MX305105B - Tetrahidroazolopirazinas sulfoniladas y su uso como productos medicinales. - Google Patents

Tetrahidroazolopirazinas sulfoniladas y su uso como productos medicinales.

Info

Publication number: MX305105B
Authority: MX; Mexico
Prior art keywords: medicinal products; tetrahydroazolopyrazines; sulfonylated; sulfonylated tetrahydroazolopyrazines; medicinal
Prior art date: 2009-03-04

Application number

MX2011008864A

Other languages

English (en)

Other versions

MX2011008864A (es

Inventor

Stefan Oberboersch

Beatrix Merla

Ruth Jostock

Edward Bijsterveld

Stefan Schunk

Melanie Reich

Sabine Hees

Tieno Germann

Michael Engels

Original Assignee

Gruenenthal Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-03-04

Filing date

2010-03-03

Publication date

2012-11-12

2010-03-03 Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh

2011-09-15 Publication of MX2011008864A publication Critical patent/MX2011008864A/es

2012-11-12 Publication of MX305105B publication Critical patent/MX305105B/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Immunology (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Heart & Thoracic Surgery (AREA)
Child & Adolescent Psychology (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

MX2011008864A 2009-03-04 2010-03-03 Tetrahidroazolopirazinas sulfoniladas y su uso como productos medicinales. MX305105B (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP09003075		2009-03-04
PCT/EP2010/001299 WO2010099938A1 (en)	2009-03-04	2010-03-03	Sulfonylated tetrahydroazolopyrazines and their use as medicinal products

Publications (2)

Publication Number	Publication Date
MX2011008864A MX2011008864A (es)	2011-09-15
MX305105B true MX305105B (es)	2012-11-12

Family

ID=40716949

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MX2011008864A MX305105B (es)	2009-03-04	2010-03-03	Tetrahidroazolopirazinas sulfoniladas y su uso como productos medicinales.

Country Status (16)

Country	Link
US (1)	US8158628B2 (es)
EP (1)	EP2403854B1 (es)
JP (1)	JP2012519196A (es)
CN (1)	CN102341398A (es)
AR (1)	AR075539A1 (es)
AU (1)	AU2010220561A1 (es)
BR (1)	BRPI1010533A2 (es)
CA (1)	CA2754330A1 (es)
ES (1)	ES2437108T3 (es)
HK (1)	HK1160450A1 (es)
IL (1)	IL214911A0 (es)
MX (1)	MX305105B (es)
PL (1)	PL2403854T3 (es)
RU (1)	RU2011140061A (es)
TW (1)	TW201035102A (es)
WO (1)	WO2010099938A1 (es)

