodicidal imidazoline derivatives
DK344489D0 (da) * 1989-07-12 1989-07-12 Novo Nordisk As Substituerede 2-imidazoliner og fremstilling og anvendelse deraf

Also Published As

Publication number Publication date
AU3188893A (en) 1993-07-29
AU650807B2 (en) 1994-06-30
CZ372292A3 (en) 1993-12-15
SK372292A3 (en) 1997-09-10
DE59307401D1 (de) 1997-10-30
DK0552631T3 (da) 1998-05-11
EP0552631A1 (de) 1993-07-28
JPH05286942A (ja) 1993-11-02
HUT63394A (en) 1993-08-30
PL172005B1 (pl) 1997-07-31
IL104444A0 (en) 1993-05-13
MY108826A (en) 1996-11-30
TW232011B (es) 1994-10-11
DE4201709A1 (de) 1993-07-29
ES2107562T3 (es) 1997-12-01
CZ282024B6 (cs) 1997-04-16
CA2087650A1 (en) 1993-07-24
IL104444A (en) 1997-06-10
PL297491A1 (en) 1993-08-09
KR930016401A (ko) 1993-08-26
ZA93477B (en) 1993-08-23
HU9300181D0 (en) 1993-04-28
NZ245726A (en) 1996-01-26
SK278548B6 (en) 1997-09-10
US5334610A (en) 1994-08-02
ATE158576T1 (de) 1997-10-15
CN1075714A (zh) 1993-09-01
EP0552631B1 (de) 1997-09-24
GR3025179T3 (en) 1998-02-27

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