MX9204138A - Compuestos ditiano, procedimiento para su obtencion y medicamentos que los contienen - Google Patents
Compuestos ditiano, procedimiento para su obtencion y medicamentos que los contienenInfo
- Publication number
- MX9204138A MX9204138A MX9204138A MX9204138A MX9204138A MX 9204138 A MX9204138 A MX 9204138A MX 9204138 A MX9204138 A MX 9204138A MX 9204138 A MX9204138 A MX 9204138A MX 9204138 A MX9204138 A MX 9204138A
- Authority
- MX
- Mexico
- Prior art keywords
- formula
- compounds
- ditiane
- procedure
- obtaining
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/08—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
Compuestos de l a fórmula: (FORMULA) en donde R significa un radical de la fórmula (FORMULA) y R1, R2, R3, R4, R5, R6, R7, X, Y y Z tienen el significado expuesto en la reivindicación 1, con la excepción de rac-N-(3,4-dimetoxifenetil)-2-(3,4-dimetoxifenil)- beta, n-dimetil-m-ditian-2-propilamina, así como sus sales de adición de ácido tienen relevantes propiedades contra células tumorales malignas multi-resistentes y contra resistencia a cloroquina, y son por tanto apropiados para reducir y/o eliminar resistencia múltiple a citostáticos en el tratamiento de tumores o para reducir y/o eliminar resistencia a cloroquina en el tratamiento de malaria.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH214491 | 1991-07-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9204138A true MX9204138A (es) | 1993-07-01 |
Family
ID=4226902
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9204138A MX9204138A (es) | 1991-07-18 | 1992-07-15 | Compuestos ditiano, procedimiento para su obtencion y medicamentos que los contienen |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US5302727A (es) |
| EP (1) | EP0523493A1 (es) |
| JP (1) | JPH05208972A (es) |
| KR (1) | KR930002341A (es) |
| CN (1) | CN1031754C (es) |
| AU (1) | AU657142B2 (es) |
| BR (1) | BR9202719A (es) |
| CA (1) | CA2074062A1 (es) |
| CZ (1) | CZ281619B6 (es) |
| FI (1) | FI923292A (es) |
| HU (1) | HUT62285A (es) |
| IE (1) | IE922338A1 (es) |
| IL (1) | IL102477A (es) |
| MX (1) | MX9204138A (es) |
| NO (1) | NO922846L (es) |
| NZ (1) | NZ243545A (es) |
| TW (1) | TW223071B (es) |
| UY (1) | UY23447A1 (es) |
| ZA (1) | ZA925185B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2198752A1 (en) | 1994-08-31 | 1996-03-07 | Jason Scott Sawyer | Methods for identifying and treating resistant tumors |
| GB9524681D0 (en) | 1995-12-02 | 1996-01-31 | Knoll Ag | Chemical process |
| US6664287B2 (en) * | 2000-03-15 | 2003-12-16 | Bethesda Pharmaceuticals, Inc. | Antioxidants |
| US6376514B1 (en) | 2000-10-17 | 2002-04-23 | The Procter & Gamble Co. | Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof |
| US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
| AU2012362105B2 (en) * | 2011-12-30 | 2017-09-07 | Reviva Pharmaceuticals, Inc. | Compositions, synthesis, and methods of using phenylcycloalkylmethylamine derivatives |
| CN105085471B (zh) * | 2014-05-16 | 2019-06-11 | 兰州大学 | 一种2-取代-1，3-二噻烷衍生物的制备方法 |
| CN104710404B (zh) * | 2015-03-31 | 2016-03-23 | 西安科技大学 | 一种取代-1,3-二噻烷类化合物的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4003914A (en) * | 1973-12-21 | 1977-01-18 | Hoffmann-La Roche Inc. | Sulphur containing derivatives |
| US4127588A (en) * | 1976-10-01 | 1978-11-28 | Hoffmann-La Roche Inc. | Sulphur containing derivatives |
-
1991
- 1991-07-04 ZA ZA925185A patent/ZA925185B/xx unknown
-
1992
- 1992-07-06 EP EP92111406A patent/EP0523493A1/de not_active Withdrawn
- 1992-07-13 IL IL10247792A patent/IL102477A/en not_active IP Right Cessation
- 1992-07-13 CZ CS922189A patent/CZ281619B6/cs unknown
- 1992-07-14 NZ NZ243545A patent/NZ243545A/en unknown
- 1992-07-15 HU HU9202320A patent/HUT62285A/hu unknown
- 1992-07-15 US US07/914,241 patent/US5302727A/en not_active Expired - Fee Related
- 1992-07-15 MX MX9204138A patent/MX9204138A/es unknown
- 1992-07-16 KR KR1019920012743A patent/KR930002341A/ko not_active Application Discontinuation
- 1992-07-16 AU AU20349/92A patent/AU657142B2/en not_active Ceased
- 1992-07-16 CA CA002074062A patent/CA2074062A1/en not_active Abandoned
- 1992-07-17 FI FI923292A patent/FI923292A/fi not_active Application Discontinuation
- 1992-07-17 NO NO92922846A patent/NO922846L/no unknown
- 1992-07-17 UY UY23447A patent/UY23447A1/es unknown
- 1992-07-17 IE IE233892A patent/IE922338A1/en not_active Application Discontinuation
- 1992-07-17 BR BR929202719A patent/BR9202719A/pt not_active Application Discontinuation
- 1992-07-17 CN CN92105720A patent/CN1031754C/zh not_active Expired - Fee Related
- 1992-07-20 JP JP4213272A patent/JPH05208972A/ja active Pending
- 1992-11-03 TW TW081108774A patent/TW223071B/zh active
-
1994
- 1994-01-24 US US08/186,720 patent/US5405866A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05208972A (ja) | 1993-08-20 |
| BR9202719A (pt) | 1993-03-23 |
| TW223071B (es) | 1994-05-01 |
| FI923292A (fi) | 1993-01-19 |
| IL102477A (en) | 1996-09-12 |
| CN1031754C (zh) | 1996-05-08 |
| HU9202320D0 (en) | 1992-10-28 |
| NZ243545A (en) | 1994-11-25 |
| HUT62285A (en) | 1993-04-28 |
| CZ281619B6 (cs) | 1996-11-13 |
| US5405866A (en) | 1995-04-11 |
| AU2034992A (en) | 1993-01-21 |
| US5302727A (en) | 1994-04-12 |
| FI923292A0 (fi) | 1992-07-17 |
| CZ218992A3 (en) | 1993-02-17 |
| IL102477A0 (en) | 1993-01-14 |
| AU657142B2 (en) | 1995-03-02 |
| NO922846D0 (no) | 1992-07-17 |
| UY23447A1 (es) | 1993-01-07 |
| CN1068569A (zh) | 1993-02-03 |
| KR930002341A (ko) | 1993-02-23 |
| EP0523493A1 (de) | 1993-01-20 |
| CA2074062A1 (en) | 1993-01-19 |
| NO922846L (no) | 1993-01-19 |
| ZA925185B (en) | 1993-04-29 |
| IE922338A1 (en) | 1993-01-27 |
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