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MX2023006058A - Sistemas y metodos para tratar fluidos biologicos. - Google Patents

Sistemas y metodos para tratar fluidos biologicos.

Info

Publication number
MX2023006058A
MX2023006058A MX2023006058A MX2023006058A MX2023006058A MX 2023006058 A MX2023006058 A MX 2023006058A MX 2023006058 A MX2023006058 A MX 2023006058A MX 2023006058 A MX2023006058 A MX 2023006058A MX 2023006058 A MX2023006058 A MX 2023006058A
Authority
MX
Mexico
Prior art keywords
systems
methods
biological fluids
treating biological
treating
Prior art date
Application number
MX2023006058A
Other languages
English (en)
Inventor
Adonis Stassinopoulos
Peter Bringmann
Maria Felicia Santa
Daniel Church
Grace Castro
Thea Lu
Shelby Reinhardt
Original Assignee
Cerus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerus Corp filed Critical Cerus Corp
Publication of MX2023006058A publication Critical patent/MX2023006058A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0047—Ultraviolet radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
    • B01J19/12—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing electromagnetic waves
    • B01J19/122—Incoherent waves
    • B01J19/123—Ultraviolet light
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/124—Disinfecting agents, e.g. antimicrobials
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/168—Physical preservation processes using electromagnetic fields or radiation; using acoustic waves or corpuscular radiation
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
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    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0076—Radiation using a photocatalyst or photosensitiser
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    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
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    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
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    • A—HUMAN NECESSITIES
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    • A61L2/26—Accessories or devices or components used for biocidal treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L25/00—Assemblies consisting of a plurality of semiconductor or other solid state devices
    • H01L25/03—Assemblies consisting of a plurality of semiconductor or other solid state devices all the devices being of a type provided for in a single subclass of subclasses H10B, H10F, H10H, H10K or H10N, e.g. assemblies of rectifier diodes
    • H01L25/04—Assemblies consisting of a plurality of semiconductor or other solid state devices all the devices being of a type provided for in a single subclass of subclasses H10B, H10F, H10H, H10K or H10N, e.g. assemblies of rectifier diodes the devices not having separate containers
    • H01L25/075—Assemblies consisting of a plurality of semiconductor or other solid state devices all the devices being of a type provided for in a single subclass of subclasses H10B, H10F, H10H, H10K or H10N, e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in group H10H20/00
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L25/00—Assemblies consisting of a plurality of semiconductor or other solid state devices
    • H01L25/03—Assemblies consisting of a plurality of semiconductor or other solid state devices all the devices being of a type provided for in a single subclass of subclasses H10B, H10F, H10H, H10K or H10N, e.g. assemblies of rectifier diodes
    • H01L25/04—Assemblies consisting of a plurality of semiconductor or other solid state devices all the devices being of a type provided for in a single subclass of subclasses H10B, H10F, H10H, H10K or H10N, e.g. assemblies of rectifier diodes the devices not having separate containers
    • H01L25/075—Assemblies consisting of a plurality of semiconductor or other solid state devices all the devices being of a type provided for in a single subclass of subclasses H10B, H10F, H10H, H10K or H10N, e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in group H10H20/00
    • H01L25/0753—Assemblies consisting of a plurality of semiconductor or other solid state devices all the devices being of a type provided for in a single subclass of subclasses H10B, H10F, H10H, H10K or H10N, e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in group H10H20/00 the devices being arranged next to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/24—Apparatus using programmed or automatic operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10—Apparatus features
    • A61L2202/11—Apparatus for generating biocidal substances, e.g. vaporisers, UV lamps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10—Apparatus features
    • A61L2202/12—Apparatus for isolating biocidal substances from the environment
    • A61L2202/122—Chambers for sterilisation
    • A—HUMAN NECESSITIES
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10—Apparatus features
    • A61L2202/14—Means for controlling sterilisation processes, data processing, presentation and storage means, e.g. sensors, controllers, programs
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/22—Blood or products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
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    • A61M2202/0413—Blood
    • A61M2202/0415—Plasma
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0427—Platelets; Thrombocytes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Power Engineering (AREA)
  • Biomedical Technology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Molecular Biology (AREA)
  • Electromagnetism (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Computer Hardware Design (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se proporcionan sistemas y métodos para tratar un fluido biológico, por ejemplo, para inactivar patógenos.
