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MX2023011670A - Formulacion estable de anticuerpo contra el receptor de oncostatina m (osmr). - Google Patents

Formulacion estable de anticuerpo contra el receptor de oncostatina m (osmr).

Info

Publication number
MX2023011670A
MX2023011670A MX2023011670A MX2023011670A MX2023011670A MX 2023011670 A MX2023011670 A MX 2023011670A MX 2023011670 A MX2023011670 A MX 2023011670A MX 2023011670 A MX2023011670 A MX 2023011670A MX 2023011670 A MX2023011670 A MX 2023011670A
Authority
MX
Mexico
Prior art keywords
osmr
oncostatin
receptor
antibody against
stable formulation
Prior art date
Application number
MX2023011670A
Other languages
English (en)
Inventor
Mark Cornell Manning
Zahra Shahrokh
Dave Nichols
Philip M Levesque
Ryan Erik Holcomb
Original Assignee
Kiniksa Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kiniksa Pharmaceuticals Ltd filed Critical Kiniksa Pharmaceuticals Ltd
Publication of MX2023011670A publication Critical patent/MX2023011670A/es

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    • C—CHEMISTRY; METALLURGY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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Abstract

La presente invención proporciona, entre otras cosas, formulaciones estables que comprenden un anticuerpo contra el receptor de oncostatina M (OSMR) y que tienen un pH en el intervalo de aproximadamente 6.0 - 7.6, en donde menos de aproximadamente 5 % del anticuerpo contra OSMR existe como especies de alto peso molecular (HMW) en la formulación.
MX2023011670A 2017-04-11 2019-10-11 Formulacion estable de anticuerpo contra el receptor de oncostatina m (osmr). MX2023011670A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762484260P 2017-04-11 2017-04-11
US201762524927P 2017-06-26 2017-06-26

Publications (1)

Publication Number Publication Date
MX2023011670A true MX2023011670A (es) 2023-10-18

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Family Applications (2)

Application Number Title Priority Date Filing Date
MX2019012255A MX2019012255A (es) 2017-04-11 2018-04-11 Formulacion estable de anticuerpo contra el receptor de oncostatina m (osmr).
MX2023011670A MX2023011670A (es) 2017-04-11 2019-10-11 Formulacion estable de anticuerpo contra el receptor de oncostatina m (osmr).

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MX2019012255A MX2019012255A (es) 2017-04-11 2018-04-11 Formulacion estable de anticuerpo contra el receptor de oncostatina m (osmr).

Country Status (11)

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US (4) US10493149B2 (es)
EP (1) EP3609916A1 (es)
JP (2) JP7398958B2 (es)
KR (1) KR20200014738A (es)
CN (2) CN110662761B (es)
AU (1) AU2018251808A1 (es)
BR (1) BR112019021364A2 (es)
CA (1) CA3061705A1 (es)
MA (1) MA53466A (es)
MX (2) MX2019012255A (es)
WO (1) WO2018191414A1 (es)

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Publication number Priority date Publication date Assignee Title
ES2692657T3 (es) 2013-05-30 2018-12-04 Kiniksa Pharmaceuticals, Ltd. Proteínas de enlace al antígeno del receptor de oncastatina
EP3284480A4 (en) 2015-04-14 2018-12-05 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition for prevention and/or treatment of atopic dermatitis containing il-31 antagonist as active ingredient
JP2022513693A (ja) * 2018-11-29 2022-02-09 ハーバー・バイオメド・セラピューティクス・リミテッド 抗ｐｄ－ｌ１抗体製剤
CA3156713A1 (en) * 2019-11-20 2021-05-27 Daisuke Kameoka Antibody-containing preparation
TW202221039A (zh) 2020-10-19 2022-06-01 美商碩騰服務公司 犬及貓抑瘤素Ｍ受體β之抗體及其用途
CN113274494B (zh) * 2021-06-07 2022-09-20 武汉生物制品研究所有限责任公司 一种抗SARS-CoV-2的重组全人源单克隆抗体的液体制剂

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ZA912136B (en) * 1990-03-29 1992-11-25 Bristol Myers Squibb Co Anti-oncostatin m monoclonal antibodies
MX2007014148A (es) * 2005-05-19 2008-01-11 Amgen Inc Composiciones y metodos para incrementar la estabilidad de anticuerpos.
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US20200061188A1 (en) 2020-02-27
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US20180333489A1 (en) 2018-11-22
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