[go: up one dir, main page]

MX9202118A - Formulacion de tableta que tiene una estructura que comprende granulos compactados de una mezcla de medicamento y un desintegrante inter-granular y proceso para su fabricacion. - Google Patents

Formulacion de tableta que tiene una estructura que comprende granulos compactados de una mezcla de medicamento y un desintegrante inter-granular y proceso para su fabricacion.

Info

Publication number
MX9202118A
MX9202118A MX9202118A MX9202118A MX9202118A MX 9202118 A MX9202118 A MX 9202118A MX 9202118 A MX9202118 A MX 9202118A MX 9202118 A MX9202118 A MX 9202118A MX 9202118 A MX9202118 A MX 9202118A
Authority
MX
Mexico
Prior art keywords
inter
manufacture
tablet formulation
medicinal mixture
compacted granules
Prior art date
Application number
MX9202118A
Other languages
English (en)
Inventor
Luis Carvajal Martin
Juan De Dios Romero
Original Assignee
Beecham Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Lab Sa filed Critical Beecham Lab Sa
Publication of MX9202118A publication Critical patent/MX9202118A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX9202118A 1991-05-08 1992-05-07 Formulacion de tableta que tiene una estructura que comprende granulos compactados de una mezcla de medicamento y un desintegrante inter-granular y proceso para su fabricacion. MX9202118A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919109862A GB9109862D0 (en) 1991-05-08 1991-05-08 Pharmaceutical formulations

Publications (1)

Publication Number Publication Date
MX9202118A true MX9202118A (es) 1993-03-01

Family

ID=10694582

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9202118A MX9202118A (es) 1991-05-08 1992-05-07 Formulacion de tableta que tiene una estructura que comprende granulos compactados de una mezcla de medicamento y un desintegrante inter-granular y proceso para su fabricacion.

Country Status (33)