MX2023006058A 2017-12-29 2020-07-13 Sistemas y metodos para tratar fluidos biologicos. MX2023006058A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762612314P 2017-12-29 2017-12-29

Publications (1)

Publication Number Publication Date
MX2023006058A true MX2023006058A (es) 2023-07-31

Family

ID=65139275

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020006881A MX2020006881A (es) 2017-12-29 2018-12-28 Sistemas y metodos para tratar fluidos biologicos.
MX2023006058A MX2023006058A (es) 2017-12-29 2020-07-13 Sistemas y metodos para tratar fluidos biologicos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2020006881A MX2020006881A (es) 2017-12-29 2018-12-28 Sistemas y metodos para tratar fluidos biologicos.

Country Status (16)

Country Link
US (2) US11554185B2 (es)
EP (1) EP3731960A1 (es)
JP (2) JP7311518B2 (es)
KR (1) KR20200115498A (es)
CN (2) CN116571191A (es)
AU (1) AU2018395525B2 (es)
BR (1) BR112020013178A2 (es)
CA (1) CA3087253A1 (es)
CO (1) CO2020009340A2 (es)
EA (1) EA202091602A1 (es)
IL (1) IL275698B2 (es)
MX (2) MX2020006881A (es)
SG (1) SG11202006158TA (es)
TW (1) TWI821233B (es)
UA (1) UA129421C2 (es)
WO (1) WO2019133929A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4410318A3 (en) 2015-06-26 2024-10-09 Cerus Corporation Cryoprecipitate compositions and methods of preparation thereof
WO2017070619A1 (en) 2015-10-23 2017-04-27 Cerus Corporation Plasma compositions and methods of use thereof
CN110268264B (zh) 2016-12-23 2024-07-02 塞鲁斯公司 使用化合物结合的基材测试和筛选的系统和方法
WO2018161020A1 (en) 2017-03-03 2018-09-07 Cerus Corporation Kits and methods for preparing pathogen-inactivated platelet compositions
AU2018395525B2 (en) 2017-12-29 2023-09-14 Cerus Corporation Systems and methods for treating biological fluids
CA3113655A1 (en) * 2018-09-20 2020-03-26 Cerus Corporation Methods and kits for preparing pathogen-inactivated whole blood
TWI728589B (zh) * 2019-12-12 2021-05-21 國立臺灣大學 以熱作用於活體組織的方法及裝置
CN114173842A (zh) 2019-06-22 2022-03-11 塞鲁斯公司 生物流体处理系统
US11498046B2 (en) * 2019-06-27 2022-11-15 Phoseon Technology, Inc. Method and system for tetrachloromethane synthesis
CN114269394A (zh) 2019-06-28 2022-04-01 塞鲁斯公司 用于实现生物流体处理装置的系统和方法
CN111840596B (zh) * 2020-06-11 2022-03-11 南岳生物制药有限公司 核黄素光化学血浆灭活装置及其控制系统、控制方法
EP3957333A1 (de) * 2020-08-19 2022-02-23 Analytik Jena GmbH Uv-modul, system und verfahren zur deaktivierung von biologisch kontaminierten oberflächen in einem inneraum eines geräts
CN116322823B (zh) * 2020-10-14 2025-06-13 大塚电子株式会社 具备用于血液的冷却水循环部的光线力学疗法装置
JP2023546165A (ja) * 2020-10-19 2023-11-01 シーラス コーポレイション 生物学的流体処理システム用のモジュール式光装置
CN112316166B (zh) * 2020-10-30 2022-07-12 中国医学科学院输血研究所 一种生物液体样本中病原体的核黄素光化学灭活方法
US20240082441A1 (en) * 2021-01-21 2024-03-14 Signify Holding B.V. A light emitting system for disinfecting a target area
US20220354140A1 (en) * 2021-05-05 2022-11-10 Saltbrick Retail, LLC Process for dry aging meat
CN113877485B (zh) * 2021-10-18 2025-02-14 江苏汉邦科技股份有限公司 一种核酸合成仪