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BR112013005193A2 (pt) *	2010-09-03	2016-05-03	Gruenenthal Gmbh	derivados substituídos de tetra-hidropirrolopirazina
US8754114B2 (en)	2010-12-22	2014-06-17	Incyte Corporation	Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
DE102011082013A1 (de) *	2011-09-01	2013-03-07	Bayer Pharma AG	6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
ME03300B (me)	2012-06-13	2019-07-20	Incyte Holdings Corp	Supsтituisana triciklična jedinjenja као inhibiтori fgfr
EP2861566B1 (en)	2012-06-13	2016-12-21	F. Hoffmann-La Roche AG	New diazaspirocycloalkane and azaspirocycloalkane
WO2014026125A1 (en)	2012-08-10	2014-02-13	Incyte Corporation	Pyrazine derivatives as fgfr inhibitors
SI2900669T1 (sl)	2012-09-25	2019-12-31	F. Hoffmann-La Roche Ag	Derivati heksahidropirolo(3,4-C)pirola in sorodne spojine kot zaviralci avtotaksina (ATX) in kot zaviralci tvorbe lizofosfatidne kisline (LPA) za zdravljenje npr. bolezni ledvic
US9266892B2 (en)	2012-12-19	2016-02-23	Incyte Holdings Corporation	Fused pyrazoles as FGFR inhibitors
CN103113324B (zh) *	2013-02-07	2015-08-05	浙江工业大学	一种n-磺酰基取代的四氢吡咯类化合物的制备方法
AR095079A1 (es)	2013-03-12	2015-09-16	Hoffmann La Roche	Derivados de octahidro-pirrolo[3,4-c]-pirrol y piridina-fenilo
UA120087C2 (uk)	2013-04-19	2019-10-10	Інсайт Холдинґс Корпорейшн	Біциклічні гетероцикли як інгібітори fgfr
AR098414A1 (es)	2013-11-14	2016-05-26	Bristol Myers Squibb Co	PIPERAZINAS DE PIRAZOLO SUSTITUIDO COMO INHIBIDORES DE CASEÍNA QUINASA 1 d/e
RS56776B1 (sr)	2013-11-26	2018-04-30	Hoffmann La Roche	Derivati oktahidro-ciklobuta [1,2-c;3,4-c']dipirola kao inhibitori autotaksina
MX370659B (es)	2014-03-26	2019-12-19	Hoffmann La Roche	Compuestos bicíclicos como inhibidores de producción de autotaxina (atx) y ácido lisofosfatídico (lpa).
CA2935612A1 (en)	2014-03-26	2015-10-01	F. Hoffmann-La Roche Ag	Condensed [1,4]diazepine compounds as autotaxin (atx) and lysophosphatidic acid (lpa) production inhibitors
US10851105B2 (en)	2014-10-22	2020-12-01	Incyte Corporation	Bicyclic heterocycles as FGFR4 inhibitors
UA121669C2 (uk)	2015-02-20	2020-07-10	Інсайт Корпорейшн	Біциклічні гетероцикли як інгібітори fgfr
MA41551A (fr)	2015-02-20	2017-12-26	Incyte Corp	Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
WO2016134294A1 (en)	2015-02-20	2016-08-25	Incyte Corporation	Bicyclic heterocycles as fgfr4 inhibitors
MA41898A (fr)	2015-04-10	2018-02-13	Hoffmann La Roche	Dérivés de quinazolinone bicyclique
PE20180479A1 (es)	2015-09-04	2018-03-07	Hoffmann La Roche	Nuevos derivados de fenoximetilo
RU2724899C2 (ru)	2015-09-24	2020-06-26	Ф. Хоффманн-Ля Рош Аг	Новые бициклические соединения в качестве дуальных ингибиторов atx/ca
KR20180054830A (ko)	2015-09-24	2018-05-24	에프. 호프만-라 로슈 아게	오토탁신(atx) 억제제로서의 이환형 화합물
CR20180143A (es)	2015-09-24	2018-05-03	Hoffmann La Roche	Nuevos compuestos biciclicos como inhibidores duales de atx/ca
MA42919A (fr)	2015-09-24	2018-08-01	Hoffmann La Roche	Composés bicycliques utilisés en tant qu'inhibiteurs d'atx
JOP20190024A1 (ar)	2016-08-26	2019-02-19	Gilead Sciences Inc	مركبات بيروليزين بها استبدال واستخداماتها
CA3053329A1 (en)	2017-03-16	2018-09-20	F. Hoffmann-La Roche Ag	Heterocyclic compounds useful as dual atx/ca inhibitors
WO2018167113A1 (en)	2017-03-16	2018-09-20	F. Hoffmann-La Roche Ag	New bicyclic compounds as atx inhibitors
AR111960A1 (es)	2017-05-26	2019-09-04	Incyte Corp	Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
JP7050165B2 (ja)	2018-02-26	2022-04-07	ギリアードサイエンシーズ，インコーポレイテッド	Ｈｂｖ複製阻害剤としての置換ピロリジン化合物
SMT202400507T1 (it)	2018-05-04	2025-01-14	Incyte Corp	Forme solide di un inibitore di fgfr e procedimenti per preparare le stesse
MX2020011639A (es)	2018-05-04	2021-02-15	Incyte Corp	Sales de un inhibidor de receptores de factor de crecimiento de fibroblastos (fgfr).
WO2020185532A1 (en)	2019-03-08	2020-09-17	Incyte Corporation	Methods of treating cancer with an fgfr inhibitor
US11591329B2 (en)	2019-07-09	2023-02-28	Incyte Corporation	Bicyclic heterocycles as FGFR inhibitors
US12122767B2 (en)	2019-10-01	2024-10-22	Incyte Corporation	Bicyclic heterocycles as FGFR inhibitors
BR112022007163A2 (pt)	2019-10-14	2022-08-23	Incyte Corp	Heterociclos bicíclicos como inibidores de fgfr
WO2021076728A1 (en)	2019-10-16	2021-04-22	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
CN115151539A (zh)	2019-12-04	2022-10-04	因赛特公司	Fgfr抑制剂的衍生物
CA3163875A1 (en)	2019-12-04	2021-06-10	Incyte Corporation	Tricyclic heterocycles as fgfr inhibitors
WO2021146424A1 (en)	2020-01-15	2021-07-22	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
CA3215903A1 (en)	2021-04-12	2022-10-20	Incyte Corporation	Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent
TW202313611A (zh)	2021-06-09	2023-04-01	美商英塞特公司	作為ｆｇｆｒ抑制劑之三環雜環
WO2024201469A1 (en) *	2023-03-29	2024-10-03	Adama Agan Ltd.	Process for the preparation of amine intermediates

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US7563793B2 (en) *	2004-12-20	2009-07-21	Wyeth	Pyrrolo[1,2-a]quinoxalin-5-(4H)-yl)sulfonyls and carbonyls and their use as estrogenic agents
WO2007101007A2 (en)	2006-02-23	2007-09-07	Neurogen Corporation	Aryl sulfonyl heterocycles
JP2009534420A (ja) *	2006-04-21	2009-09-24	スミスクライン・ビーチャム・コーポレイション	Ｉｌ−８受容体アンタゴニスト
WO2007140383A2 (en)	2006-05-30	2007-12-06	Neurogen Corporation	Spirocyclic sulfonamides and related compounds
ES2436020T3 (es)	2006-09-29	2013-12-26	Grünenthal GmbH	Derivados de sulfonamida sustituidos
JP5406722B2 (ja)	2006-10-16	2014-02-05	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	ブラジキニン１受容体モジュレータとしての置換されたスルホンアミド誘導体
JP5485148B2 (ja) *	2007-06-21	2014-05-07	カラセラピューティクスインコーポレイテッド	置換イミダゾ複素環

2010
- 2010-02-26 TW TW099105566A patent/TW201035102A/zh unknown
- 2010-03-03 EP EP10708496.4A patent/EP2403854B1/en not_active Not-in-force
- 2010-03-03 MX MX2011008864A patent/MX305105B/es active IP Right Grant
- 2010-03-03 JP JP2011552360A patent/JP2012519196A/ja not_active Withdrawn
- 2010-03-03 AU AU2010220561A patent/AU2010220561A1/en not_active Abandoned
- 2010-03-03 PL PL10708496T patent/PL2403854T3/pl unknown
- 2010-03-03 RU RU2011140061/04A patent/RU2011140061A/ru not_active Application Discontinuation
- 2010-03-03 ES ES10708496.4T patent/ES2437108T3/es active Active
- 2010-03-03 WO PCT/EP2010/001299 patent/WO2010099938A1/en active Application Filing
- 2010-03-03 BR BRPI1010533A patent/BRPI1010533A2/pt not_active IP Right Cessation
- 2010-03-03 CA CA2754330A patent/CA2754330A1/en not_active Abandoned
- 2010-03-03 CN CN2010800106612A patent/CN102341398A/zh active Pending
- 2010-03-04 US US12/717,625 patent/US8158628B2/en not_active Expired - Fee Related
- 2010-03-04 AR ARP100100647A patent/AR075539A1/es not_active Application Discontinuation
2011
- 2011-09-01 IL IL214911A patent/IL214911A0/en unknown
2012
- 2012-01-26 HK HK12100745.4A patent/HK1160450A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2437108T3 (es)	2014-01-08
EP2403854B1 (en)	2013-09-11
IL214911A0 (en)	2011-11-30
MX2011008864A (es)	2011-09-15
CN102341398A (zh)	2012-02-01
BRPI1010533A2 (pt)	2016-03-15
JP2012519196A (ja)	2012-08-23
HK1160450A1 (en)	2012-08-17
US20100234387A1 (en)	2010-09-16
PL2403854T3 (pl)	2014-02-28
AU2010220561A1 (en)	2011-10-27
WO2010099938A1 (en)	2010-09-10
CA2754330A1 (en)	2010-09-10
RU2011140061A (ru)	2013-04-10
TW201035102A (en)	2010-10-01
US8158628B2 (en)	2012-04-17
EP2403854A1 (en)	2012-01-11
AR075539A1 (es)	2011-04-20