Country Link
US (3) US6110497A (es)
EP (3) EP0787487B1 (es)
JP (1) JPH06507396A (es)
KR (1) KR100228450B1 (es)
CN (2) CN1056277C (es)
AP (1) AP328A (es)
AT (3) ATE203400T1 (es)
AU (1) AU659836B2 (es)
BR (1) BR9205948A (es)
CA (1) CA2102630C (es)
CZ (1) CZ291795B6 (es)
DE (3) DE69233464T2 (es)
DK (1) DK0585252T3 (es)
ES (3) ES2212034T3 (es)
FI (1) FI110354B (es)
GB (1) GB9109862D0 (es)
GR (1) GR3036937T3 (es)
HU (1) HU219348B (es)
IE (1) IE921472A1 (es)
IL (1) IL101795A (es)
MA (1) MA22522A1 (es)
MX (1) MX9202118A (es)
MY (1) MY111879A (es)
NO (1) NO312224B1 (es)
NZ (1) NZ242625A (es)
PT (1) PT100458B (es)
SA (1) SA92130069B1 (es)
SG (1) SG55163A1 (es)
SK (1) SK282333B6 (es)
TW (1) TW240172B (es)
WO (1) WO1992019227A2 (es)
YU (1) YU49069B (es)
ZA (1) ZA923272B (es)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9109862D0 (en) * 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations
GB9416599D0 (en) * 1994-08-17 1994-10-12 Smithkline Beecham Plc Pharmaceutical formulation
GB9416600D0 (en) 1994-08-17 1994-10-12 Smithkline Beecham Plc Pharmaceutical formulation
ES2079327B1 (es) * 1994-12-13 1996-08-01 Lilly Sa Formulaciones farmaceuticas de cefaclor.
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
EP0843552A2 (en) * 1995-08-12 1998-05-27 Smithkline Beecham Plc Pharmaceutical formulations
AU711441B2 (en) 1995-09-07 1999-10-14 Smithkline Beecham Plc Pharmaceutical formulation
DK0890359T3 (da) * 1996-02-29 2002-07-01 Fujisawa Pharmaceutical Co Beta-Lactam-antibiotikumholdige tabletter og fremgangsmåde til fremstilling deraf
AT407701B (de) * 1996-08-12 2001-05-25 Biochemie Gmbh Zur direkttablettierung geeignete mischung, die als wesentliche komponenten amoxicillin-trihydrat und das kaliumsalz der clavulansäure enthält und verfahren zur herstellung dieser mischung
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
US6893664B1 (en) 1996-06-17 2005-05-17 Powderject Research Limited Particle delivery techniques
US5837292A (en) * 1996-07-03 1998-11-17 Yamanouchi Europe B.V. Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug
GB9616536D0 (en) * 1996-08-06 1996-09-25 Quadrant Holdings Cambridge Co-amoxiclav dosage form
AU6496498A (en) * 1997-02-07 1998-08-26 Gist-Brocades B.V. Homogeneous granulated formulations for dose sipping technology
US20030124187A1 (en) * 1997-02-14 2003-07-03 Smithkline Beecham Laboratoires Pharmaceutiques, Pharmaceutical formulations comprising amoxycillin and clavulanate
ATE243516T1 (de) * 1997-02-14 2003-07-15 Glaxosmithkline Lab Sas Amoxicillin und clavulanat enthaltende arzneizubereitungen
CN1268888A (zh) * 1997-08-29 2000-10-04 Dsm公司 不含赋形剂的颗粒
DE19820801A1 (de) * 1998-05-09 1999-11-25 Gruenenthal Gmbh Orale Arzneiformen mit reproduzierbarer Wirkstofffreisetzung von Gatifloxacin oder pharmazeutisch verwendbaren Salzen oder Hydraten
WO2000025751A2 (en) * 1998-10-30 2000-05-11 Fuisz International Ltd. Improved amoxycillin and clavulanate composition
US6177421B1 (en) 1999-05-04 2001-01-23 Fuisz International Ltd. Amoxicillin and clavulanate composition
IE990159A1 (en) * 1999-02-26 2000-09-20 Fuisz Internat Ltd Storage Stable Amoxycillin and Clavulanate Suspension Composition.
MXPA01009808A (es) 1999-04-01 2002-04-24 Dsm Nv Aglomerados por cristalizacion.
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US6294199B1 (en) 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US7250176B1 (en) 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
BE1013309A5 (fr) * 1999-04-13 2001-11-06 Beecham Pharm Pte Ltd Formulations pharmaceutiques nouvelles comprenant l'amoxycilline et du clavulanate de potassium.
US20020006433A1 (en) * 1999-04-29 2002-01-17 Nigel P. Davidson Pharmaceutical formulations
GB9930578D0 (en) * 1999-12-23 2000-02-16 Smithkline Beecham Plc Pharmaceutical formulations
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
EP1330236A2 (en) 2000-10-12 2003-07-30 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20040043981A1 (en) * 2000-10-20 2004-03-04 Stefan Horkovics-Kovats Pharmaceutical composistions
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
US6720000B2 (en) 2001-03-19 2004-04-13 Three Rivers Pharmaceutical, Llc Process for producing wet ribavirin pellets
AT413983B (de) * 2001-04-12 2006-08-15 Sandoz Ag K-clavulanat in der form eines granulates
AT412344B (de) * 2001-04-12 2005-01-25 Sandoz Ag Hydrophobisierte teilchen von k-clavulanat
AU2003238670A1 (en) * 2002-04-05 2003-10-27 Cadila Healthcare Limited Fast disintegrating oral dosage forms
KR20050062514A (ko) * 2002-07-16 2005-06-23 랜박시 래보러터리스 리미티드 경구 투여용 분산성 정제
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US7538094B2 (en) 2002-09-19 2009-05-26 Three Rivers Pharmacueticals, Llc Composition containing ribavirin and use thereof
CA2406592C (en) * 2002-10-04 2003-09-30 Duchesnay Inc. Method of preparing pharmaceutical dosage forms containing multiple active ingredients
JP2006528185A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
CA2533178C (en) * 2003-07-21 2014-03-11 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
WO2005009368A2 (en) * 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
FR2858556B1 (fr) * 2003-08-06 2006-03-10 Galenix Innovations Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation
EP1653925A1 (en) 2003-08-11 2006-05-10 Advancis Pharmaceutical Corporation Robust pellet
EP1653924A4 (en) 2003-08-12 2009-09-09 Middlebrook Pharmaceuticals In ANTIBIOTICS, USE AND FORMULATION ASSOCIATED
US20050089502A1 (en) * 2003-08-21 2005-04-28 Todd Schansberg Effervescent delivery system
AU2004270170B2 (en) * 2003-08-29 2011-01-27 Shionogi, Inc. Antibiotic product, use and formulation thereof
AU2004273830B2 (en) * 2003-09-15 2011-03-24 Shionogi, Inc. Antibiotic product, use and formulation thereof
EP1686963A1 (en) * 2003-10-27 2006-08-09 PSivida Inc. Suspension delivery system for the sustained and controlled local release of pharmaceuticals
EP1701705A4 (en) * 2003-12-24 2007-08-08 Advancis Pharmaceutical Corp IMPROVED ABSORPTION OF DOSAGE FORMS WITH MODIFIED RELEASE
JP2007523125A (ja) * 2004-02-24 2007-08-16 サンド・アクチエンゲゼルシヤフト アモキシシリンインスタント顆粒
WO2005115347A1 (en) * 2004-05-31 2005-12-08 Sam-A Pharmaceuticals Co., Ltd. Dispersible tablet comprising beta lactam antibiotics and process for preparing the same
EP1771158A4 (en) * 2004-07-02 2008-03-12 Advancis Pharmaceutical Corp TABLET FOR PULSE DISTRIBUTION
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
ES2346147T3 (es) 2005-03-03 2010-10-11 Janssen Pharmaceutica Nv Derivados de oxa-diaza-espiro-(5.5)-undecanona sustituidos y su uso como antagonistas de las neuroquininas.
US8604200B2 (en) 2005-03-08 2013-12-10 Janssen Pharmaceutica N.V. Diaza-spiro-{4,4}-nonane derivatives as neurokinin (NK1) antagonists
WO2007058397A1 (en) * 2005-11-17 2007-05-24 Gl Pharmtech Corp. A dispersible tablet comprising the mixture of amoxicillin and clavulanic acid or its salts and processes for preparing the same
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
CA2873524C (en) 2006-05-04 2018-02-20 Boehringer Ingelheim International Gmbh A polymeric form of 1-((4-methyl-quinazolin-2-yl)methyl)-3-7-(2-butyn-1-yl)-8-(3-(r)-aminopiperidin-1-yl)xanthine
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
CA2563690C (en) * 2006-10-12 2014-10-07 Pharmascience Inc. Pharmaceutical compositions comprising intra- and extra- granular fractions
FI20070521L (fi) * 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
US8951562B2 (en) * 2006-11-10 2015-02-10 Atacama Labs Oy Method and apparatus or dry granulation
BRPI0807581A2 (pt) 2007-02-23 2014-07-01 Gilead Science Inc Moduladores de propriedades farmacocinéticas de produtos terapêuticos
CN101918004A (zh) 2007-10-26 2010-12-15 瑞恩药品公司 克拉维酸的药物制剂
AR071175A1 (es) 2008-04-03 2010-06-02 Boehringer Ingelheim Int Composicion farmaceutica que comprende un inhibidor de la dipeptidil-peptidasa-4 (dpp4) y un farmaco acompanante
DK2296633T3 (en) 2008-05-02 2016-01-11 Gilead Sciences Inc USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PREPARABILITY OF A PHARMACEUTICAL AGENT
CA2723409C (en) 2008-05-09 2016-11-08 Atacama Labs Oy Method and apparatus for dry granulation
KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
TW201028168A (en) * 2008-12-19 2010-08-01 Solvay Pharm Bv Precompacted fast-disintegrating formulations of compounds with a low oral bioavailability
CN107011345A (zh) 2008-12-23 2017-08-04 勃林格殷格翰国际有限公司 有机化合物的盐形式
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
BR112012009857A8 (pt) 2009-10-26 2023-04-11 Merck Sharp & Dohme Composições farmacêuticas sólidas contendo um inibidor de integrase
JP2013512229A (ja) 2009-11-27 2013-04-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 遺伝子型が同定された糖尿病患者のリナグリプチン等のｄｄｐ−ｉｖ阻害薬による治療
US20120294937A1 (en) 2009-12-29 2012-11-22 Novartis Ag New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080502A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
AU2011249771A1 (en) * 2010-05-05 2012-11-01 Boehringer Ingelheim International Gmbh Pharmaceutical formulations comprising pioglitazone and linagliptin
ES2935300T3 (es) 2010-05-05 2023-03-03 Boehringer Ingelheim Int Combiterapia
CA2803504C (en) 2010-06-24 2022-08-30 Boehringer Ingelheim International Gmbh A combination for diabetes therapy comprising linagliptin and a long-acting insulin
US20170087134A1 (en) * 2010-07-12 2017-03-30 Salix Pharmaceuticals, Ltd Formulations of rifaximin and uses thereof
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
JP5876150B2 (ja) 2011-07-15 2016-03-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 置換キナゾリン、これらの調製及び医薬組成物中のこれらの使用
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
EP3685839A1 (en) 2012-05-14 2020-07-29 Boehringer Ingelheim International GmbH Linagliptin for use in the treatment of albuminuria and kidney related diseases
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
EP2882423A1 (en) * 2012-08-07 2015-06-17 Sandoz AG Uncoated tablet comprising granules including a -lactam antibiotic and highly dispersed silicone dioxide
JP2014079286A (ja) * 2012-10-12 2014-05-08 Hiroaki Koga 抗菌剤入容器
ES2950384T3 (es) 2014-02-28 2023-10-09 Boehringer Ingelheim Int Uso médico de un inhibidor de DPP-4
WO2017211979A1 (en) 2016-06-10 2017-12-14 Boehringer Ingelheim International Gmbh Combinations of linagliptin and metformin
CA3038312A1 (en) 2016-09-30 2018-04-05 Salix Pharmaceuticals, Inc. Solid dispersion forms of rifaximin
PL3528791T3 (pl) * 2016-10-24 2024-04-02 Janssen Sciences Ireland Unlimited Company Kompozycje dyspergowalne