FR3138040A1 (fr) 2022-07-21 2024-01-26 Maco Pharma Appareil et procédé pour irradier un fluide biologique
AT526979A1 (de) * 2023-02-28 2024-09-15 Sallinger Mst Eur Ing Peter Vorrichtung, Verfahren und Anordnung zur Behandlung des Abfallfluids einer hämatologischen Analysevorrichtung
WO2024206151A1 (en) * 2023-03-24 2024-10-03 Colorado State University Research Foundation System for real-time measurement of photochemical production systems
US12312256B2 (en) 2023-04-21 2025-05-27 Soletluna Holdings, Inc. Device that treats water and/or at least one chromophore with multiple wavelengths of light and sound
US20240351917A1 (en) * 2023-04-21 2024-10-24 Soletluna Holdings, Inc. Device that treats water with multiple wavelengths of light and sound
US11820675B1 (en) * 2023-04-21 2023-11-21 Soletluna Holdings, Inc. Device that treats water with multiple wavelengths of light
US12285625B2 (en) * 2023-06-12 2025-04-29 Soletluna Holdings, Inc. Light therapy device that treats a subject with multiple wavelengths of light

Family Cites Families (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556958A (en) * 1989-10-26 1996-09-17 Steritech, Inc. Inactivation of pathogens in clinical samples
US5221608A (en) * 1989-10-26 1993-06-22 Cimino George D Methods for rendering amplified nucleic acid subsequently unamplifiable
US5418130A (en) 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
US5232844A (en) 1990-05-15 1993-08-03 New York Blood Center Photodynamic inactivation of viruses in cell-containing compositions
US5167656A (en) 1991-01-22 1992-12-01 Baxter International Inc. Blood container having lay-flat sample reservoir
DE9102709U1 (de) 1991-03-07 1991-05-23 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Oldenburg und Bremen Gemeinnützige GmbH, 3257 Springe Blutbeutelanordnung
EP0544895B1 (en) 1991-06-21 1997-08-27 Baxter International Inc. Method for inactivating pathogens in a body fluid
US5618662A (en) 1992-03-02 1997-04-08 Cerus Corporation Intravenous administration of psoralen
US5459030A (en) 1992-03-02 1995-10-17 Steritech, Inc. Synthetic media compositions for inactivating bacteria and viruses in blood preparations with 8-methoxypsoralen
AU4107396A (en) 1992-03-02 1996-06-06 Cerus Corporation Synthetic media for blood components
US5709991A (en) 1992-03-02 1998-01-20 Cerus Corporation Proralen inactivation of microorganisms and psoralen removal
US5288605A (en) 1992-03-02 1994-02-22 Steritech, Inc. Methods for inactivating bacteria in blood preparations with 8-methoxypsoralen
US6433343B1 (en) 1992-03-02 2002-08-13 Cerus Corporation Device and method for photoactivation
DE69328685T2 (de) 1992-08-07 2000-11-23 Cerus Corp., Concord Verfahren zur inaktivierung von bakterien in blutpräparaten mit hilfe von methoxypsoralen
FR2696095B1 (fr) 1992-09-30 1994-11-25 Inoteb Colle biologique à base de protéines coagulables par la thrombine, enrichie en facteurs plaquettaires, sa préparation et son application.
