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MX371291B - 2-(2,4-difluorofenil)-1,1-difluoro-1-(5-sustituido-piridin-2-il)- 3-(1h-tetrazol-1-il)propan-2-oles y procedimientos para su preparacion. - Google Patents

2-(2,4-difluorofenil)-1,1-difluoro-1-(5-sustituido-piridin-2-il)- 3-(1h-tetrazol-1-il)propan-2-oles y procedimientos para su preparacion.

Info

Publication number
MX371291B
MX371291B MX2016012058A MX2016012058A MX371291B MX 371291 B MX371291 B MX 371291B MX 2016012058 A MX2016012058 A MX 2016012058A MX 2016012058 A MX2016012058 A MX 2016012058A MX 371291 B MX371291 B MX 371291B
Authority
MX
Mexico
Prior art keywords
ols
tetrazol
difluorophenyl
propan
difluoro
Prior art date
Application number
MX2016012058A
Other languages
English (en)
Other versions
MX2016012058A (es
Inventor
J Hoekstra William
T Sullenberger Michael
Knueppel Daniel
Whiteker Greg
Renga Jim
Original Assignee
Viamet Pharmaceuticals Nc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viamet Pharmaceuticals Nc Inc filed Critical Viamet Pharmaceuticals Nc Inc
Publication of MX2016012058A publication Critical patent/MX2016012058A/es
Publication of MX371291B publication Critical patent/MX371291B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/713—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with four or more nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/127—Preparation from compounds containing pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Proporcionados en este documento están los 2-(2,4-difluorofenil)-1 ,1-difluoro-1-(5-sustituido-piridin-2-iI)-3-(1H-tetrazol-1-iI)-pr opan-2-oles y procedimientos para su preparación.
MX2016012058A 2014-03-19 2015-03-19 2-(2,4-difluorofenil)-1,1-difluoro-1-(5-sustituido-piridin-2-il)- 3-(1h-tetrazol-1-il)propan-2-oles y procedimientos para su preparacion. MX371291B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461955661P 2014-03-19 2014-03-19
PCT/US2015/021519 WO2015143188A1 (en) 2014-03-19 2015-03-19 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1h-tetrazol-1-yl)propan-2-ols and proceses for their preparation

Publications (2)

Publication Number Publication Date
MX2016012058A MX2016012058A (es) 2017-01-19
MX371291B true MX371291B (es) 2020-01-24

Family

ID=54145331

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016012058A MX371291B (es) 2014-03-19 2015-03-19 2-(2,4-difluorofenil)-1,1-difluoro-1-(5-sustituido-piridin-2-il)- 3-(1h-tetrazol-1-il)propan-2-oles y procedimientos para su preparacion.

Country Status (10)

Country Link
US (1) US9914726B2 (es)
EP (1) EP3119753B1 (es)
JP (1) JP6613391B2 (es)
KR (1) KR102441242B1 (es)
CN (1) CN106103424A (es)
BR (1) BR112016021257B1 (es)
CA (1) CA2942979A1 (es)
IL (1) IL247833B (es)
MX (1) MX371291B (es)
WO (1) WO2015143188A1 (es)

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WO2015143180A1 (en) 2014-03-19 2015-09-24 Viamet Pharmaceuticals, Inc. Antifungal compound process
AU2015231220B2 (en) 2014-03-19 2019-04-04 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Antifungal compound process
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Also Published As

Publication number Publication date
JP6613391B2 (ja) 2019-12-04
US20170081316A1 (en) 2017-03-23
US9914726B2 (en) 2018-03-13
MX2016012058A (es) 2017-01-19
KR102441242B1 (ko) 2022-09-07
IL247833A0 (en) 2016-11-30
BR112016021257B1 (pt) 2021-03-02
EP3119753A1 (en) 2017-01-25
WO2015143188A8 (en) 2016-09-29
WO2015143188A1 (en) 2015-09-24
EP3119753A4 (en) 2017-08-30
CN106103424A (zh) 2016-11-09
IL247833B (en) 2019-10-31
KR20160134672A (ko) 2016-11-23
JP2017512780A (ja) 2017-05-25
CA2942979A1 (en) 2015-09-24
EP3119753B1 (en) 2020-11-04

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