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552416A (en) * 1975-08-12 1979-09-12 Beecham Group Ltd Pharmaceutical compositions
JO984B1 (en) * 1977-10-11 1979-12-01 بيتشام غروب ليمتد A dry pharmaceutical compound with a suitable dosage unit for oral administration
DE3134591A1 (de) * 1981-09-01 1983-03-10 Bayer Ag, 5090 Leverkusen Neue arzneimittelpraeparationen fuer glykosidhydrolasen-inhibitoren
EP0281200B1 (en) * 1987-03-02 1994-01-19 Yamanouchi Europe B.V. Pharmaceutical composition, pharmaceutical granulate and process for their preparation
US5275823A (en) * 1989-04-27 1994-01-04 Smith Kline & French Laboratories Ltd. Pharmaceutical compositions
US5861172A (en) * 1991-05-08 1999-01-19 Laboratorios Beecham Sa Pharmaceutical formulations of compacted granulates of β-lactam antibiotics
GB9109862D0 (en) * 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations

Also Published As

Publication number Publication date
FI110354B (fi) 2002-12-31
US6544558B2 (en) 2003-04-08
AP9200382A0 (en) 1992-07-31
AU1649892A (en) 1992-12-21
GR3036937T3 (en) 2002-01-31
ATE203400T1 (de) 2001-08-15
PT100458A (pt) 1993-08-31
PT100458B (pt) 1999-07-30
GB9109862D0 (en) 1991-07-03
ES2235210T3 (es) 2005-07-01
US6110497A (en) 2000-08-29
IL101795A0 (en) 1992-12-30
EP0783889A1 (en) 1997-07-16
AU659836B2 (en) 1995-06-01
SG55163A1 (en) 1998-12-21
CN1155370C (zh) 2004-06-30
BR9205948A (pt) 1994-11-08
YU49069B (sh) 2003-08-29
NO934009D0 (no) 1993-11-05
DK0585252T3 (da) 2001-11-12
DE69231965D1 (de) 2001-08-30
MA22522A1 (fr) 1992-12-31
MY111879A (en) 2001-02-28
EP0787487A1 (en) 1997-08-06
SA92130069B1 (ar) 2005-04-16
CN1265882A (zh) 2000-09-13
WO1992019227A2 (en) 1992-11-12
HU9303143D0 (en) 1994-01-28
ZA923272B (en) 1993-03-31
NO312224B1 (no) 2002-04-15
US20020064562A1 (en) 2002-05-30
EP0783889B1 (en) 2003-10-29
HU219348B (en) 2001-03-28
EP0585252B1 (en) 2001-07-25
WO1992019227A3 (en) 1992-12-23
DE69233239D1 (de) 2003-12-04
TW240172B (es) 1995-02-11
SK282333B6 (sk) 2002-01-07
EP0787487B1 (en) 2004-12-22
KR100228450B1 (ko) 1999-11-01
CZ237993A3 (en) 1994-03-16
ATE252900T1 (de) 2003-11-15
SK112793A3 (en) 1994-06-08
IE921472A1 (en) 1992-11-18
ATE285227T1 (de) 2005-01-15
YU47892A (sh) 1994-12-28
NO934009L (no) 1993-11-05
CA2102630C (en) 2004-01-13
NZ242625A (en) 1994-08-26
IL101795A (en) 1996-10-16
ES2161690T3 (es) 2001-12-16
FI934914A0 (fi) 1993-11-05
HUT67020A (en) 1995-01-30
FI934914A (fi) 1993-11-05
JPH06507396A (ja) 1994-08-25
CN1056277C (zh) 2000-09-13
DE69231965T2 (de) 2002-04-04
DE69233464D1 (de) 2005-01-27
AP328A (en) 1994-03-23
ES2212034T3 (es) 2004-07-16
CA2102630A1 (en) 1992-11-09
DE69233239T2 (de) 2004-08-19
CN1067577A (zh) 1993-01-06
CZ291795B6 (cs) 2003-05-14
EP0585252A1 (en) 1994-03-09
US6352720B1 (en) 2002-03-05
DE69233464T2 (de) 2006-04-13