Publication	Publication Date	Title
MX305105B (es)	2012-11-12	Tetrahidroazolopirazinas sulfoniladas y su uso como productos medicinales.
IL256921A (en)	2018-03-29	Pyrazolopyrimidines, pharmaceutical preparations containing them and their use
IL253870B (en)	2018-05-31	Certain amino-pyrimidines and pharmaceutical preparations containing them
ZA201303600B (en)	2014-01-29	Composition i-ii and products and uses thereof
GB201005063D0 (en)	2010-05-12	Biological products
IL235767A (en)	2016-09-29	Preserved pyrolidines, pharmaceuticals containing them and their uses
IL221511A (en)	2015-04-30	Arilatriazolones associated with bis aryl and their use
SI2414363T1 (sl)	2014-04-30	Derivati 1-heterociklil-1,5-dihidro-pirazolo/3,4-d/pirimidin-4-ona in njihova uporaba kot modulatorji za PDE9A
GB201010193D0 (en)	2010-07-21	Medicinal use
ZA201208173B (en)	2013-07-31	Peptices and their use
IL237068A (en)	2017-12-31	1,3-dioxanomorphides and 1,3-dioxanocodides
EP2832344A4 (en)	2015-09-09	COMPOSITION AND EXTERNAL PREPARATION FOR SKIN OR FUNCTIONAL FOOD CONTAINING EACH OF THE SAME
GB0910464D0 (en)	2009-07-29	Indicator, application thereof and related products
GB0921001D0 (en)	2010-01-13	Products and uses
HK1167597A1 (en)	2012-12-07	Dodeca-2e,4e-diene amides and their use as medicaments and cosmetics -2e4e-
ZA201209595B (en)	2014-03-26	N-acetyl-dl-leucine, neuroprotective and retinoprotective medicament
IL223405B (en)	2018-11-29	Phosphoplatins, preparations containing them and their uses
IL228705A (en)	2016-11-30	Derivatives of Reliable Phenoxy-Ethyl, Pharmaceutical Preparations Containing and Using Them
GB201007202D0 (en)	2010-06-16	Product and uses
GB2504390B (en)	2015-06-03	Nutraceutical and pharmaceutical composition
PL2538955T3 (pl)	2016-04-29	Formulacja farmaceutyczna lub nutraceutyczna
HK1164193A1 (zh)	2012-09-21	抗體及其用途
PT2509443E (pt)	2014-04-07	Produto alimentar gelificado
PL2298090T3 (pl)	2016-07-29	Kompozycja farmaceutyczna lub nutraceutyczna
HRP20141173T1 (hr)	2015-01-30	Medikament koji sadrži miramistin

Legal Events

Date	Code	Title	Description
2012-11-12	FG	Grant or registration