WO1994020090A1 (en) 1993-03-17 1994-09-15 Steritech, Inc. Decontaminating clinical samples
EP0702719B1 (en) 1993-05-28 2005-08-03 New York Blood Center, Inc. Process for the sterilization of biological compositions and the product produced thereby
US5871900A (en) 1993-06-28 1999-02-16 Cerus Corporation Method of inactivating pathogens in biological fluids using photoactivated 5-primaryamino psoralens
US6004742A (en) 1993-06-28 1999-12-21 Cerus Corporation Method for inactivation of pathogens in platelets using 4' and 5' primary amino-substituted psoralens
US5593823A (en) 1993-06-28 1997-01-14 Cerus Corporation Method for inactivating pathogens in blood using photoactivation of 4'-primary amino-substituted psoralens
US6420570B1 (en) 1993-06-28 2002-07-16 Cerus Corporation Psoralen compounds
US6004741A (en) * 1993-06-28 1999-12-21 Cerus Corporation Method for the photoactivation of 4' and 5' primary aminoalkyl psoralens in platelet preparations
US5399719A (en) 1993-06-28 1995-03-21 Steritech, Inc. Compounds for the photodecontamination of pathogens in blood
US5712085A (en) 1993-06-28 1998-01-27 Cerus Corporation 5'-(4-amino-2-oxa)butye-4,4', 8-trinethylpsoralen in synthetic medium
RU2118177C1 (ru) 1993-08-02 1998-08-27 Алексей Борисович Башкиров Способ индукции иммунного ответа организма
DE69432832T2 (de) 1993-11-10 2004-05-06 Cerus Corp., Concord Vorrichtung und verfahren zur photoaktivierung
AU691672B2 (en) 1994-09-22 1998-05-21 Baxter International Inc. Photodynamic inactivation of viral and bacterial blood contaminants with halogenated coumarin and furocoumarin sensitizers
US5691132A (en) 1994-11-14 1997-11-25 Cerus Corporation Method for inactivating pathogens in red cell compositions using quinacrine mustard
US6177441B1 (en) 1995-06-05 2001-01-23 Cerus Corporation Treating red blood cell solutions with anti-viral agents
US6544727B1 (en) 1995-06-07 2003-04-08 Cerus Corporation Methods and devices for the removal of psoralens from blood products
CA2199731A1 (en) 1995-06-07 1996-12-19 Susan Wollowitz Treating red blood cell solutions with anti-viral agents
AU6267496A (en) 1995-06-07 1996-12-30 Steritech, Inc. Methods of inactivating leukocytes and inhibiting cytokine p roduction in blood products
DE69638094D1 (de) 1995-06-07 2010-01-21 Cerus Corp Verfahren und vorrichtungen zur entfernung von psoralenen aus blutprodukten.
US20020192632A1 (en) 1995-06-07 2002-12-19 Hei Derek J. Method and devices for the removal of psoralens from blood products
WO1997021346A1 (en) 1995-12-14 1997-06-19 Cerus Corporation Inactivation of non-enveloped virus
US6228995B1 (en) 1996-04-09 2001-05-08 Therakos, Inc. Method for removal of psoralens from biological fluids
US20020115585A1 (en) 1996-06-07 2002-08-22 Hei Derek J. Method and devices for the removal of psoralens from blood products
US6190855B1 (en) 1996-10-28 2001-02-20 Baxter International Inc. Systems and methods for removing viral agents from blood
US6190609B1 (en) 1996-11-19 2001-02-20 Baxter International Inc. Methods and apparatus for inactivating contaminants in biological fluid
EP1021414B1 (en) 1997-01-06 2003-06-18 Cerus Corporation Frangible compounds for pathogen inactivation
EP0954374B1 (en) 1997-01-06 2004-11-24 Cerus Corporation Adsorbens and devices for the reduction of small organic compounds from blood products
US6093725A (en) 1997-01-06 2000-07-25 Cerus Corporation Frangible compounds for pathogen inactivation
US6514987B1 (en) 1997-01-06 2003-02-04 Cerus Corporation Frangible compounds for pathogen inactivation
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
CA2296366A1 (en) 1997-07-21 1999-01-28 Cerus Corporation Method of treating leukocytes, leukocyte compositions and methods of use thereof
AU747842B2 (en) 1997-11-20 2002-05-23 Cerus Corporation New psoralens for pathogen inactivation
CA2318508C (en) 1998-01-06 2004-04-20 Cerus Corporation Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US7611831B2 (en) 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
AU745209B2 (en) 1998-01-06 2002-03-14 Cerus Corporation Methods for quenching pathogen inactivators in biological materials
EP1085880A2 (en) 1998-06-11 2001-03-28 Cerus Corporation Use of alkylating compounds for inhibiting proliferation of arterial smooth muscle cells
US6277337B1 (en) 1998-07-21 2001-08-21 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using photosensitizers
US7068361B2 (en) 1999-06-03 2006-06-27 Baxter International Apparatus, systems and methods for processing and treating a biological fluid with light
US6565802B1 (en) 1999-06-03 2003-05-20 Baxter International Inc. Apparatus, systems and methods for processing and treating a biological fluid with light
US7025877B1 (en) 1999-06-03 2006-04-11 Baxter International Inc. Processing set for processing and treating a biological fluid
US7445756B2 (en) 1999-06-03 2008-11-04 Fenwal, Inc. Fluid processing sets and organizers for the same
US6494753B1 (en) 1999-08-02 2002-12-17 Swenco Products, Inc. No-crimp electrical connector side-by-side type and method
JP2003534383A (ja) 2000-05-31 2003-11-18 セラス コーポレイション 免疫原性が減少した赤血球の病原体不活性化溶液の調製
US6843961B2 (en) * 2000-06-15 2005-01-18 Gambro, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
JP4412441B2 (ja) 2000-07-11 2010-02-10 日本電気株式会社 液晶表示装置
AU2007237275A1 (en) * 2000-11-13 2008-01-10 Bayer Aktiengesellschaft Method of inactivating microorganisms in a fluid using ultraviolet radiation
CA2434256A1 (en) 2000-12-21 2003-07-31 David Cook Methods for inactivation of pathogens in biological materials
US7381976B2 (en) * 2001-03-13 2008-06-03 Triton Thalassic Technologies, Inc. Monochromatic fluid treatment systems
US20030207247A1 (en) 2001-12-05 2003-11-06 Cerus Corporation Preparation of red blood cells having reduced immunogenicity
US7264608B2 (en) 2001-12-05 2007-09-04 Fenwal, Inc. Manual processing systems and methods for providing blood components conditioned for pathogen inactivation
AU2003215084A1 (en) 2002-02-06 2003-09-02 The Johns Hopkins University Methods and compositions for the targeting of a systemic immune response to specific organs or tissues
AU2003213758A1 (en) 2002-03-14 2003-09-29 Fenwal, Inc. Compound removal device
US20030215785A1 (en) 2002-04-26 2003-11-20 Gambro, Inc. Solution containing platelet activation inhibitors for pathogen reducing and storing blood platelets
AU2003259109A1 (en) 2002-07-12 2004-02-02 The Johns Hopkins University Mesothelin vaccines and model systems
WO2004018471A1 (en) 2002-08-23 2004-03-04 Gambro, Inc. Nucleic acid damage using riboflavin and light
US20040088189A1 (en) 2002-11-06 2004-05-06 Veome Edmond A. System and method for monitoring , reporting, managing and administering the treatment of a blood component
WO2004050029A2 (en) 2002-12-04 2004-06-17 Cerus Corporation Novel activated polyethylene glycol compounds
EP1592441B1 (en) 2003-02-06 2012-04-11 Aduro Biotech Listeria attenuated for entry into non-phagocytic cells, vaccines comprising the listeria, and methods of use thereof
AU2004224425B2 (en) 2003-02-06 2010-06-24 Aduro Biotech Modified free-living microbes, vaccine compositions and methods of use thereof
US7695725B2 (en) 2003-02-06 2010-04-13 Aduro Biotech Modified free-living microbes, vaccine compositions and methods of use thereof
DE10323843A1 (de) 2003-05-23 2004-12-23 Fresenius Medical Care Deutschland Gmbh Blutbehandlungsgerät
GB0313742D0 (en) 2003-06-13 2003-07-16 Curry Charles E Valve diagnostic tool
JP2007509067A (ja) 2003-10-15 2007-04-12 メディミューン，インコーポレーテッド リステリアに基づくＥｐｈＡ２ワクチン
US7842289B2 (en) 2003-12-24 2010-11-30 Aduro Biotech Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof
WO2005067460A2 (en) 2003-12-24 2005-07-28 Medimmune, Inc. Epha2 vaccines
AU2004314347B2 (en) 2003-12-24 2011-05-19 Aduro Biotech, Inc. Recombinant nucleic acid molecules encoding fusion proteins comprising antigens and bacterial secretory signal polypeptides, expression cassettes, and bacteria, and methods of use thereof
US20070031457A1 (en) 2004-02-06 2007-02-08 Dubensky Thomas W Jr Modified Bacillus anthracis, vaccine compositions and methods of use thereof
WO2005092372A2 (en) 2004-02-06 2005-10-06 Cerus Corporation Modified bacillus anthracis vaccine compositions and methods of use thereof
US8296071B2 (en) 2004-03-15 2012-10-23 Terumo Bct Biotechnologies, Llc Methods for uniformly treating biological samples with electromagnetic radiation
US7993580B2 (en) 2004-08-24 2011-08-09 Baxter International Inc. Methods for the inactivation of microorganisms in biological fluids, flow through reactors and methods of controlling the light sum dose to effectively inactivate microorganisms in batch reactors
PT1838355E (pt) 2004-10-29 2013-11-07 Cerus Corp Métodos de inibição melhorados destinados a um processo de inativação de glóbulos vermelhos
US20070190029A1 (en) 2005-08-19 2007-08-16 Cerus Corporation Listeria-induced immunorecruitment and activation, and methods of use thereof
US20070190063A1 (en) 2005-08-19 2007-08-16 Bahjat Keith S Antibody-mediated enhancement of immune response
US20070207171A1 (en) 2006-03-01 2007-09-06 Cerus Corporation Engineered listeria and methods of use thereof
WO2007103261A2 (en) 2006-03-01 2007-09-13 Medimmune, Inc. Listeria-based epha2 immunogenic compositions
WO2007117371A2 (en) 2006-03-01 2007-10-18 Anza Therapeutics, Inc. Engineered listeria and methods of use thereof
US7935804B2 (en) 2006-03-01 2011-05-03 Aduro Biotech Engineered Listeria and methods of use thereof
EP1991263B8 (en) 2006-03-01 2015-02-25 Aduro Biotech Engineered listeria and methods of use thereof
EP2079830B1 (en) * 2006-10-04 2016-08-17 Janssen Pharmaceutica NV Preparation of inactivated artificial antigen presenting cells and their use in cell therapies
US10596387B2 (en) * 2007-04-08 2020-03-24 Immunolight, Llc. Tumor imaging with X-rays and other high energy sources using as contrast agents photon-emitting phosphors having therapeutic properties
US8506886B2 (en) 2007-06-20 2013-08-13 Uvcleaning Systems, Inc. Ultraviolet photoreactor for the purification of fluids
EP2008669A1 (en) 2007-06-22 2008-12-31 Maco Pharma S.A. Irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid and process
US7829867B2 (en) 2007-07-02 2010-11-09 Caridianbct Biotechnologies, Llc Apparatus for photo reduction of contaminants in blood and blood products with calibration means
KR101896430B1 (ko) 2008-04-09 2018-09-10 세루스 코포레이션 적혈구 병원체 불활성화를 위한 개선된 퀀칭 방법
CN106421864A (zh) 2009-01-29 2017-02-22 S·E·内斯特尔 用于在空气和表面中产生高水平消毒作用的改善的方法和设备
US8715920B2 (en) 2010-07-27 2014-05-06 Biovec Transfusion, Llc Composition for preserving platelets during photosensitization
US8877060B2 (en) 2010-11-23 2014-11-04 Biovec Transfusion, Llc Methods for removing pathogens from a platelet preparation
WO2011119950A2 (en) 2010-03-26 2011-09-29 Aquionics, Inc. Ultraviolet disinfection of oil field process water
TWI518736B (zh) * 2010-03-31 2016-01-21 Ａｔｓ自動模具系統股份有限公司 光產生系統及其方法
US9024292B2 (en) 2012-06-02 2015-05-05 Xiaohang Li Monolithic semiconductor light emitting devices and methods of making the same
US20140086793A1 (en) 2012-09-25 2014-03-27 Hemalux Technologies LLC Systems and methods for reduction of pathogens in a biological fluid using variable fluid flow and ultraviolet light irradiation
CN203017432U (zh) * 2013-01-21 2013-06-26 中国人民解放军总医院 一种流动式血浆病毒灭活设备
AU2014223268A1 (en) 2013-03-01 2015-09-17 Klox Technologies Inc. Phototherapeutic device, method and use
US9415126B2 (en) * 2013-05-23 2016-08-16 Sensor Electronic Technology, Inc. Reflective transparent optical chamber
US20140353519A1 (en) 2013-05-28 2014-12-04 ELKO Electronic Products Corp. Attached germicidal lamp assembly
JP2017077247A (ja) 2014-03-07 2017-04-27 国立大学法人東京農工大学 ノロウイルスの不活性化方法、ノロウイルス不活性化用発光ダイオード、およびノロウイルスの不活性化装置
WO2015168768A1 (en) 2014-05-05 2015-11-12 Sanuvox Technologies Inc. Room decontamination system, method and controller
CN107075478B (zh) 2014-07-23 2021-11-09 塞鲁斯公司 制备血小板制品的方法
EP3204426B1 (en) 2014-10-10 2020-11-25 Cerus Corporation Compositions for use in treating viral hemorrhagic fever
PL3720099T3 (pl) 2014-10-17 2024-07-22 Gambro Lundia Ab Sposób zapewnienia danych operacyjnych do urządzenia medycznego do przetwarzania płynów przy użyciu akcesorium medycznego oraz akcesorium medyczne
US20180185484A1 (en) 2015-01-16 2018-07-05 Cerus Corporation Preparation and use of platelet products
US9937274B2 (en) * 2015-03-18 2018-04-10 GE Lighting Solutions, LLC Light disinfection system and method
EP4410318A3 (en) 2015-06-26 2024-10-09 Cerus Corporation Cryoprecipitate compositions and methods of preparation thereof
US20180185566A1 (en) 2015-07-02 2018-07-05 Gambro Lundia Ab Human-shaped graphical element for medical treatment user interfaces
US20170014538A1 (en) 2015-07-14 2017-01-19 Juha Rantala LED structure and luminaire for continuous disinfection
US20170028121A1 (en) 2015-07-31 2017-02-02 Fenwal, Inc. Irradiation device for biological fluids
WO2017062260A2 (en) 2015-10-02 2017-04-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Inactivation of pathogens in ex vivo blood products in storage bags using visible light
WO2017070619A1 (en) 2015-10-23 2017-04-27 Cerus Corporation Plasma compositions and methods of use thereof
WO2017120545A2 (en) 2016-01-07 2017-07-13 Cerus Corporation Systems and methods for preparation of platelets
US10561753B2 (en) 2016-03-02 2020-02-18 Asp Global Manufacturing Gmbh Method of sterilizing medical devices, analyzing biological indicators, and linking medical device sterilization equipment
EP3434295B1 (en) 2016-03-23 2022-03-09 Terumo Kabushiki Kaisha Light irradiation device
WO2018080805A1 (en) 2016-10-24 2018-05-03 Phoseon Technology, Inc. Systems and methods for bio-inactivation
US10751433B2 (en) 2016-11-28 2020-08-25 Fenwal, Inc. Systems and methods for controlling an irradiation device
CN110268264B (zh) 2016-12-23 2024-07-02 塞鲁斯公司 使用化合物结合的基材测试和筛选的系统和方法
WO2018125994A1 (en) 2016-12-31 2018-07-05 Cerus Corporation Compositions and methods for preparation of red blood cells
WO2018161020A1 (en) 2017-03-03 2018-09-07 Cerus Corporation Kits and methods for preparing pathogen-inactivated platelet compositions
IL273433B2 (en) 2017-09-20 2025-01-01 Cerus Corp Compositions and methods for inactivating platelet pathogens
US11124750B2 (en) * 2017-09-30 2021-09-21 Sensor Electronic Technology, Inc. Ultraviolet irradiation of fluids
AU2018395525B2 (en) 2017-12-29 2023-09-14 Cerus Corporation Systems and methods for treating biological fluids
CA3113655A1 (en) 2018-09-20 2020-03-26 Cerus Corporation Methods and kits for preparing pathogen-inactivated whole blood
EP3987533A1 (en) 2019-06-22 2022-04-27 Cerus Corporation Systems and methods for implementing treatment of biological fluids
CN114173842A (zh) 2019-06-22 2022-03-11 塞鲁斯公司 生物流体处理系统
CN114269394A (zh) 2019-06-28 2022-04-01 塞鲁斯公司 用于实现生物流体处理装置的系统和方法
US12290624B2 (en) 2019-08-09 2025-05-06 Fenwal, Inc. System and method for irradiating biological fluids
US11577016B2 (en) 2019-08-20 2023-02-14 Fenwal, Inc. System and method for irradiating biological fluids
JP2023546165A (ja) 2020-10-19 2023-11-01 シーラス コーポレイション 生物学的流体処理システム用のモジュール式光装置

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