Similar Documents

Publication Publication Date Title
MX9202118A (es) Formulacion de tableta que tiene una estructura que comprende granulos compactados de una mezcla de medicamento y un desintegrante inter-granular y proceso para su fabricacion.
AR008462A1 (es) COMPOSICIoN FARMACÉUTICA QUE COMPRENDE OLANZAPINA Y CLORHIDRATO DE FLUOXETINA Y USO DE DICHA COMPOSICIoN PARA LA FABRICACIoN DE UN MEDICAMENTO.
MX9206938A (es) Nuevos derivados peptidos, proceso para su preparacion y preparacion farmaceutica que comprende tales derivados.
ATE22007T1 (de) Pharmazeutische mischung.
MX9200374A (es) Nuevos esteres esteroides, procedimiento para su preparacion y preparacion farmaceutica que los contiene.
PT86870A (pt) Pharmaceutical tablet pharmaceutical granulate and process for their preparation
NO986157L (no) Granulat for fremstilling av raskt-desintegrerende og raskt oppl°selige blandinger inneholdende en h°y mengde legemiddel
MX9306499A (es) Composiciones farmaceuticas que contienen una anfetamina.
ES503011A0 (es) Un procedimiento para la preparacion de una formulacion por-tadora de farmacos,biodegradable y magneticamente localiza- ble
ES2163511T3 (es) Preparacion farmaceutica conteniendo glucagon.
MX9203236A (es) Composicion farmaceutica que comprende una ciclosporina.
ATA119188A (de) Pharmazeutische granulate und verfahren zu ihrer herstellung
DE69300913D1 (de) Polymorph Terazosin und pharmazeutische Zusammenstellung.
MX9202748A (es) Compuesto de arileter, proceso para su obtencion y composicion farmaceutica que los contiene.
GB2149413B (en) Sustained release pharmaceutical tablets and process for the preparation thereof
AR002982A1 (es) Benzonitrilos y benzofluoruros, un procedimiento para prepararlos, su empleo para preparar médicamentos, un médicamento hecho a base de estos compuestos, las preparaciónes farmacéuticas que los contienen y un procedimiento para obtener estas preparaciónes farmacéuticas.
NO914049L (no) Materialer som kan anvendes som saarbandasjer og for administrering av medikamenter
MX9201710A (es) Carbamatos de rapamicina y composicion farmaceutica que los contiene.
BR9104948A (pt) Compostos,processo para a sua producao,agente farmaceutico e processo para a sua producao
BR9202325A (pt) Composto,processo para a sua preparacao,preparado farmaceutico e processo para a sua preparacao
EP0347748A3 (en) Pharmaceutical granules and tablets made therefrom
MX9201848A (es) Antiserotoninas, procedimiento para su preparacion y medicamentos que las contienen.
NO922998L (no) Perforert drivkrutt, anordning for dets fremstilling og anvendelse av anordningen
NO180450C (no) Farmasöytiske formuleringer og fremgangsmåte for fremstilling av form II diritromycin
DE69632787D1 (de) Pharmazeutische pellets

Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees